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Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YGL086W
    nuclear periphery
    22.54
  • N' NOP1pr-GFP in SD
    YGL086W
    punctate,nuclear periphery
    26.1212
  • N' TEF2pr-mCherry in SD
    YGL086W
    punctate
    7.52787
  • N' NATIVEpr-GFP in SD
    YGL086W
    cytosol
    20.0236
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YGL086W
    nuclear periphery
    23.49
    1.04
    No
  • C’ GFP library in SD+H2O2
    YGL086W
    nuclear periphery
    25
    1.1
    No
  • C’ GFP library in Starvation Media
    YGL086W
    nuclear periphery
    19.48
    0.86
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    nuclear periphery
  • C’ GFP library on the background of CCT mutant
    noimage.png
    nuclear periphery
    23.5988
    1.0463
    No