Questions? Contact the Feinberg Graduate School at firstname.lastname@example.org
Note: Due to the multidisciplinary nature of scientific research, you may be interested in scanning the entire list of
rotations offered by scientists in all the faculties: chemistry, life sciences, physics, and mathematics/computer
science. There are for example, scientists in life sciences who are interested in rotation students in chemistry, and
scientists in physics who might supervise students in the life sciences. However, before beginning a rotation in an
area that is outside your own field of study, you must obtain the approval of the Head of the Board of Studies.
Research positions available in our department include:
Dr. Itay Tirosh
Looking for postdocs with computational background to study tumor biology
Our lab combines computational and experimental approaches to discover sub-populations of human tumor cells, study their biological functions and the therapeutic implications. For more details please see the lab website.
Prof. Valery Krizhanovsky
The dynamics of senescent cells during ageing
Senescent cells (SnCs) are cells that become damaged and stop dividing, secreting factors called senescence associated secreted profile (SASP). In young organisms, formation of SnCs is necessary in order to prevent cancer and repair wounds, keeping the tissue intact while the immune system removes the SnCs . However SnCs accumulate exponentially with age, becoming so abundant in old organisms that they cause chronic inflammation and slow regeneration to such an extent that they contribute to disease and death. We want to understand the timing of the accumulation of senescent cells and how it is regulated. If you are interested in ageing research and highly motivated to contribute to extension of health-span you are welcome to apply.
Prof. Valery Krizhanovsky
We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing"
We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing" at Weizmann Institute. The project is a collaboration of laboratories of Uri Alon, Tali Kimchi and Valery Krizhanovsky. It will combine cutting edge methods in molecular and cellular biology, behavioral neuroscience and system biology in mouse models. An expertise in behavioral neuroscience, molecular biology and mouse models is a plus.
Prof. Sima Lev
Ferroptosis is a newly discovered cell death pathway driven by iron-dependent lipid peroxidation. We recently discovered new inducers of ferroptosis, and specific metabolic states that increase vulnerability to ferroptosis, and thus can be used for cancer therapy. We have multidisciplinary projects related to ferroptosis in TNBC, and we are currently looking for two talented and enthusiastic postdocs to join us.
Prof. Sima Lev
Combination therapies for TNBC
Triple negative breast cancer (TNBC) is a highly aggressive disease that affects young women and currently has no effective treatment. The goal of our studies is to identify new therapeutic strategies for this particular subtype of breast cancer.
Synthetic lethality is a powerful approach to selectively eliminate vulnerable cancer cells, and thus can be exploited for cancer therapy. Many studies including our own indicate that synthetic lethality screens could be a promising approach to identify novel drug targets for TNBC. A postdoctoral position is available to establish a genome-wide synthetic lethal screen to identify potent combination therapies for TNBC subtypes.
Prof. Sima Lev
BRD4 as a therapeutic target for TNBC
BRD4 (Bromodomain protein 4), a member of the BET (bromodomain and extra terminal domain) family, is an epigenetic reader that plays important roles in chromatin remodeling and transcriptional regulation. It is involved in cancer progression, metastasis and inflammatory diseases and is considered as promising therapeutic targets for different cancer subtypes, including TNBC. Targeting of BRD4 in TNBC and overcoming drug resistance are current questions that we address.
Other positions available at the Weizmann Institute:
>> Undergraduate Summer Programs
>> Postdoctoral Fellowships
>> Visiting Professorships
>> Visiting Scientists
In addition to the above, PhD and postdoctoral positions are available with Igor Ulitsky's group. The Ulitsky lab will start operations in September 2013 and will study the biology of noncoding RNAs and their roles in gene regulation, with a particular focus on the recently emerging class of long intervening noncoding RNAs (lincRNAs). We will study modes of actions and functions of these RNAs, as well as their evolution and their roles in higher-order regulatory networks. To do so, we will use novel and existing techniques in genomics, systems biology, biochemistry and computational sequence analysis.
Candidates with background in computational or molecular biology are sought, and those with a multidisciplinary background, spanning both life sciences and computer sciences, are especially encouraged to apply. Among candidates with background in molecular biology, preference will be given to those with experience in molecular work with RNA, biochemical purifications, and/or studying mammalian stem cells in culture.
The starting date is flexible. Interested and highly motivated applicants should send their CV and brief description of research interests to email@example.com. Informal inquiries are welcome.
For more details and relevant publications see: http://jura.wi.mit.edu/bartel/ulitsky.
Graduate student and postdoctoral benefits are as described at http://www.fgs.org.il/en/.