• Picture of Dr. Liran Shlush

    Dr. Liran Shlush

    Clonal dynamics of aging hematopoiesis in humans
    Collaboration with:  Amos Tanay Omar abdel Wahab Jon Dick Mark Minden Hofer Thomas Elisa Laurenti Paaladinesh Thavendiranathan Hartmut Geiger Benny Geiger Dennis Kim Müller-Tidow, Carsten Yinon Ben Neria
    Understanding the functional effects of preleukaemic mutations on human haematopoietic stem cells
    Microhomology-mediated end joining (MMEJ) DNA repair in pre-leukemic hematopoietic stem cells
    Prevention of myeloid malignancies among carriers of spliceosome mutations
    Age-related clonal hematopoiesis and its link to age-related changes in the bone marrow microenvironment
    Multi-dimensional analysis and the human aging blood system

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  • Prof. Ben-Zion Shilo

    Deciphering embryonic development
  • Picture of Prof. Yoram Shechter

    Prof. Yoram Shechter

    Mechanism of insulin action: Post-binding events in insulin action
    Post-receptor agents mimicking insulin.
    Effect of vanadium <I>in vivo</I> and <I>in vitro</I>.
    Role of protein tyrosine kinases and protein phosphotyrosine phosphatases in insulin effects.
    Inhibitors of tyrosine kinases.
    Chemical modifications of peptides and protein drugs.
    Novel technologies to prolong life time of peptide and protein drugs.

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  • Picture of Prof. Yosef Shaul

    Prof. Yosef Shaul

    The molecular basis of virus-host cell interaction. How HBV modifies cell behavior.
    Collaboration with:  Charles Rice the Rockefeller university
    proteasomes as a target in cancer therapy
    proteasome composition, dynamics, function and regulation and various conditions.
    proteasomal degradation of intrinsically disordered proteins (IUP or IDP). the concept of degradation by default

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  • Picture of Prof. Michal Sharon

    Prof. Michal Sharon

    Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.
    Developing novel methodological approaches for structural mass spectrometry
    Structure-function relationship of the signalosome complex
    Investigation of the 20S ubiquitin-independent degradation pathway

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  • Picture of Prof. Ehud Shapiro

    Prof. Ehud Shapiro

    Laying the Biological, Computational and Architectural Foundations for Human Cell Lineage Discovery
    Collaboration with:  E. Shapiro, V. Adalsteinsson, H. Brodi, M. Minden, R. Halaban, C. Klein, M. Meyerson, C. Wu, T. Zukerman, R. Shalom

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  • Picture of Prof. Abraham Shanzer

    Prof. Abraham Shanzer

    Supramolecular chemistry
    Biomimetic ion binders, diagnostic tools in imaging technologies (fluorescent probes) and potential therapeutic agents. Synthesis, using classical and combinatorial chemistry methods and evaluation.
    Synthesis and properties of molecular based devices; molecular sensors, switches and logical gates for application in nanotechnology.
    Surface bound functional assemblies.

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  • Picture of Prof. Adi Shamir

    Prof. Adi Shamir

    Cryptography, cryptanalysis, electronic money, smartcard security, internet security, complexity theory, the design and analysis of algorithms.

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