Available Positions

Postdoctoral position studying Long Noncoding RNA biology

Year(s)
Rotation: 
1st
2nd
3rd
Area: 
Life Sciences
Mathematics and Computer Science
Thursday, November 1, 2018

Our lab studies the biology of noncoding RNAs and their roles in gene regulation, with a particular focus on the recently emerging class of long intervening noncoding RNAs (lincRNAs). We use genomic and biochemical approaches alongside computational methods for studying functions and modes of actions of these RNAs, and also examine their evolution and work to place them in higher-order regulatory networks. To do so we use various combinations of novel and existing experimental and computational methods. Candidates with background in computational or molecular biology are sought, and those with a multidisciplinary background, spanning both life sciences and computer sciences, are especially encouraged to apply. Among candidates with background in molecular biology, preference will be given to those with experience in molecular work with RNA, biochemistry, genomics, and/or studying mammalian stem cells in culture.
The starting date is flexible. Interested and highly motivated applicants should send their CV and brief description of research interests to igor.ulitsky@weizmann.ac.il Informal inquiries are welcome.
Postdoctoral benefits are as described at http://www.fgs.org.il/en/

Experimental and computational approaches for studying the biology of long RNAs.

Year(s)
Rotation: 
Area: 
Life Sciences
Mathematics and Computer Science
Thursday, September 1, 2022

We are interested in understanding what kind of activities can long RNAs, including both long noncoding RNAs (lncRNAs) and mRNAs, or fragments thereof, carry out in mammalian cells. We particularly interested in the question of how these activities are encoded in the genomic sequences of these genes, how they are related to the secondary structures they adopt in cells, how mutations in lncRNA genes or in noncoding regions in mRNA UTRs affect their function, and how to exploit all this knowledge to design better therapeutic approaches for both rare and common diseases. We are addressing these questions using a combination of both experimental biology (including molecular biology, cell biology, stem cell biology, and neurobiology) and computational biology/bioinformatics. Postdoctoral positions focused on specific projects related to these questions are available.