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Date:19שניאפריל 2021הרצאה
Uncovering the Boundaries of Olfactory Perception
More information שעה 15:00 - 16:00מרצה Aharon Ravia (PhD Thesis Defense)
Prof. Noam Sobel Lab, Dept of Neurobiology Prof. David Harel Lab, Dept of Computer Science and Applied Mathematics WISמארגן המחלקה לנוירוביולוגיהצרו קשר פרטים נוספים Show full text description of Zoom link to join: https://weizmann.zoom.us/j/93360836031?pw...» Zoom link to join: https://weizmann.zoom.us/j/93360836031?pwd=dDZEdTQ1QUkxUVVONVErVm9CcUJWQT09
Meeting ID: 933 6083 6031
Password: 591230
תקציר Show full text abstract about The question of how to measure a smell has troubled scientis...» The question of how to measure a smell has troubled scientists for over a century. It was none other than Alexander Graham Bell that raised the challenge: "we have very many different kinds of smells, all the way from the odor of violets and roses up to asafoetida. But until you can measure their likenesses and differences you can have no science of odor”. Such a measure of smell can be naturally derived from a model of olfactory perceptual quality space, and several such models have recently been put forth. These typically rely on finding mathematical rules that link odorant structure to aspects of odor perception.
Here, I collected 49,788 perceptual odor estimates from 199 participants, and built such a model, finalizing a physicochemical measure of smell. This measure, expressed in radians, predicts real-world odorant pairwise perceptual similarity from odorant structure alone. Using this measure, I met Bell's challenge by accurately predicting the perceptual similarity of rose, violet and asafoetida, from their physicochemical structure. Next, based on thousands of comparisons, I identified a cutoff in this measure, below 0.05 radians, where discrimination between pairs of mixtures becomes highly challenging. To assess the usefulness of this measure, I investigated whether it can be used to create olfactory metamers, namely non-overlapping molecular compositions that share a common percept. Characterizing the link between physical structure and ensuing perception in vision and audition, and the creation of perceptual entities such as metamers, was important towards understanding their underlying dimensionality, brain mechanisms, and towards their ultimate digitization. I suggest that olfactory metamers can similarly aid these goals in olfaction.
Zoom link to join: https://weizmann.zoom.us/j/93360836031?pwd=dDZEdTQ1QUkxUVVONVErVm9CcUJWQT09
Meeting ID: 933 6083 6031
Password: 591230
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Date:20שלישיאפריל 2021הרצאה
ILASOL 2021 Conference
More information שעה כל היוםמיקום בניין ארתור ורושל בלפר למחקר ביורפואי
Botnar Auditoriumמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:20שלישיאפריל 2021הרצאה
The hydrological paradox - why the whole is less than the sum of its parts?
More information שעה כל היוםמיקום https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09מרצה Erwin Zehe
KITמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about Hydrological systems are inherently non-linear and exhibit a...» Hydrological systems are inherently non-linear and exhibit an enormous structural and functional heterogeneity. Strikingly, we can nevertheless successfully simulate stream flow generation and the water balance of river catchments with rather simple models that are largely incompatible with the frequently reported subscale process heterogeneity and non-linearity. Here we argue that subscale structural heterogeneity and randomness must not prevent the emergence of functional simplicity. On the contrary, we found simplicity to emerge at rather small scales, reflecting self-organization in hydrological functioning not despite but due to subscale small-scale heterogeneity and the dissipative nature of hydrological process. While we acknowledge that hydrological landscapes are heterogeneous, they are by no means a random product. Catchments exhibit a considerable spatial organisation, which manifests through structured patterns of topography, soil, vegetation, self-similar surface and subsurface drainage networks and most prominently through ubiquitous preferential flow phenomena. While this organized “catchment from” does strongly determine present storage, cycling and release of water, energy and chemical species, this catchment form has in turn been shaped by of water, energy, and nutrients of the past. Is this “co-evolution” just chance or manifested self-organization? This question has been inspiring many scientists to search for thermodynamic principles that link form and function in the Earth system. Here we will present evidence that a thermodynamic and information theoretic perspective opens up new avenues for (i) diagnosing and explaining self-organization in hydrological dynamics, (i) upscaling of constituting relations and (i) using thermodynamic optimality for hydrological predictions. -
Date:20שלישיאפריל 2021הרצאה
Clathrin-mediated endocytosis: From the textbook model toward understanding the biological diversity of the process
More information שעה 10:00 - 11:00מיקום בניין לביוכימיה על שם נלה וליאון בנוזיומרצה Prof. Marko Kaksonen
Department of Biochemistry at the University of Genevaמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Zoom LInk: https://weizmann.zoom.us/j/95881429481?pwd=Vkxw...» Zoom LInk:
https://weizmann.zoom.us/j/95881429481?pwd=VkxwUmg1Z2ErZmhpZDJqMTZwellGZz09 -
Date:20שלישיאפריל 2021הרצאה
New insights on continuous attractor neural networks
More information שעה 12:30מרצה Prof. Yoram Burak
Racah Institute of Physics and Edmond and Lily Safra Center for Brain Sciences The Hebrew University of Jerusalemמארגן המחלקה לנוירוביולוגיהצרו קשר פרטים נוספים Show full text description of Zoom link to join- https://weizmann.zoom.us/j/96608033618?p...» Zoom link to join-
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
תקציר Show full text abstract about One of the most fundamental concepts in theoretical neurosci...» One of the most fundamental concepts in theoretical neuroscience is that of an attractor neural network, in which recurrent synaptic connectivity constraints the joint activity of neurons into a highly restricted repertoire of population activity patterns. In continuous attractor networks, these activity patterns span a continuous, low-dimensional manifold. I will survey two recent works from my group that are related to this concept. The first work is concerned with fixational eye drifts, a form of eye motion that occurs between saccades and is characterized by smooth, yet random, diffusive-like motion. This motion is tiny compared to saccadic eye motion, yet it is highly consequential for high-acuity vision. Even though fixational drift has been identified at least as early as the 19th century, its mechanistic origins have remained completely unknown. We hypothesize that the main drive for fixational drifts arises in diffusive motion along a line-attractor memory network - the oculomotor network, which is responsible for maintaining a fixed activation of the ocular muscles between saccades. I will present evidence in support of this hypothesis, coming from electrophysiology in monkeys and from theoretical modeling. The second work is concerned with the ability of a single recurrent neural network to express activity patterns that span multiple yet distinct continuous manifolds, a question that has been of interest in the context of spatial coding, across multiple environments, in area CA3 of the hippocampus.
Zoom link to join-
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070 -
Date:20שלישיאפריל 2021הרצאה
From light-harvesting to assembly: Modularity and heterogeneity in photosynthetic antenna systems
More information שעה 15:00 - 16:00כותרת Guest Seminar via Zoomמיקום https://weizmann.zoom.us/j/99097904761?pwd=MitYaVJjL0Y4OFU3NWRVeCtDNkkyZz09 Password 247214מרצה Dr. Hila Toporik
School of Molecular Sciences/The Biodesign Institute, The Center for Applied Structural Discovery, Arizona State Universityמארגן המחלקה למדעי הצמח והסביבהצרו קשר פרטים נוספים Show full text description of Host: Prof. Asaph Aharoni...» Host: Prof. Asaph Aharoni -
Date:22חמישיאפריל 2021סימפוזיונים
Atmospheric Dynamics on Jupiter: New Results from the Juno Mission
More information שעה 11:15 - 12:30מיקום https://weizmann.zoom.us/j/94477142638?pwd=aWNlZGVzNmdJdnJVZVNZUi9sZ0VBZz09מרצה Yohai Kaspi
WISמארגן הפקולטה לפיסיקהצרו קשר תקציר Show full text abstract about NASA's Juno Mission is now completing its 5 year nomina...» NASA's Juno Mission is now completing its 5 year nominal mission around Jupiter, orbiting the planet in an eccentric polar-orbit every 53 days. One of the prime mission objectives is better understanding the atmospheric dynamics through gravitational, microwave, infrared and magnetic measurements. In this talk, we will focus on three new results explaining different aspects of the dynamics on Jupiter. First, infrared imaging data revealed that Jupiter’s poles are surrounded by 5 cyclones around the North Pole and 8 cyclones around the South Pole. We explain the location, size and stability of these circumpolar cyclones based on vorticity dynamics. Second, using microwave data, revealing Jupiter’s deep ammonia abundance structure, we show that Jupiter has 8 meridional circulation cells in each hemisphere. These cells resemble in their governing physics Earth's midlatitude Ferrel cells, and relate to the observed red and white belts and zones at Jupiter’s cloud-level. Finally, using Juno’s gravity measurements we constrain the depth of Jupiter’s east-west jet-streams, and the depth (mass) of the most iconic vortex in the Solar system — Jupiter’s Great Red Spot. Overall, this unique multiple instrument dataset allows now explaining the governing physics of several outstanding aspects of Jupiter’s internal and atmospheric dynamics. We will also compare the dynamics to those of Saturn, generalizing some of the this new understanding. -
Date:22חמישיאפריל 2021הרצאה
Therapeutic Exploitation of Metabolic Vulnerabilities of Cancer
More information שעה 14:00 - 15:00מרצה Prof. Eyal Gottlieb
Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technologyמארגן המכון לחקר הטיפול בסרטן עש דואק
Cancer Research Clubצרו קשר פרטים נוספים Show full text description of https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2...» https://weizmann.zoom.us/j/5065402023?pwd=a3Z6KzRCU0xJaUFoM2Y5emZwZm1oZz09 -
Date:25ראשוןאפריל 2021הרצאה
Seminar for Thesis defense of Gat Krieger
More information שעה 13:30 - 14:30כותרת Evolution of gene regulation in yeast through changes in transcription factor binding and gene expressionמיקום https://weizmann.zoom.us/j/93751101380?pwd=QWJRQzVSZXVOWitiRWdJU1ZMSlFSQT09מרצה Gat Kriegerמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:26שניאפריל 2021הרצאה
Physics-guided machine-learning parameterizations of subgrid processes for climate modeling
More information שעה 14:00מיקום https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09מרצה Janni Yuval
Earth, Atmospheric and Planetary Sciences MIT school of Scienceמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about Global climate models represent small-scale processes, such ...» Global climate models represent small-scale processes, such as clouds and convection, using subgrid models known as parameterizations. Traditional parameterizations are usually based on simplified physical models, and inaccuracies in these parameterizations are a main cause for the large uncertainty in climate projections. One alternative to traditional parameterizations is to use machine learning to learn new parameterizations which are data driven. However, machine-learning parameterizations might violate physical principles and often lead to instabilities when coupled to an atmospheric model. I will show how machine learning algorithms, such as neural networks and random forests, can be used to learn new parameterizations from the output of a three-dimensional high-resolution atmospheric model, while obeying physical constraints such as energy conservation. Implementing these parameterizations in the atmospheric model at coarse resolution leads to stable simulations that replicate the climate of the high-resolution simulation, and capture important statistics such as precipitation extremes. I will also discuss how machine-learning parameterizations can give further insights into the parameterization problem. Specifically, I will show that failures of machine-learning parameterizations can be used to better understand the relationship between large-scale fields and subgrid processes. -
Date:27שלישיאפריל 2021הרצאה
To be announced
More information שעה 10:00 - 11:00מיקום בניין לביוכימיה על שם נלה וליאון בנוזיו
Cafeteriaמרצה Oshrat Galibov Levi
Dept. of Biomolecular Sciences-WISמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Zoom LInk: https://weizmann.zoom.us/j/95881429481?pwd=Vkxw...» Zoom LInk:
https://weizmann.zoom.us/j/95881429481?pwd=VkxwUmg1Z2ErZmhpZDJqMTZwellGZz09 -
Date:27שלישיאפריל 2021הרצאה
Deposition of Gypsum Deltas at the Holocene Dead Sea by outsalting and paleoclimatic insights
More information שעה 10:00 - 11:00מיקום https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09מרצה Nurit Weber
Department of Earth and Planetary Sciences Weizmann Institute of Sciencesמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about The rapid retreat of the Dead Sea during the past decades le...» The rapid retreat of the Dead Sea during the past decades led the exposure of unique structures of massive gypsum and aragonite crusts: large capes pointing towards the open lake (termed here “gypsum deltas”) and numerous small gypsum mounds scattered on the lake’s exposed shores. Geological field relations, 14C and 34S measurements and thermodynamic calculations provide evidence that the gypsum deltas and the mounds were formed during time-intervals of low lake stands (~420±10 m below mean sea level), when sulfate-rich Ca-chloride brines discharged from the coastal aquifer via saline springs, mixed with the Dead Sea brine and precipitated the gypsum. This mixing process describes a mechanism of “gypsum outsalting”, which is completely different from the conventional view of gypsum as a product of evaporative deposition.
Condition for enhanced saline springs discharge and “gypsum outsalting” occurred in the mid to late Holocene period (~ 6.6 to 0.6 ka), and were mainly intensive at the latest stages of regional aridity cycles when lake level was still low and the Dead Sea salinity was at its highest. The ages of formation of the gypsum structures coincide with times of North Atlantic cooling events and grand solar minima suggesting a direct impact of the latter on the Dead Sea hydrology and high sensitivity of the regional hydrology (controlling lake level) to global solar-related events. The frequency of appearance of the gypsum structures seems to follow the Hallstat Cycle that approached minimum at ~3000 2000 years ago.
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Date:27שלישיאפריל 2021הרצאה
Neural correlates of future weight loss reveal a possible role for brain-gastric interactions
More information שעה 12:30 - 13:30מרצה Prof. Galia Avidan
Dept of Psychology Ben Gurion University of the Negevמארגן המחלקה לנוירוביולוגיהצרו קשר פרטים נוספים Show full text description of Zoom link to join: https://weizmann.zoom.us/j/96608033618?p...» Zoom link to join:
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
תקציר Show full text abstract about Lifestyle dietary interventions are an essential practice in...» Lifestyle dietary interventions are an essential practice in treating obesity, hence neural factors that may assist in predicting individual treatment success are of great significance. Here, in a prospective, open-label, three arms study, we examined the correlation between brain resting-state functional connectivity measured at baseline and weight loss following 6 months of lifestyle intervention in 92 overweight participants. We report a robust subnetwork composed mainly of sensory and motor cortical regions, whose edges correlated with future weight loss. This effect was found regardless of intervention group. Importantly, this main finding was further corroborated using a stringent connectivity-based prediction model assessed with cross-validation thus attesting to its robustness. The engagement of senso-motor regions in this subnetwork is consistent with the over-sensitivity to food cues theory of weight regulation. Finally, we tested an additional hypothesis regarding the role of brain-gastric interaction in this subnetwork, considering recent findings of a cortical network synchronized with gastric activity. Accordingly, we found a significant spatial overlap with the subnetwork reported in the present study. Moreover, power in the gastric basal electric frequency within our reported subnetwork negatively correlated with future weight loss. This finding was specific to the weight loss related subnetwork and to the gastric basal frequency. These findings should be further corroborated by combining direct recordings of gastric activity in future studies. Taken together, these intriguing results may have important implications for our understanding of the etiology of obesity and the mechanism of response to dietary intervention as well as to interoceptive perception.
Zoom link to join:
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:28רביעיאפריל 2021הרצאה
Spotlight on Science Lecture - Travelling The SILC Road: The Non-Coding Path to Nerve Regeneration
More information שעה 11:00 - 12:00כותרת https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5cTA5SU1Ed1VVZnViZ0lUQT09 Password: 193088מיקום https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5cTA5SU1Ed1VVZnViZ0lUQT09מרצה Dr. Rotem Ben-Tov-Perry
Department of Biological Regulationמארגן המחלקה לתשתיות מחקר מדעי החייםצרו קשר פרטים נוספים Show full text description of ZOOM https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5c...» ZOOM
https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5cTA5SU1Ed1VVZnViZ0lUQT09
Password: 193088תקציר Show full text abstract about Travelling The SILC Road: The Non-Coding Path to Nerve Rege...» Travelling The SILC Road:
The Non-Coding Path to Nerve Regeneration -
Date:02ראשוןMay 202103שניMay 2021מועצת המנהלים הבינלאומית
Executive Board and committees meetings 2021
More information שעה כל היוםמיקום פלטפורמה דיגיטליתצרו קשר -
Date:03שניMay 2021סימפוזיונים
Magnetic control over chemical bonds in atomic-wires and molecular junctions
More information שעה 11:00 - 12:00מיקום https://weizmann.zoom.us/j/98063488104?pwd=N3VqTC9sU1A4RHVDZ1dhOGVxbU1iUT09מרצה Prof. Oren Tal
Department of Chemical & Biological Physics, WISמארגן הפקולטה לכימיהצרו קשר תקציר Show full text abstract about Controlling the properties of chemical bonds by an external ...» Controlling the properties of chemical bonds by an external stimulus is a central goal in chemistry. At the level of individual bonds, such control was achieved using light, current, electrochemical potential and electric field. In my talk, I will show that the size and direction of applied magnetic fields can affect bond stability, interatomic distance, and bond-formation probability. This behavior is demonstrated in a variety of atomic wires and single-molecule junctions. The revealed magneto-structural phenomena show that the influence of magnetic interactions on chemical bonds can be dramatic in nanoscale systems. -
Date:03שניMay 2021הרצאה
Cooperative Carbon Capture in Metal–Organic Frameworks
More information שעה 18:00 - 19:00כותרת SAERI - Sustainability and Energy Research Initiative seminar seriesמיקום via zoomמרצה Prof. Jeffrey R. Long
Departments of Chemistry and Chemical & Biomolecular Engineering,University of California, Berkeley, USAמארגן מדרשת פיינברג
Alternative Sustainable Energy Research Initiative (AERI)צרו קשר פרטים נוספים Show full text description of Host: Prof. Ron Milo zoom link: https://weizmann.zoom.us...»
Host: Prof. Ron Milo
zoom link: https://weizmann.zoom.us/j/98545366579?pwd=dXNocENmcFF6TDhld1JqS0RMcHRvQT09
Meeting ID: 985 4536 6579
Password: 12345
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Date:04שלישיMay 202106חמישיMay 2021כנסים
new approaches in virology research
More information שעה 08:00 - 08:00מיקום מרכז כנסים על-שם דויד לופאטי
Kimmel Auditoriumיושב ראש Noam Stern-Ginossarצרו קשר -
Date:04שלישיMay 2021הרצאה
To be announced
More information שעה 12:30מרצה Ivan E de Araujo
Mt. Sinai Hospitalמארגן המחלקה לנוירוביולוגיהצרו קשר פרטים נוספים Show full text description of Zoom link to join- https://weizmann.zoom.us/j/96608033618?p...» Zoom link to join-
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
תקציר Show full text abstract about Zoom link to join- https://weizmann.zoom.us/j/96608033618?p...» Zoom link to join-
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:06חמישיMay 2021סימפוזיונים
Postdocs' colloquium
More information שעה 11:15 - 12:30מיקום https://weizmann.zoom.us/j/94477142638?pwd=aWNlZGVzNmdJdnJVZVNZUi9sZ0VBZz09מרצה Physics postdoctoral fellowsמארגן הפקולטה לפיסיקהצרו קשר תקציר Show full text abstract about TBA ...» TBA