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November 01, 2013
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Date:16WednesdayNovember 2022Lecture
The Great Census of Nature And searching the Way to a Sustainable Future
More information Time 19:30 - 21:00Location Michael Sela AuditoriumOrganizer Yad Chaim WeizmannContact -
Date:17ThursdayNovember 2022Lecture
Immunology and Regenerative Biology Colloquium
More information Time 10:00 - 11:00Title H3K9me and heterochromatin in genome stability, chromatin positioning and cell fateLocation Max and Lillian Candiotty BuildingLecturer Prof. Susan M. Gasser
ISREC Foundation and Agora Cancer Research Center, LausanneOrganizer Department of Immunology and Regenerative BiologyContact -
Date:17ThursdayNovember 2022Colloquia
Physics Hybrid Colloquium
More information Time 11:15 - 12:30Title : All known Type Ia supernova models fail to reproduce the observed luminosity-width correlationLocation Edna and K.B. Weissman Building of Physical SciencesLecturer Prof. Doron Kushnir
Weizmann Institute of ScienceOrganizer Faculty of PhysicsContact Abstract Show full text abstract about Type Ia supernovae are fundamental phenomena in nature. They...» Type Ia supernovae are fundamental phenomena in nature. They are one of the leading
distributors of heavy chemical elements and, in some cases, important production sites (e.g., iron). Type Ia supernovae are very homogenous and bright, allowing their distance to be measured on cosmological scales.
In recent years, measurements of Type Ia supernovae have led to the discovery that the universe's expansion is
accelerating, suggesting the existence of dark energy. Type Ia supernovae are likely thermonuclear explosions
of white-dwarf stars, which are sufficiently dense to allow explosive thermonuclear burning if adequately ignited. However, a robust comparison of theoretical scenarios for the progenitor systems to observations is challenging due to the inability to accurately calculate the dynamics of the explosion and the emitted radiation. We have developed novel observational and numerical methods by exploiting the physical principles behind Type Ia supernovae. The new observational techniques allow the derivation of a specific luminosity-width correlation that does not require radiation transfer calculations for comparison. The new numerical methods allow for the first time to calculate this luminosity-width correlation with a percent accuracy for multidimensional
progenitor scenarios with current computational facilities. We show that all known Type Ia supernova models fail to
reproduce the observed luminosity-width correlation.
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Date:17ThursdayNovember 2022Lecture
The ERC-StG project PEOPLE: searching for early Homo sapiens in the interior of South Africa
More information Time 13:30 - 13:30Location Room 590, Benoziyo Building for Biological Science, Weizmann Institute of ScienceLecturer Dr. Michael Toffolo
Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), Burgos, SpainOrganizer Scientific Archeology UnitContact -
Date:17ThursdayNovember 2022Lecture
The ERC-StG project PEOPLE: searching for early Homo sapiens in the interior of South Africa
More information Time 13:30 - 13:30Location Room 590, Benoziyo Building for Biological Science, Weizmann Institute of ScienceLecturer Dr. Michael Toffolo
Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), Burgos, SpainContact -
Date:17ThursdayNovember 2022Lecture
Reprograming T cell immunity to enhance immunotherapy: from protein engineering to bedside
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Cyrille Cohen
Vice-Dean, The Mina and Everard Goodman Faculty of Life Sciences Head, Laboratory of Tumor Immunology and Immunotherapy Bar-Ilan UniversityOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:20SundayNovember 202225FridayNovember 2022Conference
The Physics of Driven Amorphous Materials
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Itamar ProcacciaHomepage -
Date:20SundayNovember 2022Lecture
TBA - M. Magaritz Memorial Lecture: Climate Intervention
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer David Fahey Organizer Department of Earth and Planetary SciencesContact -
Date:20SundayNovember 2022Lecture
Developing gene-based therapies for genetic disorders: A join effort between biotech, academia and patient groups
More information Time 11:00 - 12:00Location Max and Lillian Candiotty BuildingLecturer Dr. Yael Weiss
CEO of Mahzi Therapeutics, San Mateo, California , United StatesOrganizer Department of Immunology and Regenerative BiologyContact -
Date:21MondayNovember 2022Conference
Focus on Cancer Early Detection Research
More information Time 08:00 - 08:00Location Wolfson Building for Biological ResearchChairperson Zvi LivnehHomepage -
Date:21MondayNovember 2022Colloquia
Assembly or disassembly this is the question…
More information Time 11:00 - 12:15Title Annual Pearlman LectureLocation Gerhard M.J. Schmidt Lecture HallLecturer Prof. Luisa De Cola
University of StrasbourgOrganizer Faculty of ChemistryHomepage Contact Abstract Show full text abstract about Molecules that can undergo self-assembly are of great intere...» Molecules that can undergo self-assembly are of great interest for the development of new materials, sensors, biolabels…. In some cases the assembly can lead to an enhancement of the emission, a change in the luminescence energy and even to unexpected biological phenomena.
The talk will illustrate some of the recent results on the self-assembly of platinum complexes and their evolution in solution[1]. Some water soluble compounds where studied to follow the self-assembly even in vivo and the resulting reactivity/toxicity of such species. We employed transparent polyps, Hydra vulgaris and an extraordinary phenomenon was detected with one of the complex that showed a clear effect on pluripotent stem cell proliferation, especially at low doses.
The stabilization of transient species, formed in the assembly process can be achieved using cage type structures can lead to their stabilization or even existence in solution, in a condition out of equilibrium. We recently demonstrated[2] that it is possible to entrap intermediate states of luminescent assemblies and prevent their thermodynamic evolution towards the equilibrium state. Such cages are also the carriers for important drugs do to their destruction inside cells. Their biodistribution is quite unique and they are able to escape macrophages uptake.[3]
References
[1] A. Aliprandi, M. Mauro, L. De Cola Nature Chem., 2016, 8, 10-15
[2] P. Picchetti, G. Moreno-Alcántar, L. Talamini, A. Mourgout, A. Aliprandi, L. De Cola J. Am. Chem. Soc. 2021, 143, 7681-7687.
[3] P. Picchetti et al. ACS Nano 2021, 15, 9701–9716 -
Date:21MondayNovember 2022Lecture
Special Guest Seminar
More information Time 11:00 - 12:00Title "RNA modifications in RNA virus infection: Learning from the experts"Location Max and Lillian Candiotty BuildingLecturer Dr. Inna Ricardo Lax Organizer Department of Immunology and Regenerative BiologyContact -
Date:22TuesdayNovember 2022Lecture
"Dynamic Enhancer Activation and Transcription Factor Interplay Drive the Fasting Response"
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Ido Goldstein
Institute of Biochemistry, Food Science and Nutrition,HUJI Robert H. Smith Faculty of Agriculture, Food and EnvironmentOrganizer Department of Biomolecular SciencesContact -
Date:22TuesdayNovember 2022Lecture
What is the Science behind Climate Change?
More information Time 11:00 - 12:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Peter Rez
Arizona State University Department of PhysicsOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Not a day goes by when we don’t hear about the “climate cris...» Not a day goes by when we don’t hear about the “climate crisis”; some effects are well documented, like the rise in the average global temperature and the shrinking of the polar ice caps. Undoubtedly, carbon dioxide levels in the atmosphere have been increasing, but what does “science” say about the potential consequences? The combination of the atmosphere, oceans, cryosphere and biosphere is the ultimate non-linear coupled complex system. How well do we understand what might happen? In the first part of my talk, I shall review my exploration of the original literature to try and separate out speculation, hypothesis, results of computational models, and most significantly actual observations. In the second part of my talk, I shall discuss what will actually work to reduce carbon dioxide emissions (complete elimination or Net Zero is an impossibility). Although it has become fashionable for governments to impose mandates enshrined in laws, the only laws that matter are the laws of thermodynamics and Ohm’s law. -
Date:22TuesdayNovember 2022Lecture
Environmental viruses in biogeochemical cycles
More information Time 11:30 - 12:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Ella Sieradzki
Ecole Centrale de Lyon- FranceOrganizer Department of Plant and Environmental SciencesContact Abstract Show full text abstract about Viruses are the most abundant and diverse biological entitie...» Viruses are the most abundant and diverse biological entities on Earth and can have a profound effect on biogeochemical cycles. In the sunlit ocean, viral lysis of 20-40% of hosts daily generates 20% of the dissolved organic carbon pool. Viruses can also affect their host’s metabolism during infection through expression of horizontally transferred host metabolic genes. While viruses in the ocean have been studied for over two decades, viral ecology and its effects have been neglected in other environments. I will present several of my studies that show how viruses in the ocean and in soil may affect their environment as well as ours through expression of metabolic genes and host-specific mortality. I’ll also discuss the current limitations in soil viral ecology, and technologies that can help us move forward. -
Date:22TuesdayNovember 2022Lecture
Molecular maps for odor processing in the mouse olfactory system
More information Time 12:30 - 13:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Alexander Fleischmann
Brown University, Providence, USAOrganizer Department of Brain SciencesContact Abstract Show full text abstract about We are interested in the organization and function of neural...» We are interested in the organization and function of neural circuits for sensory processing and behavior. A main goal of the lab is to integrate complementary approaches of system interrogation: we study the molecular diversity of cell types, their connectivity and functional properties; we investigate network dynamics and core computational principles; and we explore how learning and experience shapes behavioral decisions.
I will discuss ongoing work aimed at characterizing molecular maps for odor processing in the mouse olfactory bulb. I will present preliminary data using spatial transcriptomics to generate a comprehensive map of glomerular identity and domain structure of the olfactory bulb. Furthermore, I will discuss single cell sequencing experiments and gene regulatory network models that define the diversity and connectivity of olfactory bulb projection neurons.
I will try to illustrate how the early olfactory system of mice provides an ideal model system to integrate molecular biology, functional imaging, and behavioral experiments to address fundamental questions in sensory processing and behavior.
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Date:22TuesdayNovember 2022Lecture
Mechanism of virus capsid assembly and disassembly
More information Time 14:00 - 15:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Uri Raviv
Institute of Chemistry The Hebrew University of JerusalemOrganizer Department of Chemical and Structural BiologyContact -
Date:23WednesdayNovember 2022Lecture
The Role of Active Encapsulation in Perovskite Solar Cells
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Prof. Shaibal Sarkar
at Department of Energy Science and Engineering, IIT BombayOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about From a perovskite photovoltaic device standpoint, the Al2O3 ...» From a perovskite photovoltaic device standpoint, the Al2O3 ALD can be thought of as a thin film encapsulate to protect the underlined material from the extrinsic entities. However, as per the literature is concerned, the role of Al2O3 ALD in the perovskite photovoltaic devices is much beyond a mare passive component. This raises a severe ambiguity over the choice of surface (or interface) on which ALD needs to be done for optimized device performance, in terms of the device efficiency and stability.
In my presentation, I would like to elucidate the characteristic differences between the surface limited and substrate enhanced ALD processes which is important to perovskite devices. The objective here is to discuss a unified correlation between the role of the Al2O3 ALD mechanism with the perovskite device performance by excluding popular overestimated assumption about the conformality on non-ideal surface, like perovskite or organic thin films. In addition, I would like to emphasize on the fact that how the ALD process can be used to passivate the buried interfacial defect and enhancing the VOC, PL and ELQE.
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Date:24ThursdayNovember 2022Lecture
Special Guest Seminar
More information Time 10:00 - 10:00Title "Autophagy - from cargo to structure"Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Florian Wilfling Organizer Department of Molecular GeneticsContact -
Date:24ThursdayNovember 2022Lecture
M.Sc thesis defense: "Self-Integrating Memories Based on Guided Nanowires"
More information Time 11:00 - 12:00Location Helen and Milton A. Kimmelman BuildingLecturer Omri Ron
M.Sc student in Prof. Ernesto Joselevich's groupOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Neuromorphic computing designs have an important role in the...» Neuromorphic computing designs have an important role in the modern ‘big data’ era, as they are suitable for processing large amount of information in short time, eliminating the von Neumann (VN) bottleneck. The neuromorphic hardware, taking its inspiration from the human brain, is designed to be used for artificial intelligence tasks via physical neural networks, such as speech or image recognition, bioinformatics, visual art processing and much more. The memristor (memory + resistor), is one of the promising building blocks for this hardware, as it mimics the behavior of a human synapse, and can be used as an analog non-volatile memory. The memristor has been proven as a viable memory element and has been used for constructing resistive random access memory (RRAM) as a replacement for current VN hardware. However, the mechanism of operation and the conducting bridge formation mechanisms in electrochemical metallization memristors still require further investigation. A planar single-nanowire (NW) based memristor is a good solution for elucidating the mechanism of operation, thanks to the high localization of switching events, allowing in-situ investigation as well as post-process analysis. Our group, which has developed the guided-growth approach to grow guided planar NWs on different substrates, has used this method to integrate guided epitaxial NWs into functional devices such as field-effect transistors (FETs), photodetectors and even address decoders. However, the guided-growth approach has not been used for creating memristors up to date.
In this work, I successfully synthesized guided NWs of two metal-oxides on flat and faceted sapphire substrates – ZnO and β-Ga2O3 were successfully grown in the VLS mechanism as surface guided NWs. I successfully grew planar guided β-Ga2O3 NWs on six different sapphire substrates, for the first time as far as we know. We characterized the newly grown β-Ga2O3 NWs with SEM, TEM, EDS and Raman spectroscopy. The monoclinic NWs grew along surprising directions on the flat sapphire surfaces and I demonstrated a new mode of growth – epitaxy favored growth on a faceted surface, when graphoepitaxy is also possible. I created electrochemical metallization memristors with the obtained NWs and successfully demonstrated the effect of resistive switching for β-Ga2O3 guided NW based devices. With the abovementioned achievements, we expanded the guided-growth approach on flat and faceted sapphire surfaces, and opened the opportunity for creating surface guided-NW based neuromorphic hardware.