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Our lab studies the organization, function and dysfunction of the prefrontal cortex. The prefrontal cortex is a brain region that plays important roles in many high-order processes, including working memory, emotion regulation, behavioral control, social behaivor and long-term memory.

Problems in prefrontal function are associated with various psychiatric disorders, including major depression, schizophrenia, autism and obsessive-compulsive disorders. Our goal is to understand how this complex circuit operates and to gain a basic understanding of the mechasnisms for its malfunction in disease states.

The Yizhar lab 2017 (photo: O. Yizhar)

We are grateful for the generous support of:

The Ilse Katz Institute for Material Sciences and Magnetic Resonance Research

The Adelis Prize for Brain Research

The Paul and Lucie Schwartz, Georges and Vera Gersen Laboratory

The Candice Appleton Family Trust