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Prof. Michal Neeman
MRI of angiogenesisCollaboration with: Prof Nava Dekel, Weizmann Prof Lucio Frydman, Weizmann Prof Joel Garbow, Washington Univ. St Louis Prof Silvio Aime, Univ Torino Prof Simcha Yagel and Dr Ofer Behavior, Hadassah Medical Center Prof Michal Kovo, Meir Medical Center Prof Tal Raz, HUJCOVID-19 in pregnancyPlacenta structure and functionVascular remodelling in reproduction and developmentProtocols, Reporter genes and Probes for molecular imaging
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Dr. Filipe Andre Natalio
Material Farming: Where plant meet material sciencesCollaboration with: Dr. Michaela Eder and Prof. Peter Fratzl (Max Planck Institute of Colloids and Interfaces, Golm, Germany)We are interested in combining plant and material sciences to harness plants as biofactories to produce complex biological materials with tailored properties, with particular focus on cotton. Cotton is the global leading natural fiber involving 250 million around the world from farmer to retailer. Combining chemical synthesis of cotton fibers building blocks and a comprehensive understanding of the underlying biochemical and physiological mechanisms, we can produce cotton fibers with tailored properties such as increased hydrophobicity (think about your rain jacket). We coined this approach as Material Farming. This approach is an opportunity to implement sustainable alternative(s) to produce functional fibers overcoming the chemical fiber post-processing known to generate large amounts of chemical waste hazardous to the enviroment and humans. Finally, our approach will allow us to harness higher organisms' complexity, such as cotton plants, which can change how we currently think about the design of complex biological materials, plant sciences, and their physiology and biochemistry with a profound impact on the future of cotton-related industries.Scientific Archaeology - Artificial Inteligencemeets ArchaeologyCollaboration with: Prof. Michael Chazan (University of Toronto) Dr. Liora Kolska Horowtiz (Hebrew University)We explore hidden signatures from the archaeological artifacts using artificial intelligence (AI) to infer human behavior. Our research explores cultural evolution and transmission in the Levant, the origin of domestication of cattle in the Fertile Crescent, and the relations between hominins and fire use. We combine the dozens of thousand unearthed and available archaeological remains (pottery, statues, stone tools, etc.) with AI to infer new relations between cultures - the known of the unknowns - while pinpointing the origin of revolutionary technologies their dispersion and implications to the cultural transmission continuum. We investigate the domestication of cattle, and their use for cultures was originated in the Fertile Crescent. What if older organic artifacts (plow) perished and the use of animals for plowing started earlier? We use AI combined with ancient cattle bones to find morphological changes induced by plowing and inform whether this behavior started earlier, implying a new conceptual understanding of a revolutionary technology that changed our way of living until today. Pyrotechnology is one of the most revolutionary advances in human evolution initiated about 2 million years ago. This technology allowed, for example, the cooking of food, changing our biochemistry (e.g., more energetic intake) and physiology (e.g., larger brain size). We develop new AI-based methodologies applied to flint stone tools (the most durable artifacts) that act as a thermometer to infer hominin relations with fire deep in time.
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Prof. Ron Naaman
Spin selectivity in electrons transmission through chiral moleculesCollaboration with: Yossi Paltiel, Hebrew University David H. Waldeck, University of Pittsburghm USA Claudio Fontanessi, Modena University, Italy E. W. Meijer, Eindhoven, Netherland Michael Therien, Duke University, USA Moh El Naggar, USC, USA Jonas Fransson, Uppsala, Swedenelectron transfer in bio-moleculesspin selective electron transferspin dependent electrochemistryspintronics with chiral moleculesenantio-selective interactionSpin effect in water splitting
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Prof. David Mukamel
Systems with long-range interactionsCollaboration with: S. Ruffo A. CampaCollective phenomena in systems far from thermal equilibrium.Collaboration with: S. Majumdar G. Schehr M. Barma A. KunduCoarsening processes and slow dynamics.Systems with long range interactions
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Dr. David Mross
Fractional quantum Hall effectNon-Abelian states at filling factor 5/2Composite Fermi liquids and particle-hole symmetryEdge-states and disorder effectsQuantum magnetismQuantum spin liquids in frustrated magnetsUnconventional quantum phase transitionsDualitiesApplications of dualities in condensed matter physicsDerivation of new dualities through coupled-wire constructions
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Prof. Edna Mozes
Systemic lupus erythematosus (SLE): Induction and development in various animal models.The role of various cell types (APC, T, B) and cytokines in the pathogenesis of autoimmune diseases.The status and role of T regulatory cells in autoimmune diseases.Specific immunomodulation of the autoimmune diseases, Systemic lupus erythematous and Sjogren Syndrome by a synthetic, tolerogenic peptide.Collaboration with: Prof. Zev Sthoeger, Kaplan Medical Center.Elucidation of the mechanisms (effects on main pathways, cell types, cytokines and other pathogenic molecules) by which the tolerogenic peptide ameliorates autoimmune disease manifestations in animal models and in patients with SLE and Sjogren Syndrome.Development of the tolerogenic peptide as a novel specific drug for the treatment of SLE and Sjogren Syndrome.
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Prof. David Mirelman
Molecular pathogenesis of the human intestinal parasite <I>Entamoeba histolytica</I>.Collaboration with: Rivka BrachaMolecular biology and genome organization in the lower eukaryot <I>Entamoeba histolytica</I>.Selective inhibition of expression of virulence genes by Antisense RNA.Transcriptional epigenetic gene silencing mechanismsPathogenesis of AmoebiasisDevelopment of vaccine against <I>Entamoeba histolytica</I>.Mode of action and therapeutical potential of Allicin from GarlicCollaboration with: Aharon Rabinkov, Elena AppelUses of derivatives of Allicin against hypertension and obesityAntifungal delivery system which produces in situ toxic allicin moleculesA delivery system for the in-vivo killing of cancer cells by Allicin
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