History of the Cellulosome
In the early 1980s, Raffi Lamed and I met at Tel Aviv University and commenced our work that led to the discovery of the cellulosome concept. Raffi had just completed postdoctoral tenures in the States and I was at the tail end of a postdoc at Tel Aviv University. Raffi approached me at the time with a description of how Clostridium thermocellum, an anaerobic thermophilic cellulolytic bacterium, bound very strongly to the cellulose substrate before it commences its degradation. We decided to study this phenomenon together.