Functional genomics and transcriptomics in mouse models and humans

Genomic & state-dependent regulation of neural circuit plasticity

How diverse posttranscriptional modifications regulate the fate of mRNA

Studying cell-cell communication mechanisms of malaria parasites within a population and with their hosts

Our studies proceed along three major lines: (1) Microbial population dynamics under stress, (2) Understanding drought resistance and engineering drought-resistant nutritious plants (3) The plant microbiome and its dynamics

Shoot apical meristem, floral transition

An integrative approach for the exploration of melanoma genetic and immunological interactions

Chromosome Catastrophes in Cancer

We study the functional roles of epigenetics during cell-fate decisions

Our lab is a major driver in developing and applying cutting edge single-cell genomics technologies and advanced computational approaches. We apply these novel tools in animal models and human patients to uncover immune regulatory mechanisms and pathways

Combine molecular biology, biochemical and advanced microscopy techniques to study myelinating glial cells

Mechanisms of oligodendrocyte and white matter aging and rejuvenation.

Human evolution and disease

Proprioception and the the musculoskeletal system in development and disease

We study morphogenesis, cell biology and function of hypothalamic neurons, which regulate appetite, stress and social behavior

Functional genomics and systematic screens to uncover new protein functions

We study the structure, function and evolution of systems that regulate gene expression, with emphasis on translation

Our group brings the tools of systems biology to bear on the grand challenges of sustainability