-
Prof. Varda Rotter
Molecular mechanisms controlling the expression of p53 in normal cells and its deregulation in cancer cellsInvolvement of p53 in cell differentiation and apoptosis: <I>in vivo</I> and in vitro models.Cellular proteins that specifically complex with the p53 protein.Cellular proteins that are induced upstream or downstream to the p53 protein following genotoxic stress.
Homepage
-
Prof. Vered Rom-Kedar
Hamiltonian systems - theory and applicationsCollaboration with: M. Radnovic, A. Rapoport, E. Shlizerman, D. TuraevNear-integrable systemsThe Boltzmann ergodic hypothesis and soft billiards.Chaotic scattering.Resonant surface waves.Perturbed nonlinear Schrodinger equation.Mathematical models of the hematopoietic system and their medical implicationsCollaboration with: R. Malka, E. Shochat.Chaotic mixing of fluid flowsCollaboration with: R. Aharon, H. Gildor
Homepage
-
Prof. Michel Revel
Applications of IL-6 Chimera and Interferon-beta in neurology, hematopoiesis, and oncology.Collaboration with: J. ChebathInterleukin-6 Chimera, a superactivator of the gp130 receptor system: role in nerve myelination, neuroprotection and in the development of neuro-glial cells from embryonic tissues and stem cells.Collaboration with: J. ChebathTransdifferentiation of neural crest cell derived melanoma into myelinating Schwann cell. Genes controlling cell growth, differentiation, melanogenesis and synthesis of myelin proteins.Collaboration with: J. Chebath
-
Prof. Yair Reisner
Immature dendritic cells: investigating a novel granule mediated killing mechanism and the therapeutic potential for the prevention of Graft versus Host Disease.Crossing allogeneic and xenogeneic barriers by growing organs in-vivo from embryonic tissues : potential curative approaches for diabetes, hemophilia and lung diseases.Hematopoietic size control: A novel role for coagulation cascade factors in regulating the interplay between dynamic bone structure and long term survival and mobilization of hematopoietic stem cells.Developing a protocol for the production of human central memory CD8 T cells, to induce tolerance in allogeneic stem cell transplantation.Investigating the use of activated CD8 T cells as novel cell therapy for the treatment of autoimmune diseases.Role and mechanism of tolerance induction by activated CD8 T cells: A novel cell therapy for chimerism induction, stem cell transplant engraftment and enhanced Graft versus Lymphoma / Leukemia effect.
-
Prof. Orly Reiner
Formation of the brain structure in human is a complex process. One of the most striking features of the human brain is characteristic convolutions. These convolutions are lacking in a severe human brain malformation known as lissencephaly (smooth brain).Identification of genes that are downstream to Lis1 mutation using microarray technology.Study of LIS1 and DCX functions through characterization of protein interactionsAnalysis of the developmental function of LIS1, DCX and Doublecortin-like-kinase using gene targeting in the mouse.Functional Analysis of Genes Involved in Lissencephaly.
Homepage
