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תוצאות חיפוש לאירועים

  • Date:03ראשוןמרץ 2024

    The Clore Center for Biological Physics

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    שעה
    13:15 - 14:30
    כותרת
    A Statistical Physics Approach to Bacteria under Strong Perturbations
    מיקום
    ספרית הפיסיקה על שם נלה וליאון בנוזיו
    מרצה
    Prof. Nathalie Q. Balaban
    Racah Institute of Physics, The Hebrew University
    מארגן
    מרכז לפיסיקה ביולוגית עש קלור
    צרו קשר
    פרטים נוספיםShow full text description of refreshments will be served at 12:45...»
    refreshments will be served at 12:45
    תקצירShow full text abstract about Statistical physics successfully accounts for phenomena invo...»
    Statistical physics successfully accounts for phenomena involving a large number of components using a probabilistic approach with predictions for collective properties of the system. While biological cells contain a very large number of interacting components, (proteins, RNA molecules, metabolites, etc.), the cellular network is understood as a particular, highly specific, choice of interactions shaped by evolution, and therefore difficultly amenable to a statistical physics description. Here we show that when a cell encounters an acute but non-lethal stress, its perturbed state can be modelled as random network dynamics. Strong perturbations may therefore reveal the dynamics of the underlying network that are amenable to a statistical physics description. We show that our experimental measurements of the recovery dynamics of bacteria from a strong perturbation can be described in the framework of physical aging in disordered systems (Kaplan Y. et al, Nature 2021). Further experiments on gene expression confirm predictions of the model. The predictive description of cells under and after strong perturbations should lead to new ways to fight bacterial infections, as well as the relapse of cancer after treatment.
    הרצאה
  • Date:03ראשוןמרץ 2024

    The multimodal regulation of liver glucose metabolism

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    שעה
    15:00 - 16:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצה
    Dr. Kfir Sharabi
    The Institute of Biochemistry, Food Science, and Nutrition. The Robert H. Smith Faculty of Agriculture, Food and Environment. The hebrew University of Jerusalem.
    מארגן
    מדעי החיים
    Metabollic Research Forum
    צרו קשר
    הרצאה
  • Date:04שנימרץ 2024

    Foundations of Computer Science Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Towards general-purpose program obfuscation via local mixing
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Ran Canetti
    Boston University
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    Seminar
    צרו קשר
    תקצירShow full text abstract about We explore the possibility of obtaining general-purpose prog...»
    We explore the possibility of obtaining general-purpose program obfuscation for all circuits by way of making only simple, local, functionality-preserving random perturbations in the circuit structure. Towards this goal, we use the additional structure provided by reversible circuits,  but no additional algebraic structure.


    We start by formulating a new (and relatively weak) obfuscation task regarding the ability to obfuscate  random circuits of  bounded length.  We call such obfuscators  Random Input
    הרצאה
  • Date:05שלישימרץ 2024

    50 Shades of Molecular Modeling in Biomolecular Sciences

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    שעה
    10:00 - 11:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    Cafeteria
    מרצה
    Dr. Sofya Lushchekina
    Dr. Sofya Lushchekina, Dept. of Brain Sciences, Weizmann Institute of Science
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    פרטים נוספיםShow full text description of Scientific Consultant Israel Silman (invited by Moshe Golds...»
    Scientific Consultant
    Israel Silman (invited by Moshe Goldsmith)
    תקצירShow full text abstract about The presentation will cover a spectrum of current applicatio...»
    The presentation will cover a spectrum of current applications of atomistic molecular modeling methods in biomolecular problems. Examples of applications of molecular docking, molecular dynamics, combined quantum mechanics/molecular mechanics and dynamics methods, enhanced sampling, and coarse-graining methods, recent machine learning protein structure prediction methods for studying protein structure and dynamics, protein-ligand and protein-protein interactions, and mechanisms of enzymatic reactions will be considered. The advantages and limitations of different computational methods will be discussed.

    הרצאה
  • Date:05שלישימרץ 2024

    Machine learning for protein functional site annotation and peptide binder design

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    שעה
    14:00 - 15:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצה
    Dr. Jerome Tubiana
    Blavatnik School of Computer Science, Tel Aviv University
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    צרו קשר
    הרצאה
  • Date:06רביעימרץ 2024

    NEUROMORPHOCHIP ORGANOIDS REVEAL A NOVEL MECHANISM FOR MICROCEPHALY

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    שעה
    10:00 - 11:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצה
    Prof. Orly Reiner
    Department of Molecular Genetics
    צרו קשר
    הרצאה
  • Date:07חמישימרץ 2024

    Innovation in the Weizmann Genomics Core – next generation technology outreach

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    שעה
    09:00 - 10:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצה
    Dr. Hadas Keren-Shaul
    Genomics, Dept. of LSCF / G-INCPM
    מארגן
    המחלקה לתשתיות מחקר מדעי החיים
    צרו קשר
    הרצאה
  • Date:07חמישימרץ 2024

    Geometric Functional Analysis and Probability Seminar

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    שעה
    13:30 - 14:30
    כותרת
    Some limit theorems for U-max statistics with geometric structure
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Katya Simarova
    St. Petersburg
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about U-max statistics, introduced by Lao and Mayer in 2008, serve...»
    U-max statistics, introduced by Lao and Mayer in 2008, serve as an extreme-value analogue of U-statistics. Natural examples of U-max statistics include the maximum of random variables and the diameters of convex hulls. However, more complex examples exist, such as the maximal perimeter or area of an m-polygon calculated over all possible m-sets of points from a random sample. This talk will focus on specific U-max statistics that possess a geometric structure and derive limit theorems for them, with the Weibull distribution as a limit.
    הרצאה
  • Date:10ראשוןמרץ 2024

    Chemical and Biological Physics Guest seminar

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    שעה
    16:00 - 17:00
    כותרת
    Photodynamics of molecular probes in solutions, cells, and organic surfaces
    מיקום
    בניין פרלמן למדעי הכימיה
    Room 404
    מרצה
    Prof. Oleg Vasyutinskii
    Peter the Great St. Petersburg Polytechnic University
    מארגן
    המחלקה לפיסיקה כימית וביולוגית
    צרו קשר
    תקצירShow full text abstract about The lecture presents recent results obtained in the laborato...»
    The lecture presents recent results obtained in the laboratory of Prof. Oleg Vasyutinskii in the Ioffe Institute, St.Petersburg, Russia along several directions of application of modern laser techniques for investigation of the dynamics of molecules relevant for biology and medicine. The particular directions under discussion will be as follows.
    • Investigation of energy transfer in the excited states of molecular probes in solutions by means of polarized fluorescence spectroscopy.
    • Pump-and-probe polarization modulation spectroscopy for investigation of sub-picosecond dynamics in excited biomolecules.
    • Dynamics of singlet oxygen generation and degradation in solutions and on organic surfaces.

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  • Date:12שלישימרץ 2024

    Travelling waves or sequentially activated modules: mapping the granularity of cortical propagation

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    שעה
    12:30 - 13:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצה
    Dr. Mark Shein-Idelson
    Dept of Neurobiology, Faculty of Life Sciences Tel Aviv University
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    פרטים נוספיםShow full text description of Host: Dr. Yoav Livneh yoav.livneh@weizmann.ac.il tel:6230 ...»
    Host: Dr. Yoav Livneh yoav.livneh@weizmann.ac.il
    tel:6230

    For accessibility issues:naomi.moses@weizmann.ac.il
    תקצירShow full text abstract about : Numerous studies have identified travelling waves in the c...»
    : Numerous studies have identified travelling waves in the cortex and suggested they play important roles in brain processing. These waves are most often measured using macroscopic methods that do not allow assessing wave dynamics at the single neuron scale and analyzed using techniques that smear neuronal excitability boundaries. In my talk, I will present a new approach for discriminating travelling waves from modular activation. Using this approach I will show that Calcium dynamics in mouse cortex and spiking activity in turtle cortex are dominated by modular activation rather than by propagating waves. I will then show how sequentially activating two discrete brain areas can appear as travelling waves in EEG simulations and present an analytical model in which modular activation generates wave-like activity with variable directions, velocities, and spatial patterns. I will end by illustrating why a careful distinction between modular and wave excitability profiles across scales will be critical for understanding the nature of cortical computations.
    הרצאה
  • Date:12שלישימרץ 2024

    Seminar for PhD thesis defense

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    שעה
    13:00 - 14:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצה
    Gabriela Lobinska
    מארגן
    המחלקה לגנטיקה מולקולרית
    צרו קשר
    הרצאה
  • Date:13רביעימרץ 2024

    ABC CHATS: Ronit Harpaz - From Idea to a Startup

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    שעה
    14:00 - 16:00
    כותרת
    An entrepreneur’s story
    מיקום
    בניין על-שם גרשון ואסתר סאגאן
    Lounge
    מרצה
    Ronit Harpaz
    Co-Founder & CEO of Endoron Medical
    צרו קשר
    פרטים נוספיםShow full text description of Ronit Harpaz will share her story of building a startup from...»
    Ronit Harpaz will share her story of building a startup from the ground up and answer questions such as: Where to begin? What makes good partners? Am I suitable for the bumpy ride? and more.
    Join our ABC CHATS where CEO's share their ABC’s on scientific leadership, breakthroughs and failures throughout their personal stories


    הרצאה
  • Date:14חמישימרץ 2024

    PhD Thesis Defense by Tomer Milo (Prof. Uri Alon Lab)

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    שעה
    13:00 - 15:00
    כותרת
    Design principles of physiological tissue-level circuits
    מיקום
    בניין וולפסון למחקר ביולוגי
    Auditorium
    מרצה
    Tomer Milo (Prof. Uri Alon Lab)
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:14חמישימרץ 2024

    The roles of RNA processing in cancer initiation and progression and its modulation for cancer therapy

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    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצה
    Prof. Rotem Karni
    Chair, Department of Biochemistry and Molecular Biology, Hebrew University Faculty of Medicine
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    Cancer Research Club
    צרו קשר
    פרטים נוספיםShow full text description of Meeting URL: https://weizmann.zoom.us/j/5065402023?pwd=a3Z6K...»
    Meeting URL: https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09


    הרצאה
  • Date:17ראשוןמרץ 202421חמישימרץ 2024

    M2C2 - Marine Microbial Chemical Communication

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    שעה
    08:00 - 08:00
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    יושב ראש
    Assaf Vardi
    צרו קשר
    כנסים
  • Date:18שנימרץ 2024

    Atom-Probe Tomography and its Myriad Applications in Chemistry

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    שעה
    11:00 - 12:15
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצה
    Prof. David N. Seidman
    McCormick School of Engineering, Northwestern University
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    דף בית
    צרו קשר
    תקצירShow full text abstract about atom-probe tomograph (APT) can dissect a nanotip shaped spec...»
    atom-probe tomograph (APT) can dissect a nanotip shaped specimen (radius <50 nm) atom-byatom
    and by atomic plane-by-plane, and then the dissected volume can be reconstructed from the
    positions of the atoms in three-dimensions (3-Ds), with atomic-scale resolution plus assigning an
    elemental or isotopic identity to each atom with a detection efficiency of ~80% (E. W. Mueller, J. A.
    Panitz, S. B. McLane, 1968). To be specific an APT consists of a field-ion microscope (FIM), which
    one uses to observe individual atoms on the surface of a nanotip with atomic resolution ( E. W. Mueller
    and Bahadur, 1956).plus a special time-of-flight (TOF) mass spectrometer to determine the mass-tocharge
    state ratio (m/n) of each charged field-evaporated atomic or molecular ion: the nanotip is at a
    positive potential with respect to ground. In a modern APT a picosecond ultraviolet (UV) laser,
    operating in a pulsed mode, is utilized to thermally activate field-evaporated atoms from the surface of
    a nanotip as positively charged ions. The ions are detected using a microchannel plate (MCP) detector,
    with a gain of 107, which serves as the primary detector of the evaporated ions, which, in turn, yields
    their m/n values from their TOFs. Behind the primary detector is a secondary detector, which yields
    the 2-D positions of the field-evaporated ions in different {hkl} planes on the surface of a nanotip,
    which to first order is a highly faceted hemisphere. With continuing pulsed field-evaporation the atoms
    in the bulk of a nanotip are sequentially detected, thereby yielding the 3rd dimension and hence the
    name atom-probe tomograph (APT). In addition to the functional principles of an APT, select research
    applications are presented.
    סימפוזיונים
  • Date:18שנימרץ 2024

    Foundations of Computer Science Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Toward Better Depth Lower Bounds: A KRW-like theorem for Strong Composition
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Or Meir
    University of Haifa
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    Seminar
    צרו קשר
    תקצירShow full text abstract about One of the major open problems in complexity theory is provi...»
    One of the major open problems in complexity theory is proving super-logarithmic lower bounds on the depth of circuits. Karchmer, Raz, and Wigderson (Computational Complexity 5(3/4), 1995) suggested approaching this problem by proving that depth complexity of a composition of two functions is roughly the sum of their individual depth complexities. They showed that the validity of this conjecture would imply the desired lower bounds. 

    The intuition that underlies the KRW conjecture is that composition should behave like a "direct-sum problem", in a certain sense, and therefore the depth complexity of the composition should be the sum of the individual depth complexities. Nevertheless, there are two obstacles toward turning this intuition into a proof: first, we do not know how to prove that the composition must behave like a direct-sum problem
    הרצאה
  • Date:19שלישימרץ 2024

    iSCAR Breakfast Seminar

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    שעה
    09:00 - 10:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מארגן
    המחלקה לאימונולוגיה ורגנרציה ביולוגית
    צרו קשר
    הרצאה
  • Date:19שלישימרץ 2024

    New approaches to glycan synthesis and glycan-based biosensing

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    שעה
    14:00 - 15:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצה
    Prof. Mattan Hurevich
    Institute of Chemistry Hebrew University
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    צרו קשר
    הרצאה
  • Date:20רביעימרץ 2024

    Employing the Hegelian Aufhebung Principle for Predicting New Catalytic Pathways

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    שעה
    11:00 - 12:00
    מיקום
    בניין פרלמן למדעי הכימיה
    Room 404
    מרצה
    Prof. Anatoly Frenkel
    Stony Brook University and Brookhaven National Laboratory
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    צרו קשר
    תקצירShow full text abstract about Understanding mechanisms of work for a wide range of applied...»
    Understanding mechanisms of work for a wide range of applied nanomaterials begins with identifying “active units” in operating conditions, zooming in on the “active sites” and ends with a model explaining their role for functioning of the material or device. There are two main hurdles that we are particularly interested in overcoming: 1) heterogeneity of active species and sites and 2) their dynamics that can be directly responsible for their mechanisms. One possible method, ideally suitable for capitalizing on these challenges for rational design of new catalytic pathways, is the Aufhebung (sublation) principle from the Hegelian dialectics. It describes the process of advancing knowledge by integrating the two opposites: the thesis and antithesis. We adopt this principle to leverage the inherent heterogeneity of catalytic active species and active sites in metal catalysts for understanding and predicting new catalytic pathways for CO and CO2 conversion reactions. Starting with atomically dispersed (the thesis) Pt on ceria support, we use multimodal, operando characterization for monitoring formation of nanoparticles (the antithesis), identify reaction active species and unique active sites at the metal-support interface. With this knowledge, we design the “single-atoms” catalysts (synthesis) possessing the same active sites and enhanced stability in reaction conditions. I will highlight the role of oxygen vacancies for enhancing the dynamicity of Pt atoms and opening new reaction pathways for direct and reverse water gas shift reactions and CO oxidation reaction.
    הרצאה

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