Our research

Immunology research is transforming science and human health. Our immune system is critically important in protecting our body from bacterial, viral, fungal, and parasitic infection, while ensuring that we continuously nurture our commensal microbial partners, constituting the microbiome.

Dysregulation of immunity, in the form of immunodeficiency or immune over-activation can lead to life-threatening sepsis or the emergence of devastating autoimmune disease. In the past decade, immune system function was discovered to also impact “non-immune” diseases such as cancer, obesity, and even neuro-degenerative disease. Innovative immune interventions constitute the forefront of medical treatment, with examples spanning vaccination in COVID, immunomodulatory treatment in Inflammatory Bowel Disease (IBD), and cancer immunotherapy transforming the treatment of a variety of malignancies.  

The Department of Systems immunology has formed a first-of-its-kind home to inter-disciplinary research integrating immunology with diverse disciplines that span genomics, proteomics, computational biology, metabolism, neurology, microbiology, cancer research and medicine. We strive to develop a vibrant and inclusive community of researchers of diverse backgrounds that will advance science, medicine, and biotechnology for the benefit of humans and their environment. 

 

News

New article published in Cell by the Dahan and Amit labs

Bispecific dendritic-T Cell Engager potentiates anti-tumor immunity.

New Article published in Cell by The Amit Lab

Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma.