Events

Seminar for PhD thesis defense

Time11:30 - 11:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Tslil Braun

Seminar for PhD thesis defense

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Biologically Inspired Engineering for Probing, Programming and Recoding Organisms

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Farren J. Isaacs

Abstract

A defining challenge in synthetic biology is the development of high-throughput and automated methodologies for precise design and engineering of cells. To address these challenges, we develop multiplex genome engineering technologies for versatile genome modification and evolution of bacterial and eukaryotic cells. We use these technologies to create genetic variants to reveal a causal understanding of complex phenotypes as well as engineer pathways and recode genomes. These Genomically Recoded Organisms (GROs) contain alternative genetic codes, in which codons have been eliminated from the genome of E. coli. GROs exhibit improved properties for incorporation of nonstandard amino acids that expand the chemical diversity of proteins or polymers, establish genetic isolation and multi-virus resistance, and enable the engineering of GROs to depend on synthetic amino acids for robust biocontainment strategies. We have also developed new computational-experimental technologies – computer aided design of synthetic genetic elements (CAD-SGE) – that permits the redesign, expression, and mobilization of biosynthetic pathways in diverse organisms for the discovery of new metabolites. This work increases the toolbox for genomic and cellular engineering with broad applications for new classes of enzymes, materials, and therapeutics.

Seminar for MSc thesis defense

Time15:00 - 15:00

LecturerShani Ravid

Seminar for PhD thesis defense

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRan Shachar

Friction and Time Measurement: How the Invention of the Pendulum Made Clocks Much More Accurate

Time14:00 - 15:00

LocationGerhard M.J. Schmidt Lecture Hall

LecturerPro. Michael Nosonovsky

Special Guest Seminar with Prof. Eugene V. Koonin

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eugene V. Koonin

Abstract

Viruses and virus-like mobile genetic elements are ubiquitous parasites (and sometime symbionts) of all cellular life forms and the most abundant biological entities on earth. The recent, unprecedented advances of comparative genomics and metagenomics have led to the discovery of diverse novel groups of viruses and a rapid expansion of the chartered region of the virosphere. These discoveries provide for a vastly improved understanding of the evolutionary relationships within the virosphere. Arguably, we are approaching the point when the global architecture of the virus world can be outlined in its entirety, and the key evolutionary events in each of its domains can be reconstructed. I will present such an outline of the global organization of the virosphere and the corresponding megataxonomy, including 6 distinct virus realms, that has been recently approved by the International Committee on Taxonomy of Viruses, as well as some new candidates. The expansion of the prokaryotic virosphere that is being shown to include many groups of viruses, particularly, those with RNA genomes, previously thought to be eukaryote-specific, will be emphasized. I will further discuss the position of viruses within the wider space of replicators and the recent dramatic expansion of the “alternative virosphere” that includes viroids and diverse viroid-like viruses that seem to have evolved on multiple, independent occasions.

Seminar for PhD thesis defense

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerGabriela Lobinska

Seminar for PhD thesis defense

Time10:00 - 11:00

LocationThe David Lopatie Hall of Graduate Studies

LecturerAlejandro Aguilera Castrejon

Seminar for PhD thesis defense

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerYehuda-Matan Danino

Seminar thesis defense

Time10:00 - 11:00

LecturerJacob Hanna lab,Max Rose

Special Guest Seminar with Prof. Ziv Bar-Joseph

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ziv Bar-Joseph

Abstract

Abstract: While research institutions including Weizmann are leading the way in cutting edge work in omics data analysis and modeling, biotechs and pharma are very advanced, and in some cases leading, in areas related to molecular design and clinical data analysis. I have been leading the AI / ML work for R&D at one of the largest pharma companies for almost two years and will share some of the methods we have been developing and using to address computational challenges across all stages of the drug discovery and development process. I Will also try to share some of the lessons I have learned over this period.

Special Guest Seminar with Prof. Yegor Bazykin

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Yegor Bazykin

Seminar for PhD thesis defense

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerSarit Meril

Seminar for PhD thesis defense

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAvigail Stokar Avihail

Special Guest Seminar with Prof. Judith Frydman

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Judith Frydman

Special Guest seminar with Dr. Raul Andino

Time14:30 - 15:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Raul Andino

Seminar for PhD thesis defense

Time16:00 - 17:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerOffir Lupo

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special guest Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Anton Zilman

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special guest seminar with Nadav Ahituv

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Nadav Ahituv,Sandi Britton

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar

Time15:00 - 16:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Alexander Meissner & Prof. Paul Tesar

Special Guest Seminar

Time15:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Alexander Meissner & Prof. Paul Tesar

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Systems Biology Seminar

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

MSc Thesis Defense

Time14:00 - 14:00

LecturerElisheva Berent-Barzel

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Leonid Chernomordik

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Danielle Grotjahn

Special Guest Seminar

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Jennifer Lippincott-Schwartz

Seminar for PhD Thesis Defense

Time09:30 - 09:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerYaara Finkel

Seminar for thesis defense with Yaara Finkel

Time09:30 - 10:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerSandi Britton,Yaara Finkel

Seminar for MSc thesis defense

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerSivan Arad

Special Guest Seminar

Time15:30 - 16:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ritsuko K. Pooh

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Seminar for MSc Thesis Defense

Time15:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerLior Peer

Seminar for Thesis Defense with Raman Singh

Time09:00 - 10:00

LocationNella and Leon Benoziyo Building for Biological Sciences

LecturerRaman Singh,Sandi Britton

Seminar for Thesis Defense with Svetlana Markman

Time14:30 - 15:30

LocationGerhard M.J. Schmidt Lecture Hall

Lecturer,Sandi Britton

Systems Biology Seminar 2022-2023

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Yaron Orenstein

Seminar for Thesis defense

Time15:30 - 16:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNoa Aharon-Hefetz

Special Guest Seminar

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Florian Wilfling

Special guest seminar, Dr Harry Burgess

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Harry Burgess

Seminar for Thesis Defense of Adi Millman

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAdi Millman

Guest seminar with Prof. Utpal Banerjee

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Utpal Banerjee

Special guest semianr with Dr. Asaf Zviran

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Asaf Zviran

Abstract

Early detection of recurrence and monitoring of Molecular Residual Disease (MRD) post-surgery is critical for clinical decision-making to tailor personalized treatments across solid cancers. C2i Genomics has developed an ultra-sensitive whole-genome ctDNA test, allowing extremely accurate and sensitive monitoring of patients with solid tumors. Here we present results from applying whole-genome sequencing (WGS) and identification of ctDNA across a variety of adult and pediatric solid tumors. We integrate a genome-wide mutation and copy number monitoring approach coupled with advanced signal processing and Artificial Intelligence (AI) for measuring the tumor load from low-input blood samples (~1mL of plasma) with ultra-sensitive detection. The increased sensitivity allowed clinical detection of tumor fraction down to 5*10-5 and recurrence detection sensitivity achieving >65% at the first two months after definitive treatment, enabling earlier clinical intervention for high-risk patients.

Seminar for PhD thesis defense

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNir Cohen

Special Guest Seminar

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. David Reich

Seminar for PhD thesis defense

Time15:00 - 16:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerGal Chaim Nuta

Special guest semianr with Prof. Jin Billy Li

Time13:15 - 13:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerJin Billy Li

Special Guest Seminar with Prof. Hervé Le Hir

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Transcription Drive Development Minisymposium

Time10:30 - 15:00

LocationDolfi and Lola Ebner Auditorium

Seminar for Thesis Defense

Time14:00 - 15:00

LecturerDr. Karin Broennimann

Molecular Genteics departmental retreat

Molecular Genetics Departmental seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerYehuda Danino & Tslil Braun

Contact Sandra.britton@weizmann.ac.il

Special guest seminar with Prof. Kent Søe

Time13:30 - 14:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

Seminar for PhD thesis defense

Time12:00 - 13:00

LecturerMira Rosenthal

Department of Molecular Genetics departmental seminar

Time13:00 - 14:00

LocationDolfi and Lola Ebner Auditorium

LecturerAssaf Biran

Special Guest Seminar

Time13:00 - 14:00

LecturerDr. Lilach Sheiner

Department of Molecular Genetics departmental seminar

Time13:00 - 14:00

LecturerYury Bykov and Oldak Bernardo

Azrieli Institute for Systems Biology, guest seminar with Ahmed H. Badran

Time17:00 - 18:00

LecturerAhmed H. Badran, PhD,The Scripps Research Institute,USA

Seminar for PhD thesis defense

Time13:30 - 13:30

LecturerSivan Kaminski Strauss

Seminar for PhD thesis defense

Time11:00 - 11:00

Guest seminar with Vered Shacham-Silverberg

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Vered Shacham-Silverberg

Seminar for PhD thesis defense

Time13:15 - 13:15

LecturerTom Shani

Molecular Genetics departmental seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAmit Kahana (lancet lab) Gabriela Lobinska (Pilpel lab)

Special Guest seminar

Time11:00 - 11:00

LecturerProf. Gianni Liti

“Computational Methods for Super-resolution Single Molecule Localization Microscopy”

Time11:30 - 12:30

LecturerDr. Ismail M. Khater

Special Guest Seminar

Time10:00 - 11:00

LecturerDr. Eyal Karzbrun

Seminar for Thesis Defense,

Time09:00 - 10:00

LecturerLia Heinemann Yerushalmi

Seminar for PhD thesis defense

Time10:00 - 10:00

LecturerHagai Marmor - Kollet

Special seminar with Dr. Yaara Oren

Time15:00 - 16:00

LecturerDr. Yaara Oren

Abstract

Despite favorable initial response to therapy, a third of cancer patients will develop recurrent disease and succumb to it within five years of diagnosis. While there has been much progress in characterizing the pathways that contribute to stable genetic drug resistance, the mechanisms underlying early reversible resistance, also known as persisters-driven resistance, remain largely unknown. It has long been believed that persisters represent a subset of cells that happen to be non-proliferating at the time of treatment, and therefore can survive drugs that preferentially kill rapidly proliferating cells. However, in my talk I will describe a rare persister population which, despite not harboring any resistance-conferring mutation, can maintain proliferative capacity in the presence of drug. To study this rare, transiently-resistant, cycling persister population, we developed Watermelon, a high-complexity expressed barcode lentiviral library for simultaneous tracing of each cell’s clonal origin and proliferative and transcriptional states. We combine single cell transcriptomics with imaging and metabolomics to show that cycling and non-cycling persisters arise from different cell lineages with distinct transcriptional and metabolic programs. Finally, I will describe how by studying persister cells we can gain critical insights on cellular memory, fate, and evolution, which can guide the development of better anti-cancer treatments.

Special guest seminar with Dr. Inna Ricardo-Lax

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Inna Ricardo-Lax

Molecular Genetics departmental seminar with Omri Gilhar

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerOmri Gilhar

Molecular Genetics Departmental seminar with Nancy Yacovzada

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNancy Yacovzada

Molecular Genetics Departmental seminar with Daoud Sheiban

Time13:00 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDaoud Sheiban

Molecular Genetics Departmental seminar with Yotam David

Time13:00 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerYotam David

Molecular Genetics Departmental seminar with Sveta Markman

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Departmental seminar with Michal Schwartz

Time13:00 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Michal Schwartz

Seminar for PhD thesis defense - Aya Shkedy

Time12:00 - 13:00

Departmental Seminar with Lena Sapoznikov

Time13:00 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerLena Sapoznikov

Seminar for Thesis defense of Gat Krieger

Time13:30 - 14:30

LecturerGat Krieger

ILASOL 2021 Conference

LocationArthur and Rochelle Belfer Building for Biomedical Research

Contact amit.kahana@weizmann.ac.il

Seminar for PhD thesis defense - Moran Shalev

Time11:00 - 11:00

LecturerMoran Shalev

Molecular Genetics Departmental Seminar

Time13:00 - 13:30

LecturerNadav Goldberg

Seminar for PhD thesis defense

Time15:00 - 16:00

LecturerGal Ofir

Molecular Genetics Departmental Seminar

Time13:00 - 13:30

LecturerSivan Kaminski

Seminar for MSc thesis defense - Nadav Goldberg

Time10:00 - 11:00

LecturerNadav Goldberg

Department of Molecular Genetics departmental seminar

Time13:00 - 13:30

LecturerNir Cohen

Department of Molecular Genetics departmental seminar

Time13:00 - 13:30

LecturerSarah Rubin

Department of Molecular Genetics department seminar

Time13:00 - 13:30

LecturerJohannes Auth

Seminar for PhD thesis defense - Lior Lasman

Time10:00 - 11:00

LecturerLior Lasman

Molecular Genetics Departmental Seminar

Time13:00 - 13:00

LecturerTamar Gera

Seminar for PhD thesis defense - Revital Ravid

Time10:00 - 10:00

LecturerRevital Ravid

PhD Thesis defense - Orel Mizrahi

Time11:00 - 12:00

LecturerOrel Mizrahi

Website https://weizmann.zoom.us/j/98492519654?pwd=a0lNd1ROc0kwTXBaUnI4M0R2aENOdz09

Departmental seminar with Anna Uzonyi

Time13:00 - 13:30

Website https://weizmann.zoom.us/j/96260232296?pwd=ck16LzU2SjdWNU80eFZRWUNTbXpPUT09

Departmental seminar with Nelly Frenkel

Time13:00 - 13:30

LecturerDr. Nelly Frenkel

Special zoom joint guest seminar

Time11:00 - 12:00

LecturerDr. Anat Florentin

Special Guest Seminar - David Gokhman

Time10:00 - 10:00

LecturerDr. David Gokhman

Molecular Genetics Departmental Seminar with Yaara Finkel

Time13:00 - 13:00

LecturerYaara Finkel

Seminar for thesis definse of Dvir Schirman

Time11:00 - 11:00

LecturerDvir Schirman

Seminar for thesis defense, Moria Weiss

Time10:00 - 11:00

LecturerMoria Weiss

Seminar for thesis defense - Shiri Kult

Time16:00 - 16:00

LecturerShiri Kult

Molecular Genetics departmental seminar with Sharon Ben-Hur

Time13:00 - 13:00

LocationDolfi and Lola Ebner Auditorium

LecturerSharon Ben-Hur

Molecular Genetics departmental seminar with Orel Mizrahi

Time13:00 - 13:00

LocationDolfi and Lola Ebner Auditorium

LecturerOrel Mizrahi

Seminar for thesis defense

Time13:00 - 14:00

LecturerDr. Nelly Frenkel

seminar for thesis defense with Jonathan Bayerl

Time13:00 - 13:00

LecturerJonathan Bayerl

Special guest seminar with Dr. Yosef Kaplan Dor

Time16:00 - 16:00

LecturerDr. Yosef Dor Kaplan

Abstract

Sleep is ubiquitous in the animal kingdom, but its function has been a mystery. Besides its importance for the brain, sleep appears to play an essential physiological role, emphasized by the fact that severe sleep loss can be lethal. The cause of this lethality was unknown. We found that extreme sleep deprivation results in high levels of reactive oxygen species (ROS) that trigger oxidative stress specifically in the gut of flies and mice. Using flies, we show that neutralization of intestinal ROS prevents premature death of sleep-deprived animals, suggesting a causal link between ROS accumulation in the gut and lethality upon sleep loss. What may explain the observed phenomena? Could it teach us about the normal, daily function of sleep? In the second part of my talk, I will present our current attempts and preliminary data aiming at answering these questions.

Seminar for thesis defense with Unnikannan CP

Time10:00 - 10:00

LecturerUnnikannan CP

Molecular Genetics departmental seminar

Time13:00 - 13:00

Molecular Genetics Departmental seminar

Time13:00 - 13:00

LecturerHagai Marmor

Department seminar with Batsheva Rozman

Time13:00 - 14:00

LecturerBatsheva Rozman

Braginsky Center for the Interface between Science and the Humanities zoom lecture with Prof. Mario Livio

Time16:00 - 17:00

LecturerProf. Mario Livio

Abstract

A fresh biography of Galileo Galilei which puts his scientific discoveries in context. Disturbed by rampant science denial in America—and around the world—that has only intensified in recent years, I began researching the life, ideas, and actions of this brilliant man who encountered similar pressures centuries ago. The result is a biography filled with lessons relevant for today—whether with respect to trusting the advice given by scientists in relation to COVID-19, the reality of climate change, the efficacy of vaccines, or the teaching of creationist theories in schools. I will discuss these topics in this talk.

Special zoom Seminar with Dr. Dvir Gur

Time10:00 - 11:00

LecturerDr. Dvir Gur

Special zoom seminar with Dr. Dan Landau

Time16:00 - 17:00

LecturerDr. Dan Landau

Departmental Seminar by Mira Rosenthal & Lia Yerushalmi

Time13:00 - 14:00

Departmental seminar by Miri Shnayder

Time13:00 - 13:45

Developmental Club Series 2019-20-cancelled

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ori Avinoam

Departmental Seminar by Romano Strobelt

Time13:00 - 13:45

Departmental Seminar by Aya Shkedy

Time13:00 - 14:00

Developmental Club Series 2019-20 - cancelled

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eli Arama

Departmental Seminar by Kamalesh Kumari

Time13:00 - 13:45

Departmental seminar by Aude Bernheim

Time13:00 - 13:45

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Gil Levkowitz

POSTPONED: Braginsky Center for the interface between the Science and the Humanities

Time14:00 - 15:00

LocationDolfi and Lola Ebner Auditorium

LecturerProf. Menachem Fisch

Departmental Seminar by Daria Amiad-Pavlov

Time13:00 - 14:00

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Yonatan Stelzer

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Efrat Shema

Developmental Club Series

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Amir Sapir

Departmental Seminar by Lihi Ben Reuven & Miri Shnayder

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eran Hornstein

Departmental Seminar by Nir Cohen & TBD

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Decoding transcriptional regulation in Drosophila

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Alexander Stark

Contact igor.ulitsky@weizmann.ac.il

TBA - cancelled

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRuth Sperling

POSTPONED: Departmental Seminar by Daria Amiad-Pavlov & Lia Yerushalmi

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

POSTPONED: Developmental Club Series with Elazar Zelzer

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Elazar Zelzer

Seminar for Thesis Defense- Roni Winkler

Time11:30 - 12:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRoni Winkler

Departmental Seminar by Gat Krieger & Kamalesh Kumari

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Azrieli Institute for Systems Biology

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Dieter Ebert

Departmental Seminar by Rami Tshuva & Dvir Schirman

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Molecular Genetics special guest seminar

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Gilad Barnea

Abstract

I will present trans-Tango, a new technique for anterograde transsynaptic circuit tracing and manipulation that we have established in fruit flies. At the core of trans-Tango is a synthetic signaling pathway that is introduced into all neurons in the animal. This pathway converts receptor activation at the cell-surface into reporter expression through site-specific proteolysis. Specific labeling is achieved by presenting a tethered ligand at the synapses of genetically defined neurons, thereby activating the pathway in their postsynaptic partners. Activation of the pathway culminates in expression of a reporter that can be visualized. Because our system is modular, it can be easily adapted to experiments in which the properties of specific circuits are modified and the functional consequences are analyzed. We first validated trans-Tango in the Drosophila olfactory system and then implemented it in the gustatory system, where projections beyond the firstorder receptor neurons are not well characterized. We identified second-order neurons within the sweet and bitter circuits and revealed that they target brain areas involved in neuromodulation with similar but distinct projection patterns. I will also present experiments in which we use trans-Tango in functional analysis of the gustatory circuits. Using our studies in flies as proof of concept, we are currently establishing an equivalent technique for labeling circuits in vertebrate models, such as mice and zebrafish. These experiments establish trans-Tango as a flexible platform for comprehensive transsynaptic analysis of neural circuits.

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Talila Volk

Departmental Seminar by Sagie Brodsky & Noa Novershtern

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Seminar for thesis defense - Karen Fridman Talmon

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerKaren Fridman Talmon

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Takashi Kawashima

Special Guest Seminar with Prof. Detlef Wiegel

Time11:30 - 12:30

LocationNella and Leon Benoziyo Building for Biological Sciences

LecturerProf. Detlef Wiegel

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Meital Oren

Departmental Seminar - Molecular Genetics Dept.

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Oren Schuldiner

Department of Molecular Genetics Special guest seminar

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Francesca Bartolini

Braginsky Center for the Interface between the Sciences and the Humanities

Time11:00 - 11:00

LocationDolfi and Lola Ebner Auditorium

LecturerProf. Oren Harman

Departmental Seminar - Molecular Genetics Dept.

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar with Dr, Michael E. Ward

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Michael E. Ward

Developmental Club Series 2019-20

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ido Amit

Departmental Seminar - Molecular Genetics Dept.

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar with Dr. Arbel Harpak

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Arbel Harpak

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Amnon Sharir, DVM, PhD.

Special Guest Seminar with Dr. Onn Brandman

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Onn Brandman

The Braginsky Center for the Interface between the Sciences and the Humanities

Time11:00 - 11:00

LocationGerhard M.J. Schmidt Lecture Hall

LecturerProf. Reviel Netz

Seminar for thesis defense, Nofar Mor

Time15:00 - 16:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNofar Mor

Special guest seminar with Moran Dvela-Levitt

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerMoran Dvela-Levitt

Abstract

Protein homeostasis is critical for cellular function and survival. Dysregulation of the cellular protein homeostasis can lead to a build-up of misfolded proteins and facilitate the manifestation of a variety of pathological disorders including neurodegeneration, cancer and inflammation. Where and how the misfolded proteins accumulate, however, has remained a mystery. In studying MUC1 kidney disease (a rare kidney disorder), we have found that some of these pathologies may share a single, previously unrecognized cellular mechanism: a jam at a specific step in the secretory pathway involving a cargo receptor called TMED9. A small molecule called BRD4780 can break the jam and restore cells to normal function, providing a promising potential for therapeutic developments.

Seminar for thesis defense, Maya Voichek

Time15:00 - 16:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerMaya Voichek

Developmental Club Series 2019-20

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yaron Antebi

Special Guest Seminar

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Orly Laufman

Departmental Seminar - Molecular Genetics Dept.

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Developmental Club Series 2019-20

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Avraham Yaron

Seminar for thesis Defense - Zohar Erez

Time15:30 - 15:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerZohar Erez

Special Guest Seminar

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNevan Krogan

Departmental Seminar - Molecular Genetics Dept.

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Braginsky Center for the Interface between the Sciences and the Humanities, special guest lecture with Daniel Matt

Time16:00 - 17:00

LocationGerhard M.J. Schmidt Lecture Hall

LecturerProf. Daniel Matt

Seminar for thesis defense Naama Dekel

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNaama Dekel

Special Guest Seminar

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Peter Tsvetkov

Special Guest Seminar with Anat Zimmer

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAnat Zimmer

Abstract

It is a challenge to answer questions like: why some people develop a disease, react to a specific treatment and/or develop severe side-effects while others don’t. In order to explain these occurrences, one has to take a holistic approach and study the body physiology from a systems level perspective. Longitudinal multi-omics measurements together with genetics, on a large population, can serve such a purpose and help in predicting, reasoning, and preventing diseases. In partnership with Arivale Inc., we have developed infrastructure to collect longitudinal Personalized Dense Dynamic Data clouds (PD3 clouds) on thousands of individuals, which include genetics and longitudinal measurements of clinical labs, microbiome, metabolome, proteome, and self-reported data. The value of these extremely high-dimensional data clouds is clear; however, it also comprises a challenge in data analysis and interpretation. One way to reduce data dimensionality is called Pareto Task Inference (PARTI, Hart et al. 2015). We used this method to analyze the clinical labs and found that the data falls on a significant tetrahedron. The 4 vertices are archetypes that specialize in a certain task. Using all other datatypes, we identified enriched traits next to every archetype and revealed the underline tradeoffs that shape the data. This distinctive analysis uncovers unexpected relationships between datasets such as metabolomics, proteomics and clinical labs, and helps in interconnecting the different datatypes to characterize different states of human health.

Special Guest Seminar with Dr. Johnathan Cooper-Knock

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Johnathan Cooper-Knock

Special Guest Seminar with Ophir Shalem

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerOphir Shalem,Ph.D

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ori Avinoam

Special Guest Seminar

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerClaire Thomas

Shoulder Injury Seminar Department of Molecular Genetics

Time09:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerPh.D,Prof. Louis J. Soslowsky

Special Guest Seminar

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yael Weiss

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Amrutha Swaminathan

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRuth Barshir

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Nadav Ahituv

Developmental Club

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eran Hornstein

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAldema Sas Chen

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Efrat Shema

Developmental Club Series 2018-2019

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Efrat Shema

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerHarsh Maan

Developmental Club

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Shalev Itzkovitz

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerYaara Finkel

Contact evi@weizmann.ac.il

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerQihui Hou

Contact evi@weizmann.ac.il

Polymerizing the Fiber Between Bacterial Biofilms and Human Amyloids

Time10:00 - 11:00

LocationNella and Leon Benoziyo Building for Biological Sciences

LecturerProf. Matthew Chapman

Molecular Genetics Departmental Retreat

Cross regulation between the apoptotic cascade and the unfolded protein response

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAvi Ashkenazi

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerHagai Marmor

Contact evi@weizmann.ac.il

Developmental Club Series 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerOphir Klein

Seminar for thesis defense

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNeta Felsenthal

Contact evi@weizmann.ac.il

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Benny Shilo

Contact evi@weizmann.ac.il

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerInes Castro

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Yonatan Stelzer

Special Guest Seminar with Dr. Markus Mund

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Markus Mund

Special Guest Seminar with prof. Johannes Herrmann

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Dr. Johannes Herrmann

Special guest seminar

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Andrea Pauli

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Andrea Pauli

Department of Molecular Genetics seminar for thesis defense

Time13:00 - 13:00

LecturerYael Cohen Sharir

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eran Hornstein

Developmental Club Series 2018-2019

Time10:00 - 11:00

LocationCamelia Botnar Building

LecturerHannes Buelow

Department of Molecular Genetics seminar for thesis defense

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerEyal Metzl Raz

Department of Molecular Genetics seminar for thesis defense

Time09:00 - 10:00

LecturerMarianna Riutin

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Talila Volk

Developmental Club Series 2018-2019

Time09:30 - 09:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerMeital Oren

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerEden Yifrach

Seminar for thesis defense

Time14:30 - 14:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerTzahi Noiman

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Oren Schuldiner

"Mechanisms of asymmetric cell division"

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Yves Barral

Molecular Genetics Departmental Seminars 2018-2019

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerMaayan Barnea

Special Guest Seminar with Prof. Meytal Landau

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Meytal Landau

Special Guest Seminar with Ariel Schwartz

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Ariel Schwartz

Abstract

Computational assignment of function to proteins with no known homologs is still an unsolved problem. We have created a novel, function-based approach to protein annotation and discovery called D-SPACE (Deep Semantic Protein Annotation Classification and Exploration), comprised of a multi-task, multi-label deep neural network trained on over 70 million proteins. Distinct from homology and motif-based methods, D-SPACE encodes proteins in high-dimensional representations (embeddings), allowing the accurate assignment of over 180,000 labels for 13 distinct tasks. The embedding representation enables fast searches for functionally related proteins, including homologs undetectable by traditional approaches. D-SPACE annotates all 109 million proteins in UniProt in under 35 hours on a single computer and searches the entirety of these in seconds. D-SPACE further quantifies the relative functional effect of mutations, facilitating rapid in-silico mutagenesis for protein engineering applications. D-SPACE incorporates protein annotation, search, and other exploratory efforts into a single cohesive model. We have recently extended this work from protein to DNA, enabling assignment of function to whole genomes and metagenomic contigs in seconds. Conserved genomic motifs as well as the functional impact of mutations in coding as well as non-coding genomic regions can be predicted directly from raw DNA sequence without the use of traditional comparative genomics approaches for motif detection, such as multiple sequence alignments, PSSMs, and profile HMMs.

Special Guest Seminar with Dan Bracha

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDan Bracha

Special Guest Seminar with Dr. Shai Carmi

Time11:30 - 11:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Shai Carmi

Abstract

In this talk, I will review recent work by myself and others on Jewish population and medical genetics, focusing on Ashkenazi Jews (AJ). I will describe the mixture events of AJ in Europe, the founder event they have experienced in the late Middle Ages, and their connections to ancient populations of the Levant. I will then describe large-scale genomic databases that we have recently generated for AJ, and the opportunities they open in medical genetics given the unique AJ demographic history. I will describe a few medical genetics projects including carrier screening, genome-wide association studies of microbiome composition and other traits, and preimplantation genetic diagnosis.

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerJulie Tai

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerBruno Lemaitre

“The Foreign within: Drosophilia-Spiroplasma interaction as a model of insect endosymbiosis”

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerBruno Lemaitre

Large-scale genomic investigations of psychiatric and neurodevelopmental disorders and their connection to somatic disease in the Danish population

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRon Nudel

Contact Simon.Fishilevich@weizmann.ac.il

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAdi Millman

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAdi Millman

Smaller is better

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Klaus Herick

Contact Moran.Shalev@weizmann.ac.il

Developmental Club Series 2018-19

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eldad Tzahor

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerInna Averbukh

Joint mini-symposium

Time11:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Joel Richter

Developmental Club Series 2018-19

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Elazar Zelzer

Developmental Club Series 2018-2019, special guest seminar

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Naihe Jing

Abstract

During postimplantation development of the mouse embryo, descendants of the inner cell mass cells in the early epiblast transit from the naïve pluripotent state to the primed pluripotent state. Concurrent with the transition of the pluripotency states is the specification of cell lineages and formation of germ layers in the embryos that serves as the blueprint for embryogenesis. Fate mapping and lineage analysis studies have revealed that cells in different regions of the germ layers acquire location-specific cell fates during gastrulation. The regionalization of cell fates heralding the formation of the basic body plan is conserved in vertebrate embryos at a common phylotypic stage of development. Knowledge of the molecular regulation that underpins the lineage specification and tissue patterning is instrumental for understanding embryonic programming and stem cell-based translational study. However, a genome-wide molecular annotation of lineage segregation and tissue architecture of post-implantation embryo has yet to be undertaken. Here, we reported a spatially resolved transcriptome of cell populations at defined positions in the germ layers over the period of pre- to late gastrulation development. This spatio-temporal transcriptome provides high resolution digitized in situ gene expression profiles and defines the molecular attribute of the genealogy of lineages and continuum of pluripotency states in time and space. The transcriptome further identifies the networks of molecular determinants that drive lineage specification and tissue patterning in the early postimplantation mouse embryo.

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerTzahi Gabzi

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Nathan Lawson

Department of Molecular Genetics seminar for thesis defense

Time13:30 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRivi Halimi

Nuclear Genome Nanostructure Imaging at Single Molecule Resolution

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Christoph Cremer

Abstract

Super-resolution fluorescence microscopy allows quantitative studies of nuclear genome organization on the nanoscale1. Here we report on results obtained by single molecule localization microscopy (SMLM). SMLM has made possible to explore chromatin nanostructure down to the imaging of single histones, of short oligosequences, or single DNA sites; presently, an intranuclear optical resolution down to the 5 nm range has been achieved. Applying a novel SMLM technique (fBALM)2, the DNA distribution across entire nuclei at nanoscale resolution was quantitatively determined, localizing in individual nuclear optical sections up to ~4 million individual DNA bound single fluorophore molecule positions, corresponding to about one position per nucleosome. Intensity profile analyses of the intranuclear DNA distributions indicated sharp transitions between high-density domains and low-density compartments, with differences up to almost two orders of magnitude; compacted regions had a minimum diameter down to ca. 50 nm diameter. In contrast to these results, conventional resolution imaging of the same nuclear sites indicated only small differences in the compaction of different regions, combined with very smooth density transitions. Taken together, the quantitative compaction estimates support models of a nuclear organization based on highly compartmentalized chromatin nanostructures3.

Special Guest Seminar

Time10:00 - 10:00

LocationNella and Leon Benoziyo Building for Biological Sciences

LecturerDr. Nadav Sharon

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Molecular Genetics Departmental Seminars 2018-2019

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Special Guest Seminar

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eugene Rosenberg

Developmental Club Series 2018-2019

Time10:00 - 10:00

LocationCamelia Botnar Building

LecturerProf. Karina Yaniv

Seminar for thesis defense

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerUri Weill

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eli Arama

Department of Molecular Genetics seminar for thesis defense

Time15:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDoreen Ben-Zvi

Molecular Genetics Departmental Seminars 2017-2018

Time13:15 - 13:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Karin Broennimann

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerLihi Ben-Reuven

Special Guest Seminar

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNava Segev

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ori Avinoam

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRonit Suissa

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerCarmine Settembre, PhD

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNoa Dahan

Contrary to Dogma: Tau is not a stabilizer of microtubules in the axon

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Peter W. Baas

Building the pathway for motion vision

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Claude Desplan

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Shalev Itzkovitz

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Jerome Gros

Accelerating bio discovery with machine learning

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerPhilip Nelson

Abstract

Google Accelerated Sciences is a translational research team that brings Google's technological expertise to the scientific community. Recent advances in machine learning have delivered incredible results in consumer applications (e.g. photo recognition, language translation), and is now beginning to play an important role in life sciences. Taking examples from active collaborations in the biochemical, biological, and biomedical fields, I will focus on how our team transforms science problems into data problems and applies Google's scaled computation, data-driven engineering, and machine learning to accelerate discovery.

Leica Biosystems

Time10:00 - 11:30

LocationRaoul and Graziella de Picciotto Building for Scientific and Technical Support

LecturerDr. Dorothee Lasrich

Cyagen technologies

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Matthew Wheeler

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRoni Winkler

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. James Sharpe

Abstract

The vertebrate limb bud is a classical model system for developmental biology – with the advantage of having been studied for many decades. Despite this, and despite its relatively simple shape, a consensus model of its physical morphogenesis has not been reached. I will introduce our own hypothesis on limb bud morphogenesis – convergent-extension coupled with tissue growth – and contrast it to previous ideas. I will introduce a 3D dynamical model which captures this hypothesis (a Cellular Potts Model) and also discuss our ongoing improvements to these simulations.

Atlases of structure-function relationships in small motifs: the limits of modularity

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. James Sharpe

Abstract

Abstract: I will discuss our work on visualizing “topology atlases” which act as a map of possible circuit designs for small 3-node regulatory motifs. These can help in understanding the relationship between a circuit's structure and its function, but how is this relationship affected if the circuit must perform multiple distinct functions within the same organism? In particular, to what extent do multi‐functional circuits contain modules which reflect the different functions? We computationally surveyed a range of bi‐functional circuits which show no simple structural modularity: They can switch between two qualitatively distinct functions, while both functions depend on all genes of the circuit. Our analysis revealed two distinct classes: hybrid circuits which overlay two simpler mono‐functional sub‐circuits within their circuitry, and emergent circuits, which do not. In this second class, the bi‐functionality emerges from more complex designs which are not fully decomposable into distinct modules and are consequently less intuitive to predict or understand. These non‐intuitive emergent circuits are just as robust as their hybrid counterparts, and we therefore suggest that the common bias toward studying modular systems may hinder our understanding of real biological circuits. Relevant papers: 1. A spectrum of modularity in multi-functional gene circuits. Jiménez A, Cotterell J, Munteanu A, Sharpe J. (2017) Mol Syst Biol 13(4):925. doi: 10.15252/msb.20167347 http://msb.embopress.org/content/13/4/925 2. An atlas of gene regulatory networks reveals multiple three-gene mechanisms for interpreting morphogen gradients. Cotterell J, Sharpe J. (2010) Mol Syst Biol 6:425. doi: 10.1038/msb.2010.74 http://msb.embopress.org/content/6/1/425 Bio: James Sharpe was originally captivated by computer programming, but upon learning about the digital nature of the genetic code, chose to study Biology for his undergraduate degree at Oxford University (1988-1991). He then did his PhD on the genetic control of embryo development at NIMR, London (1992-1997) and in parallel started writing computer simulations of multicellular development. During his post-doc in Edinburgh, he began modelling the dynamics of limb development, and also invented a new optical imaging technology called Optical Projection Tomography (OPT), which is dedicated to imaging specimens too large for microscopy - tissues and organs. In 2006 he moved to Barcelona, becoming a senior group leader at the Centre for Genomic Regulation, and focusing on a systems biology approach to modelling limb development – combining experimentation with computer modelling. In this way the group demonstrated that the signalling proteins which pattern the fingers during embryogenesis, act as a Turing reaction-diffusion system. In 2011 he became the coordinator of the Systems Biology Program, and in 2017 was recruited to EMBL as Head of the new Barcelona outstation on Tissue Biology and Disease Modelling.

Molecular Genetics Departmental Seminar

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAvigail Stokar

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerBenny Shilo

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAlona keren-Paz

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRivi Halimi

Special Guest Seminar

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAvi Ashkenazi, PhD

Abstract

Precise protein folding by the endoplasmic reticulum (ER) supports homeostasis, while cumulative protein misfolding causes ER stress and promotes disease. The kinases PERK and IRE1 help orchestrate the unfolded protein response (UPR) to alleviate ER stress; however, if stress persists, the UPR activates apoptosis to eliminate the damaged cell. We have previously shown that PERK drives cell death via transcriptional up-regulation of the pro-apoptotic death receptor DR5; we further showed that IRE1—which harbors both kinase and RNase modules—blocks apoptosis through regulated IRE1-dependent mRNA decay (RIDD) of DR5 (Lu et al, Science 2014). Recently, we turned to investigate the paradoxical observation that under irresolvable ER stress PERK activity persists, while IRE1 function attenuates. We discovered that PERK governs the attenuation of IRE1, through a phosphatase called RNA polymerase II-associated protein 2 (RPAP2). RPAP2 reverses IRE1 phosphorylation, inhibiting IRE1 RNase activation. This disrupts IRE1-dependent generation of the cytoprotective transcription factor XBP1s and dampens ER-associated degradation of misfolded proteins. Furthermore, it inhibits RIDD, thereby licensing DR5-mediated caspase activation and apoptotic cell death. Thus, under excessive ER stress, PERK attenuates IRE1 via RPAP2 to abort failed adaptation and trigger an apoptotic cell fate.

Special Guest Seminar

Time11:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Avi Ashkenazi

Abstract

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerMichal Chapal

Barcoding evolution

Time13:00 - 13:00

LocationCamelia Botnar Building

LecturerProf. Dmitri Petrov

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRon Weiss

Department of Molecular Genetics seminar for thesis defense

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerLiraz Keidar

Mini-Symposium on Genome, Transcriptome and Proteome

Time14:30 - 16:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerEyal Metzl-Raz

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Daoud Sheban

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Orly Reiner

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Orly Reiner

Predator-prey interactions of nematophagous fungi and C. elegans

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yen-Ping Hsueh

Optimizations and trade-offs in cellular growth and survial

Time08:00 - 08:00

LocationThe David Lopatie Conference Centre

Website http://www.weizmann.ac.il/conferences/OTCGS2018/

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerLia Yerushalmi

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Eran Hornstein

Noncoding RNA in Health and Disease

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Nikolaus Rajewsky

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerShiran Maskit

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Gil Levkowitz

Functions and regulation of 3D genome organisation in development and disease

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Francois Spitz

Abstract

The complex hierarchy of three-dimensional patterns that characterize the 3D folding of mammalian chromosomes appears as an important element in controlling gene expression. At the megabase scale, chromosomes are partitioned into domains that define two main compartments, corresponding to transcriptionally active and inactive regions, respectively. Each compartment domain is itself composed of distinct domains characterized by increased self-interactions called topological domains (TADs). Recent high-resolution Hi-C approaches revealed a finer-scale organisation of the genome in smaller “contact domains”, often associated with loops linking specific points. At these different scales, the spatial organisation of the genome shows tight correlation with its chromatin structure and its transcriptional activity. However, while steady progress is being made in describing the 3D folding of the genome at increased resolution, the mechanisms that determine this folding, its dynamic properties and the functional implications of these emerging features are still poorly understood. We use advanced genome tagging and engineering strategies, as well as targeted inactivation of factors involved in chromosomal folding to unravel the elements and mechanisms that drive the folding of large loci in specific yet dynamic conformations and their influence on gene expression. Our recent results show that the complex patterns of vertebrate HiC maps result from the superimposition of two distinct mechanisms: 1) a cohesin-independent mechanism which brings together regions of similar chromatin states 2) a cohesin-dependent folding that associate different small compartments into TADs. Within TADS, we show as well that enhancers are not acting in a homogeneous manner, but that their influence is distributed in complex patterns, partially guided by the underlying structure. I will discuss the different implications of these findings for our views of genome organisation.

Molecular Genetics Special Guest Seminar

Time10:00 - 11:00

LecturerDr. Nicolas Plachta

Molecular Genetics Departmental Seminar

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerEran Yanowski

Frontiers in Systems Biology: Prof. Anshule Kundaje

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Anshule Kundaje

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerIdan Frumkin

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Talila Volk

Molecular Genetics Special Guest Seminar

Time14:00 - 15:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yoav Ram

Single cell analysis of rare events in cancer

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Arjun Raj

Perception and computation in cellular signaling pathways

Time13:30 - 13:30

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yaron Antebi

Molecular Genetics Departmental Seminar

Time13:15 - 13:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Dana Lorber

Special Guest Seminar

Time12:00 - 13:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerRavit Boger, MD

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerElla Preger-Ben Noon

Revealing the structural basis for membrane transport and GPCR signaling through atomic-level simulation

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ron Dror

Departmental Seminar

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerGal Nuta

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Gil Levkowitz

Frontiers in Systems Biology

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Mihaela Zavolan

Abstract

In yeast, the knock out of individual ribosomal protein (RP) genes leads to a wide range of life span phenotypes, some mutants having significantly increased, other significantly decreased life span. In this talk I would like to present our efforts in characterizing the regulation of mRNA translation in relation to cellular states, from yeast to man. I will describe our work on inferring determinants of protein synthesis rates in yeast, where we found that the Gcn4 transcription factor, which is induced in many conditions that enhance yeast lifespan (RP gene knockout, calorie restriction, mTOR inhibition) not only activates transcription of amino acid biosynthesis genes, but also represses protein biosynthesis. How much variation in RP expression is expected in human tissues has been largely unknown, but RP gene mutations have been described in association with hematological disorders. Through a comprehensive analysis of human RP mRNAs expression pattern across 28 tissues, over 300 primary cells and 16 tumor types, we identified many RPs which exhibit tissue-specific expression. In the hematopoietic system, a small number of RP genes, possible regulated by transcription factors with tissue-specific expression, unequivocally discriminate cells of distinct lineages and developmental stages. Different cancer types also show dysregulated expression of individual RPs, some RPs having a relative increase and other decrease in expression. Finally, I will discuss our efforts in mapping sites of snoRNA-guided RNA modifications.

Unexpected Adventures with Human Endogenous Retroviruses and Centromeres

Time14:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. David Markovitz

Accessing the genome: transcription factors as sensors and modifiers of chromatin

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Dirk Schubeler

(Re)Constructing the Vertebrate Neural Tube

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. James Briscoe

Developmental Club Series 2017-2018

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr.Meital Oren

Frontiers in Systems Biology: Prof. Jörg Vogel

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Molecular Genetics Departmental Seminars 2017-2018

Time13:15 - 13:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerNofar Mor

Population as Distributed Memory System

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Ehud Lamm

Abstract

We show how the distribution of skills or phenotypes in a population acts as collective memory or "distributed information store" serving individual so that individuals with varying innate abilities are able to attain the mature fully skilled phenotype. We show how information moves "in" and "out" of genomes, relative to this memory system, elucidating how evolution determines where best to store information. This question applies to understanding diverse biological systems in which individuals acquire capacities from the population, including immunity, the microbiome, and social learning. Using Agent Based Modeling we investigate how properties of the population and social aspects of the acquisition process affect the behavior of the system. We show that the genetic properties of the population react predictably to changes in population properties that affect selection pressures, without any group level selective processes. Specifically, parameter changes that make acquisition slower lead to skills becoming increasingly innate while changes in parameters that improve the results of acquisition (e.g., making acquisition reliant on abundant left-over tools) lead to an increased reliance on acquisition, all while the average phenotype remains constant. The dynamics we study contribute to understanding how individuals can evolve to become more or less reliant on social learning and cultural information, how this depends on population properties (e.g., group size), and how this manifests demographically. The more information stored externally, the stronger the selection pressure on traits that support acquisition. Finally, we contrast our model and the Baldwin Effect and relate out results to the study of the evolution of human social learning.

Molecular Genetics Departmental Seminars 2017-2018

Time13:15 - 13:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerModi Safra

Identification of Druggable and Redox vulnerabilities in a genetically defined cancer

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Liron Bar-Peled

When enhancers drive the wrong genes: Mechanisms and role in tumorigenesis

Time09:00 - 09:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Yotam Drier

"Coordination of microbial metabolism through metabolite-protein interactions”

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Uwe Sauer

Molecular Genetics Departmental Seminars 2017-2018

Time13:00 - 14:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDagan Segal

Epistasis, pleiotropy, the ruggedness of fitness landscape, and the Predictability of RNA virus evolution

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Santiago Elena

Developmental Club Series 2017-2018

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Efrat Shema

You say tomato, I say potato. Evolution of the genetic code in yeasts

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Ken Wolfe

Specificity and evolution of bacterial signaling proteins

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Michael Laub

Abstract

Protein-protein interactions are critical to the operation and functions of all cells. The specificity of these interactions is often dictated at the level of molecular recognition, meaning proteins have an intrinsic ability to discriminate cognate from non-cognate partners. Understanding precisely how this discrimination is accomplished remains a major problem, particularly for paralogous protein families in which the individual members share high sequence and structural similarity. Our work tackles this problem primarily in the context of two-component signal transduction systems, the predominant form of signaling in bacteria, and more recently with toxin-antitoxin systems, also found throughout the bacterial kingdom. I will describe our work using analyses of amino acid coevolution to pinpoint the molecular basis of specificity in these proteins. This work has enabled the rational rewiring of protein-protein interactions and signal transduction pathways. Additionally, these studies have driven efforts to systematically map sequence spaces and probe the selective pressures and constraints that govern the evolution of protein-protein interactions.

"A stress-Induced Hidden Secret of the Genetic Code"

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerProf. Hanna Engelberg-Kulka

Systems Biology innovative awards

Time09:00 - 09:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

Imaging how cells decide their fate, shape and position in the early mouse embryo

Time11:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Nicolas Plachta

Abstract

ABSTRACT During development, each cell must resolve its fate, shape and position. Revealing how these decisions are made is critical to understand how embryos form, yet their real time control in mammals is unknown. Because fixed specimens cannot capture in vivo cell dynamics, we use imaging technologies to study single cells directly in live mouse embryos. We recently combined fluorescence correlation spectroscopy and photoactivation to show how the transcription factors Oct4 and Sox2 bind to DNA to determine the first cell fates of the embryo. We also designed methods to study how cells regulate their mechanical properties, and how they reorganize their actin and microtubule cytoskeletons to establish the first forms of tissue architecture. We discovered a new class of filopodia which helps cells to polarize and achieve embryo compaction, a role for cortical tension in driving the formation of the pluripotent inner mass, and a new type of non-centrosomal microtubule organizing center (MTOC) directing intracellular transport and differentiation in the embryo.

The surprising expansion of the epigenetic regulatory repertoire in mammals

Time12:00 - 12:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Andrew Xiao, PhD

Studying human evolution using DNA methylation maps of Neanderthals

Time10:00 - 10:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. David Gokhman

Virology Club speacial guest seminar

Time12:15 - 12:15

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerDr. Osnat Tirosh

Developmental Club Series 2016-2017

Time10:00 - 11:00

LocationArthur and Rochelle Belfer Building for Biomedical Research

LecturerAlon Greenbaum