2024

Noninvasive Real-Time Glucose Monitoring Is in the Near Future

Hirsch I. B., Tirosh A. & Navon A. (2024) Diabetes Technology and Therapeutics
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Recycled melanoma-secreted melanosomes regulate tumor-associated macrophage diversification

Parikh R., Parikh S., Berzin D., Vaknine H., Ovadia S., Likonen D., Greenberger S., Scope A., Elgavish S., Nevo Y., Plaschkes I., Nizri E., Kobiler O., Maliah A., Zaremba L., Mohan V., Sagi I., Ashery-Padan R., Carmi Y., Luxenburg C., Hoheisel J. D., Khaled M., Levesque M. P. & Levy C. (2024) EMBO Journal
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Competitive fungal commensalism mitigates candidiasis pathology

Sekeresova Kralova J., Donic C., Dassa B., Livyatan I., Jansen P. M., Ben-Dor S., Fidel L., Trzebanski S., Narunsky-Haziza L., Asraf O., Brenner O., Dafni H., Jona G., Boura-Halfon S., Stettner N., Segal E., Brunke S., Pilpel Y., Straussman R., Zeevi D., Bacher P., Hube B., Shlezinger N. & Jung S. (2024) Journal of Experimental Medicine
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Not just Glia—Dissecting brain macrophages in the mouse

Frumer G. R., Shin S. H., Jung S. & Kim J. S. (2024) GLIA
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The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta

Stroganov S., Harris T., Alyagor L., Ben Moyal L., Plitman Mayo R., Golani O., Hirsch D., Ben-Dor S., Brandis A., Mehlman T., Kovo M., Biron-Shental T., Dekel N. & Neeman M. (2024) eLife
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Computational optimization of antibody humanness and stability by systematic energy-based ranking

Tennenhouse A., Khmelnitsky L., Khalaila R., Yeshaya N., Noronha A., Lindzen M., Makowski E. K., Zaretsky I., Sirkis Y. F., Galon-Wolfenson Y., Tessier P. M., Abramson J., Yarden Y., Fass D. & Fleishman S. J. (2024) Nature Biomedical Engineering
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Draft genome of Kazachstania heterogenica var. weizmannii, a commensal fungus of the mouse digestive tract

Sekeresova K. J., Lena F., Catalina D., Shifra B. & Steffen J. (2024) Microbiology Resource Announcements
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The emerging family of RORγt+ antigen-presenting cells

Abramson J., Dobeš J., Lyu M. & Sonnenberg G. F. (2024) Nature Reviews Immunology
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Z-DNA marks the spot for AIRE

Goldfarb Y. & Abramson J. (2024) Cell Research
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Proteolytic Vesicles Derived from Salmonella enterica Serovar Typhimurium-Infected Macrophages: Enhancing MMP-9-Mediated Invasion and EV Accumulation

Nudelman A., Shenoy A., Allouche-Arnon H., Fisler M., Rosenhek-Goldian I., Dayan L., Abou Karam P., Porat Z., Solomonov I., Regev-Rudzki N., Bar-Shir A. & Sagi I. (2024) Biomedicines
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Cancer Hallmarks: Piecing the Puzzle Together

Alcolea M. P., Alonso-Curbelo D., Ambrogio C., Bullman S., Correia A. L., Ernst A., Halbrook C. J., Kelly G. L., Lund A. W., Quail D. F., Ruscetti M., Shema E., Stromnes I. M. & Tam W. L. (2024) Cancer Discovery
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Translatome Profiling of Tissue-Resident Macrophages Using the RiboTag Approach

Kim J. S., Haimon Z., Boura-Halfon S. & Jung S. (2024) , Tissue-Resident Macrophages , Methods and Protocols
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Single-Molecule Fluorescent In Situ Hybridization (smFISH) for RNA Detection in Bacteria

Ciolli Mattioli C. & Avraham R. (2024) , Fluorescence In Situ Hybridization (FISH) , Methods and Protocols
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Tuft cells and fibroblasts promote thymus regeneration through ILC2-mediated type 2 immune response

Nevo S., Frenkel N., Kadouri N., Gome T., Rosenthal N., Givony T., Avin A., Peligero Cruz C., Kedmi M., Lindzen M., Ben Dor S., Damari G., Porat Z., Haffner-Krausz R., Keren-Shaul H., Yarden Y., Munitz A., Leshkowitz D., Goldfarb Y. & Abramson J. (2024) Science Immunology
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Integrated Metabolomics and Proteomics of Symptomatic and Early Presymptomatic States of Colitis

Shimshoni E., Solomonov I., Sagi I. & Ghini V. (2024) Journal of Proteome Research
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Segmented filamentous bacteria-induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover

Brabec T., Schwarzer M., Kováčová K., Dobešová M., Schierová D., Březina J., Pacáková I., Šrůtková D., Ben-Nun O., Goldfarb Y., Šplíchalová I., Kolář M., Abramson J., Filipp D. & Dobeš J. (2024) Journal of Experimental Medicine
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Generation of Non-Alloreactive Antiviral Central Memory CD8 Human Veto T Cells for Cell Therapy

Bachar-Lustig E., Lask A., Eidelstein Y., Or-Geva N., Gidron-Budovsky R., Nathansohn-Levy B., Eyrich M., Liu W. H., Dang G., Miranda K. C., Ramirez A., Kaur I., Rezvani K., Shpall E., Champlin R. E., Nagler A., Shimoni A., Barnees-Kagan S. & Reisner Y. (2024) Transplantation and Cellular Therapy
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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

Trzebanski S., Kim J., Larossi N., Raanan A., Kancheva D., Bastos J., Haddad M., Solomon A., Sivan E., Aizik D., Kralova J. S., Gross-Vered M., Boura-Halfon S., Lapidot T., Alon R., Movahedi K. & Jung S. (2024) Immunity
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The links are still missing: Revisiting the role of RNA as a guide for chromatin-associated proteins

Nielsen M. & Ulitksy I. (2024) Molecular Cell
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Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression

Dunn-Davies H., Dudnakova T., Nogara A., Rodor J., Thomas A. C., Parish E., Gautier P., Meynert A., Ulitsky I., Madeddu P., Caporali A., Baker A., Tollervey D. & Mitić T. (2024) Molecular Therapy Nucleic Acids
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Tackling Tissue Macrophage Heterogeneity by SplitCre Transgenesis

Boura-Halfon S., Haffner-Krausz R., Ben-Dor S., Kim J. S. & Jung S. (2024) , Tissue-Resident Macrophages , Methods and Protocols
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Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis

Nadel G., Yao Z., Hacohen-Lev-Ran A., Wainstein E., Maik-Rachline G., Ziv T., Naor Z., Admon A. & Seger R. (2024) Cell Communication and Signaling
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Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ

Yu Y., Farooq M. S., Eberhart Meessen S., Jiang Y., Kato D., Zhan T., Weiss C., Seger R., Kang W., Zhang X., Yu J., Ebert M. P. & Burgermeister E. (2024) Cell Death and Disease
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Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction

Weidner P., Saar D., Söhn M., Schroeder T., Yu Y., Zöllner F. G., Ponelies N., Zhou X., Zwicky A., Rohrbacher F. N., Pattabiraman V. R., Tanriver M., Bauer A., Ahmed H., Ametamey S. M., Riffel P., Seger R., Bode J. W., Wade R. C., Ebert M. P., Kragelund B. B. & Burgermeister E. (2024) Cancer Letters
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MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion

Goldman A., Mullokandov M., Zaltsman Y., Regev L., Levin-Zaidman S. & Gross A. (2024) EMBO Reports
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Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure

Su M., Fleischer T., Grosheva I., Horev M. B., Olszewska M., Mattioli C. C., Barr H., Plotnikov A., Carvalho S., Moskovich Y., Minden M. D., Chapal-Ilani N., Wainstein A., Papapetrou E. P., Dezorella N., Cheng T., Kaushansky N., Geiger B. & Shlush L. I. (2024) iScience
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2023

The MAPK Signaling Cascades

Maik-Rachline G., Wexler S. & Seger R. (2023) , Encyclopedia of Cell Biology
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Cell Adhesion to the Extracellular Matrix

Geiger B., Livne A. & Grosheva I. (2023) , Encyclopedia of Cell Biology
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PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation

Cohen L. R. Z., Kaffe B., Deri E., Leibson C., Nissim-Rafinia M., Maman M., Harpaz N., Ron G., Shema E. & Meshorer E. (2023) Nucleic Acids Research
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Chiral growth of adherent filopodia

Li W., Chung W. L., Kozlov M. M., Medalia O., Geiger B. & Bershadsky A. D. (2023) Biophysical Journal
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Evolution is driven by natural autoencoding: reframing species, interaction codes, cooperation and sexual reproduction

Cohen I. R. & Marron A. (2023) Proceedings of the Royal Society B: Biological Sciences
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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

Rosenberg M. I., Greenstein E., Buchkovich M., Peres A., Santoni-Rugiu E., Yang L., Mikl M., Vaksman Z., Gibbs D. L., Reshef D., Salovin A., Irwin M. S., Naranjo A., Ulitsky I., de Alarcon P. A., Matthay K. K., Weigman V., Yaari G., Panzer J. A., Friedman N. & Maris J. M. (2023) Cell Reports
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Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets

Beumers L., Vlachavas E. I., Borgoni S., Schwarzmüller L., Penso-Dolfin L., Michels B. E., Sofyali E., Burmester S., Heiss D., Wilhelm H., Yarden Y., Helm D., Will R., Goncalves A. & Wiemann S. (2023) NPJ Breast Cancer
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Paired single-cell host profiling with multiplex-tagged bacterial mutants reveals intracellular virulence-immune networks

Heyman O., Yehezkel D., Ciolli Mattioli C., Blumberger N., Rosenberg G., Solomon A., Hoffman D., Bossel Ben-Moshe N. & Avraham R. (2023) Proceedings of the National Academy of Sciences
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Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Vidakovic L., Mikhaleva S., Jeckel H., Nisnevich V., Strenger K., Neuhaus K., Raveendran K., Ben-Moshe N. B., Aznaourova M., Nosho K., Drescher A., Schmeck B., Schulte L. N., Persat A., Avraham R. & Drescher K. (2023) Cell
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Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria

Michailov Y., Nemerovsky L., Ghetler Y., Finkelstein M., Schonberger O., Wiser A., Raziel A., Saar-Ryss B., Ben-Ami I., Kaplanski O., Miller N., Haikin Herzberger E., Mashiach Friedler Y., Levitas-Djerbi T., Amsalem E., Umanski N., Tamadaev V., Ovadia Y. S., Peretz A., Sacks G., Dekel N., Zaken O. & Levi M. (2023) Biomedicines
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Quantification of Invadopodia Formation and Matrix Degradation Activity

Venghateri J. B. & Geiger B. (2023) , Methods in Molecular Biology
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Silc1 long noncoding RNA is an immediate-early gene promoting efficient memory formation

Ben-Tov Perry R., Tsoory M., Tolmasov M. & Ulitsky I. (2023) Cell Reports
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Bacterial lifestyle switch in response to algal metabolites

Barak-Gavish N., Dassa B., Kuhlisch C., Nussbaum I., Brandis A., Rosenberg G., Avraham R. & Vardi A. (2023) eLife
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Protein Orientation Defines Rectification of Electronic Current via Solid-State Junction of Entire Photosystem‑1 Complex

Fereiro J. A., Bendikov T., Herrmann A., Pecht I., Sheves M. & Cahen D. (2023) Journal of Physical Chemistry Letters
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Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis

Zioni N., Bercovich A. A., Chapal-Ilani N., Bacharach T., Rappoport N., Solomon A., Avraham R., Kopitman E., Porat Z., Sacma M., Hartmut G., Scheller M., Muller-Tidow C., Lipka D., Shlush E., Minden M., Kaushansky N. & Shlush L. I. (2023) Nature Communications
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Distinct spatiotemporal features of microglia and monocyte-derived macrophages in glioma

Banerjee K., Ratzabi A., Caspit I. M., Ganon O., Blinder P., Jung S. & Stein R. (2023) European Journal of Immunology
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L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

Marrocco I., Giri S., Simoni-Nieves A., Gupta N., Rudnitsky A., Haga Y., Romaniello D., Sekar A., Zerbib M., Oren R., Lindzen M., Fard D., Tsutsumi Y., Lauriola M., Tamagnone L. & Yarden Y. (2023) Cell Reports Medicine
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Allosteric activation of vinculin by talin

Franz F., Tapia-Rojo R., Winograd-Katz S., Boujemaa-Paterski R., Li W., Unger T., Albeck S., Aponte-Santamaria C., Garcia-Manyes S., Medalia O., Geiger B. & Gräter F. (2023) Nature Communications
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A partial form of AIRE deficiency underlies a mild form of autoimmune polyendocrine syndrome type 1

Oftedal B. E., Berger A. H., Bruserud Ø., Goldfarb Y., Sulen A., Breivik L., Hellesen A., Ben-Dor S., Haffner-Krausz R., Knappskog P. M., Johansson S., Wolff A. S., Bratland E., Abramson J. & Husebye E. S. (2023) The Journal of Clinical Investigation
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Vaccinations in pregnancy against TORCH pathogens

Beharier O. & Neeman M. (2023) Molecular Therapy
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Retention of ERK in the cytoplasm mediates the pluripotency of embryonic stem cells

Hacohen Lev-Ran A. & Seger R. (2023) Stem Cell Reports
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Redefining metalloproteases specificity through network proteolysis

Kollet O., Das A., Karamanos N., auf dem Keller U. & Sagi I. (2023) Trends in Molecular Medicine
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JNK Cascade-Induced Apoptosis—A Unique Role in GqPCR Signaling

Nadel G., Maik-Rachline G. & Seger R. (2023) International Journal of Molecular Sciences
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Long non-coding RNAs: definitions, functions, challenges and recommendations

Mattick J. S., Amaral P. P., Carninci P., Carpenter S., Chang H. Y., Chen L., Chen R., Dean C., Dinger M. E., Fitzgerald K. A., Gingeras T. R., Guttman M., Hirose T., Huarte M., Johnson R., Kanduri C., Kapranov P., Lawrence J. B., Lee J. T., Mendell J. T., Mercer T. R., Moore K. J., Nakagawa S., Rinn J. L., Spector D. L., Ulitsky I., Wan Y., Wilusz J. E. & Wu M. (2023) Nature Reviews Molecular Cell Biology
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Noncoding snoRNA host genes are a distinct subclass of long noncoding RNAs

Monziani A. & Ulitsky I. (2023) Trends in Genetics
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Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

Gil N., Perry R. B., Mukamel Z., Tuck A., Bühler M. & Ulitsky I. (2023) Cell Reports
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CENTRE: a gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction

Rapakoulia T., Lopez De Vargas S. R., Omgba P. A., Laupert V., Ulitsky I. & Vingron M. (2023) Bioinformatics
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Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

Weeks E. M., Ulirsch J. C., Cheng N. Y., Trippe B. L., Fine R. S., Miao J., Patwardhan T. A., Kanai M., Nasser J., Fulco C. P., Tashman K. C., Aguet F., Li T., Ordovas-Montanes J., Smillie C. S., Biton M., Shalek A. K., Ananthakrishnan A. N., Xavier R. J., Regev A., Gupta R. M., Lage K., Ardlie K. G., Hirschhorn J. N., Lander E. S., Engreitz J. M. & Finucane H. K. (2023) Nature Genetics
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Glycation-driven matrix crosslinking in cirrhosis

Kollet O. & Sagi I. (2023) Nature Biomedical Engineering
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Timing and regulation of hematopoietic stem cell colonization of the human fetal bone marrow by endothelial and CAR stromal cells during pregnancy

Lapidot T. (2023) Blood Science
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Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics

Fedyuk V., Erez N., Furth N., Beresh O., Andreishcheva E. N., Shinde A., Jones D., Bar Zakai B., Mavor Y., Peretz T., Hubert A., Cohen J., Salah A., Temper M., Grinshpun A., Maoz M., Zick A., Ron G. & Shema E. (2023) Nature Biotechnology
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miR-4734 conditionally suppresses ER stress-associated proinflammatory responses

Michael D., Feldmesser E., Gonen C., Furth N., Maman A., Heyman O., Argoetti A., Tofield A., Baichman-Kass A., Ben-Dov A., Benbenisti D., Hen N., Rotkopf R., Ganci F., Blandino G., Ulitsky I. & Oren M. (2023) FEBS Letters
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Longitudinal in vivo imaging of perineuronal nets

Benbenishty A., Peled-Hajaj S., Krishnaswamy V. R., Har-Gil H., Havusha-Laufer S., Ruggiero A., Slutsky I., Blinder P. & Sagi I. (2023) Neurophotonics
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Tissue-specific macrophage immunometabolism

Ben-Arosh H. & Avraham R. (2023) Current Opinion in Immunology
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Endolysosomal dysfunction in radial glia progenitor cells leads to defective cerebral angiogenesis and compromised Blood-Brain Barrier integrity

Bassi I., Grunspan M., Hen G., Ravichandran K. A., Moshe N., Safriel S. R., Chen A., Almodovar C. R. d. & Yaniv K. (2023) BioRxiv
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Resistance of Lung Cancer to EGFR-Specific Kinase Inhibitors: Activation of Bypass Pathways and Endogenous Mutators

Marrocco I. & Yarden Y. (2023) Cancers
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LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

Kshirsagar A., Doroshev S. M., Gorelik A., Olender T., Sapir T., Tsuboi D., Rosenhek-Goldian I., Malitsky S., Itkin M., Argoetti A., Mandel-Gutfreund Y., Cohen S. R., Hanna J. H., Ulitsky I., Kaibuchi K. & Reiner O. (2023) Nature Communications
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The role of RNF149 in the pre-emptive quality control substrate ubiquitination

Legesse A., Kaushansky N., Braunstein I., Saad H., Lederkremer G., Navon A. & Stanhill A. (2023) Communications Biology
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Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress

Livneh I., Cohen-Kaplan V., Fabre B., Abramovitch I., Lulu C., Nataraj N. B., Lazar I., Ziv T., Yarden Y., Zohar Y., Gottlieb E. & Ciechanover A. (2023) Molecular Cell
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GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis

Sosnovski K. E., Braun T., Amir A., Moshel D., BenShoshan M., VanDussen K. L., Levhar N., Abbas-Egbariya H., Beider K., Ben-Yishay R., Asad Ali S., Moore S. R., Kugathasan S., Abramovich I., Saar E. G., Weiss B., Barshack I., Gottlieb E., Geiger T., Ben-Horin S., Ulitsky I., Hyams J. S., Denson L. A. & Haberman Y. (2023) Journal of Crohn's and Colitis
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Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion

Stark M., Levin M., Ulitsky I. & Assaraf Y. G. (2023) BMC Biology
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Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease

Gruper Y., Wolff A. S. B., Glanz L., Spoutil F., Marthinussen M. C., Osickova A., Herzig Y., Goldfarb Y., Aranaz-Novaliches G., Dobeš J., Kadouri N., Ben-Nun O., Binyamin A., Lavi B., Givony T., Khalaila R., Gome T., Wald T., Mrazkova B., Sochen C., Besnard M., Ben-Dor S., Feldmesser E., Orlova E. M., Hegedűs C., Lampé I., Papp T., Felszeghy S., Sedlacek R., Davidovich E., Tal N., Shouval D. S., Shamir R., Guillonneau C., Szondy Z., Lundin K. E. A., Osicka R., Prochazka J., Husebye E. S. & Abramson J. (2023) Nature
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Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation and matrix degradation

Venghateri J. B., Dassa B., Morgenstern D., Shreberk-Shaked M., Oren M. & Geiger B. (2023) Cell Death & Disease
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Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition

Lax E., Do Carmo S., Enuka Y., Sapozhnikov D. M., Welikovitch L. A., Mahmood N., Rabbani S. A., Wang L., Britt J. P., Hancock W. W., Yarden Y. & Szyf M. (2023) Translational Psychiatry
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Untangling Cellular Host-Pathogen Encounters at Infection Bottlenecks

Avraham R. (2023) Infection and Immunity
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The ERK Signaling Cascade Inhibits Gonadotropin-Stimulated Steroidogenesis

Seger R., Hanoch T., Rosenberg R., Dantes A., Merz W. E., Strauss J. F. & Amsterdam A. (2023) Journal of Biotechnology and Biomedicine
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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease

Braun T., Sosnovski K. E., Amir A., BenShoshan M., VanDussen K. L., Karns R., Levhar N., Abbas-Egbariya H., Hadar R., Efroni G., Castel D., Avivi C., Rosen M. J., Grifiths A. M., Walters T. D., Mack D. R., Boyle B. M., Ali S. A., Moore S. R., Schirmer M., Xavier R. J., Kugathasan S., Jegga A. G., Weiss B., Mayer C., Barshack I., Ben-Horin S., Ulitsky I., Beucher A., Ferrer J., Hyams J. S., Denson L. A. & Haberman Y. (2023) JCI Insight
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Near-Temperature-Independent Electron Transport Well beyond Expected Quantum Tunneling Range via Bacteriorhodopsin Multilayers

Bera S., Fereiro J. A., Saxena S. K., Chryssikos D., Majhi K., Bendikov T., Sepunaru L., Ehre D., Tornow M., Pecht I., Vilan A., Sheves M. & Cahen D. (2023) Journal of the American Chemical Society
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ICAMs are dispensable for influenza clearance and anti-viral humoral and cellular immunity

Kozlovski S., Regev O., Sapoznikov A., Kizner M., Achdout H., Petrovich-Kopitman E., Elkahal J., Addadi Y., Castanheira F. V. E. S., Feigelson S. W., Kubes P., Erez N., Garbi N. & Alon R. (2023) Frontiers in Immunology
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Massively parallel identification of mRNA localization elements in primary cortical neurons

Mendonsa S., von Kügelgen N., Dantsuji S., Ron M., Breimann L., Baranovskii A., Lödige I., Kirchner M., Fischer M., Zerna N., Bujanic L., Mertins P., Ulitsky I. & Chekulaeva M. (2023) Nature Neuroscience
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Thymic mimetic cells function beyond self-tolerance

Givony T., Leshkowitz D., Del Castillo D., Nevo S., Kadouri N., Dassa B., Gruper Y., Khalaila R., Ben-Nun O., Gome T., Dobeš J., Ben-Dor S., Kedmi M., Keren-Shaul H., Heffner-Krausz R., Porat Z., Golani O., Addadi Y., Brenner O., Lo D. D., Goldfarb Y. & Abramson J. (2023) Nature
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Correction of T-Cell Repertoire and Autoimmune Diabetes in NOD Mice by Non-myeloablative T-Cell Depleted Allogeneic HSCT

Sidlik Muskatel R., Nathansohn-Levi B., Reich-Zeliger S., Mark M., Stoler-Barak L., Rosen C., Milman-Krentsis I., Bachar Lustig E., Pete Gale R., Friedman N. & Reisner Y. (2023) Stem Cells Translational Medicine
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TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment

Gershoni A., Hassin O., Nataraj N. B., Baruch S., Avioz-Seligman A., Pirona A. C., Fellus-Alyagor L., Meir Salame T., Mukherjee S., Mallel G., Yarden Y., Aylon Y. & Oren M. (2023) Molecular Oncology
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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

Sapoznikov A., Kozlovski S., Levi N., Feigelson S. W., Regev O., Davidzohn N., Ben-Dor S., Haffner-Krausz R., Feldmesser E., Wigoda N., Petrovich-Kopitman E., Biton M. & Alon R. (2023) Cell Reports
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A single-molecule liquid biopsy for cancer diagnosis

Shema E. (2023) Nature Reviews Cancer
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Boosting maternal and neonatal anti–SARS-CoV-2 humoral immunity using a third mRNA vaccine dose

Cahen-Peretz A., Tsaitlin-Mor L., Kam H. A., Frenkel R., Kabessa M., Cohen S. M., Lipschuetz M., Oiknine-Djian E., Lianski S., Goldman-Wohl D., Walfisch A., Kovo M., Neeman M., Wolf D. G., Yagel S. & Beharier O. (2023) JCI Insight
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Biotin Binding Hardly Affects Electron Transport Efficiency across Streptavidin Solid-State Junctions

Bera S., Govinda S., Fereiro J. A., Pecht I., Sheves M. & Cahen D. (2023) Langmuir
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Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis

Goldman O., Adler L. N., Hajaj E., Croese T., Darzi N., Galai S., Tishler H., Ariav Y., Lavie D., Fellus-Alyagor L., Oren R., Kuznetsov Y., David E., Jaschek R., Stossel C., Singer O., Malitsky S., Barak R., Seger R., Erez N., Amit I., Tanay A., Saada A., Golan T., Rubinek T., Sang Lee J., Ben-Shachar S., Wolf I. & Erez A. (2023) Cancer Discovery
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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

De Schepper S., Ge J. Z., Crowley G., Ferreira L. S. S., Garceau D., Toomey C. E., Sokolova D., Rueda-Carrasco J., Shin S. H., Kim J., Childs T., Lashley T., Burden J. J., Sasner M., Frigerio C. S., Jung S. & Hong S. (2023) Nature Neuroscience
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Multisite assessment of reproducibility in high-content cell migration imaging data

Hu J., Serra-Picamal X., Bakker G. J., Van Troys M., Winograd-Katz S., Ege N., Gong X., Didan Y., Grosheva I., Polansky O., Bakkali K., Van Hamme E., van Erp M., Vullings M., Weiss F., Clucas J., Dowbaj A. M., Sahai E., Ampe C., Geiger B., Friedl P., Bottai M. & Strömblad S. (2023) Molecular Systems Biology
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Lactate—a new player in G-CSF-induced mobilization of hematopoietic stem/progenitor cells

Ordonez-Moreno L. A., Haddad M., Chakrabarti P., Khatib-Massalha E., Fruchtman H., Boura-Halfon S., Petrovich-Kopitman E., Lapidot T. & Kollet O. (2023) Leukemia
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PREPARATION AND EVALUATION OF OOCYTES FOR INTRACYTOPLASMIC SPERM INJECTION

Granot I. & Dekel N. (2023) , Textbook of Assisted Reproductive Techniques , Volume 1: Laboratory Perspectives, Sixth Edition
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Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma

Hedegger K., Blutke A., Hommel T., Auer K. E., Nataraj N. B., Lindzen M., Yarden Y. & Dahlhoff M. (2023) Molecular Oncology
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The Actin Network Interfacing Diverse Integrin-Mediated Adhesions

Geiger B., Boujemaa-Paterski R., Winograd-Katz S. E., Balan Venghateri J., Chung W. L. & Medalia O. (2023) Biomolecules
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Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors

Kacen A., Javitt A., Kramer M. P., Morgenstern D., Tsaban T., Shmueli M. D., Teo G. C., Leprevost F. d. V., Barnea E., Yu F., Admon A., Eisenbach L., Samuels Y., Schueler-Furman O., Levin Y., Nesvizhskii A. & Merbl Y. (2023) Nature Biotechnology
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Amyloid Precursor Protein and Tau Peptides Linked Together Ameliorate Loss of Cognition in an Alzheimer’s Disease Animal Model

Maron R., Vinik Y., Tsoory M., Wilchek M. & Arnon R. (2023) International Journal of Molecular Sciences
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Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

Yunger S., Geiger B., Friedman N., Besser M. J. & Adutler-Lieber S. (2023) Frontiers in Oncology
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Physiological stress drives the emergence of a Salmonella subpopulation through ribosomal RNA regulation

Ciolli Mattioli C., Eisner K., Rosenbaum A., Wang M., Amir A., Golding I. & Avraham R. (2023) Current Biology
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2022

Unique features of transcription termination and initiation at closely spaced tandem human genes

Nissani N. & Ulitsky I. (2022) Molecular Systems Biology
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Cap-independent translation and a precisely located RNA sequence enable SARS-CoV-2 to control host translation and escape anti-viral response

Slobodin B., Sehrawat U., Lev A., Hayat D., Zuckerman B., Fraticelli D., Ogran A., Ben-Shmuel A., Bar-David E., Levy H., Ulitsky I. & Dikstein R. (2022) Nucleic Acids Research
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ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells

Regev O., Kizner M., Roncato F., Dadiani M., Saini M., Castro-Giner F., Yajuk O., Kozlovski S., Levi N., Addadi Y., Golani O., Ben-Dor S., Granot Z., Aceto N. & Alon R. (2022) Frontiers in Immunology
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AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope

Wainstein E., Maik-Rachline G., Blenis J. & Seger R. (2022) Cell Reports
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Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

Mazor R. D., Nathan N., Gilboa A., Stoler-Barak L., Moss L., Solomonov I., Hanuna A., Divinsky Y., Shmueli M. D., Hezroni H., Zaretsky I., Mor M., Golani O., Sabah G., Jakobson-Setton A., Yanichkin N., Feinmesser M., Tsoref D., Salman L., Yeoshoua E., Peretz E., Erlich I., Mendelson Cohen N., Gershoni J. M., Freund N., Merbl Y., Yaari G., Eitan R., Sagi I. & Shulman Z. (2022) Cell
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Microglia states and nomenclature: A field at its crossroads

Paolicelli R. C., Sierra A., Stevens B., Tremblay M., Aguzzi A., Ajami B., Amit I., Audinat E., Bechmann I., Bennett M., Bennett F., Bessis A., Biber K., Bilbo S., Blurton-Jones M., Boddeke E., Brites D., Brône B., Brown G. C., Butovsky O., Carson M. J., Castellano B., Colonna M., Cowley S. A., Cunningham C., Davalos D., De Jager P. L., de Strooper B., Denes A., Eggen B. J., Eyo U., Galea E., Garel S., Ginhoux F., Glass C. K., Gokce O., Gomez-Nicola D., González B., Gordon S., Graeber M. B., Greenhalgh A. D., Gressens P., Greter M., Gutmann D. H., Haass C., Heneka M. T., Heppner F. L., Hong S., Hume D. A., Jung S., Kettenmann H., Kipnis J., Koyama R., Lemke G., Lynch M., Majewska A., Malcangio M., Malm T., Mancuso R., Masuda T., Matteoli M., McColl B. W., Miron V. E., Molofsky A. V., Monje M., Mracsko E., Nadjar A., Neher J. J., Neniskyte U., Neumann H., Noda M., Peng B., Peri F., Perry V. H., Popovich P. G., Pridans C., Priller J., Prinz M., Ragozzino D., Ransohoff R. M., Salter M. W., Schaefer A., Schafer D. P., Schwartz M., Simons M., Smith C. J., Streit W. J., Tay T. L., Tsai L., Verkhratsky A., von Bernhardi R., Wake H., Wittamer V., Wolf S. A., Wu L. & Wyss-Coray T. (2022) Neuron
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ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK

Yung Y., Yao Z., Hanoch T. & Seger R. (2022) Cell Biology International
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A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells

Hammer L., Levin-Salomon V., Yaeli-Slonim N., Weiss M., Dekel-Bird N. P., Olender T., Porat Z., Winograd-Katz S., Savidor A., Levin Y., Bialik S., Geiger B. & Kimchi A. (2022) Molecular Oncology
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Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors

Belugali Nataraj N., Noronha A., Lee J. S., Ghosh S., Mohan Raju H. R., Sekar A., Zuckerman B., Lindzen M., Tarcitano E., Srivastava S., Selitrennik M., Livneh I., Drago-Garcia D., Rueda O. M., Caldas C., Lev S., Geiger T., Ciechanover A., Ulitsky I., Seger R., Ruppin E. & Yarden Y. (2022) Cell Reports
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Tongue immune compartment analysis reveals spatial macrophage heterogeneity

Lyras E. M., Zimmermann K., Wagner L. K., Dorr D., Klose C. S., Fischer C., Jung S., Yona S., Hovav A., Stenzel W., Dommerich S., Conrad T., Leutz A. & Mildner A. (2022) eLife
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Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis

Aylon Y., Furth N., Mallel G., Friedlander G., Nataraj N. B., Dong M., Hassin O., Zoabi R., Cohen B., Drendel V., Salame T. M., Mukherjee S., Harpaz N., Johnson R., Aulitzky W. E., Yarden Y., Shema E. & Oren M. (2022) Nature Communications
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Immunometabolic crosstalk during bacterial infection

Rosenberg G., Riquelme S., Prince A. & Avraham R. (2022) Nature Microbiology
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Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients

Stern S., Lau S., Manole A., Rosh I., Percia M. M., Ben Ezer R., Shokhirev M. N., Qiu F., Schafer S., Mansour A. A., Mangan K. P., Stern T., Ofer P., Stern Y., Mendes A. P. D., Djamus J., Moore L. R., Nayak R., Aicher A., Havusha-Laufer S., Rhee A., Wong T. L., Nguyen T., Linker S. B., Winner B., Freitas B. C., Jones E., Sagi I., Bardy C., Brice A., Winkler J., Marchetto M. C. & Gage F. H. (2022) NPJ Parkinson's Disease
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Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology

Haimon Z., Frumer G. R., Kim J., Trzebanski S., Haffner-Krausz R., Ben-Dor S., Porat Z., Muschaweckh A., Chappell-Maor L., Boura-Halfon S., Korn T. & Jung S. (2022) Nature Immunology
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Extrathymic expression of Aire controls the induction of effective TH17 cell-mediated immune response to Candida albicans

Dobeš J., Ben-Nun O., Binyamin A., Stoler-Barak L., Oftedal B. E., Goldfarb Y., Kadouri N., Gruper Y., Givony T., Zalayat I., Kováčová K., Böhmová H., Valter E., Shulman Z., Filipp D., Husebye E. S. & Abramson J. (2022) Nature Immunology
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Role of Helical Structure in MBP Immunodominant Peptides for Efficient IgM Antibody Recognition in Multiple Sclerosis

Staśkiewicz A., Quagliata M., Real-Fernandez F., Nuti F., Lanzillo R., Brescia-Morra V., Rusche H., Jewginski M., Carotenuto A., Brancaccio D., Aharoni R., Arnon R., Rovero P., Latajka R. & Papini A. M. (2022) Frontiers in Chemistry
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GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch

Nadel G., Yao Z., Wainstein E., Cohen I., Ben-Ami I., Schajnovitz A., Maik-Rachline G., Naor Z., Horwitz B. A. & Seger R. (2022) Cell Communication and Signaling
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Generation of specialized blood vessels via lymphatic transdifferentiation

Das R. N., Tevet Y., Safriel S., Han Y., Moshe N., Lambiase G., Bassi I., Nicenboim J., Brückner M., Hirsch D., Eilam-Altstadter R., Herzog W., Avraham R., Poss K. D. & Yaniv K. (2022) Nature
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Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear

Royer M., Pai B., Menon R., Bludau A., Gryksa K., Perry R. B., Ulitsky I., Meister G. & Neumann I. D. (2022) Molecular Psychiatry
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Dissecting Human Blood Immune Cells Response to Intracellular Infection Using Single-Cell RNA Sequencing

Hen-Avivi S. & Avraham R. (2022) , Methods in Molecular Biology
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Electron transport via tyrosine-doped oligo-alanine peptide junctions: role of charges and hydrogen bonding

Guo C., Gavrilov Y., Gupta S., Bendikov T., Levy Y., Vilan A., Pecht I., Sheves M. & Cahen D. (2022) Physical Chemistry Chemical Physics
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LGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma

Gur C., Wang S., Sheban F., Zada M., Li B., Kharouf F., Peleg H., Aamar S., Yalin A., Kirschenbaum D., Braun-Moscovici Y., Jaitin D. A., Meir-Salame T., Hagai E., Kragesteen B. K., Avni B., Grisariu S., Bornstein C., Shlomi-Loubaton S., David E., Shreberk-Hassidim R., Molho-Pessach V., Amar D., Tzur T., Kuint R., Gross M., Barboy O., Moshe A., Fellus-Alyagor L., Hirsch D., Addadi Y., Erenfeld S., Biton M., Tzemach T., Elazary A., Naparstek Y., Tzemach R., Weiner A., Giladi A., Balbir-Gurman A. & Amit I. (2022) Cell
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Applying imaging flow cytometry and immunofluorescence in studying the dynamic Golgi structure in cultured cells

Wortzel I., Porat Z., Seger R. & Maik-Rachline G. (2022) STAR Protocols
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Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies

Bergado-Báez G., Gonzalez Suarez N., García L. C., Pérez-Martínez D., Hernández-Fernández D. R., Fundora-Barrios T., Rodríguez-Álvarez A., Díaz-Ordaz G. D., Lindzen M., Yarden Y. & Sánchez-Ramírez B. (2022) Frontiers in Oncology
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H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape

Furth N., Algranati D., Dassa B., Beresh O., Fedyuk V., Morris N., Kasper L. H., Jones D., Monje M., Baker S. J. & Shema E. (2022) Cell Reports
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The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

Heinlein M., Gandolfo L. C., Zhao K., Teh C. E., Nguyen N., Baell J. B., Goldfarb Y., Abramson J., Wichmann J., Voss A. K., Strasser A., Smyth G. K., Thomas T. & Gray D. H. D. (2022) Science Immunology
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Substoichiometric action of long noncoding RNAs

Unfried J. P. & Ulitsky I. (2022) Nature Cell Biology
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It's all in the combination: decoding the epigenome for cancer research and diagnostics

Furth N. & Shema E. (2022) Current Opinion in Genetics and Development
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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

Harpaz N., Mittelman T., Beresh O., Griess O., Furth N., Salame T., Oren R., Fellus-Alyagor L., Harmelin A., Alexandrescu S., Marques J. G., Filbin M. G., Ron G. & Shema E. (2022) Molecular Cell
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How many fish make a mouse?

Tzahor E. & Yaniv K. (2022) Nature Cardiovascular Research
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Intracellular peptides as drug prototypes

Gewehr M. C., Navon A. & Ferro E. S. (2022) , Peptide and Peptidomimetic Therapeutics , From Bench to Bedside
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OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency

Bernard L. D., Dubois A., Heurtier V., Fischer V., Gonzalez I., Chervova A., Tachtsidi A., Gil N., Owens N., Bates L. E., Vandormael-Pournin S., Silva J. C. R., Ulitsky I., Cohen-Tannoudji M. & Navarro P. (2022) Nucleic Acids Research
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On the development of a neoantigen vaccine for the prevention of Lynch Syndrome

Solomon A., Alteber Z., Bassan D., Sharbi-Yunger A., Esbit S., Tzehoval E. & Eisenbach L. (2022) International Journal of Cancer
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5’isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1

Li X., Michels B. E., Tosun O. E., Jung J., Kappes J., Ibing S., Nataraj N. B., Sahay S., Schneider M., Wörner A., Becki C., Ishaque N., Feuerbach L., Heßling B., Helm D., Will R., Yarden Y., Müller-Decker K., Wiemann S. & Körner C. (2022) Journal of Experimental and Clinical Cancer Research
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Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins

Mukherjee S., Maddalena M., Lü Y., Martinez S., Nataraj N. B., Noronha A., Sinha S., Teng K., Cohen-Kaplan V., Ziv T., Arandkar S., Hassin O., Chatterjee R., Pirona A., Shreberk-Shaked M., Gershoni A., Aylon Y., Elazar Z., Yarden Y., Schramek D. & Oren M. (2022) Proceedings of the National Academy of Sciences
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Nuclear localization of Meg3-ex10 in mice lateral septum after social fear extinction

Royer M., Pai B., Menon R., Bludau A., Gryksa K., Perry R. B. T., Ulitsky I., Meister G. & Neumann I. D. (2022) Molecular Psychiatry
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Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs

Tarazi S., Aguilera Castrejon A., Joubran C., Ghanem N., Ashouokhi S., Roncato F., Wildschutz E., Haddad M., Oldak B., Gomez-Cesar E., Livnat N., Viukov S., Lukshtanov D., Naveh Tassa S., Rose M., Issaq - Hanna S., Raanan C., Brenner O. J., Kedmi M., Keren-Shaul H., Lapidot T., Maza I., Novershtern N. & Hanna J. (. (2022) Cell
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Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation

Stakenborg M., Abdurahiman S., De Simone V., Goverse G., Stakenborg N., van Baarle L., Wu Q., Pirottin D., Kim J., Chappell-Maor L., Pintelon I., Thys S., Pollenus E., Boon L., Van den Steen P., Hao M., Van Ginderachter J. A., Boeckxstaens G. E., Timmermans J., Jung S., Marichal T., Ibiza S. & Matteoli G. (2022) Mucosal Immunology
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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

Sheban D., Shani T., Maor R., Aguilera-Castrejon A., Mor N., Oldak B., Shmueli M. D., Eisenberg-Lerner A., Bayerl J., Hebert J., Viukov S., Chen G., Kacen A., Krupalnik V., Chugaeva V., Tarazi S., Rodríguez-delaRosa A., Zerbib M., Ulman A., Masarwi S., Kupervaser M., Levin Y., Shema E., David Y., Novershtern N., Hanna J. H. & Merbl Y. (2022) Molecular Cell
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Boosting maternal and neonatal humoral immunity following SARS-CoV-2 infection using a single mRNA vaccine dose

Nevo L., Cahen-Peretz A., Vorontsov O., Frenkel R., Kabessa M., Cohen S. M., Hamrani A., Oiknine-Djian E., Lipschuetz M., Goldman-Wohl D., Walfisch A., Kovo M., Neeman M., Yagel S., Wolf D. G. & Beharier O. (2022) American Journal of Obstetrics and Gynecology
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Prof. Michael Sela (1924-2022) Obituary

Arnon R., Mozes E., Jung S. & Pecht I. (2022) European Journal of Immunology
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Discovering functional motifs in long noncoding RNAs

Ross C. J. & Ulitsky I. (2022) Wiley Interdisciplinary Reviews: RNA
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Real-time single-molecule sequencing of nucleosomal DNA and combinatory histone modifications detection with zero-mode waveguides

Zheng P., Wanunu M. & Shema E. (2022) Biophysical Journal
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Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation

Biram A., Liu J., Hezroni-Bravyi H., Davidzohn N., Schmiedel D., Khatib-Massalha E., Haddad M., Grenov C. A., Lebon S., Salame T. M., Dezorella N., Hoffman D., Abou Karam P., Biton M., Lapidot T., Bemark M., Avraham R., Jung S. & Shulman Z. (2022) Immunity
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The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation

Ma V. P., Hu Y., Kellner A. V., Brockman J. M., Velusamy A., Blanchard A. T., Evavold B. D., Alon R. & Salaita K. (2022) Science Advances
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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients

Hassin O., Nataraj N. B., Shreberk-Shaked M., Aylon Y., Yaeger R., Fontemaggi G., Mukherjee S., Maddalena M., Avioz A., Iancu O., Mallel G., Gershoni A., Grosheva I., Feldmesser E., Ben-Dor S., Golani O., Hendel A., Blandino G., Kelsen D., Yarden Y. & Oren M. (2022) Nature Communications
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Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs

Ron M. & Ulitsky I. (2022) Nature Communications
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Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation

Gindi N., Grossman H., Bar-Joseph H., Miller I., Nemerovsky L., Hadas R., Nevo N., Galiani D., Dekel N. & Shalgi R. (2022) Cell Cycle
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AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Noronha A., Belugali Nataraj N., Sang Lee J., Zhitomirsky B., Oren Y., Oster S., Lindzen M., Mukherjee S., Will R., Ghosh S., Simoni-Nieves A., Verma A., Chatterjee R., Borgoni S., Robinson W., Sinha S., Brandis A., Kerr D. L., Wu W., Sekar A., Giri S., Chung Y., Drago-Garcia D., Danysh B. P., Lauriola M., Fiorentino M., Ardizzoni A., Oren M., Blakely C. M., Ezike J., Wiemann S., Parida L., Bivona T. G., Aqeilan R. I., Brugge J. S., Regev A., Getz G., Ruppin E. & Yarden Y. (2022) Cancer Discovery
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Blockade of the protease ADAM17 ameliorates experimental pancreatitis

Saad M. I., Weng T., Lundy J., Gearing L. J., West A. C., Harpur C. M., Alanazi M., Hodges C., Croagh D., Kumar B., Sagi I., Rose-John S. & Jenkins B. J. (2022) Proceedings of the National Academy of Sciences
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A network of mixed actin polarity in the leading edge of spreading cells

Chung W. L., Eibauer M., Li W., Boujemaa-Paterski R., Geiger B. & Medalia O. (2022) Communications Biology
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Pulse Radiolysis Studies of Temperature Dependent Electron Transfers among Redox Centers in ba3-Cytochrome c Oxidase from Thermus thermophilus: Comparison of A- and B-Type Enzymes

Farver O., Wherland S., Antholine W. E., Gemmen G. J., Chen Y., Pecht I. & Fee J. A. (2022) Biochemistry
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SARS-CoV-2 IgG Antibody Levels in Women with IBD Vaccinated during Pregnancy

Avni Biron I., Maayan Y., Mishael T., Hadar E., Neeman M., Plitman Mayo R., Sela H. Y., Yagel S., Goldenberg R., Ben Ya’acov A., Grisaru Granovsky S., Ollech J. E., Edelman-Klapper H., Rabinowitz K. M., Pauker M. H., Yanai H., Goren S., Cohen D., Dotan I. & Bar-Gil Shitrit A. (2022) Vaccines
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Lung Regeneration by Transplantation of Allogeneic Lung Progenitors Using a Safer Conditioning Regimen and Clinical-grade Reagents

Krentsis I. M., Orgad R., Zheng Y., Lustig E. B., Rosen C., Shezen E., Yadav S., Levi B. N., Assayag M., Berkman N., Quintana H. K., Shoshan E., Blagdon C. & Reisner Y. (2022) Stem Cells Translational Medicine
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Transcriptional regulation of the thymus master regulator Foxn1

Kadouri N., Giladi T., Katz S., Hey J., Ben-Dor S., Damari G., Dassa B., Dobes J., Dieter W., Bähr M., Paulsen M., Haffner-Krausz R., Mall M. A., Plass C., Kafka Y. & Abramson J. (2022) Science Immunology
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Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Muller A., Kohler U. A., Trzebanski S., Vinik Y., Mohan Raju H. R., Girault J., Ben-Chetrit N., Maraver A., Jung S. & Lev S. (2022) Advanced Science
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Germline genetic biomarkers to stratify patients for personalized radiation treatment

Deichaite I., Hopper A., Krockenberger L., Sears T. J., Sutton L., Ray X., Sharabi A., Navon A., Sanghvi P., Carter H. & Moiseenko V. (2022) Journal of Translational Medicine
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Matrix Metalloproteinases Expression Is Associated with SARS-CoV-2-Induced Lung Pathology and Extracellular-Matrix Remodeling in K18-hACE2 Mice

Gutman H., Aftalion M., Melamed S., Politi B., Nevo R., Havusha-Laufer S., Achdout H., Gur D., Israely T., Dachir S., Mamroud E., Sagi I. & Vagima Y. (2022) Viruses
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2021

Peptidomic profiling of cerebrospinal fluid from patients with intracranial saccular aneurysms

Sakaya G. R., Parada C. A., Eichler R. A., Yamaki V. N., Navon A., Heimann A. S., Figueiredo E. G. & Ferro E. S. (2021) Journal of Proteomics
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Prediction of Ovarian Follicular Dominance by MRI Phenotyping of Hormonally Induced Vascular Remodeling

Fellus-Alyagor L., Biton I. E., Dafni H., Bochner F., Rotkopf R., Dekel N. & Neeman M. (2021) Frontiers in Medicine
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TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment

Maddalena M., Mallel G., Nataraj N. B., Shreberk-Shaked M., Hassin O., Mukherjee S., Arandkar S., Rotkopf R., Kapsack A., Lambiase G., Pellegrino B., Ben-Isaac E., Golani O., Addadi Y., Hajaj E., Eilam R., Straussman R., Yarden Y., Lotem M. & Oren M. (2021) Proceedings of the National Academy of Sciences
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Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation

Goldfarb Y., Givony T., Dobeš J., Kadouri N., Zalayat I., Peligero-Cruz C., Damari G., Dassa B., Ben-Dor S., Gruper Y., Oftedal B. E., Bratland E., Erichsen M. M., Berger A., Avin A., Nevo S., Haljasorg U., Kuperman Y., Ulman A., Porat Z., Haffner-Krausz R., Atasoy U., Leshkowitz D., Husebye E. S. & Abramson J. (2021) Journal of Experimental Medicine
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Kynurenic acid- a key metabolite protecting the heart from an ischemic damage

Entin-Meer M., Bigelman E. B., Pasmanik-Chor M. P. C., Dassa B. D., Gross A. G., Itkin M. I., Malitsky S. M., Dorot O. D., Pichinuk E. P., Dezorell N. M. & Keren G. K. (2021) European Heart Journal
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Spatially organized multicellular immune hubs in human colorectal cancer

Pelka K., Hofree M., Chen J. H., Sarkizova S., Pirl J. D., Jorgji V., Bejnood A., Dionne D., Ge W. H., Xu K. H., Chao S. X., Zollinger D. R., Lieb D. J., Reeves J. W., Fuhrman C. A., Hoang M. L., Delorey T., Nguyen L. T., Waldman J., Wakiro I., Klapholz M., Cohen O., Albers J., Smillie C. S., Cuoco M. S., Wu J., Su M., Yeung J., Vijaykumar B., Magnuson A. M., Asinovski N., Moll T., Goder-Reiser M. N., Applebaum A. S., Brais L. K., DelloStritto L. K., Denning S. L., Phillips S. T., Hill E. K., Meehan J. K., Frederick D. T., Sharova T., Kanodia A., Todres E. Z., Jané-Valbuena J., Biton M., Izar B., Lambden C. D., Clancy T. E., Bleday R., Melnitchouk N., Irani J., Kunitake H., Berger D. L., Srivastava A., Hornick J. L., Ogino S., Rotem A., Vigneau S., Johnson B. E., Corcoran R. B., Sharpe A. H., Kuchroo V. K., Ng K., Giannakis M., Nieman L. T., Boland G. M., Aguirre A. J., Anderson A. C., Rozenblatt-Rosen O., Regev A. & Hacohen N. (2021) Cell
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Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans

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Identification and characterization of key long non-coding RNAs in the mouse cochlea

Koffler-Brill T., Taiber S., Anaya A., Bordeynik-Cohen M., Rosen E., Kolla L., Messika-Gold N., Elkon R., Kelley M. W., Ulitsky I. & Avraham K. B. (2021) RNA Biology
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Alternative splicing of the inhibitory immune checkpoint receptor SLAMF6 generates a dominant positive form, boosting T-cell effector functions

Hajaj E., Zisman E., Tzaban S., Merims S., Cohen J., Klein S., Frankenburg S., Sade-Feldman M., Tabach Y., Yizhak K., Navon A., Stepensky P., Hacohen N., Peretz T., Veillette A., Karni R., Eisenberg G. & Lotem M. (2021) Cancer Immunology Research
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Degani N., Lubelsky Y., Perry R. B., Ainbinder E. & Ulitsky I. (2021) PLoS Genetics
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Diffusion is directional: Innovative diffusion tensor imaging to improve prostate cancer detection

Shenhar C., Degani H., Ber Y., Baniel J., Tamir S., Benjaminov O., Rosen P., Furman-Haran E. & Margel D. (2021) Diagnostics
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The prospects of tumor chemosensitivity testing at the single-cell level

Yang C., Yang C., Yarden Y., To K. K. & Fu L. (2021) Drug Resistance Updates
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γδ T cells regulate the intestinal response to nutrient sensing

Sullivan Z. A., Khoury-Hanold W., Lim J., Smillie C., Biton M., Reis B. S., Zwick R. K., Pope S. D., Israni-Winger K., Parsa R., Philip N. H., Rashed S., Palm N., Wang A., Mucida D., Regev A. & Medzhitov R. (2021) Science
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Distinct extracellular–matrix remodeling events precede symptoms of inflammation

Shimshoni E., Adir I., Afik R., Solomonov I., Shenoy A., Adler M., Puricelli L., Sabino F., Savickas S., Mouhadeb O., Gluck N., Fishman S., Werner L., Salame T., Shouval D. S., Varol C., auf dem Keller U., Podestà A., Geiger T., Milani P., Alon U. & Sagi I. (2021) Matrix Biology
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Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models

Marrocco I., Romaniello D., Vaknin I., Drago‐Garcia D., Oren R., Uribe M. L., Belugali Nataraj N., Ghosh S., Eilam R., Salame T., Lindzen M. & Yarden Y. (2021) EMBO Molecular Medicine
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Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits

Giacomelli C., Jung J., Wachter A., Ibing S., Will R., Uhlmann S., Mannsperger H., Sahin Ö., Yarden Y., Beißbarth T., Korf U., Körner C. & Wiemann S. (2021) BMC Cancer
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β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function

Bouti P., Webbers S. D., Fagerholm S. C., Alon R., Moser M., Matlung H. L. & Kuijpers T. W. (2021) Frontiers in Immunology
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Proteomic patterns associated with response to breast cancer neoadjuvant treatment

Shenoy A., Belugali Nataraj N., Perry G., Loayza Puch F., Nagel R., Marin I., Balint N., Bossel N., Pavlovsky A., Barshack I., Kaufman B., Agami R., Yarden Y., Dadiani M. & Geiger T. (2021) Molecular Systems Biology
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Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis

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Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction

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CircRNAs: role in human diseases and potential use as biomarkers

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MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease

Monteiro J. P., Rodor J., Caudrillier A., Scanlon J. P., Spiroski A., Dudnakova T., Pflüger-Müller B., Shmakova A., von Kriegsheim A., Deng L., Taylor R. S., Wilson-Kanamori J. R., Chen S., Stewart K., Thomson A., Mitić T., McClure J. D., Iyinikkel J., Hadoke P. W., Denby L., Bradshaw A. C., Caruso P., Morrell N. W., Kovacic J. C., Ulitsky I., Henderson N. C., Caporali A., Leisegang M. S., Brandes R. P. & Baker A. H. (2021) Circulation Research
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Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis

Bolik J., Krause F., Stevanovic M., Gandraß M., Thomsen I., Schacht S., Rieser E., Müller M., Schumacher N., Fritsch J., Wichert R., Galun E., Bergmann J., Röder C., Schafmayer C., Egberts J., Becker-Pauly C., Saftig P., Lucius R., Schneider-Brachert W., Barikbin R., Adam D., Voss M., Hitzl W., Krüger A., Strilic B., Sagi I., Walczak H., Rose-John S. & Schmidt-Arras D. (2021) Journal of Experimental Medicine
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A Prediction Model to Prioritize Individuals for a SARS-CoV-2 Test Built from National Symptom Surveys

Shoer S., Karady T., Keshet A., Shilo S., Rossman H., Gavrieli A., Meir T., Lavon A., Kolobkov D., Kalka I., Godneva A., Cohen O., Kariv A., Hoch O., Zer-Aviv M., Castel N., Sudre C., Zohar A. E., Irony A., Spector T., Geiger B., Hizi D., Shalev V., Balicer R. & Segal E. (2021) Med
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The key roles of cancer stem cell-derived extracellular vesicles

Su C., Zhang J., Yarden Y. & Fu L. (2021) Signal Transduction and Targeted Therapy
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TNF-α Regulated Endometrial Stroma Secretome Promotes Trophoblast Invasion

You Y., Stelzl P., Joseph D. N., Aldo P. B., Maxwell A. J., Dekel N., Liao A., Whirledge S. & Mor G. (2021) Frontiers in Immunology
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EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

Uribe M. L., Marrocco I. & Yarden Y. (2021) Cancers
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Inefficient splicing curbs noncoding RNA transcription

Gil N. & Ulitsky I. (2021) Nature Structural & Molecular Biology
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Conformation-specific inhibitory anti-mmp-7 monoclonal antibody sensitizes pancreatic ductal adenocarcinoma cells to chemotherapeutic cell kill

Mohan V., Gaffney J. P., Solomonov I., Levin M., Klepfish M., Akbareian S., Grünwald B., Dym O., Eisenstein M., Yu K. H., Kelsen D. P., Krüger A., Edwards D. R. & Sagi I. (2021) Cancers
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Efficient maternal to neonatal transfer of antibodies against SARS-CoV-2 and BNT162b2 mRNA COVID-19 vaccine

Beharier O., Plitman Mayo R., Raz T., Nahum Sacks K., Schreiber L., Suissa-Cohen Y., Chen R., Gomez-Tolub R., Hadar E., Gabbay-Benziv R., Jaffe Moshkovich Y., Biron-Shental T., Shechter-Maor G., Farladansky-Gershnabel S., Yitzhak Sela H., Benyamini-Raischer H., Sela N. D., Goldman-Wohl D., Shulman Z., Many A., Barr H., Yagel S., Neeman M. & Kovo M. (2021) The Journal of Clinical Investigation
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Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentation

Wortzel I., Maik-Rachline G., Yadav S. S., Hanoch T. & Seger R. (2021) iScience
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The GUL-1 Protein Binds Multiple RNAs Involved in Cell Wall Remodeling and Affects the MAK-1 Pathway in Neurospora crassa

Herold I., Zolti A., Garduño-Rosales M., Wang Z., López-Giráldez F., Mouriño-Pérez R. R., Townsend J. P., Ulitsky I. & Yarden O. (2021) Frontiers in Fungal Biology
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Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences

Ross C. J., Rom A., Spinrad A., Gelbard-Solodkin D., Degani N. & Ulitsky I. (2021) Genome Biology
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Roles for growth factors and mutations in metastatic dissemination

Nataraj N. B., Marrocco I. & Yarden Y. (2021) Biochemical Society Transactions
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Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation

Nevo N., Ordonez-moreno L., Gur-cohen S., Avemaria F., Bhattacharya S., Khatib-massalha E., Bertagna M., Haddad M., Chakrabarti P., Ruf W., Lapidot T. & Kollet O. (2021) Leukemia
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Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules

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Avidity optimization of a MAGE-A1-specific TCR with somatic hypermutation

Bassan D., Gozlan Y. M., Sharbi-Yunger A., Tzehoval E., Greenstein E., Bitan L., Friedman N. & Eisenbach L. (2021) European Journal of Immunology
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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

Beyaz S., Chung C., Mou H., Bauer-Rowe K. E., Xifaras M. E., Ergin I., Dohnalova L., Biton M., Shekhar K., Eskiocak O., Papciak K., Ozler K., Almeqdadi M., Yueh B., Fein M., Annamalai D., Valle-Encinas E., Erdemir A., Dogum K., Shah V., Alici-Garipcan A., Meyer H. V., Özata D. M., Elinav E., Kucukural A., Kumar P., McAleer J. P., Fox J. G., Thaiss C. A., Regev A., Roper J., Orkin S. H. & Yilmaz Ö. H. (2021) Cell Stem Cell
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An SNX10-dependent mechanism downregulates fusion between mature osteoclasts

Barnea Zohar M., Winograd-Katz S., Shalev M., Arman E., Reuven N., Roth L., Golani O., Stein M., Thalji F., Kanaan M., Tuckermann J., Geiger B. & Elson A. (2021) Journal of Cell Science
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LFA-1 in T cell priming, differentiation, and effector functions

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Astrocytes in Multiple Sclerosis—Essential Constituents with Diverse Multifaceted Functions

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ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

Brandao R., Kwa M. Q., Yarden Y. & Brakebusch C. (2021) FEBS Open Bio
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Inelastic Electron Tunneling Spectroscopic Analysis of Bias‐Induced Structural Changes in a Solid‐State Protein Junction

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Host succinate is an activation signal for Salmonella virulence during intracellular infection

Rosenberg G., Yehezkel D., Hoffman D., Ciolli Mattioli C., Fremder M., Ben-Arosh H., Vainman L., Nissani N., Hen-Avivi S., Brenner S., Itkin M., Malitsky S., Ohana E., Ben-Moshe N. B. & Avraham R. (2021) Science
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The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

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Furth N., Shilo S., Cohen N., Erez N., Fedyuk V., Schrager A. M., Weinberger A., Dror A. A., Zigron A., Shehadeh M., Sela E., Srouji S., Amit S., Levy I., Segal E., Dahan R., Jones D., Douek D. C. & Shema E. (2021) PLoS ONE
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Elson A., Stein M., Rabie G., Barnea-Zohar M., Winograd-Katz S., Reuven N., Shalev M., Sekeres J., Kanaan M., Tuckermann J. & Geiger B. (2021) Frontiers in Cell and Developmental Biology
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Alternative Splicing of MAPKs in the Regulation of Signaling Specificity

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CCR7 signalosomes are preassembled on tips of lymphocyte microvilli in proximity to LFA-1

Ghosh S., Feigelson S. W., Montresor A., Shimoni E., Roncato F., Legler D. F., Laudanna C., Haran G. & Alon R. (2021) Biophysical Journal
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High-resolution mapping of function and protein binding in an RNA nuclear enrichment sequence

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Host-Dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors

Haga Y., Marrocco I., Noronha A., Uribe M. L., Nataraj N. B., Sekar A., Drago-Garcia D., Borgoni S., Lindzen M., Giri S., Wiemann S., Tsutsumi Y. & Yarden Y. (2021) Cancer Research
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Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation

Canu V., Donzelli S., Sacconi A., Lo Sardo F., Pulito C., Bossel N., Di Benedetto A., Muti P., Botti C., Domany E., Bicciato S., Strano S., Yarden Y. & Blandino G. (2021) Cell Death and Differentiation
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VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells

Jerafi-Vider A., Bassi I., Moshe N., Tevet Y., Hen G., Splittstoesser D., Shin M., Lawson N. D. & Yaniv K. (2021) Cell Reports
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Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

Alon R., Sportiello M., Kozlovski S., Kumar A., Reilly E. C., Zarbock A., Garbi N. & Topham D. J. (2021) Nature Reviews Immunology
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A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella

Hoffman D., Tevet Y., Trzebanski S., Rosenberg G., Vainman L., Solomon A., Hen-Avivi S., Ben-Moshe N. B. & Avraham R. (2021) Immunity
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Temperature Dependence of Charge and Spin Transfer in Azurin

Sang Y., Mishra S., Tassinari F., Karuppannan S. K., Carmieli R., Teo R. D., Migliore A., Beratan D. N., Gray H. B., Pecht I., Fransson J., Waldeck D. H. & Naaman R. (2021) Journal of Physical Chemistry C
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α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.

Jacob R. S., Eichmann C., Dema A., Mercadante D. & Selenko P. (2021) eLife
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Differential cellular responses to adhesive interactions with galectin-8 and fibronectin coated substrates

Li W., Sancho A., Chung W., Vinik Y., Groll J., Zick Y., Medalia O., Bershadsky A. D. & Geiger B. (2021) Journal of Cell Science
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Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma

Singh A., Erijman A., Noronha A., Kumar H., Peleg Y., Yarden Y. & Shifman J. M. (2021) Journal of Biological Chemistry
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What Can We Learn from Protein-Based Electron Transport Junctions?

Cahen D., Pecht I. & Sheves M. (2021) Journal of Physical Chemistry Letters
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SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis

Finkel Y., Gluck A., Nachshon A., Winkler R., Fisher T., Rozman B., Mizrahi O., Lubelsky Y., Zuckerman B., Slobodin B., Yahalom-Ronen Y., Tamir H., Ulitsky I., Israely T., Paran N., Schwartz M. & Stern-Ginossar N. (2021) Nature
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Live imaging of chromatin distribution reveals novel principles of nuclear architecture and chromatin compartmentalization

Amiad-Pavlov D., Lorber D., Bajpai G., Reuveny A., Roncato F., Alon R., Safran S. & Volk T. (2021) Science Advances
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Nonuniformity in Periodontal Ligament: Mechanics and Matrix Composition

Connizzo B. K., Sun L., Lacin N., Gendelman A., Solomonov I., Sagi I., Grodzinsky A. J. & Naveh G. R. (2021) Journal of Dental Research
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Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells

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Beyond cells: The extracellular circulating 20S proteasomes

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P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas

Rousso-Noori L., Mastandrea I., Talmor S., Waks T., Globerson Levin A., Haugas M., Teesalu T., Alvarez-Vallina L., Eshhar Z. & Friedmann-Morvinski D. (2021) Nature Communications
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SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells

Zagorac S., de Giorgio A., Dabrowska A., Kalisz M., Casas-Vila N., Cathcart P., Yiu A., Ottaviani S., Degani N., Lombardo Y., Tweedie A., Nissan T., Vance K. W., Ulitsky I., Stebbing J. & Castellano L. (2021) Cancer Research
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Deuterium Magnetic Resonance Imaging and the Discrimination of Fetoplacental Metabolism in Normal and L-NAME-Induced Preeclamptic Mice

Markovic S., Roussel T., Neeman M. & Frydman L. (2021) Metabolites
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Hemopressin as a breakthrough for the cannabinoid field

Heimann A. S., Dale C. S., Guimarães F. S., Reis R. A., Navon A., Shmuelov M. A., Rioli V., Gomes I., Devi L. L. & Ferro E. S. (2021) Neuropharmacology
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β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection

Guenther C., Faisal I., Fusciello M., Sokolova M., Harjunpää H., Ilander M., Tallberg R., Vartiainen M. K., Alon R., Gonzalez-Granado J., Cerullo V. & Fagerholm S. C. (2021) Cancer Immunology Research
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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

Ghosh S., Nataraj N. B., Noronha A., Patkar S., Sekar A., Mukherjee S., Winograd-Katz S., Kramarski L., Verma A., Lindzen M., Garcia D. D., Green J., Eisenberg G., Gil-Henn H., Basu A., Lender Y., Weiss S., Oren M., Lotem M., Geiger B., Ruppin E. & Yarden Y. (2021) Cell Reports
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Generation of specialized blood vessels through transdifferentiation of lymphatic endothelial cells

Das R. N., Bassi I., Han Y., Lambiase G., Tevet Y., Moshe N., Safriel S. R., Nicenboim J., Brückner M., Hirsch D., Eilam-Altstadter R., Herzog W., Poss K. D. & Yaniv K. (2021) BioRxiv
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Intratumoral heterogeneity in cancer progression and response to immunotherapy

Vitale I., Shema E., Loi S. & Galluzzi L. (2021) Nature Medicine
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Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53

Lindzen M., Ghosh S., Noronha A., Drago D., Nataraj N. B., Leitner O., Carvalho S., Zmora E., Sapoznik S., Shany K. B., Levanon K., Aderka D., Ramírez B. S., Dahlhoff M., McNeish I. & Yarden Y. (2021) Oncogene
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A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages

Kim J., Kolesnikov M., Peled-Hajaj S., Scheyltjens I., Xia Y., Trzebanski S., Haimon Z., Shemer A., Lubart A., Van Hove H., Chappell-Maor L., Boura-Halfon S., Movahedi K., Blinder P. & Jung S. (2021) Immunity
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Novel transcript discovery expands the repertoire of pathologically-associated, long non-coding rnas in vascular smooth muscle cells

Bennett M., Ulitsky I., Alloza I., Vandenbroeck K., Miscianinov V., Mahmoud A. D., Ballantyne M., Rodor J. & Baker A. H. (2021) International Journal of Molecular Sciences
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Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis

Aharoni R., Eilam R., Lerner S., Shavit-Stein E., Dori A., Chapman J. & Arnon R. (2021) International Journal of Molecular Sciences
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Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution

Kim K. L., van Galen P., Hovestadt V., Rahme G. J., Andreishcheva E. N., Shinde A., Gaskell E., Jones D. R., Shema E. & Bernstein B. E. (2021) Cell Reports Methods
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The doctor prescribed fat free diet for stem cell mobilization

Kollet O., Khatib-Massalha E. & Lapidot T. (2021) Haematologica
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Food colors caught red-handed

Kulkarni A. & Jung S. (2021) Cell Metabolism
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2020

Titration of myelin oligodendrocyte glycoprotein (MOG) - Induced experimental autoimmune encephalomyelitis (EAE) model

Aharoni R., Globerman R., Eilam R., Brenner O. & Arnon R. (2020) Journal of Neuroscience Methods
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Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours

Bochner F., Fellus-Alyagor L., Ketter D., Golani O., Biton I. & Neeman M. (2020) British Journal of Cancer
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Talin-activated vinculin interacts with branched actin networks to initiate bundles

Boujemaa-Paterski R., Martins B., Eibauer M., Beales C. T., Geiger B. & Medalia O. (2020) eLife
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Integrated metabolomics and proteomics of symptomatic and early pre-symptomatic states of colitis

Shimshoni E., Ghini V., Solomonov I., Luchinat C., Sagi I. & Turano P. (2020) BioRxiv
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Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Konishi H., Okamoto T., Hara Y., Komine O., Tamada H., Maeda M., Osako F., Kobayashi M., Nishiyama A., Kataoka Y., Takai T., Udagawa N., Jung S., Ozato K., Tamura T., Tsuda M., Yamanaka K., Ogi T., Sato K. & Kiyama H. (2020) The EMBO Journal
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Plasticity of Monocyte Development and Monocyte Fates

Trzebanski S. & Jung S. (2020) Immunology Letters
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Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma

Weidner P., Soehn M., Schroeder T., Helm L., Hauber V., Gutting T., Betge J., Roecken C., Rohrbacher F. N., Pattabiraman V. R., Bode J. W., Seger R., Saar D., Nunes-Alves A., Wade R. C., Ebert M. P. A. & Burgermeister E. (2020) Oncogenesis
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ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

Aharonov A., Shakked A., Umansky K. B., Savidor A., Genzelinakh A., Kain D., Lendengolts D., Revach O. Y., Morikawa Y., Dong J., Levin Y., Geiger B., Martin J. F. & Tzahor E. (2020) Nature Cell Biology
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Peptide Interference with APP and Tau Association: Relevance to Alzheimer's Disease Amelioration

Maron R., Armony G., Tsoory M., Wilchek M., Frenkel D. & Arnon R. (2020) International Journal of Molecular Sciences
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Nucleic acid fragmentation on the millisecond timescale using a conventional X-ray rotating anode source: Application to protein-DNA footprinting

Henn A., Halfon J., Kela I., Orion I. & Sagi I. (2020) Nucleic Acids Research
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Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor-Thr(701) phosphorylation

Gaviraghi M., Rabellino A., Andolfo A., Brand M., Brombin C., Bagnato P., De Feudis G., Raimondi A., Locatelli A., Tosoni D., Mazza D., Gianni L., Tonon G., Yarden Y., Tacchetti C. & Daniele T. (2020) Scientific Reports
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A research and training center model – The Weizmann Institute of Science

Pecht I. (2020) Turkish Journal of Biochemistry
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Functional annotation of human long noncoding RNAs via molecular phenotyping

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Protein Binding and Orientation Matter: Bias-Induced Conductance Switching in a Mutated Azurin Junction

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The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis

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Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers

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Mitochondrial carrier homolog 2 is necessary for AML survival

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Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts

Kim K., Hu W., Audenet F., Almassi N., Hanrahan A. J., Murray K., Bagrodia A., Wong N., Clinton T. N., Dason S., Mohan V., Jebiwott S., Nagar K., Gao J., Penson A., Hughes C., Gordon B., Chen Z., Dong Y., Watson P. A., Alvim R., Elzein A., Gao S. P., Cocco E., Santin A. D., Ostrovnaya I., Hsieh J. J., Sagi I., Pietzak E. J., Hakimi A. A., Rosenberg J. E., Iyer G., Vargas H. A., Scaltriti M., Al-Ahmadie H., Solit D. B. & Coleman J. A. (2020) Nature Communications
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Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

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An NMR-Based Biosensor to Measure Stereospecific Methionine Sulfoxide Reductase Activities in Vitro and in Vivo

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Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer

Borgoni S., Sofyalı E., Soleimani M., Wilhelm H., Müller-Decker K., Will R., Noronha A., Beumers L., Verschure P. J., Yarden Y., Magnani L., van Kampen A. H., Moerland P. D. & Wiemann S. (2020) Cancers
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Formation and Growth of Cardiac Lymphatics during Embryonic Development, Heart Regeneration, and Disease

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Effect of IV Administration of a Gadolinium-Based Contrast Agent on Breast Diffusion-Tensor Imaging

Scaranelo A. M., Degani H., Grobgeld D., Talbot N., Bodolai K. & Furman-Haran E. (2020) American Journal of Roentgenology
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Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells

Delacher M., Barra M. M., Herzig Y., Eichelbaum K., Rafiee M., Richards D. M., Traeger U., Hofer A., Kazakov A., Braband K. L., Gonzalez M., Woehrl L., Schambeck K., Imbusch C. D., Abramson J., Krijgsveld J. & Feuerer M. (2020) iScience
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A framework for identifying regional outbreak and spread of COVID-19 from one-minute population-wide surveys

Rossman H., Keshet A., Shilo S., Gavrieli A., Bauman T., Cohen O., Shelly E., Balicer R., Geiger B., Dor Y. & Segal E. (2020) Nature Medicine
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Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody

Cohen L., Sagi I., Bigelman E., Solomonov I., Aloshin A., Ben-Shoshan J., Rozenbaum Z., Keren G. & Entin-Meer M. (2020) PLoS ONE
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The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction

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Solid-State Electron Transport via the Protein Azurin is Temperature-Independent Down to 4 K

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Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

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The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy

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Shemer A., Scheyltjens I., Frumer G. R., Kim J., Grozovski J., Ayanaw S., Dassa B., Van Hove H., Chappell-Maor L., Boura-Halfon S., Leshkowitz D., Mueller W., Maggio N., Movahedi K. & Jung S. (2020) Immunity
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Coherent Electron Transport across a 3 nm Bioelectronic Junction Made of Multi-Heme Proteins

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IL18 signaling promotes homing of mature Tregs into the thymus

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Differential tissue stiffness of body column facilitates locomotion of Hydra on solid substrates

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Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells

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Glatiramer acetate increases T- and B -regulatory cells and decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) in an animal model of multiple sclerosis

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Polyglutamine-Related Aggregates Can Serve as a Potent Antigen Source for Cross-Presentation by Dendritic Cells

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Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma

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Regulation of hematopoietic stem cell function by nitric oxide signaling

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Novel multimodal molecular imaging of Vitamin H (Biotin) transporter activity in the murine placenta

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Novel Hexb-based tools for studying microglia in the CNS

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Solid-State Protein Junctions: Cross-Laboratory Study Shows Preservation of Mechanism at Varying Electronic Coupling

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Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis: Implications for Cancer Lymphangiogenesis

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Bone marrow dendritic cells support the survival of chronic lymphocytic leukemia cells in a CD84 dependent manner

Barak A. F., Lewinsky H., Perpinial M., Huber V., Radomir L., Kramer M. P., Sever L., Wolf Y., Shapiro M., Herishanu Y., Jung S., Becker-Herman S. & Shachar I. (2020) Oncogene
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Google maps for tissues: Multiscale imaging of biological systems and disease

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Megadalton-sized Dityrosine Aggregates of α-Synuclein Retain High Degrees of Structural Disorder and Internal Dynamics

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Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

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LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis

Klepfish M., Gross T., Vugman M., Afratis N. A., Havusha-Laufer S., Brazowski E., Solomonov I., Varol C. & Sagi I. (2020) Frontiers in Immunology
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ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation

Ghosh S., Di Bartolo V., Tubul L., Shimoni E., Kartvelishvily E., Dadosh T., Feigelson S. W., Alon R., Alcover A. & Haran G. (2020) Cell Reports
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A guide to naming human non-coding RNA genes

Seal R. L., Chen L., Griffiths-Jones S., Lowe T. M., Mathews M. B., O'Reilly D., Pierce A. J., Stadler P. F., Ulitsky I., Wolin S. L. & Bruford E. A. (2020) EMBO Journal
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

Hoshino A., Kim H. S., Bojmar L., Gyan K. E., Cioffi M., Hernandez J., Zambirinis C. P., Rodrigues G., Molina H., Heissel S., Mark M. T., Steiner L., Benito-Martin A., Lucotti S., Di Giannatale A., Offer K., Nakajima M., Williams C., Nogués L., Pelissier Vatter F. A., Hashimoto A., Davies A. E., Freitas D., Kenific C. M., Ararso Y., Buehring W., Lauritzen P., Ogitani Y., Sugiura K., Takahashi N., Alečković M., Bailey K. A., Jolissant J. S., Wang H., Harris A., Schaeffer L. M., García-Santos G., Posner Z., Balachandran V. P., Khakoo Y., Raju G. P., Scherz A., Sagi I., Scherz-Shouval R., Yarden Y., Oren M., Malladi M., Petriccione M., De Braganca K. C., Donzelli M., Fischer C., Vitolano S., Wright G. P., Ganshaw L., Marrano M., Ahmed A., DeStefano J., Danzer E., Roehrl M. H. A., Lacayo N. J., Vincent T. C., Weiser M. R., Brady M. S., Meyers P. A., Wexler L. H., Ambati S. R., Chou A. J., Slotkin E. K., Modak S., Roberts S. S., Basu E. M., Diolaiti D., Krantz B. A., Cardoso F., Simpson A. L., Berger M., Rudin C. M., Simeone D. M., Jain M., Ghajar C. M., Batra S. K., Stanger B. Z., Bui J., Brown K. A., Rajasekhar V. K., Healey J. H., de Sousa M., Kramer K., Sheth S., Baisch J., Pascual V., Heaton T. E., La Quaglia M. P., Pisapia D. J., Schwartz R., Zhang H., Liu Y., Shukla A., Blavier L., DeClerck Y. A., LaBarge M., Bissell M. J., Caffrey T. C., Grandgenett P. M., Hollingsworth M. A., Bromberg J., Costa-Silva B., Peinado H., Kang Y., Garcia B. A., O'Reilly E. M., Kelsen D., Trippett T. M., Jones D. R., Matei I. R., Jarnagin W. R. & Lyden D. (2020) Cell
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Immune Computation and COVID-19 Mortality: A Rationale for IVIg

Cohen I. R., Efroni S. & Atlan H. (2020) Critical Reviews in Immunology
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DNA Vaccination With Hsp70 Protects Against Systemic Lupus Erythematosus in (NZB x NZW)F1 Mice

Liu A., Ferretti C., Shi F., Cohen I. R., Quintana F. J. & La Cava A. (2020) Arthritis & Rheumatology
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Nuclear P38: Roles in Physiological and Pathological Processes and Regulation of Nuclear Translocation

Maik-Rachline G., Lifshits L. & Seger R. (2020) International Journal of Molecular Sciences
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Less is more: reducing the number of administered chimeric antigen receptor T cells in a mouse model using a mathematically guided approach

Globerson Levin A., Kronik N., Shiloach T., Waks T., Eshhar Z. & Vainstein V. (2020) Cancer Immunology Immunotherapy
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Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

Keshet R., Lee J. S., Adler L., Iraqi M., Ariav Y., Lim L. Q. J., Lerner S., Rabinovich S., Oren R., Katzir R., Tishler H. W., Stettner N., Goldman O., Landesman H., Galai S., Kuperman Y., Kuznetsov Y., Brandis A., Mehlman T., Malitsky S., Itkin M., Koehler S. E., Zhao Y., Talsania K., Shen T., Peled N., Ulitsky I., Porgador A., Ruppin E. & Erez A. (2020) Nature Cancer
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Perpheral blood cell mitochondrial dysfunction in myelodysplastic syndrome can be improved by a combination of coenzyme Q10 and carnitine: Blood cell mitochondrial dysfunction in myelodysplastic syndrome

Filanovsky K., Haran M., Mirkin V., Braester A., Shevetz O., Stanevsky A., Sigler E., Votinov E., Zalzman-Amir Y., Berrebi A., Gross A. & Shvidel L. (2020) Mediterranean Journal of Hematology and Infectious Diseases
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Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases (ERKs)

Chuderland D., Marmor G., Shainskaya A. & Seger R. (2020) Cellular Physiology and Biochemistry
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TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge

Gross-Vered M., Shmuel-Galia L., Zarmi B., Humphries F., Thaiss C., Salame T., David E., Chappell-Maor L., Fitzgerald K. A., Shai Y. & Jung S. (2020) Journal of Immunology
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Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice

Stein M., Barnea-Zohar M., Shalev M., Arman E., Brenner O., Winograd-Katz S., Gerstung J., Thalji F., Kanaan M., Elinav H., Stepensky P., Geiger B., Tuckermann J. & Elson A. (2020) Bone
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BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression

Cohen B., Tempelhof H., Raz T., Oren R., Nicenboim J., Bochner F., Even R., Jelinski A., Eilam R., Ben-Dor S., Adaddi Y., Golani O., Lazar S., Yaniv K. & Neeman M. (2020) Life Science Alliance
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Biomechanical regulation of focal adhesion and invadopodia formation

Revach O. Y., Grosheva I. & Geiger B. (2020) Journal of Cell Science
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Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells

Elisha Y., Sagi Y., Klein G., Straussman R. & Geiger B. (2019) Philosophical Transactions of the Royal Society B: Biological Sciences
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Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (Scientific Reports, (2017), 7, 1, (16345), 10.1038/s41598-017-16558-0)

Arafeh R., Flores K., Keren-Paz A., Maik-Rachline G., Gutkind N., Rosenberg S., Seger R. & Samuels Y. (2019) Scientific Reports
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A universal anti-cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survival

Sharbi-Yunger A., Grees M., Cafri G., Bassan D., Eichmuller S. B., Tzehoval E., Utikal J., Umansky V. & Eisenbach L. (2019) International Journal of Cancer
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Comparative analysis of CreER transgenic mice for the study of brain macrophages: A case study

Chappell-Maor L., Kolesnikov M., Kim J., Shemer A., Haimon Z., Grozovski J., Boura-Halfon S., Masuda T., Prinz M. & Jung S. (2019) European Journal of Immunology
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Predictive models of subcellular localization of long RNAs

Zuckerman B. & Ulitsky I. (2019) RNA
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Inhibition of a pancreatic cancer model by cooperative pairs of clinically approved and experimental antibodies

Maron R., Schechter B., Nataraj N. B., Ghosh S., Romaniello D., Marrocco I., Noronha A., Carvalho S., Yarden Y. & Sela M. (2019) Biochemical and Biophysical Research Communications
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Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

Zviran A., Mor N., Rais Y., Gingold H., Peles S., Chomsky E., Viukov S., Buenrostro J. D., Scognamiglio R., Weinberger L., Manor Y. S., Krupalnik V., Zerbib M., Hezroni H., Jaitin D. A., Larastiaso D., Gilad S., Benjamin S., Gafni O., Mousa A., Ayyash M., Sheban D., Bayerl J., Aguilera-Castrejon A., Massarwa R., Maza I., Hanna S., Stelzer Y., Ulitsky I., Greenleaf W. J., Tanay A., Trumpp A., Amit I., Pilpel Y., Novershtern N. & Hanna J. H. (2019) Cell Stem Cell
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Novel Approaches for Extracellular Matrix Targeting in Disease Treatment

Afratis N. A. & Sagi I. (2019) , The Extracellular Matrix
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Quo Vadis Biomolecular NMR Spectroscopy?

Selenko P. (2019) International Journal of Molecular Sciences
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AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer

Kubli S. P., Bassi C., Roux C., Wakeham A., Gobl C., Zhou W., Jafari S. M., Snow B., Jones L., Palomero L., Thu K. L., Cassetta L., Soong D., Berger T., Ramachandran P., Baniasadi S. P., Duncan G., Lindzen M., Yarden Y., Herranz C., Lazaro C., Chu M. F., Haight J., Tinto P., Silvester J., Cescon D. W., Petit A., Pettersson S., Pollard J. W., Mak T. W., Pujana M. A., Cappello P. & Gorrini C. (2019) Proceedings of the National Academy of Sciences
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Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

Gancz D., Raftrey B. C., Perlmoter G., Marin-Juez R., Semo J., Matsuoka R. L., Karra R., Raviv H., Moshe N., Addadi Y., Golani O., Poss K. D., Red-Horse K., Stainier D. Y. R. & Yaniv K. (2019) eLife
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PAR1 Expression Predicts Clinical G-CSF CD34+ HSPC Mobilization and Repopulation Potential in Transplanted Patients

Nevo N., Zuckerman T., Gur-Cohen S., Kollet O., Avemaria F., Shpall E. J., Mendt M. C., Nagler A., Brenner B., Ben-Arush M. & Lapidot T. (2019) HemaSphere
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The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids

Seneviratne A. K., Xu M., Henao J. J. A., Fajardo V. A., Hao Z., Voisin V., Xu G. W., Hurren R., Kim S., MacLean N., Wang X., Gronda M., Jeyaraju D., Jitkova Y., Ketela T., Mullokandov M., Sharon D., Thomas G., Chouinard-Watkins R., Hawley J. R., Schafer C., Yau H. L., Khuchua Z., Arnan A., Al-awar R., Gross A., Claypoo S. M., Bazinet R., Lupien M., Chan S., De Carvalho D. D., Minden M. D., Bader G. D., Stark K. D., LeBlanc P. & Schimmer A. D. (2019) Cell Stem Cell
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Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration

Yadav S. K., Stojkov D., Feigelson S. W., Roncato F., Simon H., Yousefi S. & Alon R. (2019) Journal of Leukocyte Biology
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The Nuclear Translocation of Mitogen-Activated Protein Kinases: Molecular Mechanisms and Use as Novel Therapeutic Target

Flores K., Yadav S. S., Katz A. A. & Seger R. (2019) Neuroendocrinology
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Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage

Wichert R., Scharfenberg F., Colmorgen C., Koudelka T., Schwarz J., Wetzel S., Potempa B., Potempa J., Bartsch J. W., Sagi I., Tholey A., Saftig P., Rose-John S. & Becker-Pauly C. (2019) FASEB Journal
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Persistent Chemiluminescent Glow of Phenoxy-dioxetane Luminophore Enables Unique CRET-Based Detection of Proteases

Hananya N., Press O., Das A., Scomparin A., Satchi-Fainaro R., Sagi I. & Shabat D. (2019) Chemistry-A European Journal
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Sample Preparation of Extracellular Matrix of Murine Colons for Scanning Electron Microscopy

Shimshoni E. & Sagi I. (2019) , Collagen
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Transient p53-Mediated Regenerative Senescence in the Injured Heart

Sarig R., Rimmer R., Bassat E., Zhang L., Umansky K. B., Lendengolts D., Perlmoter G., Yaniv K. & Tzahor E. (2019) Circulation
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Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution

Shema E., Bernstein B. E. & Buenrostro J. D. (2019) Nature Genetics
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Noncoding RNA: Aging well with Norad

Marques F. C. & Ulitsky I. (2019) eLife
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Early disruption of the alveolar-capillary barrier in a ricin-induced ARDS mouse model: neutrophil-dependent and -independent impairment of junction proteins

Sapoznikov A., Gal Y., Falach R., Sagi I., Ehrlich S., Lerer E., Makovitzki A., Aloshin A., Kronman C. & Sabo T. (2019) American Journal Of Physiology-Lung Cellular And Molecular Physiology
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Molecular pathways of senescence regulate placental structure and function

Gal H., Lysenko M., Stroganov S., Vadai E., Youssef S. A., Tzadikevitch-Geffen K., Rotkopf R., Biron-Shental T., de Bruin A., Neeman M. & Krizhanovsky V. (2019) EMBO Journal
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Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

Cheng C., Biton M., Haber A. L., Gunduz N., Eng G., Gaynor L. T., Tripathi S., Calibasi-Koca G., Rickelt S., Butty V. L., Moreno-Serrano M., Iqbal A. M., Bauer-Rowe K. E., Imada S., Ulutas M. S., Mylonas C., Whary M. T., Levine S. S., Basbinar Y., Hynes R. O., Mino-Kenudson M., Deshpande V., Boyer L. A., Fox J. G., Terranova C., Rai K., Piwnica-Worms H., Mihaylova M. M., Regev A. & Yilmaz O. H. (2019) Cell
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The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

Mahmoud A. D., Ballantyne M. D., Miscianinov V., Pinel K., Hung J., Scanlon J. P., Iyinikkel J., Kaczynski J., Tavares A. S., Bradshaw A. C., Mills N. L., Newby D. E., Caporali A., Gould G. W., George S. J., Ulitsky I., Sluimer J. C., Rodor J. & Baker A. H. (2019) Circulation Research
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In-cell identification and measurement of RNA-protein interactions

Graindorge A., Pinheiro I., Nawrocka A., Mallory A. C., Tsvetkov P., Gil N., Carolis C., Buchholz F., Ulitsky I., Heard E., Taipale M. & Shkumatava A. (2019) Nature Communications
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Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

Smillie C. S., Biton M., Ordovas-Montanes J., Sullivan K. M., Burgin G., Graham D. B., Herbst R. H., Rogel N., Slyper M., Waldman J., Sud M., Andrews E., Velonias G., Haber A. L., Jagadeesh K., Vickovic S., Yao J., Stevens C., Dionne D., Nguyen L. T., Villani A., Hofree M., Creasey E. A., Huang H., Rozenblatt-Rosen O., Garber J. J., Khalili H., Desch A. N., Daly M. J., Ananthakrishnan A. N., Shalek A. K., Xavier R. J. & Regev A. (2019) Cell
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Magnetic Resonance Imaging Reveals Distinct Roles for Tissue Transglutaminase and Factor XIII in Maternal Angiogenesis during Early Mouse Pregnancy

Cohen G., Hadas R., Stefania R., Pagoto A., Ben-Dor S., Kohen F., Longo D., Elbaz M., Dekel N., Gershon E., Aime S. & Neeman M. (2019) Arteriosclerosis, Thrombosis, and Vascular Biology
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Obesity and dysregulated central and peripheral macrophage-neuron cross-talk

Boura-Halfon S., Pecht T., Jung S. & Rudich A. (2019) European Journal of Immunology
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Long noncoding RNAs in development and regeneration of the neural lineage

Hezroni H., Perry R. B. T. & Ulitsky I. (2019) Cold Spring Harbor Symposia on Quantitative Biology
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Next-generation CD8 memory veto T cells directed against memory antigens

Or-Geva N., Gidron-Budovsky R., Sidlik-Muskatel R., Singh A. K. & Reisner Y. (2019) Leukemia
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Rbpj expression in regulatory T cells is critical for restraining T(H)2 responses

Delacher M., Schmidl C., Herzig Y., Breloer M., Hartmann W., Brunk F., Kaegebein D., Traeger U., Hofer A., Bittner S., Weichenhan D., Imbusch C. D., Hotz-Wagenblatt A., Hielscher T., Breiling A., Federico G., Groene H., Schmid R. M., Rehli M., Abramson J. & Feuerer M. (2019) Nature Communications
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The ADAM17 Protease Promotes Tobacco Smoke Carcinogen-induced Lung Tumourigenesis

Saad M. I., McLeod L., Yu L., Ebi H., Ruwanpura S., Sagi I., Rose-John S. & Jenkins B. J. (2019) Carcinogenesis
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Glatiramer Acetate: from Bench to Bed and Back

Arnon R. & Aharoni R. (2019) Israel Medical Association Journal
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Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells

Revach O., Sandler O., Samuels Y. & Geiger B. (2019) Cancer Research
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Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis

Betin V., Penaranda C., Bandyopadhyay N., Yang R., Abitua A., Bhattacharyya R. P., Fan A., Avraham R., Livny J., Shoresh N. & Hung D. T. (2019) Scientific Reports
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Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology

Alex A., Piano V., Polley S., Stuiver M., Voss S., Ciossani G., Overlack K., Voss B., Wohlgemuth S., Petrovic A., Wu Y., Selenko P., Musacchio A. & Maffini S. (2019) eLife
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Daily light and darkness onset and circadian rhythms metabolically synchronize hematopoietic stem cell differentiation and maintenance: The role of bone marrow norepinephrine, tumor necrosis factor, and melatonin cycles

Golan K., Kollet O., Markus R. P. & Lapidot T. (2019) Experimental Hematology
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The circRNA-microRNA code: emerging implications for cancer diagnosis and treatment

Verduci L., Strano S., Yarden Y. & Blandino G. (2019) Molecular Oncology
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Optimizing T-cell receptor avidity with somatic hypermutation

Bassan D., Gozlan Y. M., Sharbi-Yunger A., Tzehoval E. & Eisenbach L. (2019) International Journal of Cancer
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Cancer immunotherapy: The dawn of antibody cocktails

Marrocco I., Romaniello D. & Yarden Y. (2019) , Human Monoclonal Antibodies , Methods and Protocols
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Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

Ben-Moshe N. B., Hen-Avivi S., Levitin N., Yehezkel D., Oosting M., Joosten L. A. B., Netea M. G. & Avraham R. (2019) Nature Communications
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Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators

Conniot J., Scomparin A., Peres C., Yeini E., Pozzi S., Matos A., Kleiner R., Moura L. I. F., Zupancic E., Viana A. S., Doron H., Gois P. M. P., Erez N., Jung S., Satchi-Fainaro R. & Florindo H. F. (2019) Nature Nanotechnology
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DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node

Curato C., Bernshtein B., Zupancic E., Dufner A., Jaitin D., Giladi A., David E., Chappell-Maor L., Leshkowitz D., Knobeloch K., Amit I., Florindo H. F. & Jung S. (2019) Frontiers in Immunology
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Tuft cells: From the mucosa to the thymus

Nevo S., Kadouri N. & Abramson J. (2019) Immunology Letters
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ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad M. I., Alhayyani S., McLeod L., Yu L., Alanazi M., Deswaerte V., Tang K., Jarde T., Smith J. A., Prodanovic Z., Tate M. D., Balic J. J., Watkins D. N., Cain J. E., Bozinovski S., Algar E., Kohmoto T., Ebi H., Ferlin W., Garbers C., Ruwanpura S., Sagi I., Rose-John S. & Jenkins B. J. (2019) EMBO Molecular Medicine
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Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

Geirsdottir L., David E., Keren-Shaul H., Weiner A., Bohlen S. C., Neuber J., Balic A., Giladi A., Sheban F., Dutertre C., Pfeifle C., Peri F., Raffo-Romero A., Vizioli J., Matiasek K., Scheiwe C., Meckel S., Maetz-Rensing K., van der Meer F., Thormodsson F. R., Stadelmann C., Zilkha N., Kimchi T., Ginhoux F., Ulitsky I., Erny D., Amit I. & Prinz M. (2019) Cell
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Intercellular pathways from the vasculature to the forming bone in the zebrafish larval caudal fin: Possible role in bone formation

Akiva A., Nelkenbaum O., Schertel A., Yaniv K., Weiner S. & Addadi L. (2019) Journal of Structural Biology
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Microglial SIRP alpha regulates the emergence of CD11c(+) microglia and demyelination damage in white matter

Sato-Hashimoto M., Nozu T., Toriba R., Horikoshi A., Akaike M., Kawamoto K., Hirose A., Hayashi Y., Nagai H., Shimizu W., Saiki A., Ishikawa T., Elhanbly R., Kotani T., Murata Y., Saito Y., Naruse M., Shibasaki K., Oldenborg P., Jung S., Matozaki T., Fukazawa Y. & Ohnishi H. (2019) eLife
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The Immune System Computes the State of the Body: Crowd Wisdom, Machine Learning, and Immune Cell Reference Repertoires Help Manage Inflammation

Cohen I. R. & Efroni S. (2019) Frontiers in Immunology
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Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability

Rom A., Melamed L., Gil N., Goldrich M. J., Kadir R., Golan M., Biton I., Perry R. B. & Ulitsky I. (2019) Nature Communications
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Alternative 3 UTRs direct localization of functionally diverse protein isoforms in neuronal compartments

Mattioli C. C., Rom A., Franke V., Imami K., Arrey G., Terne M., Woehler A., Akalin A., Ulitsky I. & Chekulaeva M. (2019) Nucleic Acids Research
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Microglia Biology: One Century of Evolving Concepts

Prinz M., Jung S. & Priller J. (2019) Cell
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Nuclear ERK: Mechanism of Translocation, Substrates, and Role in Cancer

Maik-Rachline G., Hacohen A. & Seger R. (2019) International Journal of Molecular Sciences
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IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response

Bernshtein B., Curato C., Ioannou M., Thaiss C. A., Gross-Vered M., Kolesnikov M., Wang Q., David E., Chappell-Maor L., Harmelin A., Elinav E., Thakker P., Papayannopoulos V. & Jung S. (2019) Science immunology
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Collagen: Methods and protocols

Sagi I. & Afratis N. (2019)
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Bacillus Calmette-Guerin (BCG) therapy lowers the incidence of Alzheimer's disease in bladder cancer patients

Gofrit O. N., Klein B. Y., Cohen I. R., Ben-Hur T., Greenblatt C. L. & Bercovier H. (2019) PLoS ONE
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UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

Wolf Y., Bartok O., Patkar S., Eli G. B., Cohen S., Litchfield K., Levy R., Jiménez-Sánchez A., Trabish S., Lee J. S., Karathia H., Barnea E., Day C., Cinnamon E., Stein I., Solomon A., Bitton L., Pérez-Guijarro E., Dubovik T., Shen-Orr S. S., Miller M. L., Merlino G., Levin Y., Pikarsky E., Eisenbach L., Admon A., Swanton C., Ruppin E. & Samuels Y. (2019) Cell
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A conversation with Igor Ulitsky

Ulitsky I. (2019) Cold Spring Harbor Symposia on Quantitative Biology
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Cognitive impairment in an animal model of multiple sclerosis and its amelioration by glatiramer acetate

Aharoni R., Schottlender N., Bar-Lev D. D., Eilam R., Sela M., Tsoory M. & Arnon R. (2019) Scientific Reports
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Avraham Ben-Nun-Pioneer, fighter, friend: Obituary

Cohen I. R. & Wekerle H. (2019) European Journal of Immunology
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DNA-catching BM macrophages set hematopoiesis

Jung S. (2019) Blood
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Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression

Das A., Mohan V., Krishnaswamy V. R., Solomonov I. & Sagi I. (2019) Cancer and Metastasis Reviews
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A Solid-State Protein Junction Serves as a Bias-Induced Current Switch

Fereiro J. A., Kayser B., Romero-Muniz C., Vilan A., Dolgikh D. A., Chertkova R., Cuevas J. C., Zotti L. A., Pecht I., Sheves M. & Cahen D. (2019) Angewandte Chemie - International Edition
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MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy

Owyong M., Chou J., van den Bijgaart R. J., Kong N., Efe G., Maynard C., Talmi-Frank D., Solomonov I., Koopman C., Hadler-Olsen E., Headley M., Lin C., Wang C., Sagi I., Werb Z. & Plaks V. (2019) Life Science Alliance
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Cells, drugs and NMR

Siegal G. & Selenko P. (2019) Journal of Magnetic Resonance
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Endothelial function and dysfunction in the cardiovascular system: the long non-coding road

Monteiro J. P., Bennett M., Rodor J., Caudrillier A., Ulitsky I. & Baker A. H. (2019) Cardiovascular Research
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Toward safer haploidnetical hematopoietic stem cell transplantation

Sidlik-Muskatel R. & Reisner Y. (2019) Bone Marrow Transplantation
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ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma

Srivastava S., Nataraj N. B., Sekar A., Ghosh S., Bornstein C., Drago-Garcia D., Roth L., Romaniello D., Marrocco I., David E., Gilad Y., Lauriola M., Rotkopf R., Kimchi A., Haga Y., Tsutsumi Y., Mirabeau O., Surdez D., Zinovyev A., Delattre O., Kovar H., Amit I. & Yarden Y. (2019) Cell Reports
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Manfred Eigen (1927-2019)

Pecht I. & Jovin T. (2019) Science
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High cGMP and low PDE3A activity are associated with oocyte meiotic incompetence

Gershon E., Maimon I., Galiani D., Elbaz M., Karasenti S. & Dekel N. (2019) Cell Cycle
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Immunological tolerance-t cells

Goldfarb Y., Peligero-Cruz C. & Abramson J. (2019) , The Autoimmune Diseases
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Dynamic Aspects of the Immunoglobulin Structure

Nezlin R. (2019) Immunological Investigations
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Demystifying the extracellular matrix and its proteolytic remodeling in the brain: structural and functional insights

Krishnaswamy V. R., Benbenishty A., Blinder P. & Sagi I. (2019) Cellular and Molecular Life Sciences
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Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1

Khor B., Conway K. L., Omar A. S., Biton M., Haber A. L., Rogel N., Baxt L. A., Begun J., Kuballa P., Gagnon J. D., Lassen K. G., Regev A. & Xavier R. J. (2019) Journal of Immunology
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Beta-like importins mediate the nuclear translocation of MAPKs

Zehorai E. & Seger R. (2019) Cellular Physiology and Biochemistry
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Differential Modulation of Platelet Adhesion and Spreading by Adhesive Ligand Density

Zarka R., Horev M. B., Volberg T., Neubauer S., Kessler H., Spatz J. P. & Geiger B. (2019) Nano Letters
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Veto cells for safer nonmyeloablative haploidentical HSCT and CAR T cell therapy

Reisner Y. & Or-Geva N. (2019) Seminars in Hematology
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Orientation of Oligopeptides in Self-Assembled Monolayers Inferred from Infrared Reflection-Absorption Spectroscopy

Schweitzer-Stenner R., Pecht I. & Guo C. (2019) Journal of Physical Chemistry B
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Mitochondrial plasticity in cell fate regulation

Bahat A. & Gross A. (2019) Journal of Biological Chemistry
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The EXPANDER Integrated Platform for Transcriptome Analysis

Hait T. A., Maron-Katz A., Sagir D., Amar D., Ulitsky I., Linhart C., Tanay A., Sharan R., Shiloh Y., Elkon R. & Shamir R. (2019) Journal of Molecular Biology
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Can immunization with Bacillus Calmette-Guerin (BCG) protect against Alzheimer's disease?

Gofrit O. N., Bercovier H., Klein B. Y., Cohen I. R., Ben-Hur T. & Greenblatt C. L. (2019) Medical Hypotheses
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Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer

Silberman A., Goldman O., Assayag O. B., Jacob A., Rabinovich S., Adler L., Lee J. S., Keshet R., Sarver A., Frug J., Stettner N., Galai S., Persi E., Halpern K. B., Zaltsman-Amir Y., Pode-Shakked B., Eilam R., Anikster Y., Nagamani S. C. S., Ulitsky I., Ruppin E. & Erez A. (2019) Cancer Research
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Stable contacts of naive CD4 T cells with migratory dendritic cells are ICAM-1-dependent but dispensable for proliferation in vivo

Kozlovski S., Atrakchi O., Feigelson S. W., Shulman Z. & Alon R. (2019) Cell Adhesion & Migration
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