Design principles of biological circuits

  • Miri Adler, Uri Alon
    , (2018) [PDF]
  • Adler M; Szekely P; Mayo A; Alon U
    , (2017) [PDF]
    • Out of a million possible circuits, only very few show optimal fold change detection - possibly explaining why only a few circuit designs recur across biology.
    • Cell Systems preview
  • Towbin BD; Korem Y; Bren A; Doron S; Sorek R; Alon U;
    , (2017) [PDF]

    Bacteria use a rule of thumb to optimize growth rate, which often works but sometimes fails

  • Omer Karin, Uri Alon
    , (2017) [PDF]

    Biphasic control, where a signal is toxic at both high and low levels, eliminates mis-sensing mutants at the cost of decreased resilience to dynamic perturbations, with implications for different diseases.

  • Karin O; Swisa A; Glaser B; Dor Y; Alon U;
    , (2016) [PDF]

    Dynamical compensation provides robustness of the entire output trace robust to variation in key parameters and appears in endocrine and neuronal circuits

  • Rothschild, D; Dekel, E; Hausser, J; Bren, A; Aidelberg, G; Szekely, P; Alon, U
    , 10:e1003602 (2014) [PDF]
  • Yuval Hart, Shlomit Reich-Zeliger, Yaron E. Antebi, Irina Zaretsky, Avraham E. Mayo, Uri Alon, Nir Friedman
    , (2014) [PDF]
  • Adler, M; Mayo, A; Alon, U
    , 10:e1003781 (2014) [PDF]
  • Aidelberg G, Towbin BD, Rothschild D, Dekel E, Bren A, Alon U,
    , 8:133 (2014) [PDF]
  • Anat Bren; Yuval Hart; Erez Dekel; Daniel Koster; Uri Alon
    , 7:000007820 (2013) [PDF]
  • Yuval Hart; Avraham E. Mayo; Oren Shoval; Uri Alon
    , 8:000018118 (2013) [PDF]
  • Hart Y, Alon U
    , (2013) [PDF]
  • Leeat Keren; Ora Zackay; Maya Lotan-Pompan; Uri Barenholz; Erez Dekel; Vered Sasson; Guy Aidelberg; Anat Bren; Danny Zeevi; Adina Weinberger; Uri Alon; Ron Milo; Eran Segal
    , 9:000021320 (2013) [PDF]
  • Madar D, Dekel E, Bren A, Zimmer A, Porat Z, Alon U,
    , 7:136 (2013) [PDF]

    Commentary by Daniel Schultz and Roy Kishony

  • Olin K. Silander; Nela Nikolic; Alon Zaslaver; Anat Bren; Ilya Kikoin; Uri Alon; Martin Ackermann
    , 8:000036466 (2012)
  • Yuval Hart; Yaron E. Antebi; Avraham E. Mayo; Nir Friedman; Uri Alon
    , 109:000018115 (2012) [PDF] [SOM]
  • Vered Sasson; Irit Shachrai; Anat Bren; Erez Dekel; Uri Alon
    , 46:000033772 (2012) [PDF] [SOM]
  • Oren Shoval; Uri Alon; Eduardo Sontag
    , 10:000036279 (2011)
  • Yuval Hart; Avraham E. Mayo; Ron Milo; Uri Alon
    , 5:000018117 (2011) [PDF]
  • Yuval Hart; Daniel Madar; Jie Yuan; Anat Bren; Avraham E. Mayo; Joshua D. Rabinowitz; Uri Alon
    , 41:000018116 (2011) [PDF]
  • Madar D, Hart Y, Yuan J, Bren A, Mayo AE, Rabinowitz JD, Alon U,
    , (2011)
  • Guy Shinar, Martin Feinberg
    , (2010) [PDF]
  • Irit Shachrai; Alon Zaslaver; Uri Alon; Erez Dekel
    , 38:000035032 (2010) [PDF]
  • Oren Shoval; Lea Goentoro; Yuval Hart; Avi Mayo; Eduardo Sontag; Uri Alon
    , 107:000036280 (2010) [PDF]
  • Elad Noor; Eran Eden; Ron Milo; Uri Alon
    , 39:000028865 (2010) [PDF]
  • Guy Shinar; Uri Alon; Martin Feinberg
    , 69:000036033 (2009) [PDF]
  • Guy Shinar; Joshua D. Rabinowitz; Uri Alon
    , 5:000036041 (2009) [PDF]
  • Zaslaver, A; Kaplan, S; Bren, A; Jinich, A; Mayo, A; Dekel, E; Alon, U; Itzkovitz, S
    , (2009) [PDF]
  • Lea Goentoro; Oren Shoval; Marc W. Kirschner; Uri Alon
    , 36:000015713 (2009) [PDF]
  • Guy Shinar; Ron Milo; Maria Rodriguez Martinez; Uri Alon
    , 104:000036040 (2007) [PDF]
  • Guy Shinar; Erez Dekel; Tsvi Tlusty; Uri Alon
    , 103:000036034 (2006) [PDF]
  • Zaslaver, A; Bren, A; Ronen, M; Itzkovitz, S; Kikoin, I; Shavit, S; Liebermeister, W; Surette, MG; Alon, U
    , (2006) [PDF]
  • Zaslaver, A; Mayo, AE; Rosenberg, R; Bashkin, P; Sberro, H; Tsalyuk, M; Surette, MG; Alon, U
    , (2004) [PDF]

    See features in:

    • Nature Reviews Genetics : [PDF]
    • Journal of Cell Biology : [PDF]
  • Kalir S, Alon U
    , (2004) [PDF]
  • N Rosenfeld; Uri Alon
    , 329:000032802 (2003) [PDF]
  • Yaakov Setty; AE Mayo; MG Surette; Uri Alon
    , 100:000034976 (2003) [PDF]
  • N Rosenfeld; MB Elowitz; Uri Alon
    , 323:000032803 (2002) [PDF]
  • M Ronen; R Rosenberg; BI Shraiman; Uri Alon
    , 99:000032680 (2002) [PDF]

    See also JCB news:  [PDF]

  • Shiraz Kalir; J McClure; K Pabbaraju; C Southward; M Ronen; S Leibler; MG Surette; Uri Alon
    , 292:000020396 (2001) [PDF]
  • Alon U, Surette MG, Barkai N, Leibler S.
    , (1999) [PDF]