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Date:25TuesdayMarch 2025Lecture
Molecular Origami and the Hidden Rules of Protein Complex Evolution
More information Time 14:00 - 15:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Saurav Malik Organizer Department of Chemical and Structural Biology -
Date:27ThursdayMarch 2025Lecture
Geometric Functional Analysis and Probability Seminar
More information Time 11:00 - 12:00Title Boundaries of attractors of diffeomorphisms subject to a bounded diffusive noiseLocation Jacob Ziskind Building
Room 1 - 1 חדרLecturer Dmitry Turaev
Imperial CollegeOrganizer Department of MathematicsContact Abstract Show full text abstract about We show that the unit normal bundle of a smooth boundary of ...» We show that the unit normal bundle of a smooth boundary of an attractor for random dynamical systems of a certain natural class is a Legendrian invariant manifold of a deterministic map which preserves a contact structure. In this framework, random dynamics can be described and analyzed by purely deterministic means. -
Date:27ThursdayMarch 2025Colloquia
Simulating high-temperature superconductivity in a triangular moiré lattice
More information Time 11:15 - 12:15Location Physics Weissman AuditoriumLecturer Prof. Kin Fai Mak
Light refreshments at 11:00Organizer Department of Condensed Matter PhysicsAbstract Show full text abstract about <p>Moiré materials built on transition metal dichalcog...» <p>Moiré materials built on transition metal dichalcogenide semiconductors have emerged as a tunable platform for simulating the Hubbard model on a triangular lattice. A natural question arises: Can the platform be tuned to yield a phase diagram similar to that in high-temperature cuprate superconductors? In this talk, I will discuss the emergence of “high-temperature” superconductivity near the Mott transition in a triangular moiré lattice with intermediate coupling strength. The emergent doping-temperature phase diagram looks remarkably similar to that in cuprate superconductors. I will also discuss the evolution of the phase diagram by tuning the band structure of the material by gating. The results could provide a new angle for understanding the phenomenon of high-temperature superconductivity in strongly correlated materials. </p><p> </p> -
Date:27ThursdayMarch 2025Lecture
Regulation of immune cell function in tumor microenvironment of triple-negative breast cancer
More information Time 14:00 - 15:00Location Max and Lillian Candiotty Building
AuditoriumLecturer Prof. Idit Shachar Organizer Dwek Institute for Cancer Therapy Research -
Date:27ThursdayMarch 2025Lecture
Metabolism, Clonality and Immunotherapy: A Single-Cell PerspectiveTo be announced
More information Time 15:00 - 16:00Location Nella and Leon Benoziyo Building for Biological Sciences
Auditorium Rm. 191Lecturer Dr. Keren Yizhak
Faculty of Medicine, Technion - Israel Institute of Technology, HaifaAbstract Show full text abstract about <p>Understanding why some patients respond to immune c...» <p>Understanding why some patients respond to immune checkpoint therapy while others do not remains a critical challenge in cancer research. This talk will explore three key studies that shed light on this question. First, we uncover metabolic predictors of response to checkpoint blockade therapy, revealing how tumor and immune cell metabolism shape treatment outcomes. Next, we present a single-cell meta-analysis of T cell clonal dynamics, highlighting their role in immunotherapy success. Finally, we introduce scXpand, a machine-learning approach for predicting T cell clonality from scRNA-seq, offering a novel tool to enhance immunotherapy research and precision medicine.</p> -
Date:27ThursdayMarch 2025Academic Events
PhD defense- Eliran offer
More information Time 15:00 - 17:00Title Viral and bacterial synergy in pathogenicity expedites algal bloom demiseLocation Nella and Leon Benoziyo Building for Plant and Environmental Sciences
690Lecturer Eliran Soffer Contact -
Date:27ThursdayMarch 2025Lecture
Vision and AI
More information Time 16:30 - 17:30Title Decomposing Images through Compositional Energy FunctionsLecturer Yilun Du
Google Deepmind, HarvardOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about Given a distribution of images, how can we can decompose the...» Given a distribution of images, how can we can decompose the data into a set of underlying components? In this talk, I'll present an approach that decomposes images into a underlying composable energy functions. I'll illustrate how energy functions allow us to represent both global components of an image, such as lighting as well as local components such as objects. I'll further show how we leverage pretrained vision models to infer these components. Finally, I'll illustrate how discover components can be recombined to form a variety of images substantially different than those seen at training time.
Speaker's bio:
Yilun Du is an incoming assistant professor at Harvard and is currently a senior research scientist at Google Deepmind. He received has PhD and BS from MIT and was supported by a NSF graduate fellowship. -
Date:27ThursdayMarch 2025Cultural Events
Rona Kenan at Sela
More information Time 21:00 - 22:30Location Michael Sela AuditoriumContact -
Date:29SaturdayMarch 2025Cultural Events
A Visitor for Bear | Mediatheque Theater
More information Time 11:00 - 12:00Location Michael Sela AuditoriumHomepage Contact -
Date:30SundayMarch 2025Lecture
Special Guest Seminar - Dr. Thierry Nordmann
More information Time 11:15 - 12:15Title Unraveling the Molecular Architecture of the Skin for Personalized MedicineLocation Wolfson AuditoriumLecturer Dr. Thierry Nordmann Organizer Department of Molecular Cell BiologyContact -
Date:30SundayMarch 2025Lecture
The Clore Center for Biological Physics
More information Time 12:45 - 14:30Title An information content principle explains regulatory patterns of human gene expression across tissues.Location Nella and Leon Benoziyo Physics LibraryLecturer Professor Yitzhak Pilpel
Lunch at 12:45Contact Abstract Show full text abstract about <p>In my talk I will introduce a novel framework that ...» <p>In my talk I will introduce a novel framework that applies a principle from information theory, that of Minimum Description Length (MDL), to understand how regulation of human gene expression across organs, tissues is shaped by regulatory architecture.</p><p>Examination of expression patterns of human genes across the body reveals an intriguing duality: While many genes are expressed in only one tissue, others, known as “housekeeping genes”, are ubiquitously expressed in essentially every tissue. Yet, interestingly, a considerable portion of the genes are on the mid-range, deliberately expressed in many tissues but are also absent in many others.</p><p>Intuitively, in human language terms, specifying the expression program of the genes on the two ends of the spectrum requires a short description – e.g. “expressed in all tissues”, or “expressed only in brain”. Yet specifying the expression of genes in the middle of the scale requires longer description, or a longer MDL, having to specify in each tissue if the gene is expressed or not, and at what level. We sought to measure regulatory complexity of each human gene and examine if the MDL principle predicts and explains regulatory complexity. Our findings lend support to the MDL principle’s prediction. Our measure of regulatory complexity of a gene’s expression pattern can be predicted by quantifying its regulatory information content. In the talk we shall discuss evolutionary implications to the development of multi-cellularity.</p><p><strong>FOR THE LATEST UPDATES AND CONTENT ON SOFT MATTER AND BIOLOGICAL PHYSICS AT THE WEIZMANN, VISIT OUR WEBSITE: https://www.biosoftweizmann.com/</strong></p><p> </p> -
Date:30SundayMarch 2025Lecture
It’s an Emergency: What It Means to Be a Scientist in an Era of Climate and Ecological Breakdown
More information Time 13:00 - 14:00Title IES- Institute For Environmental Sustainability Initiative seminar series 2025-2026Location Nella and Leon Benoziyo Building for Plant and Environmental Sciences
690Lecturer Dr. Avner Gross Organizer The Institute for Environmental Sustainability -
Date:31MondayMarch 2025Academic Events
Scientific Council Meeting
More information Time 10:00 - 12:00Location The David Lopatie Conference Centre
KIMELContact -
Date:31MondayMarch 2025Colloquia
Decoding the molecular mechanism of histone modification
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Cynthia Wolberger
Department of Biophysics and Biophysical Chemistry, The Johns Hopkins UniversityOrganizer Department of Chemical and Structural BiologyHomepage Contact Abstract Show full text abstract about <p>Post-translational modifications of histones play a...» <p>Post-translational modifications of histones play a central role in regulating all cellular processes requiring access to DNA. Monoubiquitinated histone H2B-K120 is a hallmark of actively transcribed genes that plays multiple roles in activating transcription, while monoubiquitinated histone H2A-K119 is abundant in heterochromatin, which is transcriptionally silent. Our structural studies have revealed how histone H2B is specifically ubiquitinated and deubiquitinated, and ubiquitinated H2B stimulates histone methylation. We have also shown how ubiquitin can regulate access to the nucleosome acidic patch, a hotspot for interactions with other chromatin-modifying enzymes. I will also discuss recent studies of a histone kinase that has an unusual mode of binding nucleosomes.</p> -
Date:01TuesdayApril 2025Lecture
Confident modeling and manipulation of unconfident interactions
More information Time 14:00 - 15:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Ora Furman Organizer Department of Chemical and Structural Biology -
Date:01TuesdayApril 2025Cultural Events
Sela Jazz Bar #4 From East to West I Turkiz Ensemble
More information Time 21:00 - 22:15Location Michael Sela AuditoriumHomepage Contact -
Date:02WednesdayApril 2025Lecture
students seminar series- Azrieli
More information Time 10:30 - 12:30Location Camelia Botnar BuildingContact -
Date:02WednesdayApril 2025Lecture
Life Sciences Luncheon
More information Time 12:30 - 14:00Title Prof. Ziv ShulmanLocation Nella and Leon Benoziyo Building for Biological Sciences
AuditoriumLecturer Prof. Ziv Shulman
Antibody evolution in cancerContact -
Date:03ThursdayApril 2025Cultural Events
אירוע התנדבות מכוני
More information Time 09:00 - 13:00Location מחוץ למכוןContact -
Date:03ThursdayApril 2025Lecture
Bioinformatics Unit at LSCF: Recent highlights, Single-Cell Insights, and AI Solutions for bioimaging
More information Time 09:00 - 10:00Location Candiotty AuditoriumLecturer Dr. Dena Leshkowitz, Dr. Ido Azuri Organizer Department of Life Sciences Core Facilities