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Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YDR227W
    nuclear periphery
    20.63
  • N' NOP1pr-GFP in SD
    YDR227W
    punctate,nucleus
    49.5599
  • N' TEF2pr-mCherry in SD
    YDR227W
    nucleus
    16.8144
  • N' NATIVEpr-GFP in SD
    YDR227W
    punctate,nuclear periphery
    32.0982
  • N' TEF2pr-VC and Cyto-VN in SD
    YDR227W
    nucleus
    27.2266
  • C’ GFP library in SD+DTT 
    YDR227W
    nuclear periphery
    19.27
    0.93
    No
  • C’ GFP library in SD+H2O2
    YDR227W
    nuclear periphery
    25.16
    1.21
    No
  • C’ GFP library in Starvation Media
    YDR227W
    nuclear periphery
    19.27
    0.93
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    nuclear periphery
  • C’ GFP library on the background of CCT mutant
    noimage.png
    nuclear periphery
    21.9895
    1.06559
    No