Stress Linked Psychopathologies | The neurobiology of stress

January 19, 2026

Mapping the stress response: A high-resolution single-cell atlas of the hippocampus.

Our latest publication in Molecular Psychiatry provides the most comprehensive characterization to date of the adult male hippocampus under stress, identifying cell-type specific molecular signatures.

De Donno C, Lopez JP, D. Luecken M, Kos A, Brivio E, Bordes J, Yang H, M. Deussing J, V. Schmidt M, J. Theis F, Chen A.
Single-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for Nrgn and Sgk1 in response to a social stressor. Mol Psychiatry. doi: 10.1038/s41380-025-03417-y.

Shoshani-Haye K, Friedlander G, Golani O, Almeida-Correa S, Shemesh Y, Chen A.
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities. Neurobiology of Stress. doi: 10.1016/j.ynstr.2025.100749.

Choham Sudre

PhD student

Choham is a neuroscientist investigating how inter-individual variability influences responses to chronic stress and classical antidepressants.

Anpilov S, Shemesh Y, Benjamin A, Biagini T, Umanski D, Zur Y, Sztainberg Y, Richter-Levin A, Forkosh O, Chen A.
Group Social Dynamics in a Seminatural Setup Reflect the Adaptive Value of Aggression in Male Mice. Biological Psychiatry Global Open Science. doi:10.1016/j.bpsgos.2024.100399.

April 28, 2024

Group social dynamics in a semi-natural setup reveal an adaptive value for aggression in male mice.

Environmental enrichment and oxytocin knockout show opposite effect on aggression and hierarchy structure in male mice.

May 8, 2024

Semi-natural setups can contribute to a more complete understanding of dominance and aggression in mice.

Checkout our latest review in Current Opinion in Neurobiology.

Dr. Daniil Umanski

Data specialist

Daniil develops elaborate data analysis, visualization, and real-time activation methods for neuroscience experiments, using machine learning models to predict animal behavior from video analysis.

Shemesh Y, Benjamin A, Shoshani-Haye K, Yizhar O, Chen A.
Studying dominance and aggression requires ethologically relevant paradigms. Current opinion in neurobiology. doi: 10.1016/j.conb.2024.102879.