September 20, 1989 - September 20, 2022

  • Date:16SundayJune 2019

    A Comprehensive Mechanistic Biological Theory of Brain Function

    More information
    Time
    11:00
    Location
    Camelia Botnar Building
    Botnar Auditorium
    Lecturer
    Prof. Ari Rappoport
    The Rachel and Selim Benin School of Computer Science and Engineering The Hebrew University of Jerusalem
    Organizer
    Department of Neurobiology
    Contact
    DetailsShow full text description of Short Bio: Ari Rappoport is a Full Professor of Computer Sci...»
    Short Bio: Ari Rappoport is a Full Professor of Computer Science at the Hebrew University. His CS area of expertise is Natural Language Processing, where he focuses on semantic representations. He started developing his brain theory in 2010, completing it at the end of 2017.

    Host: Prof. Ehud Ahissar ehud.ahissar@weizmann.ac.il tel: 4574

    For assistance with accessibility issues, please contact naomi.moses@weizmann.ac.il
    AbstractShow full text abstract about The brain is the target of intense scientific study, yet cur...»
    The brain is the target of intense scientific study, yet currently there is no theory of how it works at the system level. In this talk I will present the first such theory. The theory is biological and concrete, showing how motor and cognitive capacities arise from relatively understood biological entities. The main idea is that brain function is managed by a response (R) process whose structure is very similar to the process guiding the immune system. The brain has two instances of the R process, managing execution and need satisfaction. The stages of the execution process are implemented by different neural circuits, explaining the roles of cortical layers, the different types of inhibitory interneurons, hippocampal fields and basal ganglia paths. The stages of the need process are supported by different molecular agents, explaining the roles of dopamine, serotonin, ACh, opioids and oxytocin. The same execution process gives rise to hierarchical motor sequences, language, and imagery, while the need process explains feelings/emotions and consciousness in a mechanistic manner. The theory includes some aspects that are dramatically different from accepted accounts, e.g., the roles of basal ganglia paths, serotonin and opioids. The scope of the addressed phenomena is large, but they are all explained quite simply by the R process.

    Lecture