Efficacy of an AAV vector encoding a thermostable form of glucocerebrosidase in alleviating symptoms in a Gaucher disease mouse model , Milenkovic I., Blumenreich S., Hochfelder A., Azulay A., Biton I. E., Zerbib M., Oren R., Tsoory M., Joseph T., Fleishman S. J. & Futerman A. H., 9-10, Gene Therapy, 439-444, 31, 2024, https://doi.org/10.1038/s41434-024-00476-8
Store-operated Ca2+ entry regulatory factor alters murine metabolic state in an age-dependent manner via hypothalamic pathways , Gataulin D., Kuperman Y., Tsoory M., Biton I. E., Nataniel T., Palty R., Karbat I., Meshcheriakova A. & Reuveny E., 3, PNAS Nexus, , 2, 2023, https://doi.org/10.1093/pnasnexus/pgad068
Cooperative Doping in Ultrasmall BaF<sub>2</sub> Nanocrystals for Multimodal <sup>19</sup>F-MRI and CT Applications , Cohen D., Houben L., Galisova A., Feldman Y., Fox S., Biton I. E. & Bar-Shir A., 14, ACS Applied Nano Materials, 13107-13115, 6, 2023, https://doi.org/10.1021/acsanm.3c01809
Prediction of Ovarian Follicular Dominance by MRI Phenotyping of Hormonally Induced Vascular Remodeling , Fellus-Alyagor L., Biton I. E., Dafni H., Bochner F., Rotkopf R., Dekel N. & Neeman M., , Frontiers in Medicine, , 8, 2021, https://doi.org/10.3389/fmed.2021.711810
A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation , Tamim-Yecheskel B., Fraiberg M., Kokabi K., Freud S., Shatz O., Marvaldi L., Subic N., Brenner O., Tsoory M., Eilam-Altstadter R., Biton I., Savidor A., Dezorella N., Heimer G., Behrends C., Ben-Zeev B. & Elazar Z., 10, Autophagy, 3082-3095, 17, 2021, https://doi.org/10.1080/15548627.2020.1852724
Brain pathology and cerebellar purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease , Pewzner-Jung Y., Joseph T., Blumenreich S., Vardi A., Ferreira N. S., Cho S. M., Eilam R., Tsoory M., Biton I. E., Brumfeld V., Haffner-Krausz R., Brenner O., Sharabi N., Addadi Y., Salame T. M., Rotkopf R., Wigoda N., Yayon N., Merrill A. H., Schiffmann R. & Futerman A. H., , Progress in Neurobiology, , 197, 2021, https://doi.org/10.1016/j.pneurobio.2020.101939
Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours , Bochner F., Fellus-Alyagor L., Ketter D., Golani O., Biton I. & Neeman M., 2, British Journal of Cancer, 216-225, 123, 2020, https://doi.org/10.1038/s41416-020-0878-7
Piezo2 expressed in proprioceptive neurons is essential for skeletal integrity , Assaraf E., Blecher R., Heinemann-Yerushalmi L., Krief S., Carmel Vinestock R., Biton I. E., Brumfeld V., Rotkopf R., Avisar E., Agar G. & Zelzer E., 1, Nature Communications, , 11, 2020, https://doi.org/10.1038/s41467-020-16971-6
Novel multimodal molecular imaging of Vitamin H (Biotin) transporter activity in the murine placenta , Ben Eliezer N., Lysenko M., Biton I. E., Golani O., Bartels J. L., Fernandez S. R., Aweda T. A., Clanton N. A., Beacham R., Lapi S. E., Garbow J. R. & Neeman M., 1, Scientific Reports, , 10, 2020, https://doi.org/10.1038/s41598-020-77704-9
Potential roles of gut microbiome and metabolites in modulating ALS in mice , Blacher E., Bashiardes S., Shapiro H., Rothschild D., Mor U., Dori-Bachash M., Kleimeyer C., Moresi C., Harnik Y., Zur M., Zabari M., Brik R. B., Kviatcovsky D., Zmora N., Cohen Y., Bar N., Levi I., Amar N., Mehlman T., Brandis A., Biton I., Kuperman Y., Tsoory M., Alfahel L., Harmelin A., Schwartz M., Israelson A., Arike L., Johansson M. E. V., Hansson G. C., Gotkine M., Segal E. & Elinav E., 7770, Nature, 474-480, 572, 2019, https://doi.org/10.1038/s41586-019-1443-5
Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability , Rom A., Melamed L., Gil N., Goldrich M. J., Kadir R., Golan M., Biton I., Perry R. B. & Ulitsky I., 1, Nature Communications, , 10, 2019, https://doi.org/10.1038/s41467-019-13075-8
Cerebellar Learning Properties Are Modulated by the CRF Receptor , Ezra-Nevo G., Prestori F., Locatelli F., Soda T., ten Brinke M. M., Engel M., Boele H., Botta L., Leshkowitz D., Ramot A., Tsoory M., Biton I. E., Deussing J., D'Angelo E., De Zeeuw C. I. & Chen A., 30, Journal of Neuroscience, 6751-6765, 38, 2018, https://doi.org/10.1523/JNEUROSCI.3106-15.2018
Assessing Mucosal Inflammation in a DSS-Induced Colitis Mouse Model by MR Colonography , Biton I. E., Stettner N., Brener O., Erez A., Harmelin A. & Garbow J. R., 1, Tomography, 4-13, 4, 2018, https://doi.org/10.18383/j.tom.2017.00021
Microglial MHC class II is dispensable for experimental autoimmune encephalomyelitis and cuprizone-induced demyelination , Wolf Y., Shemer A., Levy-Efrati L., Gross M., Kim J., Engel A., David E., Chappell-Maor L., Grozovski J., Rotkopf R., Biton I., Eilam-Altstadter R. & Jung S., 8, European Journal of Immunology, 1308-1318, 48, 2018, https://doi.org/10.1002/eji.201847540
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer , Stettner N., Rosen C., Bernshtein B., Gur-Cohen S., Frug J., Silberman A., Sarver A., Carmel-Neiderman N. N., Eilam R., Biton I., Pevsner-Fischer M., Zmora N., Brandis A., Halpern K. B., Mazkereth R., di Bernardo D., Brunetti-Pierri N., Premkumar M. H., Dank G., Nagamani S. C. S., Jung S., Harmelin A. & Erez A., 7, Cell Reports, 1962-1976, 23, 2018, https://doi.org/10.1016/j.celrep.2018.04.053
The Proprioceptive System Masterminds Spinal Alignment: Insight into the Mechanism of Scoliosis , Blecher R., Krief S., Galili T., Biton I. E., Stern T., Assaraf E., Levanon D., Appel E., Anekstein Y., Agar G., Groner Y. & Zelzer E., 4, Developmental Cell, 388-399.e3, 42, 2017, https://doi.org/10.1016/j.devcel.2017.07.022
A macrocyclic <sup>19</sup>F-MR based probe for Mn<sup>2 +</sup> sensing , Sarkar A., Biton I. E., Neeman M. & Datta A., , Inorganic Chemistry Communications, 21-24, 78, 2017, https://doi.org/10.1016/j.inoche.2017.02.008
In Vivo Preclinical Imaging of Developmental Biology , Vandoorne K., Raz T., Sapoznik S., Biton I. E., Garbow J. R. & Neeman M., , , 627-650, , 2017, https://doi.org/10.1007/978-3-319-42202-2_25
MR Imaging-derived Oxygen- Hemoglobin dissociation curves and Fetal-Placental Oxygen- Hemoglobin affinities , Avni R., Golani O., Akselrod-Ballin A., Cohen Y., Biton I., Garbow J. R. & Neeman M., 1, Radiology, 68-77, 280, 2016, https://doi.org/10.1148/radiol.2015150721
Multimodal Correlative Preclinical Whole Body Imaging and Segmentation , Akselrod-Ballin A., Dafni H., Addadi Y., Biton I., Avni R., Brenner Y. & Neeman M., , Scientific Reports, , 6, 2016, https://doi.org/10.1038/srep27940
Persistent microbiome alterations modulate the rate of post-dieting weight regain , Thaiss C. A., Itav S., Rothschild D., Meijer M. T., Levy M., Moresi C., Dohnalová L., Braverman S., Rozin S., Malitsky S., Dori-Bachash M., Kuperman Y., Biton I., Gertler A., Harmelin A., Shapiro H., Halpern Z., Aharoni A., Segal E. & Elinav E., 7634, Nature, 544-551, 540, 2016, https://doi.org/10.1038/nature20796
The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation , Aylon Y., Gershoni A., Rotkopf R., Biton I. E., Porat Z., Koh A. P., Sun X., Lee Y., Fiel M., Hoshida Y., Friedman S. L., Johnson R. L. & Oren M., 7, GENES & DEVELOPMENT, 786-797, 30, 2016, https://doi.org/10.1101/gad.274167.115
Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice , Rosen C., Shezen E., Aronovich A., Klionsky Y., Yaakov Y., Assayag M., Biton I., Shakhar G., Tal O., Ben-Hur H., Shneider D., Vaknin Z., Sadan O., Evron S., Freud E., Shoseyov D., Wilschanski M., Berkman N., Fibbe W., Hagin D., Hillel-Karniel C., Krentsis I., Bachar-Lustig E. & Reisner Y., 8, Nature Medicine, 869-879, 21, 2015, https://doi.org/10.1038/nm.3889
Mrs of brain metabolite levels demonstrates the ability of scavenging of excess brain glutamate to protect against nerve agent induced seizures , Ruban A., Biton I. E., Markovich A. & Mirelman D., 2, International Journal of Molecular Sciences, 3226-3236, 16, 2015, https://doi.org/10.3390/ijms16023226
Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis , Thaiss C. A., Zeevi D., Levy M., Zilberman-Schapira G., Suez J., Tengeler A. C., Abramson L., Katz M. N., Korem T., Zmora N., Kuperman Y., Biton I., Gilad S., Harmelin A., Shapiro H., Halpern Z., Segal E. & Elinav E., 3, Cell, 514-529, 159, 2014, https://doi.org/10.1016/j.cell.2014.09.048
In search of signaling pathways critical for ovarian graft reception: Akt1 is essential for long-term survival of ovarian grafts , Cohen Y., Dafni H., Avni R., Raz T., Biton I., Hemmings B. & Neeman M., 2, Fertility and Sterility, 536-544.e2, 101, 2014, https://doi.org/10.1016/j.fertnstert.2013.10.007
Rasagiline prevents neurodegeneration in thiamine deficient rats - A longitudinal MRI study , Dror V., Rehavi M., Biton I. E. & Eliash S., , Brain Research, 43-54, 1557, 2014, https://doi.org/10.1016/j.brainres.2013.12.030
Chronic Akt1 deficiency attenuates adverse remodeling and enhances angiogenesis after myocardial infarction , Vandoorne K., Vandsburger M. H., Raz T., Shalev M., Weisinger K., Biton I., Brumfeld V., Raanan C., Nevo N., Eilam R., Hemmings B. A., Tzahor E., Harmelin A., Gepstein L. & Neeman M., 6, Circulation-Cardiovascular Imaging, 992-1000, 6, 2013, https://doi.org/10.1161/CIRCIMAGING.113.000828
Characterization of estrogen-receptor-targeted contrast agents in solution, breast cancer cells, and tumors in vivo , Pais A., Biton I. E., Margalit R. & Degani H., 1, Magnetic Resonance in Medicine, 193-206, 70, 2013, https://doi.org/10.1002/mrm.24442
Angiotensin 1-7 as means to prevent the metabolic syndrome lessons from the fructose-fed rat model , Marcus Y., Shefer G., Sasson K., Kohen F., Limor R., Pappo O., Nevo N., Biton I., Bach M., Berkutzki T., Fridkin M., Benayahu D., Shechter Y. & Stern N., 4, Diabetes, 1121-1130, 62, 2013, https://doi.org/10.2337/db12-0792
Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease , Vitner E. B., Farfel-Becker T., Eilam R., Biton I. & Futerman A. H., 6, Brain, 1724-1735, 135, 2012, https://doi.org/10.1093/brain/aws095
Unique in utero identification of fetuses in multifetal mouse pregnancies by placental bidirectional arterial spin labeling MRI , Avni R., Raz T., Biton I. E., Kalchenko V., Garbow J. R. & Neeman M., 2, Magnetic Resonance in Medicine, 560-570, 68, 2012, https://doi.org/10.1002/mrm.23246
Imaging in developmental biology , Vandoorne K., Sapoznik S., Raz T., Biton I. & Neeman M., , , 417-436, , 2011, https://doi.org/10.1007/978-3-642-12945-2_29
In Vivo magnetic resonance imaging of the estrogen receptor in an orthotopic model of human breast cancer , Pais A., Gunanathan C., Margalit R., Biton I. E., Yosepovich A., Milstein D. & Degani H., 24, Cancer Research, 7387-7397, 71, 2011, https://doi.org/10.1158/0008-5472.CAN-11-1226
Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels , Ben David D. O., Pewzner-Jung Y., Brenner O., Laviad E. L., Kogot-Levin A., Weissberg I., Biton I. E., Pienik R., Wang E., Kelly S., Alroy J., Raas-Rothschild A., Friedman A., Bruegger B., Merrill A. H. J. & Futerman A. H., 34, Journal of Biological Chemistry, 30022-30033, 286, 2011, https://doi.org/10.1074/jbc.M111.261206
Neurodegeneration in thiamine deficient rats-A longitudinal MRI study , Dror V., Eliash S., Rehavi M., Assaf Y., Biton I. E. & Fattal-Valevski A., , Brain Research, 176-184, 1308, 2010, https://doi.org/10.1016/j.brainres.2009.10.032