Stress Circuitry and Regulation

Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PAT, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW.
Urocortin 3 transgenic mice exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high fat diet. Diabetologia 54:2392-2403. [13]

Kuperman Y, Issler O, Vaughan J, Bilezikjian L, Vale W, Chen A.
Expression and regulation of corticotropin-releasing factor receptor type 2β in developing and mature mouse skeletal muscle. Mol Endocrinol. 25:157-169. [10]

Elliott E, Ezra-Nevo G, Regev L, Neufeld-Cohen A, Chen A.
Resilience to social stress coincides with functional DNA methylation of the CRF gene in adult mice. Nat Neurosci. 13:1351-1353. [201]

Neufeld-Cohen A, Tsoory M, Evans AK, Getselter D, Gil S, Lowry CA, Vale W, Chen A.
A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proc Natl Acad Sci USA 107:19020-19025. [51]

Kuperman Y, Issler O, Regev L, Musseri I, Navon I, Neufeld-Cohen A, Gil S, Chen A.
Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis. Proc Natl Acad Sci USA 107:8393-8398. [36]

Neufeld-Cohen A, Evans A, Getselter G, Spyroglou A, Hill A, Gil S, Beuschlein F, Lowry C, Vale W, Chen A.
Urocortin1 and 2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits. Mol. Psychiatry 15:426-441. [44]

Regev L, Ezrielev E, Gershon E, Gil S, Chen A.
Genetic approach for intracerebroventricular delivery. Proc Natl Acad Sci USA 107:4424-4429. [22]

Sztainberg Y, Kuperman Y, Tsoory M, Lebow M, Chen A.
The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1. Mol. Psychiatry 15:905-917. [89]