Stress Linked Psychopathologies

Regev L, Neufeld A, Tsoory M, Kuperman Y, Getselter D, Chen A.
Prolonged and site-specific over-expression of corticotropin releasing factor reveals differential role for extended amygdala nuclei in emotional regulation. Mol. Psychiatry 6:714-728.

Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PAT, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW.
Urocortin 3 transgenic mice exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high fat diet. Diabetologia 54:2392-2403. [13]

Elliott E, Ezra-Nevo G, Regev L, Neufeld-Cohen A, Chen A.
Resilience to social stress coincides with functional DNA methylation of the CRF gene in adult mice. Nat Neurosci. 13:1351-1353. [201]

Neufeld-Cohen A, Tsoory M, Evans AK, Getselter D, Gil S, Lowry CA, Vale W, Chen A.
A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proc Natl Acad Sci USA 107:19020-19025. [51]

Sztainberg Y and Chen A.
An environmental enrichment model for mice. Nat Protoc. 5:1535-1539. [44]

Kuperman Y, Issler O, Regev L, Musseri I, Navon I, Neufeld-Cohen A, Gil S, Chen A.
Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis. Proc Natl Acad Sci USA 107:8393-8398. [36]

Neufeld-Cohen A, Evans A, Getselter G, Spyroglou A, Hill A, Gil S, Beuschlein F, Lowry C, Vale W, Chen A.
Urocortin1 and 2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits. Mol. Psychiatry 15:426-441. [44]

Regev L, Ezrielev E, Gershon E, Gil S, Chen A.
Genetic approach for intracerebroventricular delivery. Proc Natl Acad Sci USA 107:4424-4429. [22]

Sztainberg Y, Kuperman Y, Tsoory M, Lebow M, Chen A.
The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1. Mol. Psychiatry 15:905-917. [89]