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  • Date:20MondayNovember 2017

    Bridging between personalized medicine and T-cell based immunotherapy

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    Time
    14:00 - 15:00
    Title
    Special Guest Seminar
    Location
    Max and Lillian Candiotty Building
    Auditorium
    Lecturer
    Prof. Cyrille Cohen
    Head, Laboratory of Tumor Immunology and Immunotherapy, Head, Division of Human and Medical Biology, Faculty of Life Sciences, Bar-Ilan University
    Organizer
    Department of Biological Regulation
    Contact
    Lecture
  • Date:20MondayNovember 2017

    From strong passivity to extended second law of thermodynamics and new thermodynamic predictions on quantum microscopic systems

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    Time
    14:15
    Lecturer
    Ram Uzdin, Technion
    Organizer
    Department of Physics of Complex Systems
    Contact
    AbstractShow full text abstract about To thermodynamically address quantum nanoscopic scenarios th...»
    To thermodynamically address quantum nanoscopic scenarios that involve very small heat sources and strong system-bath correlation, we suggest a new framework that is based on the principle of passivity. Passivity allows to get many thermodynamic inequalities that constrain observables that were so far outside the scope of thermodynamics. As an example we derive lower and upper bounds on the system-bath energy covariance in the Jaynes-Cummings model (spin-oscillator interaction). Using a stronger version of the passivity principle, we extend the second law to handle initial system-bath correlation (which is common in microscopic strong system-bath coupling scenarios). In addition, it is shown that passivity-based inequalities can detect "sub-Maxwellian” demons that apply a feedback that is too subtle to be detected using the standard second law. Finally an intrinsically quantum feature of strong passivity is exploited to assign a thermodynamic cost for quantum coherence generation.

    Lecture
  • Date:21TuesdayNovember 2017

    "Coordination of microbial metabolism through metabolite-protein interactions”

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    Time
    10:00 - 11:00
    Title
    Systems in Frontiers Seminar
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Prof. Uwe Sauer
    Institute of Molecular Systems Biology, ETH Zurich
    Organizer
    The Azrieli Institute for Systems Biology
    Contact
    Lecture
  • Date:21TuesdayNovember 2017

    Assembly, structure, and function of a bacterial nanosyringe

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Prof. Samuel Wagner
    Institute for Microbiology and Infection Medicine University of Tübingen
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture
  • Date:21TuesdayNovember 2017

    Redox-Active Alkenylruthenium Complexes and Metallamacrocycles: Charge, Spin and Polyelectrochromism

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    Time
    11:00 - 12:30
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. Dr. Rainer F. Winter
    University Konstanz
    Organizer
    Department of Organic Chemistry
    Contact
    Lecture
  • Date:21TuesdayNovember 2017

    Algebraic Geometry and Representation Theory Seminar

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    Time
    11:15 - 12:30
    Title
    Uniform p-adic integration and applications
    Location
    Jacob Ziskind Building
    Room 290C
    Lecturer
    Raf Cluckers
    University of Lille
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    Lecture
  • Date:21TuesdayNovember 2017

    Antimalarial herbicides and herbicidal antimalarials: exploiting the plant-Plasmodium connection

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    Time
    11:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Dr. Joshua S. Mylne
    School of Molecular Sciences, University of Western Australia, Crawley, Australia, www.mylne.org
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    AbstractShow full text abstract about Plants and apicomplexan parasites are more closely related...»

    Plants and apicomplexan parasites are more closely related than many might expect. Both evolved from a red algal ancestor and both still possess plastids. Plants have chloroplasts whereas apicomplexans like the malarial parasite Plasmodium falciparum have an apicoplast. This diminished ‘relic’ plastid is no longer photosynthetic, but remains essential for its production of isoprenoid precursors. Proof the apicoplast was of plant origin was provided, in part, by killing P. falciparum with herbicides. We recently turned this idea on its head asking whether drugs designed to treat malaria might be herbicidal and found many indeed were [1]. This has led us to apply the rapid advances in malaria research over the last decade to the stagnant field of herbicide discovery [2-3]. The success of glyphosate and spiralling cost of bringing new compounds to market stopped discovery programs by agrochemical companies and consequently, no new herbicide mode of action has reach the market in 20 years. Herbicide resistance has the world in a panic. Using antimalarial drug libraries and knowledge of malarial drug action we are attempting to put as many new modes of action ‘on the table’ as we can, each accompanied by an herbicidal molecule to probe each target [4]. A by-product of this applied work has already been knowledge about what, in many cases, are under-studied plant proteins [4].

    [1] Corral, Leroux, Stubbs, Mylne (2017) Herbicidal properties of antimalarial drugs. Scientific Reports (PMID 28361906).
    [2] Gandy, Corral, Mylne*, Stubbs* (2015) An interactive database to explore herbicide physicochemical properties. Org. Biomol. Chem. (PMID 25895669)
    [3] Corral, Leroux, Tresch, Newton, Stubbs*, Mylne* (2017) Exploiting the evolutionary relationship between malarial parasites and plants to develop new herbicides. Angew. Chem. Int. Ed. Engl. (PMID 28654179)
    [4] Various et al. (under review or in prep.) ... you have to come to find out more!
    Lecture
  • Date:21TuesdayNovember 2017

    "The single-molecule conformational dynamics an ABC transporter"

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    Time
    14:00 - 15:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. Oded Lewinson
    Technion
    Organizer
    Department of Structural Biology
    Contact
    Lecture
  • Date:21TuesdayNovember 2017

    Joint Chemical and Biological Physics and Organic Chemistry Seminar

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    Time
    14:00
    Title
    Molecular water oxidation catalysts anchored on solid surfaces
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Antoni Llobet
    Institute of Chemical Research of Catalonia (ICIQ), Institute of Science and Technology, Tarragona and Department de Química Universitat Autònoma de Barcelona
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about The replacement of fossil fuels by a clean and renewable ene...»
    The replacement of fossil fuels by a clean and renewable energy source is one of the most urgent and challenging issues our society is facing today, which is why intense research is devoted to this topic recently. Nature has been using sunlight as the primary energy input to oxidize water and generate carbohydrates (a solar fuel) for over a billion years. Inspired, but not constrained, by nature, artificial systems [1] can be designed to capture light and oxidize water and reduce protons or other organic compounds to generate useful chemical fuels. In this context this contribution will present a variety of molecular water oxidation catalysts based on transition metal complexes, together with their activity in homogeneous phase and anchored on solid surfaces to generate electro- and photo-anodes. A detailed analysis of their performance will be discussed.
    Lecture
  • Date:22WednesdayNovember 2017

    When enhancers drive the wrong genes: Mechanisms and role in tumorigenesis

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    Time
    09:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Dr. Yotam Drier
    Massachusetts General Hospital and Broad Institute
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:22WednesdayNovember 2017

    Chemical and Biological Physics Dept Guest Seminar

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    Time
    10:00
    Title
    Actin flows in cell migration: from locomotion to trajectories
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof Raphael Voituriez
    CNRS, Paris
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about Eukaryotic cell movement is characterized by very diverse mi...»
    Eukaryotic cell movement is characterized by very diverse migration modes. Recent studies show that cells can adapt to environmental cues, such as adhesion and geometric confinement, thereby readily switching their mode of migration. Among this diversity of motile behaviors, actin flows have emerged as a highly conserved feature. Based on active gel models of cytoskeleton dynamics, I will argue that the various observed migration modes are continuous variations of elementary locomotion mechanisms, which rely on a very robust physical property of the actin/myosin system: its ability to sustain flows at the cell scale. This central role of actin/myosin flows will be shown to affect the large scale properties of cell trajectories.
    Lecture
  • Date:22WednesdayNovember 2017

    Microwave and terahertz response of carbon nanotube based media”

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    Time
    11:00 - 12:00
    Location
    Perlman Chemical Sciences Building
    Room 404
    Lecturer
    Dr. M. V. Shuba
    Institute for Nuclear Problems, Belarus State University, Minsk
    Organizer
    Department of Materials and Interfaces
    Contact
    DetailsShow full text description of Intensive investigation of the electromagnetic properties ...»

    Intensive investigation of the electromagnetic properties of carbon nanotubes (CNTs) is stimulated by the combination of unique electronic properties and the high aspect ratio of these nanoparticles. Nowadays CNTs are considered as prospective candidates for different electromagnetic devices such as interconnects, transmission lines, and nanoantennas.
    We present the results of a systematical theoretical analysis and experimental study of the electromagnetic and optical properties of single- and multi-walled CNTs. Analysis has been done in a broad frequency range from radiofrequency up to ultraviolet. Many interesting effects in finite-length CNTs will be presented, including: propagation of slowed-down surface waves, localized plasmon (antenna) resonance in the terahertz range, screening effect in microwave and radio-frequency ranges, strong near-field enhancement effect. Potential of the CNT application as building blocks for the fabrication of high dielectric constant materials in the terahertz range is shown. The advantages of CNT/WS2 nanotube hybrid films over other CNT based composites are discussed.
    Lecture
  • Date:22WednesdayNovember 2017

    Algebraic Geometry and Representation Theory Seminar

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    Time
    11:15 - 12:30
    Title
    About Index of Lie Algebras
    Location
    Jacob Ziskind Building
    Room 290C
    Lecturer
    Alexander Elashvili
    Razmadze Mathematical Institute
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    AbstractShow full text abstract about In my talk I plan to give overview of results about of index...»
    In my talk I plan to give overview of results about of index of biparaboic subalgebras of classical Lie algebras and
    formulate conjecture about asymptotic biheviar of lieandric numbers.
    Lecture
  • Date:22WednesdayNovember 2017

    Teaching how to learn in school science:research & development

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    Time
    12:00 - 13:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Dr. Zahava Scherz
    Dean for Educational Activities
    Contact
    Lecture
  • Date:22WednesdayNovember 2017

    Special Guest Lecture

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    Time
    16:15 - 18:00
    Title
    The pressure function for infinite equilibrium
    Location
    Jacob Ziskind Building
    Room 290C
    Lecturer
    Dalia Terhesiu
    Exeter University
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    Lecture
  • Date:22WednesdayNovember 2017

    Special Guest Lecture

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    Time
    16:15 - 18:00
    Title
    The pressure function for infinite equilibrium
    Location
    Jacob Ziskind Building
    Room 290C
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    Lecture
  • Date:23ThursdayNovember 2017

    Systems Chemistry, Dynamic Chemical Networks, Macromolecular Function, and Alternative Chemistries of Life

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    Time
    11:00 - 12:30
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. David Lynn
    Emory University
    Organizer
    Department of Organic Chemistry
    Contact
    Lecture
  • Date:23ThursdayNovember 2017

    The past of a quantum particle

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Lecturer
    Lev Vaidman
    TAU
    Organizer
    Faculty of Physics
    Contact
    DetailsShow full text description of 11:00 Coffee, Tea and more ...»
    11:00 Coffee, Tea and more
    AbstractShow full text abstract about Textbooks of quantum mechanics lack the concept of the past ...»
    Textbooks of quantum mechanics lack the concept of the past of quantum systems. Few years ago I proposed to define the past of a quantum particle according the trace it leaves. While in many cases this definition provides a reasonable description, for a nested Mach-Zehnder interferometer it leads to a picture seemingly contradicting common sense: the particle leaves a trace in a place through which it could not pass. I will discuss recent theoretical and experimental studies of this controversial issue.
    Colloquia
  • Date:23ThursdayNovember 2017

    Vision and Robotics Seminar

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    Time
    12:15 - 13:30
    Title
    Seeing Through Noise: Visually Driven Speaker Separation and Enhancement
    Location
    Jacob Ziskind Building
    Room 1
    Lecturer
    Aviv Gabbay
    Hebrew University
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    Lecture
  • Date:23ThursdayNovember 2017

    Geometric Functional Analysis and Probability Seminar

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    Time
    14:10 - 16:00
    Title
    Persistence of Gaussian Stationary Processes
    Location
    Jacob Ziskind Building
    Room 290C
    Lecturer
    Naomi Feldheim
    WIS
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    Lecture

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