Characterization of LTBP2 mutation causing mitral valve prolapse , Shpitzen S., Rosen H., Ben-Zvi A., Meir K., Levin G., Gudgold A., Ben Dor S., Haffner R., Zwas D. R., Leibowitz D., Slaugenhaupt S. A., Banin E., Mizrachi R., Obolensky A., Levine R. A., Gilon D., Leitersdorf E., Tessler I., Reshef N. & Durst R., 1, European Heart Journal Open, , 5, 2025, https://doi.org/10.1093/ehjopen/oeae106
Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder , Shomer I., Mor N., Raviv S., Budick-Harmelin N., Matchevich T., Avkin-Nachum S., Rais Y., Haffner-Krausz R., Haimovich A., Ziv A., Fluss R., Ben-Ze'ev B., Heimer G., Silachev D. N., Katanaev V. L. & Dominissini D., 1, Molecular Therapy Nucleic Acids, , 36, 2025, https://doi.org/10.1016/j.omtn.2024.102432
Molecular insights into the unique properties of the blood-circulating proteasome , Leushkin Y., Morgenstern D., Ben-Dor S., Haffner-Krausz R., Zittlau K., Ben-Nissan G. & Sharon M., 1, Journal of Extracellular Biology, , 4, 2025, https://doi.org/10.1002/jex2.70034
Improving laboratory animal genetic reporting: LAG-R guidelines , Teboul L., Amos-Landgraf J., Benavides F. J., Birling M. C., Brown S. D., Bryda E., Bunton-Stasyshyn R., Chin H. J., Crispo M., Delerue F., Dobbie M., Franklin C. L., Fuchtbauer E. M., Gao X., Golzio C., Haffner R., Hérault Y., Hrabe de Angelis M., Lloyd K. C. & Magnuson T. R., , Nature Communications, , 15, 2024, https://doi.org/10.1038/s41467-024-49439-y
Establishing a Mouse Genotyping Core Facility Based on Automation, High-resolution Melting Analysis, and Purpose-developed MATLAB Applications for Sample Tracking, Data Analysis, and Report Generation , Dafni H., Levi K., Eldad M. C., Shaul M., Oren R., Alyagor L., Stettner N., Harmelin A. & Haffner-Krausz R., 4, Comparative Medicine, 263-273, 74, 2024, https://doi.org/10.30802/AALAS-CM-24-000014
Tackling Tissue Macrophage Heterogeneity by SplitCre Transgenesis , Boura-Halfon S., Haffner-Krausz R., Ben-Dor S., Kim J. S. & Jung S., , , 481-503, , 2024, https://doi.org/10.1007/978-1-0716-3437-0_32
Siah3 acts as a physiological mitophagy suppressor that facilitates axonal degeneration , Abraham O., Ben-Dor S., Goliand I., Haffner-Krausz R., Colaiuta S. P., Kovalenko A. & Yaron A., 857, Science Signaling, , 17, 2024, https://doi.org/10.1126/scisignal.adn5805
Tuft cells and fibroblasts promote thymus regeneration through ILC2-mediated type 2 immune response , Nevo S., Frenkel N., Kadouri N., Gome T., Rosenthal N., Givony T., Avin A., Peligero Cruz C., Kedmi M., Lindzen M., Ben Dor S., Damari G., Porat Z., Haffner-Krausz R., Keren-Shaul H., Yarden Y., Munitz A., Leshkowitz D., Goldfarb Y. & Abramson J., 91, Science Immunology, , 9, 2024, https://doi.org/10.1126/sciimmunol.abq6930
Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation , Sapoznikov A., Kozlovski S., Levi N., Feigelson S. W., Regev O., Davidzohn N., Ben-Dor S., Haffner-Krausz R., Feldmesser E., Wigoda N., Petrovich-Kopitman E., Biton M. & Alon R., 8, Cell Reports, , 42, 2023, https://doi.org/10.1016/j.celrep.2023.112864
Thymic mimetic cells function beyond self-tolerance , Givony T., Leshkowitz D., Del Castillo D., Nevo S., Kadouri N., Dassa B., Gruper Y., Khalaila R., Ben-Nun O., Gome T., Dobeš J., Ben-Dor S., Kedmi M., Keren-Shaul H., Heffner-Krausz R., Porat Z., Golani O., Addadi Y., Brenner O., Lo D. D., Goldfarb Y. & Abramson J., 7981, Nature, 164172, 622, 2023, https://doi.org/10.1038/s41586-023-06512-8
Kinesin family member 2A gates nociception , Dey S., Barkai O., Gokhman I., Suissa S., Haffner-Krausz R., Wigoda N., Feldmesser E., Ben-Dor S., Kovalenko A., Binshtok A. & Yaron A., 10, Cell Reports, , 42, 2023, https://doi.org/10.1016/j.celrep.2023.113257
A partial form of AIRE deficiency underlies a mild form of autoimmune polyendocrine syndrome type 1 , Oftedal B. E., Berger A. H., Bruserud Ø., Goldfarb Y., Sulen A., Breivik L., Hellesen A., Ben-Dor S., Haffner-Krausz R., Knappskog P. M., Johansson S., Wolff A. S., Bratland E., Abramson J. & Husebye E. S., 21, The Journal of Clinical Investigation, , 133, 2023, https://doi.org/10.1172/JCI169704
Transcriptional regulation of the thymus master regulator Foxn1 , Kadouri N., Giladi T., Katz S., Hey J., Ben-Dor S., Damari G., Dassa B., Dobes J., Dieter W., Bähr M., Paulsen M., Haffner-Krausz R., Mall M. A., Plass C., Kafka Y. & Abramson J., 74, Science Immunology, , 7, 2022, https://doi.org/10.1126/sciimmunol.abn8144
Cognate microgliaT cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology , Haimon Z., Frumer G. R., Kim J., Trzebanski S., Haffner-Krausz R., Ben-Dor S., Porat Z., Muschaweckh A., Chappell-Maor L., Boura-Halfon S., Korn T. & Jung S., 12, Nature Immunology, 1749-1762, 23, 2022, https://doi.org/10.1038/s41590-022-01360-6
Brain pathology and cerebellar purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease , Pewzner-Jung Y., Joseph T., Blumenreich S., Vardi A., Ferreira N. S., Cho S. M., Eilam R., Tsoory M., Biton I. E., Brumfeld V., Haffner-Krausz R., Brenner O., Sharabi N., Addadi Y., Salame T. M., Rotkopf R., Wigoda N., Yayon N., Merrill A. H., Schiffmann R. & Futerman A. H., , Progress in Neurobiology, , 197, 2021, https://doi.org/10.1016/j.pneurobio.2020.101939
BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development , Heinemann-Yerushalmi L., Bentovim L., Felsenthal N., Vinestock R. C., Michaeli N., Krief S., Silberman A., Cohen M., Ben-Dor S., Brenner O., Haffner-Krausz R., Itkin M., Malitsky S., Erez A. & Zelzer E., 8, Developmental Cell, 1182-1194.e6, 56, 2021, https://doi.org/10.1016/j.devcel.2021.03.007
Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation , Goldfarb Y., Givony T., Dobeš J., Kadouri N., Zalayat I., Peligero-Cruz C., Damari G., Dassa B., Ben-Dor S., Gruper Y., Oftedal B. E., Bratland E., Erichsen M. M., Berger A., Avin A., Nevo S., Haljasorg U., Kuperman Y., Ulman A., Porat Z., Haffner-Krausz R., Atasoy U., Leshkowitz D., Husebye E. S. & Abramson J., 11, Journal of Experimental Medicine, , 218, 2021, https://doi.org/10.1084/jem.20201076
The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization , Doron E., Koppel I., Abraham O., Rishal I., Smith T. P., Buchanan C. N., Sahoo P. K., Kadlec J., Oses-Prieto J. A., Kawaguchi R., Alber S., Zahavi E. E., Di Matteo P., Di Pizio A., Song D. A., Okladnikova N., Gordon D., Ben-Dor S., Haffner-Krausz R., Coppola G., Burlingame A. L., Jungwirth P., Twiss J. L. & Fainzilber M., 20, EMBO Journal, , 40, 2021, https://doi.org/10.15252/embj.2020107158
TT2019 meeting report on the 15th Transgenic Technology Meeting in Kobe, Japan CRISPR drives new frontiers in animal models: CRISPR drives new frontiers in animal models , Haffner-Krausz R., 5-6, Transgenic Research, 637-643, 28, 2019, https://doi.org/10.1007/s11248-019-00164-z
Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases , Sapir T., Levy T., Kozer N., Shin I., Zamor V., Haffner-Krausz R., McGlade J. C. & Reiner O., 9, Cerebral Cortex, 3115-3128, 28, 2018, https://doi.org/10.1093/cercor/bhx180
Developmental activities of the complement pathway in migrating neurons , Gorelik A., Sapir T., Haffner-Krausz R., Olender T., Woodruff T. M. & Reiner O., , Nature Communications, , 8, 2017, https://doi.org/10.1038/ncomms15096
A role for TENM1 mutations in congenital general anosmia , Alkelai A., Olender T., Haffner-Krausz R., Tsoory M. M., Boyko V., Tatarskyy P., Gross-Isseroff R., Milgrom R., Shushan S., Blau I., Cohn E., Beeri R., Levy-Lahad E., Pras E. & Lancet D., 3, Clinical Genetics, 211-219, 90, 2016, https://doi.org/10.1111/cge.12782
Unraveling chemokine and chemokine receptor expression patterns using genetically engineered mice , Yona S., Kim K., Haffner R. & Jung S., , , 129-144, , 2013, https://doi.org/10.1007/978-1-62703-426-5_8
Functional phenotyping of the maternal albumin turnover in the mouse placenta by dynamic contrast-enhanced MRI , Plaks V., Sapoznik S., Berkovitz E., Haffner-Krausz R., Dekel N., Harmelin A. & Neeman M., 3, Molecular Imaging and Biology, 481-492, 13, 2011, https://doi.org/10.1007/s11307-010-0390-1
Survival and size are differentially regulated by placental and fetal PKBalpha/AKT1 in mice , Plaks V., Berkovitz E., Vandoorne K., Berkutzki T., Damari G. M., Haffner R., Dekel N., Hemmings B. A., Neeman M. & Harmelin A., 3, Biology of Reproduction, 537-545, 84, 2011, https://doi.org/10.1095/biolreprod.110.085951
CKIα ablation highlights a critical role for p53 in invasiveness control , Elyada E., Pribluda A., Goldstein R. E., Morgenstern Y., Brachya G., Cojocaru G., Snir-Alkalay I., Burstain I., Haffner-Krausz R., Jung S., Wiener Z., Alitalo K., Oren M., Pikarsky E. & Ben-Neriah Y., 7334, Nature, 409-413, 470, 2011, https://doi.org/10.1038/nature09673
Nek7 kinase targeting leads to early mortality, cytokinesis disturbance and polyploidy , Salem H., Rachmin I., Yissachar N., Cohen S., Amiel A., Haffner R., Lavi L. & Motro B., 28, Oncogene, 4046-4057, 29, 2010, https://doi.org/10.1038/onc.2010.162
Caspase-8 serves both apoptotic and nonapoptotic roles , Kang T., Ben Moshe T., Varfolomeev E. E., Pewzner-Jung Y., Yogev N., Jurewicz A., Waisman A., Brenner O., Haffner R., Gustafsson E., Ramakrishnan P. & Wallach D., 5, Journal of Immunology, 2976-2984, 173, 2004, https://doi.org/10.4049/jimmunol.173.5.2976
Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body , Li X., Chen Y., Scheele S., Arman E., Haffner-Krausz R., Ekblom P. & Lonai P., 4, Journal of Cell Biology, 811-822, 153, 2001, https://doi.org/10.1083/jcb.153.4.811
Expression of Fgfr2 in the early mouse embryo indicates its involvement in preimplantation development , Haffner-Krausz R., Gorivodsky M., Chen Y. & Lonai P., 1-2, Mechanisms of Development, 167-172, 85, 1999, https://doi.org/10.1016/S0925-4773(99)00082-9
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis , Arman E., Haffner-Krausz R., Gorivodsky M. & Lonai P., 21, Proceedings of the National Academy of Sciences of the United States of America, 11895-11899, 96, 1999, https://doi.org/10.1073/pnas.96.21.11895
Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase , Lallemand Y., Luria V., Haffner-Krausz R. & Lonai P., 2, Transgenic Research, 105-112, 7, 1998, https://doi.org/10.1023/A:1008868325009
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development , Arman E., Haffner-Krausz R., Chen Y., Heath J. & Lonai P., 9, Proceedings of the National Academy of Sciences of the United States of America, 5082-5087, 95, 1998, https://doi.org/10.1073/pnas.95.9.5082
A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1 , Ruaro E., Collavin L., DelSal G., Haffner R., Oren M., Levine A. & Schneider C., 9, Proceedings of the National Academy of Sciences of the United States of America, 4675-4680, 94, 1997, https://doi.org/10.1073/pnas.94.9.4675
Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells , Bacus S., Yarden Y., Oren M., Chin D., Lyass L., Zelnick C., Kazarov A., Toyofuku W., GrayBablin J., Beerli R., Hynes N., Nikiforov M., Haffner R., Gudkov A. & Keyomarsi K., 12, Oncogene, 2535-2547, 12, 1996,
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis , Hiebert S. W., Packham G., Strom D. K., Haffner R., Oren M., Zambetti G. & Cleveland J. L., 12, Molecular and Cellular Biology, 6864-6874, 15, 1995, https://doi.org/10.1128/MCB.15.12.6864
Biochemical properties and biological effects of p53 , Haffner R. & Oren M., 1, Current Opinion in Genetics and Development, 84-90, 5, 1995, https://doi.org/10.1016/S0959-437X(95)90058-6
Loss of p53 function through PAX-mediated transcriptional repression , Stuart E. T., Haffner R., Oren M. & Gruss P., 22, EMBO Journal, 5638-5645, 14, 1995, https://doi.org/10.1002/j.1460-2075.1995.tb00251.x
Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal , Gottlieb E., Haffner R., Von Rüden T., Wagner E. F. & Oren M., 6, EMBO Journal, 1368-1374, 13, 1994, https://doi.org/10.1002/j.1460-2075.1994.tb06390.x
A role for CdxA in gut closure and intestinal epithelia differentiation , Frumkin A., Pillemer G., Haffner R., Tarcic N., Gruenbaum Y. & Fainsod A., 2, Development (Cambridge), 253-263, 120, 1994, https://doi.org/10.1242/dev.120.2.253
WILD-TYPE P(53) ACTIVITY CONTRIBUTES TO DEPENDENCE ON HEMATOPOIETIC SURVIVAL FACTORS , GOTTLIEB E., HAFFNER R., YONISHROUACH E., VONRUDEN T., WAGNER E. & Oren M., , Apoptosis, 31-45, 5, 1994,
mdm2 expression is induced by wild type p53 activity , Barak Y., JUVEN T., HAFFNER R. & Oren M., 2, EMBO Journal, 461-468, 12, 1993, https://doi.org/10.1002/j.1460-2075.1993.tb05678.x
The chicken CdxA homeobox gene and axial positioning during gastrulation , Frumkin A., Haffner R., Shapira E., Tarcic N., Gruenbaum Y. & Fainsod A., 2, Development (Cambridge), 553-562, 118, 1993, https://doi.org/10.1242/dev.118.2.553