From Single cells to Microbial Collectives

We develop algorithms and utilize single cell genomics for studying the organization and function of immune cells in a tissue

How diverse posttranscriptional modifications regulate the fate of mRNA

Environmental microbes and their response to human-made pollution

Developing experimental and computational approaches for multiplexed imaging of clinical specimens to uncover tumor-immune interactions

Personalized medicine using machine learning applied to genomic and clinical data

Biological circuits: design, function and evolution • Regulatory genome: transcription, replication and the chromatin as a communication platform • Developmental patterning: morphogen gradients, scaling, robustness