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  • Date:25SundayOctober 2020

    Department seminar with Batsheva Rozman

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    Time
    13:00 - 14:00
    Title
    “Temporal dynamics of HCMV gene expression in lytic and latent infection”
    Lecturer
    Batsheva Rozman
    Organizer
    Department of Molecular Genetics
    Student and Post-Doc Seminar
    Contact
    Lecture
  • Date:25SundayOctober 2020

    Mechanisms of β-cell functional adaptation to changes in nutrition

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    Time
    15:00 - 16:00
    Lecturer
    Dr. Ronny Helman
    Institute of Biochemistry, Food Science and Nutrition, The Robert H Smith Faculty of Agriculture, Food and Environment HUJI, Israel
    Organizer
    Life Sciences
    Metabollic Research Forum
    Contact
    Lecture
  • Date:26MondayOctober 202029ThursdayOctober 2020

    16th Transgenic Technology Meeting

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    Time
    08:00 - 08:00
    Location
    Michael Sela Adutitorium
    Chairperson
    Rebecca Haffner-Krausz
    Contact
    Conference
  • Date:26MondayOctober 2020

    Online Israel Physics Colloquium: "The magic of moiré quantum matter"

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    Time
    16:00 - 17:15
    Location
    https://weizmann.zoom.us/j/93903178346?pwd=VUJNa0Z1NkZhZDhjTnRXeVVGbEszUT09
    Lecturer
    Pablo Jarillo-Herrero
    MIT, USA
    Organizer
    Faculty of Physics
    Homepage
    Contact
    AbstractShow full text abstract about The understanding of strongly-correlated quantum matter has ...»
    The understanding of strongly-correlated quantum matter has challenged physicists for decades.
    Such difficulties have stimulated new research paradigms, such as ultra-cold atom lattices for
    simulating quantum materials. In this talk I will present a new platform to investigate strongly correlated physics, namely moiré quantum matter. In particular, I will show that when two graphene sheets are twisted by an angle close to the theoretically predicted ‘magic angle’, the resulting flat band structure near the Dirac point gives rise to a strongly-correlated electronic system. These flat bands systems exhibit a plethora of quantum phases, such as correlated
    insulators, superconductivity, magnetism, Chern insulators, and more. Furthermore, it is possible to extend the moiré quantum matter paradigm to systems beyond magic angle graphene, and I will present an outlook of some exciting directions in this emerging field.
    Colloquia
  • Date:27TuesdayOctober 2020

    Protein evolution – from so simple a beginning

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Cafeteria
    Lecturer
    Prof. Dan Tawfik
    Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    DetailsShow full text description of Via Zoom: https://weizmann.zoom.us/j/93358772888?pwd=Z1ZIe...»
    Via Zoom:
    https://weizmann.zoom.us/j/93358772888?pwd=Z1ZIeWs3N
    Lecture
  • Date:28WednesdayOctober 2020

    Algebraic Geometry and Representation Theory Seminar

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    Time
    16:30 - 18:00
    Title
    Bessel-Fourier coefficients and Twisted Automorphic Descent
    Lecturer
    Lei Zhang
    National University of Singapore
    Organizer
    Faculty of Mathematics and Computer Science
    Faculty of Mathematical Sciences Seminar
    Contact
    DetailsShow full text description of In this talk, we will discuss the theory of twisted automorp...»
    In this talk, we will discuss the theory of twisted automorphic descents, which is an extension of the automorphic descent of Ginzburg-Rallis-Soudry.

    The main goal is to construct cuspidate automorphic modules in the generic global Arthur packets by using Bessel-Fourier coefficients of automorphic representations.

    Moreover, we will discuss some applications and problems related Bessel-Fourier coefficients.

    This is a joint work with Dihua Jiang.

    Lecture
  • Date:29ThursdayOctober 2020

    BRCA mutations rewire stromal cells in the tumor microenvironment

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Dr Ruth Scherz-Shouval
    Dept. of Biomolecular Sciences Weizmann Institute of Science
    Organizer
    Dwek Institute for Cancer Therapy Research
    Cancer Research Club
    Contact
    DetailsShow full text description of https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2...»
    https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09
    Lecture
  • Date:01SundayNovember 202004WednesdayNovember 2020

    Extracellular vesicles friends and foes II

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Chairperson
    Neta Regev-Rudzki
    Contact
    Conference
  • Date:03TuesdayNovember 2020

    Order from Chaos: Chromosome Catastrophes Drive Cancer Evolution

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Lecturer
    Dr. Ofer Shoshani
    Department of Cellular and Molecular Medicine, University of California, San Diego
    Organizer
    Department of Biomolecular Sciences
    Contact
    DetailsShow full text description of Via Zoom:...»
    Via Zoom:
    AbstractShow full text abstract about Chromosomal instability is one of the major hallmarks in can...»
    Chromosomal instability is one of the major hallmarks in cancer driving numerical and structural chromosome aberrations. Cancer cells can use the chaotic background of chromosome instability to generate ordered genomic events leading to accelerated tumor formation or drug resistance. First, I will discuss how transient centrosome amplification can induce a burst of chromosomal instability in vivo. This triggers the formation of random aneuploidies (changes in chromosome numbers) with cancer initiating cells carrying a specific aneuploidy signature leading to accelerated tumorigenesis. This work has uncovered aneuploidy as a direct driver of cancer and enables a better understanding of the involvement of specific aneuploidies in cancer. Second, I will describe how chromothripsis, the catastrophic shattering of a chromosome and random religation of its pieces, can promote resistance to therapy. Using cancer cells and patient samples, I identified that chromothripsis drives the formation and evolution of extrachromosomal DNA (ecDNA) elements that can amplify genes conferring drug resistance. Chromothripsis depends on non-homologous DNA end joining repair, a vulnerability that could be exploited for therapeutic purposes by preventing resistance to chemotherapy. I will conclude by discussing an outlook towards the exciting new directions opened by this work.

    Lecture
  • Date:03TuesdayNovember 2020

    Immune therapy for Alzheimer’s disease and Dementia: From the bench to the bedside

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    Time
    12:30
    Lecturer
    Prof. Michal Schwartz
    Department of Neurobiology, WIS
    Organizer
    Department of Neurobiology
    Contact
    DetailsShow full text description of Seminar on Zoom https://weizmann.zoom.us/j/93371812582?pwd=...»
    Seminar on Zoom
    https://weizmann.zoom.us/j/93371812582?pwd=VEpIZHB1U0QwMWNhY05FWWtZcVZnQT09

    Meeting ID: 933 7181 2582
    Password: 610265
    AbstractShow full text abstract about With increased life expectancy, the incidence of patients su...»
    With increased life expectancy, the incidence of patients suffering from Alzheimer’s disease (AD) and dementia has been steadily increasing. Currently, there is not a single treatment that can change the diseases course. Our team, over more than two decades, has demonstrated that the brain needs support from the immune system for its life-long functional plasticity and repair. Furthermore, using immunological and immunogenomic tools, we demonstrated that in AD, the immune system dysfunctions and perpetuates the pathology. Based on these observations and numerous others, we proposed that boosting the systemic immune system might facilitate mobilization of immune cells to help the brain. We found that the optimal way to activate such a reparative immune response is by reducing the restraints on the immune system, by blocking the PD-1/PD-L1 inhibitory immune checkpoint pathway. This therapy facilitates translocation of phagocytic cells to the brain; based on their transcriptomic profile, we demonstrated that these cells express molecules that can uniquely remove the toxic forms of misfolded proteins plaques, dead cells, and cell debris, and can thereby rescue synapses, change the disease course and improve brain function. Overall, our results indicate that targeting systemic and local immune cells rather than brain-specific disease-escalating factors provides a multi-dimensional disease-modifying therapy for AD and dementia, regardless of the primary disease etiology. Our approach is under an expedited development process towards clinical trial.

    Lecture
  • Date:05ThursdayNovember 2020

    Production and function of EVs in infectious disease

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Neta Regev-Rudzki
    Contact
    Conference
  • Date:05ThursdayNovember 2020

    Production and function of EVs in infectious disease

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Neta Regev-Rudzki
    Organizer
    The Dimitris N. Chorafas Institute for Scientific Exchange
    Contact
    Conference
  • Date:05ThursdayNovember 2020

    TBA

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    Time
    11:15 - 12:30
    Location
    https://weizmann.zoom.us/j/92790893230?pwd=VlRjVzkvaGZ5YWRvcXFGWXVXZ3dXdz09
    Lecturer
    Efi Efrati
    WIS
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about TBA ...»
    TBA
    Colloquia
  • Date:05ThursdayNovember 2020

    RNA centered molecular mechanisms of carcinogenesis

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Prof. Gideon Rechavi
    Sheba Cancer Research Center and Tel Aviv University
    Organizer
    Department of Biological Regulation
    Cancer Research Club
    Contact
    DetailsShow full text description of https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2...»
    https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09
    Lecture
  • Date:08SundayNovember 202012ThursdayNovember 2020

    SAAC Meeting 2020

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    Time
    All day
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Contact
    International Board
  • Date:10TuesdayNovember 2020

    To be announced

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Cafeteria
    Lecturer
    Prof. Zvi Livneh
    Dept. of Biomolecular Sciences - WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    DetailsShow full text description of Via Zoom:...»
    Via Zoom:
    Lecture
  • Date:15SundayNovember 202018WednesdayNovember 2020

    The 72nd Annual Meeting of the International Board 2020

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    Time
    All day
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Contact
    International Board
  • Date:17TuesdayNovember 2020

    To be announced

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Cafeteria
    Lecturer
    Dr. Leeat Keren
    Dept. of Molecular Cell Biology - WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture
  • Date:19ThursdayNovember 2020

    TBA

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    Time
    11:15 - 12:30
    Location
    https://weizmann.zoom.us/j/92790893230?pwd=VlRjVzkvaGZ5YWRvcXFGWXVXZ3dXdz09
    Lecturer
    Ofer Firstenberg
    WIS
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about TBA ...»
    TBA
    Colloquia
  • Date:19ThursdayNovember 2020

    Cancer evolution, immune evasion and metastasis

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Prof. Charles Swanton MD PhD FMedSci FRS
    Francis Crick Institute & UCL Cancer Institute, London, UK.
    Organizer
    Dwek Institute for Cancer Therapy Research
    Cancer Research Club
    Contact
    DetailsShow full text description of https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2...»
    https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09
    Lecture

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