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Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YAL056W
    below threshold
    17.1
  • N' NOP1pr-GFP in SD
    YAL056W
    cytosol,punctate
    50.3316
  • N' TEF2pr-mCherry in SD
    YAL056W
    cytosol
    36.3945
  • N' NATIVEpr-GFP in SD
    YAL056W
    cytosol
    23.8982
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YAL056W
    cytosol
    17.85
    1.04
    No
  • C’ GFP library in SD+H2O2
    YAL056W
    cytosol
    16.47
    0.96
    No
  • C’ GFP library in Starvation Media
    YAL056W
    cytosol
    18.16
    1.06
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    17.4322
    1.01897
    No