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  • Date:25TuesdayMarch 2025

    Molecular Origami and the Hidden Rules of Protein Complex Evolution

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    Time
    14:00 - 15:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerDr. Saurav Malik
    Organizer
    Department of Chemical and Structural Biology
    Lecture
  • Date:27ThursdayMarch 2025

    Geometric Functional Analysis and Probability Seminar

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    Time
    11:00 - 12:00
    Title
    Boundaries of attractors of diffeomorphisms subject to a bounded diffusive noise
    Location
    Jacob Ziskind Building
    Room 1 - 1 חדר
    LecturerDmitry Turaev
    Imperial College
    Organizer
    Department of Mathematics
    Contact
    AbstractShow full text abstract about We show that the unit normal bundle of a smooth boundary of ...»
    We show that the unit normal bundle of a smooth boundary of an attractor for random dynamical systems of a certain natural class is a Legendrian invariant manifold of a deterministic map which preserves a contact structure. In this framework, random dynamics can be described and analyzed by purely deterministic means.
    Lecture
  • Date:27ThursdayMarch 2025

    Simulating high-temperature superconductivity in a triangular moiré lattice

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    Time
    11:15 - 12:15
    Location
    Physics Weissman Auditorium
    LecturerProf. Kin Fai Mak
    Light refreshments at 11:00
    Organizer
    Department of Condensed Matter Physics
    AbstractShow full text abstract about <p>Moiré materials built on transition metal dichalcog...»
    <p>Moiré materials built on transition metal dichalcogenide semiconductors have emerged as a tunable platform for simulating the Hubbard model on a triangular lattice. A natural question arises: Can the platform be tuned to yield a phase diagram similar to that in high-temperature cuprate superconductors? In this talk, I will discuss the emergence of “high-temperature” superconductivity near the Mott transition in a triangular moiré lattice with intermediate coupling strength. The emergent doping-temperature phase diagram looks remarkably similar to that in cuprate superconductors. I will also discuss the evolution of the phase diagram by tuning the band structure of the material by gating. The results could provide a new angle for understanding the phenomenon of high-temperature superconductivity in strongly correlated materials.&nbsp;</p><p>&nbsp;</p>
    Colloquia
  • Date:27ThursdayMarch 2025

    Regulation of immune cell function in tumor microenvironment of triple-negative breast cancer

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    Time
    14:00 - 15:00
    Location
    Max and Lillian Candiotty Building
    Auditorium
    LecturerProf. Idit Shachar
    Organizer
    Dwek Institute for Cancer Therapy Research
    Lecture
  • Date:27ThursdayMarch 2025

    Metabolism, Clonality and Immunotherapy: A Single-Cell PerspectiveTo be announced

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    Time
    15:00 - 16:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium Rm. 191
    LecturerDr. Keren Yizhak
    Faculty of Medicine, Technion - Israel Institute of Technology, Haifa
    AbstractShow full text abstract about <p>Understanding why some patients respond to immune c...»
    <p>Understanding why some patients respond to immune checkpoint therapy while others do not remains a critical challenge in cancer research. This talk will explore three key studies that shed light on this question. First, we uncover metabolic predictors of response to checkpoint blockade therapy, revealing how tumor and immune cell metabolism shape treatment outcomes. Next, we present a single-cell meta-analysis of T cell clonal dynamics, highlighting their role in immunotherapy success. Finally, we introduce scXpand, a machine-learning approach for predicting T cell clonality from scRNA-seq, offering a novel tool to enhance immunotherapy research and precision medicine.</p>
    Lecture
  • Date:27ThursdayMarch 2025

    PhD defense- Eliran offer

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    Time
    15:00 - 17:00
    Title
    Viral and bacterial synergy in pathogenicity expedites algal bloom demise
    Location
    Nella and Leon Benoziyo Building for Plant and Environmental Sciences
    690
    LecturerEliran Soffer
    Contact
    Academic Events
  • Date:27ThursdayMarch 2025

    Vision and AI

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    Time
    16:30 - 17:30
    Title
    Decomposing Images through Compositional Energy Functions
    LecturerYilun Du
    Google Deepmind, Harvard
    Organizer
    Department of Computer Science and Applied Mathematics
    Contact
    AbstractShow full text abstract about Given a distribution of images, how can we can decompose the...»
    Given a distribution of images, how can we can decompose the data into a set of underlying components? In this talk, I'll present an approach that decomposes images into a underlying composable energy functions. I'll illustrate how energy functions allow us to represent both global components of an image, such as lighting as well as local components such as objects. I'll further show how we leverage pretrained vision models to infer these components. Finally, I'll illustrate how discover components can be recombined to form a variety of images substantially different than those seen at training time.

    Speaker's bio:

    Yilun Du is an incoming assistant professor at Harvard and is currently a senior research scientist at Google Deepmind. He received has PhD and BS from MIT and was supported by a NSF graduate fellowship.
    Lecture
  • Date:27ThursdayMarch 2025

    Rona Kenan at Sela

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    Time
    21:00 - 22:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:29SaturdayMarch 2025

    A Visitor for Bear | Mediatheque Theater

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    Time
    11:00 - 12:00
    Location
    Michael Sela Auditorium
    Homepage
    Contact
    Cultural Events
  • Date:30SundayMarch 2025

    Special Guest Seminar - Dr. Thierry Nordmann

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    Time
    11:15 - 12:15
    Title
    Unraveling the Molecular Architecture of the Skin for Personalized Medicine
    Location
    Wolfson Auditorium
    LecturerDr. Thierry Nordmann
    Organizer
    Department of Molecular Cell Biology
    Contact
    Lecture
  • Date:30SundayMarch 2025

    The Clore Center for Biological Physics

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    Time
    12:45 - 14:30
    Title
    An information content principle explains regulatory patterns of human gene expression across tissues.
    Location
    Nella and Leon Benoziyo Physics Library
    LecturerProfessor Yitzhak Pilpel
    Lunch at 12:45
    Contact
    AbstractShow full text abstract about <p>In my talk I will introduce a novel framework that ...»
    <p>In my talk I will introduce a novel framework that applies a principle from information theory, that of Minimum Description Length (MDL), to understand how regulation of human gene expression across organs, tissues is shaped by regulatory architecture.</p><p>Examination of expression patterns of human genes across the body reveals an intriguing duality: While many genes are expressed in only one tissue, others, known as “housekeeping genes”, are ubiquitously expressed in essentially every tissue. Yet, interestingly, a considerable portion of the genes are on the mid-range, deliberately expressed in many tissues but are also absent in many others.</p><p>Intuitively, in human language terms, specifying the expression program of the genes on the two ends of the spectrum requires a short description – e.g. “expressed in all tissues”, or “expressed only in brain”. Yet specifying the expression of genes in the middle of the scale requires longer description, or a longer MDL, having to specify in each tissue if the gene is expressed or not, and at what level. We sought to measure regulatory complexity of each human gene and examine if the MDL principle predicts and explains regulatory complexity. Our findings lend support to the MDL principle’s prediction. Our measure of regulatory complexity of a gene’s expression pattern can be predicted by quantifying its regulatory information content. In the talk we shall discuss evolutionary implications to the development of multi-cellularity.</p><p><strong>FOR THE LATEST UPDATES AND CONTENT ON SOFT MATTER AND BIOLOGICAL PHYSICS AT THE WEIZMANN, VISIT OUR&nbsp;WEBSITE:&nbsp;https://www.biosoftweizmann.com/</strong></p><p>&nbsp;</p>
    Lecture
  • Date:30SundayMarch 2025

    It’s an Emergency: What It Means to Be a Scientist in an Era of Climate and Ecological Breakdown

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    Time
    13:00 - 14:00
    Title
    IES- Institute For Environmental Sustainability Initiative seminar series 2025-2026
    Location
    Nella and Leon Benoziyo Building for Plant and Environmental Sciences
    690
    LecturerDr. Avner Gross
    Organizer
    The Institute for Environmental Sustainability
    Lecture
  • Date:31MondayMarch 2025

    Scientific Council Meeting

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    Time
    10:00 - 12:00
    Location
    The David Lopatie Conference Centre
    KIMEL
    Contact
    Academic Events
  • Date:31MondayMarch 2025

    Decoding the molecular mechanism of histone modification

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Cynthia Wolberger
    Department of Biophysics and Biophysical Chemistry, The Johns Hopkins University
    Organizer
    Department of Chemical and Structural Biology
    Homepage
    Contact
    AbstractShow full text abstract about <p>Post-translational modifications of histones play a...»
    <p>Post-translational modifications of histones play a central role in regulating all cellular processes requiring access to DNA. Monoubiquitinated histone H2B-K120 is a hallmark of actively transcribed genes that plays multiple roles in activating transcription, while monoubiquitinated histone H2A-K119 is abundant in heterochromatin, which is transcriptionally silent. Our structural studies have revealed how histone H2B is specifically ubiquitinated and deubiquitinated, and ubiquitinated H2B stimulates histone methylation. We have also shown how ubiquitin can regulate access to the nucleosome acidic patch, a hotspot for interactions with other chromatin-modifying enzymes. I will also discuss recent studies of a histone kinase that has an unusual mode of binding nucleosomes.</p>
    Colloquia
  • Date:01TuesdayApril 2025

    Confident modeling and manipulation of unconfident interactions

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    Time
    14:00 - 15:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Ora Furman
    Organizer
    Department of Chemical and Structural Biology
    Lecture
  • Date:01TuesdayApril 2025

    Sela Jazz Bar #4 From East to West I Turkiz Ensemble

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    Time
    21:00 - 22:15
    Location
    Michael Sela Auditorium
    Homepage
    Contact
    Cultural Events
  • Date:02WednesdayApril 2025

    students seminar series- Azrieli

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    Time
    10:30 - 12:30
    Location
    Camelia Botnar Building
    Contact
    Lecture
  • Date:02WednesdayApril 2025

    Life Sciences Luncheon

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    Time
    12:30 - 14:00
    Title
    Prof. Ziv Shulman
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    LecturerProf. Ziv Shulman
    Antibody evolution in cancer 
    Contact
    Lecture
  • Date:03ThursdayApril 2025

    אירוע התנדבות מכוני

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    Time
    09:00 - 13:00
    Location
    מחוץ למכון
    Contact
    Cultural Events
  • Date:03ThursdayApril 2025

    Bioinformatics Unit at LSCF: Recent highlights, Single-Cell Insights, and AI Solutions for bioimaging

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    Time
    09:00 - 10:00
    Location
    Candiotty Auditorium
    LecturerDr. Dena Leshkowitz, Dr. Ido Azuri
    Organizer
    Department of Life Sciences Core Facilities
    Lecture

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