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Weizmann Institute of Science Department of Molecular Cell Biology
Uri Alon Lab
Design Principles in Biology
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Systems Biology 2018

  • Lecture 1 - Basic concepts (27/3/18)

     

    • Exercise 1 (solution)
  • Lecture 2 - Auto-regulation , a network motif (10/4/18)

     

    • Exercise 2 (data needed for the exercise - coliinterfullvec.txt)
  • Lecture 3 Part a - Feed Forward Loops (17/4/18)
  • Lecture 3 - Part b - Feed Forward Loop (17/4/18)
  • Lecture 4 A - Temporal Order, Global Structure, and Memory (24/4/18)
  • Lecture 4 b - Temporal Order, Global Structure, and Memory (24/4/18)
    • Exercise 3
  • Lecture 5 a - Robustness using bifunctional components (1/5/18)
  • Lecture 5 B - Robustness using bifunctional components (1/5/18)
    • Lecture notes 
  • Lecture 6 a - Robustness in bacterial chemotaxis (8/5/18)
  • Lecture 6 B - Robustness in bacterial chemotaxis (8/5/18)
    • Lecture Notes - Robustness in bacterial chemotaxis
    • Exercise 4
  • Lecture 7  part A - Fold Change Detection
  • Lecture 7  part B - Fold Change Detection
    • Lecture Notes
  • Lecture 8  part A -  Dynamic Compensation in Physiological Circuits
  • Lecture 8  part B -  Dynamic Compensation in Physiological Circuits
  • Lecture 8  part C -  Dynamic Compensation in Physiological Circuits
    • Lecture Notes
    • Exercise 5
  • Lecture 9 - How to build a Biological Oscillator
    • Lecture Notes
  • Lecture 10 - Optimality in Biological Circuits
    • Lecture Notes
    • Exercise 6
  • Lecture 11 - Evolution and Multi-Objective Optimality
  • Lecture 12 - Modularity
Weizmann Institute of Science Department of Molecular Cell Biology
Uri Alon Lab
Design Principles in Biology