February 07, 1996 - February 07, 2029
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Date:09WednesdayMay 2018
Developmental Club Series 2017-2018
More information| Time | 10:00 - 10:00 |
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| Title | Spanning the Scales: Computer modelling of growth and form in the developing limb bud |
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| Location | Arthur and Rochelle Belfer Building for Biomedical Research |
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| Lecturer | Dr. James Sharpe
Head of Outstation and Senior Scientist at EMBL, Barcelona, Spain |
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| Abstract | Show full text abstract about The vertebrate limb bud is a classical model system for deve...» The vertebrate limb bud is a classical model system for developmental biology – with the advantage of having been studied for many decades. Despite this, and despite its relatively simple shape, a consensus model of its physical morphogenesis has not been reached. I will introduce our own hypothesis on limb bud morphogenesis – convergent-extension coupled with tissue growth – and contrast it to previous ideas. I will introduce a 3D dynamical model which captures this hypothesis (a Cellular Potts Model) and also discuss our ongoing improvements to these simulations.
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