Stress fiber bending during T cell TEM

Stress fiber bending by the nucleus of a transmigrating effector T cell crossing transcellularly through inflamed HDMVECs

A time lapse movie depicting a Hoechst labeled effector T cell crossing through a transcellular route of IL-1b-stimulated HDMVECs expressing RFP-Lifeact. Images were taken 20 sec apart. Elapsed time is designated as h:mm:ss. Bar, 5 μm.