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Positions
| Scientist | Description |
|---|---|
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| 2 Years Phone:+972-8-934- |
<p>How does a neuron grow? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. |
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Dr. Nir Fluman | 18 Months Phone:+972-8-934-6456 |
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. |
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Prof. Neta Regev-Rudzki | 1 Year Phone:+972-8-934-3160 |
<p>Join us to study the FASCINATING world of the malaria parasites!</p>
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| Scientist | Description |
|---|---|
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Prof. Gad Asher | 4 Years Phone:+972-8-934-6949 |
<p>Our lab has a longstanding interest in circadian clock resetting. We previously have identified and characterized novel resetting cues such as hypoxia and CO2. Recently, we have developed a new method to study resetting agents in vitro in an efficient and high-throughput manner, dubbed <a href="https://www.nature.com/articles/s41467-021-26210-1">Circa-SCOPE</a>. The method allows screening of multiple drugs in parallel to identify which affects the clock and how. |
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Prof. Gad Asher | 4 Years Phone:+972-8-934-6949 |
<p>Circadian clocks are key regulators of daily physiology and metabolism in mammals. Our understanding of the role of the circadian clock and specific clock proteins in controlling exercise capacity is rudimentary. Consequently, there is growing interest in exercise biology in general, specifically in its interaction with other processes that govern whole-body physiology and metabolism. |
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Prof. Gad Asher | 4 Years Phone:+972-8-934-6949 |
<p>We demonstrated that low-amplitude oxygen cycles, which mimic the daily physiological cycles in oxygen levels observed in rodents, can reset the clock in a HIF-1a-dependent manner (<a href="https://www.weizmann.ac.il/Biomolecular_Sciences/Asher/publications" style="color: rgb(30, 121, 159); text-transform: none; text-indent: 0px; letter-spacing: normal; font-family: "Proxima Nova"; font-size: 15px; font-style: normal; font-weight: 400; word-spacing: 0px; white-space: normal; orphans: 2; widows: 2; font-variant-ligatures: normal; font-variant-caps: n |
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Prof. Rivka Dikstein | 5 Years Phone:+972-8-934-2117 |
<p>Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to environmental stimuli, (ii) to reveal the connections between the transcription and translation processes, and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation, and neurodegenerative diseases.</p>
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| 5 Years Phone:+972-8-934- |
<p>How does a neuron grow? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. |
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Dr. Nir Fluman | 4.5 Years Phone:+972-8-934-6456 |
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. |
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Prof. Neta Regev-Rudzki | 5 Years Phone:+972-8-934-3160 |
<p><strong>Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. |
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Prof. Eitan Reuveny | 5 Years Phone:+972-8-934-3243 |
<p>We have open positions for Ph.D. candidates interested in mechanisms of channel regulation by GPCRs using, but not limited to, computational (molecular dynamics), electrophysiological, molecular and/or optical methodologies.</p>
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Prof. Eitan Reuveny | 48 Months Phone:+972-8-934-3243 |
<p><strong>We have open positions for Ph.D. candidates or Postdoc candidates interested in mechanisms of channels function, GPCRs regulation of Cellular processes emphasizing on ion channel regulation and the interaction between animal toxins and ion channels.</strong></p>
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| Scientist | Description |
|---|---|
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Prof. Gad Asher | 2 Years Phone:+972-8-934-6949 |
<p>The relevant projects address the influence of circadian clocks on exercise performance, and training efficiency, as well as the effect of chronotype, feeding, and hypoxia on exercise capacity.</p>
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Prof. Gad Asher | 2 Years Phone:+972-8-934-6949 |
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Prof. Rivka Dikstein | 3 Years Phone:+972-8-934-2117 |
<p>Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to environmental stimuli, (ii) to reveal the connections between the transcription and translation processes, and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation, and neurodegenerative diseases.</p>
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| 5 Years Phone:+972-8-934- |
<p>How does a neuron grow? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. |
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Dr. Nir Fluman | 2 Years Phone:+972-8-934-6456 |
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. |
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Prof. Neta Regev-Rudzki | 3 Years Phone:+972-8-934-3160 |
<p>Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous. This is a full-time position available from October 2023 for a period of two years with a possibility of a further extension subject to funding availability. Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki. |
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Prof. Neta Regev-Rudzki | 3 Years Phone:+972-8-934-3160 |
<p>Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms or advanced protein chemistry is advantageous. This is a full-time position available for a period of three years with a possibility of a further extension subject to funding availability. Candidate should send a cover letter and CV (includes a publication list) to Prof. Neta Regev-Rudzki. |
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Prof. Eitan Reuveny | 48 Months Phone:+972-8-934-3243 |
<p><strong>We have open positions for Ph.D. candidates or Postdoc candidates interested in mechanisms of channels function, GPCRs regulation of Cellular processes emphasizing on ion channel regulation and the interaction between animal toxins and ion channels.</strong></p>
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| Scientist | Description |
|---|---|
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Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>Biochemical identification of metabolic sensors</p>
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Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>Computational analyses of rhythmic outputs (e.g. metabolites, gases)</p>
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Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>The relationship between hypoxia and the core circadian clock</p>
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Prof. Gad Asher | Rotation: 1st, 2nd, 3rd Phone:+972-8-934-6949 |
<p>The interplay between circadian clocks and exercise performance</p>
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Prof. Rivka Dikstein | Rotation: 2nd,3rd Phone:+972-8-934-2117 |
<p>Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli in health and disease</p>
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| Rotation: 1st, 2nd, 3rd Phone:+972-8-934- |
<p>How does a neuron grow? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. |
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Dr. Nir Fluman | Rotation: 3rd Phone:+972-8-934-6456 |
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. |
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Prof. Neta Regev-Rudzki | Rotation: 1st,2nd,3rd Phone:+972-8-934-3160 |
<p><strong>Our research combines molecular biology, microbiology, genetics (including CRISPR/Cas9), biochemistry, advanced imaging platforms, omics and biophysics.</strong></p>
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Prof. Neta Regev-Rudzki | Rotation: 1st,2nd,3rd Phone:+972-8-934-3160 |
<p>We are seeking for highly motivated, committed and curious students to join our team as rotation students. The projects center on different fascinating aspects of the cellular biology of the malaria parasite.</p>
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Prof. Gideon Schreiber | Rotation: 1st,2nd,3rd Phone:+972-8-934-3249 |
<p>We aim to understand how different signaling outcomes are driven by the same input from a specific cytokine. In addition, we are interested to understand the synergic activities of different cytokines using the same intracellular effectors for signaling. </p>
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We do not currently have open positions