Department of Molecular Cell Biology

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Dr. Leeat Yankielowicz-Keren
Systems tissue pathology

Prof. Shalev Itzkovitz
Systems Biology of Mammalian Tissues

Prof. Yonatan Stelzer
Epigenetics in development and disease

Prof. Ravid Straussman
The study of resistance to anti-cancer therapy

Prof. Yardena Samuels
Melanoma Functional Genomics

Prof. Valery Krizhanovsky
Cellular senescence in tissue damage cancer and aging

Prof. Oren Schuldiner
Mechanisms of neuronal remodeling

Prof. Eran Segal
Developing Computational Models for Personalized Medicine

Prof. Sima Lev
Cell Signaling in Cancer Development and Metastasis

Prof. Gil Levkowitz
Linking genes, development and function of the zebrafish hypothalamus

Prof. Itay Tirosh
Tumor Systems Biology

Prof. Yehiel Zick
Cross talk between insulin resistance, animal lectins and bone remodeling

Prof. Elior Peles
Development of myelinated nerves

Prof. Moshe Oren
Molecular and cellular biology of cancer

Prof. Eldad Tzahor
Cardiomyocyte cell-cycle control and dedifferentiation

Prof. Varda Rotter
The role of p53 in maintaining genomic plasticity

Prof. Uri Alon
Systems biology and physics of behavior

Research in our department centers around molecular mechanisms that control different aspects of cell biology during development and disease states. Large part of the research focuses on cancer heterogeneity at both genomics, proteomics, and the cancer microbiome. We bring unique and innovative research approaches that shed light on organ function in vivo, such as heart, liver, pancreas, gut, and the nervous system. Studies at the department explore diverse cell biology topics including cell-cell communication, cytoskeletal organization; intracellular signaling; senescence, differentiation; physiology and metabolism.

Latest PUBLICATIONS

Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome

Vendramin R., Fu H., Fernandez Patel S., Zhao Y., Qian D., Ligammari L., Bartok O., Greenberg P., Levy R., Castro A., Thakkar K., Murai J., Lu W. T., Sng C. C., Weller C., Beattie G., Bhamra A., Farriol-Duran R., Karagianni D. & Samuels Y. (2026), Immunity

CAUSAL REPRESENTATION LEARNING FROM MULTI-MODAL BIOMEDICAL OBSERVATIONS

Sun Y., Kong L., Chen G., Li L., Luo G., Li Z., Zhang Y., Zheng Y., Yang M., Stojanov P., Segal E., Xing E. P. & Zhang K. (2025), 13th International Conference on Learning Representations, ICLR 2025. p. 41855-41887

A minimal mathematical model of red blood cell homeostasis in anemia

Dor H. & Alon U. (2026), PLoS Computational Biology. 22, 3, e1014111

Disruption of the developmental factor Otp in the adult male forebrain reveals its diverse physiological functions

Tahor M., Kuperman Y., Nahum T., Tsoory M., Bejar B., Regev E., Blechman J., Biran J., Chen A. & Levkowitz G. (2026), Endocrinology. 167, 4, bqag029

Dietmicrobiome associations in 10,068 individuals from the Human Phenotype Project to guide personalized nutrition

Segev T., Barak D., Zahavi L., Godneva A., Rein M., Krongauz D., Samocha-Bonet D., Rossman H., Weinberger A. & Segal E. (2026), Nature Medicine

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news

Date: February 17, 2026

Congratulations to Prof. Yardena Samuels

Gustave Roussy Scientific Advisory Board
Date: February 5, 2026

Congratulations to Prof. Uri Alon

IUPAP Medal for the Physics of Life.
Read more about Congratulations to Prof. Uri Alon
Date: January 15, 2026

Congratulations to Prof. Oren Schuldiner

TUM Ambassador