Stress Linked Psychopathologies

Schroeder M, Jakovcevski M, Polacheck T, Lebow M, Drori Y, Engel M, Ben-Dor S, Chen A.
A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype. Cell Metab. 25:1269-1281.

Dedic N, Chen A, Deussing JM.
The CRF family of neuropeptides and their receptors - mediators of the central stress response. Curr Mol Pharmacol. 11(1):4-31.

Ramot A, Jiang Z, Tian JB, Nahum T, Kuperman Y, Justice NJ, Chen A.
Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress. Nat Neurosci. 20:385-388.

Volk N, Pape JC, Engel M, Zannas AS, Cattane N, Cattaneo A, Binder EB, Chen A.
Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress. Cell Rep. 17:1882-1891.

Henckens MJAG, Deussing JM, Chen A.
Region-specific roles of the corticotropin-releasing factor-urocortin system in stress. Nat Rev Neurosci. 17:636-651.

Henckens MJAG, Printz Y, Shamgar U, Lebow M, Drori Y, Kuehne C, Kolarz A, Deussing JM, Justice NJ, Yizhar O, Chen A.
The posterior bed nucleus of the stria terminalis critically contributes to stress recovery. Mol. Psychiatry 22:1691–1700.

Shemesh Y, Forkosh O, Mahn M, Anpilov S, Sztainberg Y, Manashirov S, Shlapobersky T, Eliott E, Tabouy L, Ezra G, Adler ES, Ben-Efraim Y, Gil S, Kuperman Y, Haramati S, Dine J, Eder M, Deussing JM, Schneidman E, Yizhar O, Chen A.
Ucn3–CRFR2 in the medial amygdala regulates complex social dynamics. Nat Neurosci. 19:1489-1496.

Kuperman Y, Weiss M, Dine J, Staikin K, Golani O, Ramot A, Nahum T, Kühne C, Shemesh Y, Wurst W, Harmelin A, Deussing JM, Eder M and Chen A.
CRFR1 in AgRP neurons modulates sympathetic nervous system activity to adapt to cold stress and fasting. Cell Metab. 23:1185-1199.

Lebow M and Chen A.
Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders. Mol. Psychiatry 21:450-463.

Elliott E, Manashirov S, Zwang R, Gil S, Tsoory M, Shemesh Y, Chen A.
Dnmt3a in the medial prefrontal cortex regulates anxiety-like behavior in adult mice. J Neurosci. 36:730-740.