Department of Biomolecular Sciences
PhD position
Size and growth control in neurons and other large cells - do cells sense their own size and how can they do that?
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Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Position available from March 1, 2021
Department of Particle Physics and Astrophysics
PhD position
The Large Array Survey Telescope (LAST) is an under construction
modular and cost-effective survey telescope.
The telescope will be composed of 48 telescopes, each of 28 cm diameter.
The array can act either as a 28 cm telescope, with a huge field of view of 355 deg^2,
or as a single 1.9 m telescope with a 7.4 deg^2 field of view.
When completed, in March 2021, it will be the survey telescope with
the highest grasp (observable volume per unit time) in the world.
Indeed, its grasp will be about four times that of the best available system today.
LAST science cases include:
(1) Searching for optical counterparts of gravitational wave events in order to study the physics of these explosions and the production of the heaviest elements in the Universe;
(2) The early detection of supernovae and transients; a search for rare short-duration events powered by radioactivity; and a search for shock cooling events that enable us to study supernova progenitors;
(3) Developing methods for high precision photometry from the ground,
that are critical for exoplanets detection;
(4) A search for the optical counterparts of short-duration gamma-ray bursts
in order to test the hypothesis that these are related to Neutron Stars merger events; and more.
We are looking for M.Sc./Ph.D. students and postdocs that will lead
some of these science topics with LAST.
Department of Particle Physics and Astrophysics
PhD position
The Large Array Survey Telescope (LAST) is an under construction
modular and cost-effective survey telescope.
The telescope will be composed of 48 telescopes, each of 28 cm diameter.
The array can act either as a 28 cm telescope, with a huge field of view of 355 deg^2,
or as a single 1.9 m telescope with a 7.4 deg^2 field of view.
When completed, in March 2021, it will be the survey telescope with
the highest grasp (observable volume per unit time) in the world.
Indeed, its grasp will be about four times that of the best available system today.
LAST science cases include:
(1) Searching for optical counterparts of gravitational wave events in order to study the physics of these explosions and the production of the heaviest elements in the Universe;
(2) The early detection of supernovae and transients; a search for rare short-duration events powered by radioactivity; and a search for shock cooling events that enable us to study supernova progenitors;
(3) Developing methods for high precision photometry from the ground,
that are critical for exoplanets detection;
(4) A search for the optical counterparts of short-duration gamma-ray bursts
in order to test the hypothesis that these are related to Neutron Stars merger events; and more.
We are looking for M.Sc./Ph.D. students and postdocs that will lead
some of these science topics with LAST.
Department of Chemical and Biological Physics
PhD position
Hybrid quantum devices - combining NV centers in diamond with superconducting resonators via mechanical oscillators
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The QuEST lab is searching for an PhD student for a project combining NV centers in diamond with superconducting resonators via mechanical oscillators. You will fabricate nanobridges in diamond and then characterize them by optical means. The work will be conducted in collaboration with groups in the Technion and Bar-Ilan University in the framework of a Quantum Science and Technologies project funded by the Israel Science Foundation. For more details, please contact: Amit Finkler, amit.finkler@weizmann.ac.il, ext. 2021 or visit our lab on the second floor of the Schmidt building!
Department of Condensed Matter Physics
PhD position
Scanning probe microscopy of quantum and topological states of matter
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Study of quantum and topological states of matter using novel scanning probe microscopy tools. We have recently developed a nano-SQUID (Superconducting Quantum Interference Device) that resides on a very sharp tip and allows imaging of local magnetic fields with single electron spin sensitivity. This device provides also a unique tool for nanoscale cryogenic thermal imaging with 1 ֲµK sensitivity allowing imaging of inelastic electron scattering from a single atomic defect. The project will focus on utilizing these new techniques for investigation of magnetism and dissipation in graphene, superconductors, and topological and quantum states of matter.
Department of Biological Regulation
PhD position
ECM crosslinking in pathology and physiology
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Development and utilisation of probes for analysis of ECM reactions that modulate tissue stiffness and fibrosis in degeneration and tissue regeneration. Development of probes for MRI and multimodal imaging of ECM cross linking.
Department of Molecular Genetics
PhD position
Formation and function of osteoclasts (bone resorbing cells) in vitro and in vivo, in health and in disease.
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Bone degradation by specialized cells (osteoclasts) is a normal process and helps maintain normal bone structure and function; it's absence, as in the genetic disease osteopetrosis, is lethal. Our group studies how specific proteins (tyrosine phosphatases and others) affect production and function of these critical cells, using advanced molecular, cellular, and whole-organism approaches.
Department of Molecular Genetics
PhD position
How do fusing cells stop fusing?
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Cell-cell fusion is an uncommon but essential process in our bodies. While a lot is known about how cell fusion initiates, very little is known about how the process is regulated and eventually terminated when "enough" fusion has occurred. We study these issues in osteoclasts, multi-nucleated cells that degrade bone and which are formed by fusion of monocyte precursor cells. Our studies focus on fusion of osteoclasts from wild-type mice and also from mice carrying mutated forms of sorting nexin 10 (SNX10), which fuse continuously and uncontrollably. Join us to characterize the molecular and cellular mechanisms that regulate osteoclast fusion!
Department of Earth and Planetary Sciences
PhD position
Biosphere-atmosphere interactions. In particular, leaf to canopy gas exchange associated with photosynthesis under stress and the use of novel tracers, such as carbonyl sulfide (COS) and techniques, such as Sun Induced Fluorescence (SIF).
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The successful candidate will join a dynamic and international research team that investigates the interactions between climate change and vegetation. He/She will use novel field techniques to understand photosynthesis response to change, using leaf, branch and ecosystem scales gas exchange of CO2, and carbonyl sulfide (COS; a new atmospheric tracer) and remote sensing (SIF). Background is required in at least one of the following areas: Plant physiology, gas exchange, photosynthesis, atmospheric chemistry, micro-meteorology, operating analytical equipment, willingness to carry out research both in the lab and in the field.
Department of Chemical and Structural Biology
PhD position
The Shalev-Benami lab is looking for a highly motivated PhD candidate for a project involving the cryo-EM characterization of cell-cell communication in the CNS
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The Shalev-Benami lab is looking for a highly motivated PhD candidate for a project involving the cryo-EM characterization of cell-cell communication in the CNS. The ideal candidate will have solid background in biochemistry or structural biology.
Department of Biomolecular Sciences
PhD position
Developing a computational approach to assign mass spectrometry data - a theoretical project.
Department of Biomolecular Sciences
PhD position
For a challenging and exciting project combining biology, chemistry and physics we are seeking for a motivated PhD student. The project involves the development of a new technology for bio-molecular analysis. This is a joint study of Ron Naaman's and Michal Sharon's lb.
Department of Biomolecular Sciences
PhD position
For a challenging and exciting project combining biology, chemistry and physics we are seeking for a motivated PhD student. The project involves the development of a new technology for bio-molecular analysis. This is a joint study of Ron Naaman's and Michal Sharon's lb.
More Information about PhD position
For a challenging and exciting project combining biology, chemistry and physics we are seeking for a motivated PhD student. The project involves the development of a new technology for bio-molecular analysis. This is a joint study of Ron Naaman's and Michal Sharon's lb.
Department of Biological Regulation
PhD position
Available Rotations: 1st,2nd,3rd
Cancer metabolism
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Working on metabolic changes that accompany carcinogenesis in cancer cells, mouse models and human patients for translational relevance.
Department of Computer Science and Applied Mathematics
PhD position
PhD students and Postdocs in the areas of signal processing, machine learning, medical imaging, communications and radar processing
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Host Professor: Yonina Eldar, department of mathematics and computer science, Weizmann Institute Position Description: The Signal Acquisition Measurement Processing and Learning (SAMPL) Lab invites applications for doctoral/postdoctoral positions in the areas of signal processing and machine learning with applications in communications, radar, medical imaging and optical imaging. In the area of medical imaging, the work will be performed in close collaboration with leading hospitals in Israel and abroad. Some of the topics will be in close collaboration with PIs at MIT, Stanford, Princeton and the Broad Institute.
We are looking for thought leaders in these fields who can develop new areas and applications. The balance of work between theory and practice will vary on project-basis, and a successful candidate should be proficient in both aspects. Excellent written and presentation skills in English are an advantage. About SAMPL: The lab focuses on sampling, modeling and processing of continuous-time and discrete-time signals with the aim of extracting as much information as possible using minimal resources to perform various tasks, including communication, radar, medical and optical imaging and biological inference. The lab also develops model-based methods for artificial intelligence (AI) that aid in obtaining increased information from fewer samples, and facilitates the transition from pure theoretical research to the development, design and implementation of prototype systems and clinical studies. Our approach can drastically reduce the sampling and processing rates well below the Nyquist rate, and greatly improve the resolution which can be obtained from a limited number of samples in time, space and frequency. It also paves the way to new technologies such as wireless ultrasound and joint radar and communication systems. The group works closely with several major hospitals in Israel and with research groups at MIT, Stanford, Duke, Princeton and more.
To submit your application, please send an updated CV with 3 letters of recommendation and a cover letter
Department of Molecular Genetics
PhD position
Available Rotations: 3rd
Modeling of human brain development and evolution in health and disease
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We are seeking for students that will apply a multidisciplinary approach to study brain development during evolution and in health and disease.
Department of Molecular Chemistry and Materials Science
PhD position
Several positions available involving multidisciplinary projects studying structure & function of electrode and solid electrolyte materials by novel solid state NMR techniques and the underlying spin physics. Flexible starting date.
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Our group studies how the function of solid materials depend on their composition and structure as well as their interfacial chemistry. We use and develop new diagnostic tools based on magnetic resonance techniques such as solid state NMR and dynamic nuclear polarization (DNP), targeted at the investigation of surface and bulk phenomena in functional materials.
Current research projects include: (i) Developing new approaches for increasing the sensitivity of solid state NMR by polarization transfer from paramagnetic metal ions: this includes theoretical and experimental studies of the underlying spin physics such as the dependence of the polarization transfer process on the metal ion spin properties, the nuclear spin interactions and the electron-nuclear couplings. (ii) Mechanistic study of the functionality of native and artificial surface layers in electrode materials: gaining structural and chemical insight into the surface composition and its effect on ion transport properties across a solid-electrolyte interface. (iii) Elucidating the structural role of dopants on ionic conductivity of solid electrolytes.
Depending on the student's background and interest the projects can involve materials synthesis, device assembly and testing and development of new NMR approaches by theoretical analysis of the spin dynamics.
Department of Plant and Environmental Sciences
PhD position
The Vardi lab is seeking highly motivated candidates to join an exciting project in the field of chemical ecology, focusing on host-pathogen interactions and chemical communication in the ocean.
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The Vardi lab is seeking highly motivated candidates to join an exciting project in the field of chemical ecology, focusing on host-pathogen interactions and chemical communication in the ocean. The project will involve diverse analytical chemistry tools for metabolomics and lipidomics analyses to identify new molecules that mediate virulence and host defence in lab-based model systems and in the marine environment.
Department of Biomolecular Sciences
PhD position
Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli
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Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to enviromental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for potential treatment of cancer, chronic inflammation and neurodegenrative diseases.
Department of Molecular Genetics
PhD position
Intracellular and intercellular mRNA trafficking
Department of Biomolecular Sciences
PhD position
Available Rotations: 1st,2nd,3rd
Investigating the effect of time of the day on exercise performance and related metabolic pathways.
Department of Biomolecular Sciences
PhD position
Available Rotations: 1st,2nd,3rd
Establishing a system for studying the effect of dissolved gases (oxygen/carbon dioxide) on cyanobacteria clock
Department of Biomolecular Sciences
PhD position
Available Rotations: 1st,2nd,3rd
Studying circadian clock communication through exosomes mediated signaling
Department of Biomolecular Sciences
PhD position
Available Rotations: 1st,2nd,3rd
Examining the metabolic consequences and disease states due to misalignment between feeding-activity and disrupted circadian clock
Department of Computer Science and Applied Mathematics
PhD position
Signal processing and communication students? We are looking for you!
The Signal Acquisition, Modeling, Processing, and Learning (SAMPL) lab headed by prof. Yonina Eldar is recruiting Masters and PhD students for cutting edge research in radar, communications, and analog-to-digital conversion.
More Information about PhD position
Candidates with strong electrical engineering or communication systems engineering background are invited to send their CV to Yonina.eldar@weizmann.ac.il
Department of Biomolecular Sciences
PhD position
Spatiotemporal regulation of differential type I interferon signaling in a multicellular context
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Type I interferons (IFNs) are proteins produced and secreted in all higher vertebrates as a result of viral and bacterial attacks. Secreted IFNs bind cell surface receptors initiating a cascade of signals that activate cellular protection machineries against pathogens. In addition, specific immune cells are activated to establish long-term defense of the organism. These properties have been successfully exploited for IFNs to serve as a drug for a variety of complex diseases including viral infections, cancer and multiple sclerosis. Despite the proven success of IFN therapies, their use is currently limited because of their severe side effects. Better understanding of the fundamental principles that determine how IFNs induce their responses in a multicellular context will enable to optimize their use. To this end, we will take advantage of polarized epithelial cell layers and spheroids that mimic the intestine tissue. We will generate genetically engineered cell lines to incorporate a range of fluorescence reporters that monitor IFN signaling at the level of receptor engagement, effector activation and feedback regulation. In collaboration with a German partner we will apply these reporters for volumetric imaging of IFN signaling in the multicellular context using highly advanced microscopy techniques that resolve signaling at the single cell level with utmost spatial and temporal resolution. This highly defined and controlled approach will allow us to unravel the rules of IFN signal activation in tissues upon systemic and local stimulation by IFNs and viruses. Next to a fundamental understanding of signal integration in tissues, this work will also have potential medical implications for improving therapeutic application of IFNs.
Department of Chemical and Biological Physics
PhD position
New scanning methods in magnetic resonance imaging, with applications on ultrahighfield preclinical and clinical research and diagnosis
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Development of new scanning methods in nuclear magnetic resonance spectroscopy and magnetic resonance imaging, with applications in ultrahighfield preclinical and clinical research and diagnosis - including human scanning at 3T and 7T with advanced acquisition techniques
Department of Biomolecular Sciences
PhD position
Molecular signaling in control of immune defense: regulation of programmed cell death and signaling for gene activation.
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Motivated and creative students with background in molecular biology are invited to join our studies of the mechanisms by which signaling by the TNF family contributes to immune defense, to chronic inflammatory and autoimmune diseases and to cancer, and our attempts to derive from this knowledge new ways of therapy.
See our website and list of publications for the range of research subjects that we are exploring and for the range of experimental approaches that we are applying. (http://www.weizmann.ac.il/Biological_Chemistry/scientist/Wallach/home.html).
Department of Neurobiology
PhD position
Ph.D. in visual neuroscience
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Massive work was done to decipher the neural code of the visual information at the retina level. How do retinal targets integrate and process the retinal output is still an unsolved question.
The aim of the project is to reveal how visual information is processed along the main visual pathway. For that, advanced in vivo imaging and electrophysiology techniques will be used in combination with retinal manipulations using pharmacogenetics and other methods.
Computational/engineering background and programming experience are preferable.
Experience with electrophysiology/two-photon imaging is an advantage.
Good social skills and a sense of humor are a must.
Interested candidates with proven academic record are requested to send their CV and contact details of 3 referees to michal.rivlin@weizmann.ac.il
Department of Chemical and Biological Physics
PhD position
Quantum machines at the atomic and molecular scale.
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In this project we will fabricate quantum machines at the atomic and molecular scale and study their operation. This project is expected to shed a new light on the interface between quantum mechanics and thermodynamics.
Department of Chemical and Biological Physics
PhD position
Quantum machines at the atomic and molecular scale.
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Fabrication quantum machines at the atomic and molecular scale and the study of their operation. This project is expected to shed a new light on the interface between quantum mechanics and thermodynamics.
Department of Chemical and Biological Physics
PhD position
Sustainable energy conversion
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In this project we will study the convention of wasted heat to useful electric energy at the molecular scale.
Department of Chemical and Biological Physics
PhD position
Sustainable energy conversion
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Convention of wasted heat to useful electric energy at the atomic and molecular scale.
Department of Chemical and Biological Physics
PhD position
PhD in magnetic resonance imaging and spectroscopy of the human brain
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Our lab develops new methods for trying to understand the biochemistry of the human brain in-vivo, using the Institute's cutting edge 3 Tesla MRI for human research (yes, we scan humans, mostly volunteers). We currently focus on what happens to the brain's chemistry during functional activation. We are at the intersection between physics and neurobiology: We develop the necessary spin physics from theory, through computer simulations, all the way to programming the MRI scanner, running the experiments, and analyzing the data. Prospective students should be independent, inquisitive and have a strong quantitative background. Since imaging is an interdisciplinary field, physicists, physical chemists, computer scientists, neuroscientists and mathematicians can all contribute significantly. Projects will vary depending on candidate's background and interests.
Department of Biomolecular Sciences
PhD position
Applicants with a research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous.
This is a full-time position available from June 2021 for a period of 4 years with a possibility of a further extension subject to funding availability.
Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki.
For any informal inquiries please contact us by email at
neta.regev-rudzki@weizmann.ac.il
Department of Computer Science and Applied Mathematics
PhD position
The Signal Acquisition, Modeling,Processing and Learning (SAMPL) lab headed by Prof. Yonina Eldar at the Weizmann Institute of Science is recruiting PhD, MSc and post-doctoral students for cutting-edge research applying machine learning and deep networks to clinical problems in collaboration with leading hospitals in Israel and abroad.
Candidates with strong algorithmic background are invited to send their CV to yonina.eldar@weizmann.ac.il.
Department of Molecular Genetics
PhD position
Molecular and Cell Biology of RNA viruses
Department of Computer Science and Applied Mathematics
PhD position
The Signal Acquisition, Modeling, Processing and Learning (SAMPL) lab headed by Prof. Yonina Eldar at the Weizmann Institute of Science is recruiting PhD, MSc and post-doctoral students for cutting-edge research applying signal processing and machine learning for communication and radar systems.
Department of Chemical and Biological Physics
PhD position
Developing new neuroimaging methods for studying brain physiology in humans
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Join us and develop exciting new ways of imaging the brain using magnetic resonance imaging (MRI) in humans (yes, we scan people). We develop new methods of studying the way neurons interact with each other, and use those to understand both basic physiology and its breakdown in diseases such as multiple sclerosis and traumatic brain injuries.
PhD projects in the lab focus on one of two goals: First, studying how brain neurotransmitter dynamics varies in response to different stimuli, and in response to plasticity and learning. This is ideal for students who have a more applicative orientation and want to use our unique tools to understand the neurochemical basis of behavior and cognition. Second, developing new methods for measuring neurotransmitter dynamics, and intracellular viscosity. This is suitable for students with a solid quantitative background (chemists, physicists, engineers, applied math/computer scientists), and involves a mixture of physics, algorithm development and signal processing. We're very good at integrating people from varying backgrounds, as most things are learned "on the job" as you go along.
Department of Molecular Genetics
PhD position
Chameleons, copepods, fish, and many other organisms, use organic crystals for an astonishing variety of optical functions. These crystals are formed by specialized cells, in which remarkable control over crystal shape, size, and assembly is obtained using strategies that are beyond the state of the art in materials science. While these cells were identified many years ago, almost nothing is known about their biology, particularly the cellular processes involved in organic crystal formation. We use biological tools and physical and chemical methodologies to study the processes organisms use to produce either optically functional or pathological bio-organic crystals. Our primary model organisms for these studies are zebrafish and medaka.
