Naïve CD4 T cells arrest on antigen presenting DCs in vivo independently of DC ICAM-1

Naïve CD4 T cells arrest on antigen presenting DCs in vivo independently of DC ICAM-1

A dsRed labeled OT-II CD4+ cell (red) interacting with an ICAM-1 and 2 double deficient DC (GFP, green) in the T zone of a popliteal lymph node. WT DCs are CFP labeled. Mice were immunized with αDEC-205-OVA and αCD40 mAb. Bar, 10 μm.