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Elucidating the molecular machinery underlying the development of sexually dimorphic neuronal circuits

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Life Sciences
Sunday, October 17, 2021

How do genes shape neural circuits and animal behaviors? How does a neuronal circuit that controls a sexually dimorphic behavior develop? We aim to understand how sexual dimorphic wiring patterns in the brain develop, from patterning of synapses, to the behavior of the whole organism. Our lab uniquely addresses these questions by using the powerful genetic toolbox of the nematode Caenorhabditis elegans as an in vivo model system. We use diverse cutting-edge techniques such as synapse labeling, neuronal imaging, high-resolution live-imaging microscopy, optogenetics and behavior analysis.