Research

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Protein interactions by NMR

  • The interaction of HIV-1 envelope glycoprotein with the HIV-1 co-receptor CCR5
  • The interaction of chemokines with CCR5
  • The use of transferred NOE to study intermolecular interactions in large protein complexes
  • Vladimir Kost

    PI: Prof. Jacob Anglister

    Phone: +972-8-934-3531

    vladimir.kost@weizmann.ac.il

    Location: Helen and Milton A. Kimmelman Building, 550

  • Dr. Adi Moseri

    PI: Prof. Jacob Anglister

    adi.moseri@weizmann.ac.il

    Location: Helen and Milton A. Kimmelman Building, 506

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Cooperativity in protein structure, folding and function

  • Allostery in chaperonins
  • Mechanisms of action of chaperonins
  • Development of methods to study allostery
  • Correlated mutation analysis
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Structural biology – structure-function studies of transcription factors and of enzymes from pathogenic bacteria

  • The tumor-suppressor protein p53 and its interaction with DNA
  • Cancer-related p53 mutants and their rescue by suppressor mutations and by small molecules
  • Fatty-acid synthesis enzymes from Mycobacterium tuberculosis as potential drug targets
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  • Dr. Joshua Milgram

    PI: Prof. Stephen Weiner

    joshua.milgram@weizmann.ac.il

    Location: Helen and Milton A. Kimmelman Building

  • Noy Shaked

    PI: Prof. Stephen Weiner, Prof. Lia Addadi

    Phone: +972-8-934-3514

    noy.shaked@weizmann.ac.il

    Location: Helen and Milton A. Kimmelman Building, 568

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