Protein Purification

 

The unit specializes in protein purification and characterization for the following purposes:

  • Determination of biological activity
  • Crystallization
  • Study of structure-function relationships and interactions
  • Study of 3D structures
  • Protein engineering and design
  • Raising specific antibodies
  • Development of target-specific drugs
  • Production of therapeutic proteins and vaccines
  • Production of enzymes with biotechnological application
  • Biophysical characterization 

 

The unit provides assistance at the following stages:

  • Design of protein constructs and experimental planning
  • Concentration of large-scale cultures and buffer exchange
  • Protein purification
  • Removal of tags
  • Protein concentration and stabilization
  • Protease treatment of proteins
  • Refolding of proteins
  • Protein characterization