You are here
Positions
Scientist | Description |
---|---|
Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>The relationship between hypoxia and the core circadian clock</p>
 |
Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>Biochemical identification of metabolic sensors</p>
 |
Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>The interplay between circadian clocks and exercise performance</p>
 |
Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>Computational analyses of rhythmic outputs (e.g. metabolites, gases)</p>
 |
Prof. Rivka Dikstein | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-2117 |
<p>Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to enviromental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for potential treatment of cancer, chronic inflammation and neurodegenrative diseases.</p>
 |
Dr. Nir Fluman | Rotation: 3rd Phone:+972-8-934-6456 |
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. |
Prof. Neta Regev-Rudzki | Rotation: 1st,2nd,3rd Phone:+972-8-934-3160 |
<p><strong>Our research combines molecular biology, microbiology, genetics (including CRISPR/Cas9), biochemistry, advanced imaging platforms, omics and biophysics.</strong></p>
 |
Prof. Ziv Reich | Rotation: 1st,2nd,3rd Phone:+972-8-934-2982 |
<p>Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model. </p>
 |
Prof. Gideon Schreiber | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-3249 |
<p>Our research group is interested in investigating all aspects of protein-protein interactions, from their biophysical nature to their role in signaling within the cell. As our cellular model system we are investigating the multiple activities of type I interferons. </p>
 |
Prof. Michal Sharon | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-3947 |
<p>Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.</p>
 |
Prof. Michael Walker | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-3597 |
<p>In our research, we focus on the following aspects of beta cell function:</p>
 |
Prof. David Wallach | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-3941 |
<p>Caspase-8, a cysteine protease discovered in our laboratory, is the main proximal signaling enzyme in the activation of the extrinsic cell-death pathway by receptors of the TNF/NGF family. In certain cells it also participates in the regulation of cell growth, differentiation and survival. A number of different human tumors, including small cell lung carcinoma, neuroblastoma, hepatocellular carcinoma, and others, are frequently deficient of caspase-8. |
Prof. David Wallach | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-3941 |
<p>Transgenic and conditional-knockout mouse models are applied to gain better knowledge of the physiological and pathophysiological function of the following signaling proteins that were discovered in our laboratory: (a) Caspase-8, a cysteine protease that we have initially found to serve as the main proximal signaling protein in the initiation of death induction by the receptors (the extrinsic cell-death pathway), yet has more recently found also to serve various non-apoptotic roles. |