Event

Our lab studies brain-wide dynamics underlying cognition using the mouse model. We train mice on many different behavioral tasks, each focusing on a different cognitive function such as sensory integration, working memory, learning, social interactions and more. As mice perform each task, we implement brain-wide imaging techniques to record neuronal population activity from as many brain areas as possible. Two mesoscale techniques used in the lab are wide-field imaging of the whole dorsal cortex and multi-fiber photometry to record from dozens of cortical and subcortical areas, also during freely moving behavior. I will show unpublished results from mice trained on different cognitive tasks and highlight critical subnetworks involved in each cognitive function. I will further show preliminary results from freely moving behaviors in mouse models for autism, schizophrenia and Alzheimer's. Our long-term goal is to obtain a brain-wide cognitive map that will aid in understanding cognition as a whole in both the healthy and the disordered brain.