Tzahor Lab

  • Gonzalo del Monte-Nieto; Mirana Ramialison; Arne A. S. Adam; Bingruo Wu; Alla Aharonov; Gabriele D'Uva; Lauren M. Bourke; Mara E. Pitulescu; Hanying Chen; Jose Luis de la Pompa; Weinian Shou; Ralf H. Adams; Sarah K. Harten; Eldad Tzahor; Bin Zhou; Richard P. Harvey (2018). Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.  Nature. 2018 May , 557 (7705):439-+.
  • Tzahor, E; Poss, K (2017). Cardiac regeneration strategies: Staying young at heart..  SCIENCE. 2017, 356 (6342):1035-1039.
  • Elad Bassat; Yara Eid Mutlak; Alex Genzelinakh; Ilya Y. Shadrin; Kfir-Baruch Umansky; Oren Yifa; David Kain; Dana Rajchman; John Leach; Daria Riabov Bassat; Yael Udi; Rachel Sarig; Irit Sagi; James F. Martin; Nenad Bursac; Shenhav Cohen; Eldad Tzahor (2017). The extracellular matrix protein agrin promotes heart regeneration in mice.  Nature. 2017 Jul , 547 (7662):179-+.
  • Lyad Zamir; Ratnakar Singh; Elisha Nathan; R Patrick; Oren Yifa; Y Yahalom-Ronen; A A Arraf; T M Schultheiss; S Suo; JJD Han; G Peng; Naihe Jing; Y Wang; N Palpant; P PL Tam; Richard P Harvey; Eldad Tzahor (2017). Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta.  eLife. 2017 May , .
  • Eldad Tzahor; Kenneth D. Poss (2017). Cardiac regeneration strategies: Staying young at heart.  Science. 2017 Jun , 356 (6342):1035-1039.
  • Eldad Tzahor; Rachel Sarig (2017). The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?.  Carcinogenesis. 2017 Apr , 38 (4):359-366.
  • Haig Aghajanian; Young Kuk Cho; Lauren J. Manderfield; Madison R. Herling; Mudit Gupta; Vivienne C. Ho; Li Li; Karl Degenhardt; Alla Aharonov; Eldad Tzahor; Jonathan A. Epstein (2016). Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor.  Nature Communications. 2016 Jun , 7 .
  • Liat Buzaglo-Azriel; Yael Kuperman; Michael Tsoory; Yehudit Zaltsman; Liat Shachnai; Smadar Levin-Zaidman; Elad Bassat; Inbal Michailovici; Alona Sarver; Eldad Tzahor; Michal Haran; Cecile Vernochet; Atan Gross (2016). Loss Of Muscle Mtch2 Increases Whole-Body Energy Utilization And Protects From Diet-Induced Obesity.  Cell Reports. 2016 Feb , 14 (7):1602-1610.
  • Jussi V. Leinonen; Avishag Korkus-Emanuelov; Yochai Wolf; Michal Milgrom-Hoffman; David Lichtstein; Sara Hoss; Chaim Lotan; Eldad Tzahor; Steffen Jung; Ronen Beeri (2016). Macrophage precursor cells from the left atrial appendage of the heart spontaneously reprogram into a C-kit +/CD45-stem cell-like phenotype.  International Journal of Cardiology. 2016 Apr , 209 :296-306.
  • Inbal Michailovici; Tamar Eigler; Eldad Tzahor (2015). Craniofacial Muscle Development.  CRANIOFACIAL DEVELOPMENT. 2015, :3-30.
  • Dana Rajchman; Rachel Sarig; Benjamin Geiger; Eldad Tzahor; Yfat Yahalom-Ronen (2015). Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion..  eLife. 2015, 4 .
  • Gabriele D'Uva; Alla Aharonov; Mattia Lauriola; David Kain; Yfat Yahalom-Ronen; Silvia Carvalho; Karen Weisinger; Elad Bassat; Dana Rajchman; Oren Yifa; Marina Lysenko; Tal Konfino; Julius Hegesh; Ori Brenner; Michal Neeman; Yosef Yarden; Jonathan Leor; Rachel Sarig; Richard P. Harvey; Eldad Tzahor (2015). ERBB2 triggers mammalian heart regeneration by promoting cardiorlyocyte dedifferentiation and proliferation.  Nature Cell Biology. 2015 May , 17 (5):627-U207.
  • Rui Diogo; Robert G. Kelly; Lionel Christiaen; Michael Levine; Janine M. Ziermann; Julia L. Molnar; Drew M. Noden; Eldad Tzahor (2015). A new heart for a new head in vertebrate cardiopharyngeal evolution.  Nature. 2015 Apr , 520 (7548):466-473.
  • Gabriele D'Uva; Eldad Tzahor (2015). The key roles of ERBB2 in cardiac regeneration.  Cell Cycle. 2015 Aug , 14 (15):2383-2384.
  • Eldad Tzahor (2015). Cardiac and craniofacial development and regeneration.  FASEB Journal. 2015 Apr , 29 .
  • Michal Milgrom-Hoffman; Inbal Michailovici; N Ferrara; Elazar Zelzer; Eldad Tzahor (2014). Endothelial cells regulate neural crest and second heart field morphogenesis.  Biology Open. 2014 Aug , 3 (8):679-688.
  • Inbal Michailovici; Heather A. Harrington; Hadar Hay Azogui; Yfat Yahalom-Ronen; Alexander Plotnikov; Saunders Ching; Michael P. H. Stumpf; Ophir D. Klein; Rony Seger; Eldad Tzahor (2014). Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells.  Development. 2014 Jul , 141 (13):2611-2620.
  • J. Leinonen; A. Korkus-Emanuelov; Michal Milgrom-Hoffman; S. Hoss; C. Lotan; Eldad Tzahor; R. Beeri (2013). Cardiac progenitor cells from the left atrial appendage may originate from a resident non-hematopoietic myeloid progenitor population.  European Heart Journal. 2013 Aug , 34 :280-280.
  • Katrien Vandoorne; Moriel H. Vandsburger; Tal Raz; Moran Shalev; Karen Weisinger; Inbal Biton; Vlad Brumfeld; Calanit Raanan; Nava Nevo; Raya Eilam; Brian A. Hemmings; Eldad Tzahor; Alon Harmelin; Lior Gepstein; Michal Neeman (2013). Chronic Akt1 Deficiency Attenuates Adverse Remodeling and Enhances Angiogenesis After Myocardial Infarction.  Circulation-Cardiovascular Imaging. 2013 Nov , 6 (6):992-1000.
  • Yael Gruenbaum-Cohen; Itamar Harel; Kfir-Baruch Umansky; Eldad Tzahor; Scott B. Snapper; Ben-Zion Shilo; Eyal D. Schejter (2012). The actin regulator N-WASp is required for muscle-cell fusion in mice.  Proceedings of the National Academy of Sciences of the United States of America. 2012 Jul , 109 (28):11211-11216.
  • Itamar Harel; Yoshiro Maezawa; Roi Avraham; Ariel Rinon; Hsiao-Yen Ma; Joe W. Cross; Noam Leviatan; Julius Hegesh; Achira Roy; Jasmine Jacob-Hirsch; Gideon Rechavi; Jaime Carvajal; Shubha Tole; Chrissa Kioussi; Susan Quaggin; Eldad Tzahor (2012). Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis.  Proceedings of the National Academy of Sciences of the United States of America. 2012 Nov , 109 (46):18839-18844.
  • Ariel Rinon; Alina Molchadsky; Elisha Nathan; Gili Yovel; Varda Rotter; Rachel Sarig; Eldad Tzahor (2011). p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes.  Development. 2011 May , 138 (9):1827-1838.
  • Rachel Sarig; Eldad Tzahor (2011). p53 and epithelial-mesenchymal transition A linking thread between embryogenesis and cancer.  Cell Cycle. 2011 Sept , 10 (18):3036-3037.
  • Michal Milgrom-Hoffman; Zachary Harrelson; Napoleone Ferrara; Elazar Zelzer; Sylvia M. Evans; Eldad Tzahor (2011). The heart endocardium is derived from vascular endothelial progenitors.  Development. 2011 Nov , 138 (21):4777-4787.
  • Eldad Tzahor; Sylvia M. Evans (2011). Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis.  Cardiovascular Research. 2011 Jul , 91 (2):196-202.
  • Susanne Theis; Ketan Patel; Petr Valasek; Anthony Otto; Qin Pu; Itamar Harel; Eldad Tzahor; Shahragim Tajbakhsh; Bodo Christ; Ruijin Huang (2010). The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature.  Development. 2010 Sept , 137 (17):2961-2971.
  • Libbat Tirosh-Finkel; Amit Zeisel; Miriam Brodt-Ivenshitz; Ayelet Shamai; Zhong Yao; Rony Seger; Eytan Domany; Eldad Tzahor (2010). BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors.  Development. 2010 Sept , 137 (18):2989-3000.
  • Ariel Rinon; Elisha Nathan; Eldad Tzahor (2009). p53 involvement in early cranial neural crest development in the chick.  Developmental Biology. 2009 Jul , 331 (2):430-430.
  • Elisha Nathan; Eldad Tzahor (2009). sFRPs: a declaration of (Wnt) independence.  Nature Cell Biology. 2009 Jan , 11 (1):13-14.
  • Itamar Harel; Elisha Nathan; Libbat Tirosh-Finkel; Hila Zigdon; Nuno Guimaraes-Camboa; Sylvia M. Evans; Eldad Tzahor (2009). Distinct Origins and Genetic Programs of Head Muscle Satellite Cells.  Developmental Cell. 2009 Jun , 16 (6):822-832.
  • Eldad Tzahor (2009). Heart and craniofacial muscle development: A new developmental theme of distinct myogenic fields.  Developmental Biology. 2009 Mar , 327 (2):273-279.
  • Jeremy Ben-Shoshan; Sofia Maysel-Auslender; Galia Luboshits; Iris Barshack; Sylvie Polak-Charcon; Eldad Tzahor; Gad Keren; Jacob George (2009). Hypoxia-Inducible Factor-1 alpha and-2 alpha Additively Promote Endothelial Vasculogenic Properties.  Journal of Vascular Research. 2009, 46 (4):299-310.
  • Jione Kang; Elisha Nathan; Shan-Mei Xu; Eldad Tzahor; Brian L. Black (2009). Isl1 is a direct transcriptional target of Forkhead transcription factors in second heart field-derived mesoderm.  Developmental Biology. 2009 Oct , 334 (2):513-522.
  • Alina Molchadsky; Igor Shats; Naomi Goldfinger; Meirav Pevsner-Fischer; Melissa Olson; Ariel Rinon; Eldad Tzahor; Guillermina Lozano; Dov Zipori; Rachel Sarig; Varda Rotter (2008). p53 Plays a Role in Mesenchymal Differentiation Programs, in a Cell Fate Dependent Manner.  PLoS One. 2008 Nov , 3 (11).
  • Adam Wasserstrom; Dan Frumkin; Rivka Adar; Shalev Itzkovitz; Tomer Stern; Shai Kaplan; Gabi Shefer; Irena Shur; Lior Zangi; Yitzhak Reizel; Alon Harmelin; Yuval Dor; Nava Dekel; Yair Reisner; Dafna Benayahu; Eldad Tzahor; Eran Segal; Ehud Shapiro (2008). Estimating cell depth from somatic mutations.  PLoS Computational Biology. 2008 May , 4 (5).
  • Jeremy Ben-Shoshan; Shulamit Schwartz; Galia Luboshits; Sofia Maysel-Auslender; Aya Barzelay; Sylvie Polak-Charcon; Iris Barshack; Eldad Tzahor; Adiel Barak; Hani Levkovitch-Verbin; Gad Keren; Jacob George (2008). Constitutive expression of HIF-1 alpha and HIF-2 alpha in bone marrow stromal cells differentially promote their pro-angiogenic properties.  Human Gene Therapy. 2008 Oct , 19 (10):1180-1180.
  • Jeremy Ben-Shoshan; Sofia Maysel-Auslender; Galia Luboshits; Iris Barshack; Sylvie Polak-Charcon; Eldad Tzahor; Gad Keren; Jacob George (2008). Hypoxia inducible factor 1 alpha (HIF-1 alpha) and HIF-2 alpha additively promote endothelial vasculogenic properties.  Human Gene Therapy. 2008 Oct , 19 (10):1111-1111.
  • Jeremy Ben-Shoshan; Shulamit Schwartz; Galia Luboshits; Sofia Maysel-Auslender; Aya Barzelay; Sylvie Polak-Charcon; Eldad Tzahor; Iris Barshack; Adiel Barak; Hani Levkovitch-Verbin; Gad Keren; Jacob George (2008). Constitutive Expression of HIF-1 alpha and HIF-2 alpha in Bone Marrow Stromal Cells Differentially Promotes Their Proangiogenic Properties.  Stem Cells. 2008, 26 (10):2634-2643.
  • Alexandra Klaus; Eldad Tzahor; Walter Birchmeier (2008). Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.  European Journal of Cell Biology. 2008 Jul , 87 (7):435-435.
  • Elisha Nathan; Amir Monovich; Libbat Tirosh-Finkel; Zachary Harrelson; Tal Rousso; Ariel Rinon; Itamar Harel; Sylvia M. Evans; Eldad Tzahor (2008). The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development.  Development. 2008 Feb , 135 (4):647-657.
  • Adam Wasserstrom; Rivka Adar; Gabi Shefer; Dan Frumkin; Shalev Itzkovitz; Tomer Stern; Irena Shur; Lior Zangi; Shai Kaplan; Alon Harmelin; Yair Reisner; Dafna Benayahu; Eldad Tzahor; Eran Segal; Ehud Shapiro (2008). Reconstruction of Cell Lineage Trees in Mice.  PLoS One. 2008 Apr , 3 (4).
  • Ariel Rinon; Shlomi Lazar; Heather Marshall; Stine Buechmann-Moller; Adi Neufeld; Hadas Elhanany-Tamir; Makoto M. Taketo; Lukas Sommer; Robb Krumlauf; Eldad Tzahor (2007). Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis.  Development. 2007 Sept , 134 (17):3065-3075.
  • Eldad Tzahor (2007). Wnt/beta-catenin signaling and cardiogenesis: Timing does matter.  Developmental Cell. 2007 Jul , 13 (1):10-13.
  • Eldad Tzahor (2007). The contribution of second heart field cells to the jaw muscle reveals the multipotential nature of the cardio-craniofacial mesoderm.  Circulation Research. 2007 Aug , 101 (5):E69-E69.
  • Alexandra Klaus; Yumiko Saga; Makoto M. Taketo; Eldad Tzahor; Walter Birchmeier (2007). Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.  Proceedings of the National Academy of Sciences of the United States of America. 2007 Nov , 104 (47):18531-18536.
  • L Tirosh-Finkel; H Elhanany; Ariel Rinon; Eldad Tzahor (2006). Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract.  Development. 2006 May , 133 (10):1943-1953.