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Positions

Positions | Msc Students
Scientist Description

Prof. Rivka Dikstein | 2 Years

Phone:+972-8-934-2117

rivka.dikstein@weizmann.ac.il

Homepage

<p>Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to environmental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation and neurodegenerative diseases.</p>&#xD;

Dr. Nir Fluman | 18 Months

Phone:+972-8-934-6456

nir.fluman@weizmann.ac.il

Homepage

Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools.

Prof. Ziv Reich | 2 Years

Phone:+972-8-934-2982

ziv.reich@weizmann.ac.il

Homepage

<p>The project employs CRISPR/Cas9 , advanced microscopy,&nbsp; microfluidics, various state-of-the-art single-cell and sequencing techniques&nbsp;</p>&#xD;

Prof. Eitan Reuveny | 2 Years

Phone:+972-8-934-3243

e.reuveny@weizmann.ac.il

Homepage

<p>G protein-coupled receptors (GPCRs) are the largest gene family in the human genome. Their role is to translate chemical information into cellular responses, like olfactory processing, neuronal activity modulation, and hormone actions or regulating blood pressure among many. Their cellular effectors can range from various enzymes to ion channels. Interestingly, nature has designed the GPCR as a major target for many natural compounds and the pharmaceutical industry has focused its attention on designing various agonists and antagonists to treat various illnesses.