- Bochner F, Fellus-Alyagor L, Ketter D, Golani O, Biton I, Neeman M.
Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours.
Br J Cancer. 2020 May 11. PMID: 32390007 - Cohen B, Tempelhof H, Raz T, Oren R, Nicenboim J, Bochner F, Even R, Jelinski A, Eilam R, Ben-Dor S, Adaddi Y, Golani O, Lazar S, Yaniv K, Neeman M.
BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression.
Life Sci Alliance. 2020 Mar 4;3(4):e202000666. PMID: 32132179 - Lerner S, Anderzhanova E, Verbitsky S, Eilam R, Kuperman Y, Tsoory M, Kuznetsov Y, Brandis A, Mehlman T, Mazkereth R; UCDC Neuropsychologists, McCarter R, Segal M, Nagamani SCS, Chen A, Erez A.
ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus.
Cell Rep. 2019 Nov 19;29(8):2144-2153.e7. PMID: 31747589 - Aharoni R, Schottlender N, Bar-Lev DD, Eilam R, Sela M, Tsoory M, Arnon R.
Cognitive impairment in an animal model of multiple sclerosis and its amelioration by glatiramer acetate.
Sci Rep. 2019 Mar 11;9(1):4140. PMID: 30858445 - Silberman A, Goldman O, Boukobza Assayag O, Jacob A, Rabinovich S, Adler L, Lee JS, Keshet R, Sarver A, Frug J, Stettner N, Galai S, Persi E, Halpern KB, Zaltsman-Amir Y, Pode-Shakked B, Eilam R, Anikster Y, Nagamani SCS, Ulitsky I, Ruppin E, Erez A.
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer.
Cancer Res. 2019 Feb 1;79(3):518-533. PMID: 30573518 - Moor AE, Harnik Y, Ben-Moshe S, Massasa EE, Rozenberg M, Eilam R, Bahar Halpern K, Itzkovitz S.
Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis.
Cell. 2018 Nov 1;175(4):1156-1167.e15. PMID: 30270040 - Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, Keshet R, Stettner N, Silberman A, Agemy L, Helbling D, Eilam R, Sun Q, Brandis A, Malitsky S, Itkin M, Weiss H, Pinto S, Kalaora S, Levy R, Barnea E, Admon A, Dimmock D, Stern-Ginossar N, Scherz A, Nagamani SCS, Unda M, Wilson DM 3rd, Elhasid R, Carracedo A, Samuels Y, Hannenhalli S, Ruppin E, Erez A.
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.
Cell. 2018 Sep 6;174(6):1559-1570.e22. PMID: 30100185 - Stettner N, Rosen C, Bernshtein B, Gur-Cohen S, Frug J, Silberman A, Sarver A, Carmel-Neiderman NN, Eilam R, Biton I, Pevsner-Fischer M, Zmora N, Brandis A, Bahar Halpern K, Mazkereth R, di Bernardo D, Brunetti-Pierri N, Premkumar MH, Dank G, Nagamani SCS, Jung S, Harmelin A, Erez A.
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer.
Cell Rep. 2018 May 15;23(7):1962-1976. PMID: 29768197 - Sagiv A, Bar-Shai A, Levi N, Hatzav M, Zada L, Ovadya Y, Roitman L, Manella G, Regev O, Majewska J, Vadai E, Eilam R, Feigelson SW, Tsoory M, Tauc M, Alon R, Krizhanovsky V.
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence.
Cell Rep. 2018 Mar 27;22(13):3468-3479. PMID: 29590616 - Eilam R, Segal M, Malach R, Sela M, Arnon R, Aharoni R.
Astrocyte disruption of neurovascular communication is linked to cortical damage in an animal model of multiple sclerosis.
Glia. 2018 May;66(5):1098-1117. PMID: 29424049 - Oren R, Fellus-Alyagor L, Addadi Y, Bochner F, Gutman H, Blumenreich S, Dafni H, Dekel N, Neeman M, Lazar S.
Whole Organ Blood and Lymphatic Vessels Imaging (WOBLI).
Sci Rep. 2018 Jan 23;8(1):1412. PMID: 29362484 - Walvoort MT, Testa C, Eilam R, Aharoni R, Nuti F, Rossi G, Real-Fernandez F, Lanzillo R, Brescia Morra V, Lolli F, Rovero P, Imperiali B, Papini AM.
Erratum: Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae.
Sci Rep. 2017 Mar 22;7:44969. PMID: 28327637 - Walvoort MT, Testa C, Eilam R, Aharoni R, Nuti F, Rossi G, Real-Fernandez F, Lanzillo R, Brescia Morra V, Lolli F, Rovero P, Imperiali B, Papini AM.
Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae.
Sci Rep. 2016 Dec 23;6:39430. PMID: 28008952 - Eilam R, Aharoni R, Arnon R, Malach R.
Astrocyte morphology is confined by cortical functional boundaries in mammals ranging from mice to human.
Elife. 2016 Jun 10;5. pii: e15915. PMID: 27282388 - Vardi A, Zigdon H, Meshcheriakova A, Klein AD, Yaacobi C, Eilam R, Kenwood BM, Rahim AA, Massaro G, Merrill AH Jr, Vitner EB, Futerman AH.
Delineating pathological pathways in a chemically induced mouse model of Gaucher disease.
J Pathol. 2016 Aug;239(4):496-509. PMID: 27234572 - Fellerhoff-Losch B, Korol SV, Ganor Y, Gu S, Cooper I, Eilam R, Besser M, Goldfinger M, Chowers Y, Wank R, Birnir B, Levite M.
Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway.
J Neural Transm (Vienna). 2016 Mar;123(3):137-57. PMID: 26611796 - Bochner F, Fellus-Alyagor L, Kalchenko V, Shinar S, Neeman M.
A Novel Intravital Imaging Window for Longitudinal Microscopy of the Mouse Ovary.
Sci Rep. 2015 Jul 24;5:12446. PMID: 26207832 - Emde A, Eitan C, Liou LL, Libby RT, Rivkin N, Magen I, Reichenstein I, Oppenheim H, Eilam R, Silvestroni A, Alajajian B, Ben-Dov IZ, Aebischer J, Savidor A, Levin Y, Sons R, Hammond SM, Ravits JM, Möller T, Hornstein E.
Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.
EMBO J. 2015 Nov 3;34(21):2633-51. PMID: 26330466 - Cohen-Dvashi H, Ben-Chetrit N, Russell R, Carvalho S, Lauriola M, Nisani S, Mancini M, Nataraj N, Kedmi M, Roth L, Köstler W, Zeisel A, Yitzhaky A, Zylberg J, Tarcic G, Eilam R, Wigelman Y, Will R, Lavi S, Porat Z, Wiemann S, Ricardo S, Schmitt F, Caldas C, Yarden Y.
Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.
EMBO Mol Med. 2015 Mar;7(3):299-314. PMID: 25678558 - Harari D, Kuhn N, Abramovich R, Sasson K, Zozulya AL, Smith P, Schlapschy M, Aharoni R, Köster M, Eilam R, Skerra A, Schreiber G.
Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis.
J Biol Chem. 2014 Oct 17;289(42):29014-29. PMID: 25193661 - From R, Eilam R, Bar-Lev DD, Levin-Zaidman S, Tsoory M, LoPresti P, Sela M, Arnon R, Aharoni R.
Oligodendrogenesis and myelinogenesis during postnatal development effect of glatiramer acetate.
Glia. 2014 Apr;62(4):649-65. PMID: 24481644 - Vandoorne K, Vandsburger MH, Raz T, Shalev M, Weisinger K, Biton I, Brumfeld V, Raanan C, Nevo N, Eilam R, Hemmings BA, Tzahor E, Harmelin A, Gepstein L, Neeman M.
Chronic Akt1 deficiency attenuates adverse remodeling and enhances angiogenesis after myocardial infarction.
Circ Cardiovasc Imaging. 2013 Nov;6(6):992-1000. PMID: 24134954 - Aharoni R, Aricha R, Eilam R, From I, Mizrahi K, Arnon R, Souroujon MC, Fuchs S.
Age dependent course of EAE in Aire-/- mice.
J Neuroimmunol. 2013 Sep 15;262(1-2):27-34. PMID: 23849800 - Vandsburger MH, Radoul M, Addadi Y, Mpofu S, Cohen B, Eilam R, Neeman M.
Ovarian carcinoma: quantitative biexponential MR imaging relaxometry reveals the dynamic recruitment of ferritin-expressing fibroblasts to the angiogenic rim of tumors.
Radiology. 2013 Sep;268(3):790-801. PMID: 23801774 - Aharoni R, Sasson E, Blumenfeld-Katzir T, Eilam R, Sela M, Assaf Y, Arnon R.
Magnetic resonance imaging characterization of different experimental autoimmune encephalomyelitis models and the therapeutic effect of glatiramer acetate.
Exp Neurol. 2013 Feb;240:130-44. PMID: 23153580 - Aharoni R, Saada R, Eilam R, Hayardeny L, Sela M, Arnon R.
Oral treatment with laquinimod augments regulatory T-cells and brain-derived neurotrophic factor expression and reduces injury in the CNS of mice with experimental autoimmune encephalomyelitis.
J Neuroimmunol. 2012 Oct 15;251(1-2):14-24. PMID: 22749337 - Vitner EB, Farfel-Becker T, Eilam R, Biton I, Futerman AH.
Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.
Brain. 2012 Jun;135(Pt 6):1724-35. PMID: 22566609 - Levanon D, Bernstein Y, Negreanu V, Bone KR, Pozner A, Eilam R, Lotem J, Brenner O, Groner Y.
Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function.
EMBO Mol Med. 2011 Oct;3(10):593-604. PMID: 21786422 - Aharoni R, Vainshtein A, Stock A, Eilam R, From R, Shinder V, Arnon R.
Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate.
J Autoimmun. 2011 Nov;37(3):228-41. PMID: 21752599 - Kozela E, Lev N, Kaushansky N, Eilam R, Rimmerman N, Levy R, Ben-Nun A, Juknat A, Vogel Z.
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.
Br J Pharmacol. 2011 Aug;163(7):1507-19. PMID: 21449980 - Yablecovitch D, Shabat-Simon M, Aharoni R, Eilam R, Brenner O, Arnon R.
Beneficial effect of glatiramer acetate treatment on syndecan-1 expression in dextran sodium sulfate colitis.
J Pharmacol Exp Ther. 2011 May;337(2):391-9. PMID: 21310817 - Farfel-Becker T, Vitner EB, Pressey SN, Eilam R, Cooper JD, Futerman AH.
Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease.
Hum Mol Genet. 2011 Apr 1;20(7):1375-86. PMID: 21252206 - Vitner EB, Dekel H, Zigdon H, Shachar T, Farfel-Becker T, Eilam R, Karlsson S, Futerman AH.
Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses.
Hum Mol Genet. 2010 Sep 15;19(18):3583-90. PMID: 20616152 - Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N, McGlinn E, Heiser PW, Wills AM, Wirguin I, Rubin LL, Misawa H, Tabin CJ, Brown R Jr, Chen A, Hornstein E.
miRNA malfunction causes spinal motor neuron disease.
Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13111-6. PMID: 20616011 - Aharoni R, Eilam R, Stock A, Vainshtein A, Shezen E, Gal H, Friedman N, Arnon R.
Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE.
J Neuroimmunol. 2010 Aug 25;225(1-2):100-11. PMID: 20554028 - Yavin E, Himovichi E, Eilam R.
Delayed cell migration in the developing rat brain following maternal omega 3 alpha linolenic acid dietary deficiency.
Neuroscience. 2009 Sep 15;162(4):1011-22. PMID: 19447164 - Dadiani M, Seger D, Kreizman T, Badikhi D, Margalit R, Eilam R, Degani H.
Estrogen regulation of vascular endothelial growth factor in breast cancer in vitro and in vivo: the role of estrogen receptor alpha and c-Myc.
Endocr Relat Cancer. 2009 Sep;16(3):819-34. PMID: 19398483 - Aharoni R, Herschkovitz A, Eilam R, Blumberg-Hazan M, Sela M, Bruck W, Arnon R.
Demyelination arrest and remyelination induced by glatiramer acetate treatment of experimental autoimmune encephalomyelitis.
Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11358-63. PMID: 18678887 - Frumkin D, Wasserstrom A, Itzkovitz S, Stern T, Harmelin A, Eilam R, Rechavi G, Shapiro E.
Cell lineage analysis of a mouse tumor.
Cancer Res. 2008 Jul 15;68(14):5924-31. PMID: 18632647 - Kuperstein F, Eilam R, Yavin E.
Altered expression of key dopaminergic regulatory proteins in the postnatal brain following perinatal n-3 fatty acid dietary deficiency.
J Neurochem. 2008 Jul;106(2):662-71. PMID: 18410511 - Aharoni R, Sonego H, Brenner O, Eilam R, Arnon R.
The therapeutic effect of glatiramer acetate in a murine model of inflammatory bowel disease is mediated by anti-inflammatory T-cells.
Immunol Lett. 2007 Oct 15;112(2):110-9. PMID: 17719654 - Hassid Y, Furman-Haran E, Margalit R, Eilam R, Degani H.
Noninvasive magnetic resonance imaging of transport and interstitial fluid pressure in ectopic human lung tumors.
Cancer Res. 2006 Apr 15;66(8):4159-66. PMID: 16618737 - Butovsky E, Juknat A, Elbaz J, Shabat-Simon M, Eilam R, Zangen A, Altstein M, Vogel Z.
Chronic exposure to Delta9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas.
Mol Cell Neurosci. 2006 Apr;31(4):795-804. PMID: 16513365 - Rosen Y, Ramniceanu G, Margalit R, Grobgeld D, Eilam R, Degani H, Furman-Haran E.
Vascular perfusion of human lung cancer in a rat orthotopic model using dynamic contrast-enhanced magnetic resonance imaging.
Int J Cancer. 2006 Jul 15;119(2):365-72. PMID: 16470842 - Aharoni R, Eilam R, Domev H, Labunskay G, Sela M, Arnon R.
The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice.
Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19045-50. PMID: 16365293 - Stettner N, Brenner O, Eilam R, Harmelin A.
Pegylated liposomal doxorubicin as a chemotherapeutic agent for treatment of canine transmissible venereal tumor in murine models.
J Vet Med Sci. 2005 Nov;67(11):1133-9. PMID: 16327225 - Aharoni R, Arnon R, Eilam R.
Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis.
J Neurosci. 2005 Sep 7;25(36):8217-28. PMID: 16148229 - Ganor Y, Gottlieb M, Eilam R, Otmy H, Teichberg VI, Levite M.
Immunization with the glutamate receptor-derived peptide GluR3B induces neuronal death and reactive gliosis, but confers partial protection from pentylenetetrazole-induced seizures.
Exp Neurol. 2005 Sep;195(1):92-102. PMID: 15907325 - Butovsky E, Juknat A, Goncharov I, Elbaz J, Eilam R, Zangen A, Vogel Z.
In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol.
J Neurochem. 2005 May;93(4):802-11. PMID: 15857384 - Eliash S, Shteter N, Eilam R.
Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model.
J Neural Transm (Vienna). 2005 Aug;112(8):991-1003. PMID: 15765264 - Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y.
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.
J Biol Chem. 2005 Mar 4;280(9):8503-12. PMID: 15611079 - Erez N, Milyavsky M, Eilam R, Shats I, Goldfinger N, Rotter V.
Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
Cancer Res. 2003 Dec 15;63(24):8777-83. PMID: 14695194 - Aharoni R, Kayhan B, Eilam R, Sela M, Arnon R.
Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ.
Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14157-62. PMID: 14614135 - Dafni H, Gilead A, Nevo N, Eilam R, Harmelin A, Neeman M.
Modulation of the pharmacokinetics of macromolecular contrast material by avidin chase: MRI, optical, and inductively coupled plasma mass spectrometry tracking of triply labeled albumin.
Magn Reson Med. 2003 Nov;50(5):904-14. PMID: 14587000 - Eilam R, Peter Y, Groner Y, Segal M.
Late degeneration of nigro-striatal neurons in ATM-/- mice.
Neuroscience. 2003;121(1):83-98. PMID: 12946702 - Levanon D, Glusman G, Bettoun D, Ben-Asher E, Negreanu V, Bernstein Y, Harris-Cerruti C, Brenner O, Eilam R, Lotem J, Fainaru O, Goldenberg D, Pozner A, Woolf E, Xiao C, Yarmus M, Groner Y.
Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3.
Blood Cells Mol Dis. 2003 Mar-Apr;30(2):161-3. PMID: 12732178 - Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, Eilam R, Bernstein Y, Goldenberg D, Xiao C, Fliegauf M, Kremer E, Otto F, Brenner O, Lev-Tov A, Groner Y.
The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons.
EMBO J. 2002 Jul 1;21(13):3454-63. PMID: 12093746 - Levanon D, Brenner O, Negreanu V, Bettoun D, Woolf E, Eilam R, Lotem J, Gat U, Otto F, Speck N, Groner Y.
Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis.
Mech Dev. 2001 Dec;109(2):413-7. PMID: 11731260 - Golomb E, Rosenzweig N, Eilam R, Abramovici A.
Spontaneous hyperplasia of the ventral lobe of the prostate in aging genetically hypertensive rats.
J Androl. 2000 Jan-Feb;21(1):58-64. PMID: 10670520 - Eilam R, Davidson A, Gozes I, Segal M.
Locomotor activity causes a rapid up-regulation of vasoactive intestinal peptide in the rat hippocampus.
Hippocampus. 1999;9(5):534-41. PMID: 10560924 - Eilam R, Peter Y, Elson A, Rotman G, Shiloh Y, Groner Y, Segal M.
Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice.
Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12653-6. PMID: 9770541 - Eilam R, Pinkas-Kramarski R, Ratzkin BJ, Segal M, Yarden Y.
Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain.
Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1888-93. PMID: 9465112 - Pinkas-Kramarski R, Eilam R, Alroy I, Levkowitz G, Lonai P, Yarden Y.
Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation.
Oncogene. 1997 Dec 4;15(23):2803-15. PMID: 9419971 - Pinkas-Kramarski R, Eilam R, Spiegler O, Lavi S, Liu N, Chang D, Wen D, Schwartz M, Yarden Y.
Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes.
Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9387-91. PMID: 7937775 - Eilam R, Malach R, Segal M.
Selective elimination of hypothalamic neurons by grafted hypertension-inducing neural tissue.
J Neurosci. 1994 Aug;14(8):4891-902. PMID: 7913956 - Bendel P, Eilam R.
Quantitation of ventricular size in normal and spontaneously hypertensive rats by magnetic resonance imaging.
Brain Res. 1992 Mar 6;574(1-2):224-8. PMID: 1638395 - Eilam R, Malach R, Bergmann F, Segal M.
Hypertension induced by hypothalamic transplantation from genetically hypertensive to normotensive rats.
J Neurosci. 1991 Feb;11(2):401-11. PMID: 1992008 - Avidor R, Eilam R, Malach R, Gozes I.
VIP-mRNA is increased in hypertensive rats.
Brain Res. 1989 Dec 4;503(2):304-7. PMID: 2605522