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  • Date:18שלישידצמבר 2018

    Functional stability in a dynamic network – the role of inhibition

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    שעה
    12:30
    מיקום
    בניין לחקר המוח על-שם נלה וליאון בנוזיו
    מרצה
    Prof. Yonatan Loewenstein
    Department of Neurobiology – ELSC Hebrew University of Jerusalem
    מארגן
    המחלקה לנוירוביולוגיה
    צרו קשר
    פרטים נוספיםShow full text description of Benoziyo Brain Research Building Room 113 Host: Dr.Ivo Sp...»
    Benoziyo Brain Research Building Room 113

    Host: Dr.Ivo Spiegel ivo.spiegel@weizmann.ac.il tel: 4415
    For assistance with accessibility issues, please contact naomi.moses@weizmann.ac.il
    תקצירShow full text abstract about According to the synaptic trace theory of memory, activity-i...»
    According to the synaptic trace theory of memory, activity-induced changes in the pattern of synaptic connections underlie the storage of information for long periods. In this framework, the stability of memory critically depends on the stability of the underlying synaptic connections. Surprisingly however, the excitatory synaptic connections, which constitute most of the synapses in the cortex, are highly volatile in the living brain, which poses a fundamental challenge to the synaptic trace theory. We show that in the balanced cortex, patterns of neural activity are primarily determined by the inhibitory connectivity, despite the fact that most synapses and neurons are excitatory. Similarly, we show that the inhibitory network is more effective in storing memory patterns than the excitatory one. As a result, network activity is robust to ongoing volatility of excitatory synapses, as long as this volatility does not disrupt the balance between excitation and inhibition. We thus hypothesize that inhibitory connectivity, rather than excitatory, controls the maintenance and loss of information over long periods of time in the volatile cortex.

    הרצאה
  • Date:18שלישידצמבר 2018

    Translational control of cancer and neurological disease via eIF4E

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    שעה
    14:00 - 15:00
    מיקום
    בניין קמיליה בוטנאר
    Dov Elad Room
    מרצה
    Prof. Nahum Sonenberg
    Department of Biochemistry McGill University, Montreal CANADA
    מארגן
    המחלקה לביולוגיה מבנית
    צרו קשר
    הרצאה
  • Date:19רביעידצמבר 2018

    Weizmann – Princeton – CNRS – HIT Plasma Workshop

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    שעה
    09:45 - 16:00
    מיקום
    בניין הפיסיקה ע"ש עדנה וק.ב. וייסמן
    Amos de-Shalit Room
    מרצה
    Christine Stollberg
    Evolution of the current distribution in a small-scale self-compressing plasma
    מארגן
    המחלקה לפיסיקה של חלקיקים ואסטרופיסיקה
    Plasma Seminar
    צרו קשר
    פרטים נוספיםShow full text description of 09:45 - 10:15 Morning coffee. 10:15 - 11:30 Christine Stol...»
    09:45 - 10:15 Morning coffee.
    10:15 - 11:30 Christine Stollberg (WIS) – “Evolution of the current distribution in a small-scale self-compressing plasma column” + Discussion
    11:30 - 12:45 Amnon Fruchtman, (HIT) – “Escaping current in a Z-pinch” + Discussion
    12:45 - 14:30 Lunch break
    14:30 - 15:45 Nat Fisch (Princeton) – “Some ideas for Weizmann-Princeton collaborations on Z-pinch Physics” + Discussion
    15:45 - 16:00 Afternoon coffee break.
    16:00 Free discussions
    הרצאה
  • Date:20חמישידצמבר 2018

    Annual meeting of the ISBMB

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    שעה
    08:00 - 17:30
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    Kimmel Auditorium
    יושב ראש
    Yifat Merbl
    דף בית
    צרו קשר
    כנסים
  • Date:20חמישידצמבר 2018

    Weizmann – Princeton – CNRS – HIT Plasma Workshop

    More information
    שעה
    09:45 - 16:00
    מיקום
    בניין הפיסיקה ע"ש עדנה וק.ב. וייסמן
    מרצה
    Mikhail Mlodok
    Stratification effects in magnetized multi-ion plasma” + Discussion
    מארגן
    המחלקה לפיסיקה של חלקיקים ואסטרופיסיקה
    Plasma Seminar
    צרו קשר
    פרטים נוספיםShow full text description of 09:45 - 10:15 Morning coffee. 10:15 - 11:30 Mikhail Mlodok...»
    09:45 - 10:15 Morning coffee.
    10:15 - 11:30 Mikhail Mlodok (Princeton) – “Stratification effects in magnetized multi-ion plasma” + Discussion
    11:30 - 12:45 Evgeny Stambulchik (WIS) – “Forbidden-line satellites as a probe of HED plasmas" + Discussion
    12:45 - 14:30 Lunch break
    14:30 - 15:45 Ramy Doron ( TBA ) + Discussion 15:45 - 16:00 Afternoon coffee break.
    16:00 Free discussions and closing remarks
    הרצאה
  • Date:20חמישידצמבר 2018

    Effects of electron spin dynamics on DNP at 7 Tesla

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    שעה
    10:00 - 11:00
    מיקום
    בניין פרלמן למדעי הכימיה
    Shlomo Alexander Science Lounge
    מרצה
    Dr. Ilya Kaminker
    School of Chemistry, The Raymond and Beverly Sackler Faculty of Exact Sciences, TAU
    מארגן
    המחלקה לחומרים ופני שטח
    צרו קשר
    תקצירShow full text abstract about Dynamic Nuclear Polarization (DNP) is the most widespread an...»
    Dynamic Nuclear Polarization (DNP) is the most widespread and ubiquitous technique for signal enhancement in Nuclear Magnetic Resonance (NMR). The gain in signal intensity is achieved by polarization transfer from the highly-polarized electron spins to the nuclear spins of interest. The home-build DNP/EPR spectrometer in the laboratory of Prof. Songi Han at UCSB allowed for the first time direct observation of the electron spin dynamics in the course of DNP experiment at NMR-relevant magnetic field (≥ 7 Tesla); measurement of electron relaxation times T1 and T2 and electron-electron spin diffusion rate by Electron-Electron DOuble resonance (ELDOR) under DNP conditions. I will present how the addition of 200 GHz arbitrary pulse shaping extended the ability to manipulate the electron spins in both EPR and DNP experiments. Specifically, up to a factor of five improvement in DNP performance was observed when a train of chirp pulses (chirp-DNP) was substituted for conventional, continuous wave microwave irradiation. The combination of shaped-pulse ELDOR together with DNP profile lineshape analysis allowed us to conclude that the gain in performance in chirp-DNP is due to recruitment of additional electron spins that participate in DNP via cross effect (CE) mechanism as opposed to the indirect CE (iCE) mechanism that dominates in the conventional CW DNP experiments under similar conditions.
    In addition to serving as the source of the polarization, the electron spins can have other, sometimes detrimental, effects on the NMR spectra such as shifting the position of the peaks (Paramagnetic Shift) and decreasing resolution by linewidth increase (Paramagnetic relaxation) collectively known as paramagnetic effects (PE). We have recently observed the reversal of PE upon microwave irradiation in DNP experiments at liquid helium temperatures. WE suggest that the the origin of the observed effect stems from the REversal of PRE by electron Spin SaturatION (REPRESSION) effect which was traced to the shortening of the electron phase memory time, Tm, with electron spin bath saturation by microwave irradiation.
    הרצאה
  • Date:20חמישידצמבר 2018

    Physics Colloquium

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    שעה
    11:15 - 12:30
    מיקום
    בניין הפיסיקה ע"ש עדנה וק.ב. וייסמן
    Auditorium
    מרצה
    Daniel Savin
    Columbia U.
    מארגן
    הפקולטה לפיסיקה
    צרו קשר
    פרטים נוספיםShow full text description of 11:00 – coffee, tea, and more...»
    11:00 – coffee, tea, and more
    תקצירShow full text abstract about TBA ...»
    TBA
    סימפוזיונים
  • Date:20חמישידצמבר 2018

    Geometric Functional Analysis and Probability Seminar

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    שעה
    13:30 - 15:30
    כותרת
    Stability in the Bakry-Emery theorem
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Max Fathi
    CNRS / Toulouse
    מארגן
    הפקולטה למתמטיקה ומדעי המחשב
    Faculty of Mathematical Sciences Seminar, המחלקה למדעי המחשב ומתמטיקה שימושית
    Faculty of Mathematical Sciences Seminar, המחלקה למתמטיקה
    Faculty of Mathematical Sciences Seminar
    צרו קשר
    פרטים נוספיםShow full text description of The Bakry-Emery theorem asserts that uniformly log-concave p...»
    The Bakry-Emery theorem asserts that uniformly log-concave probability measures satisfy certain functional inequalities, with constants that are better than those associated with the Gaussian measure. In this talk, I will explain how if the constant is almost that of the Gaussian, then the measure almost splits off a Gaussian factor, with explicit quantitative bounds. The proof is based on a combination of Stein's method and simple arguments from calculus of variations. Joint work with Thomas Courtade.
    הרצאה
  • Date:20חמישידצמבר 2018

    TBA

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    שעה
    14:00 - 15:00
    כותרת
    Special Guest Seminar
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצה
    Dr. Naama Geva-Zatorsky
    Technion Integrated Cancer Center; Department of Microbiology & Immunology Faculty of Medicine, Technion, Haifa
    מארגן
    המחלקה לבקרה ביולוגית
    צרו קשר
    הרצאה
  • Date:24שנידצמבר 2018

    Life Science Colloquium

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    שעה
    11:00 - 12:00
    כותרת
    TBD
    מיקום
    אולם ע"ש דולפי ולולה אבנר
    מרצה
    Prof. Paul Taylor
    St. Jude Children's Research Hospital, Memphis
    מארגן
    מדעי החיים
    צרו קשר
    סימפוזיונים
  • Date:24שנידצמבר 2018

    TBA

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    שעה
    14:00 - 15:00
    כותרת
    Special Guest Seminar
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצה
    Dr. Mondira Kundu
    St Jude Children's Research Hospital, Memphis, USA
    מארגן
    המחלקה לבקרה ביולוגית
    צרו קשר
    הרצאה
  • Date:24שנידצמבר 2018

    Foundations of Computer Science Seminar

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    שעה
    14:30 - 16:00
    כותרת
    Towards the Next Generation of Proof Assistants: Enhancing the Proofs–as–Programs Paradigm
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Liron Cohen
    Cornell University
    מארגן
    הפקולטה למתמטיקה ומדעי המחשב
    Faculty of Mathematical Sciences Seminar, המחלקה למדעי המחשב ומתמטיקה שימושית
    Faculty of Mathematical Sciences Seminar, המחלקה למתמטיקה
    Faculty of Mathematical Sciences Seminar
    צרו קשר
    פרטים נוספיםShow full text description of As software has grown increasingly critical to our society&#...»
    As software has grown increasingly critical to our society's infrastructure, mechanically-verified software has grown increasingly important, feasible, and prevalent. Proof assistants have seen tremendous growth in recent years because of their success in the mechanical verification of high-value applications in many areas, including cyber security, cyber-physical systems, operating systems, compilers, and microkernels. These proof assistants are built on top of constructive type theory whose computational interpretation is given by the proofs-as-programs paradigm, which establishes a correspondence between formal proofs and computer programs. However, while both proof theory and programming languages have evolved significantly over the past years, the cross-fertilization of the independent new developments in each of these fields has yet to be explored in the context of this paradigm. This naturally gives rise to the following questions: how can modern notions of computation influence and contribute to formal foundations, and how can modern reasoning techniques improve the way we design and reason about programs?

    In this talk I first demonstrate how using programming principles that go beyond the standard lambda-calculus, namely state and non-determinism, promotes the specification and verification of modern systems, e.g. distributed systems. I then illustrate the surprising fragility of proof assistants in the presence of such new computational capabilities, and outline my ongoing efforts to develop a more robust foundation. For the converse direction, I show how incorporating modern proof-theoretic techniques offers a more congenial framework for reasoning about hard programming problems and hence facilitates the verification effort.
    הרצאה
  • Date:25שלישידצמבר 2018

    To be announced

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    שעה
    10:00 - 11:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    Auditorium
    מרצה
    Dr. Ilana Kolodkin
    Department of Molecular Genetics
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    הרצאה
  • Date:25שלישידצמבר 2018

    Chemical and Biological Physics Special Seminar

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    שעה
    10:45
    כותרת
    Cell-Matrix Interactions in Fibrosis and Cancer: Multiscale mechano-chemical models
    מיקום
    בניין פרלמן למדעי הכימיה
    Room 404
    מרצה
    Prof. Vivek Shenoy
    University of Pennsylvania
    מארגן
    מרכז לפיסיקה ביולוגית עש קלור
    צרו קשר
    תקצירShow full text abstract about Much of our understanding of the biological mechanisms that ...»
    Much of our understanding of the biological mechanisms that underlie cellular functions, such as migration, differentiation and force sensing has been garnered from studying cells cultured on two-dimensional (2D) substrates. In the recent years there has been intense interest and effort to understand cell mechanics in three-dimensional (3D) cultures, which more closely resemble the in vivo microenvironment. However, a major challenge unique to 3D settings is the dynamic feedback between cells and their surroundings. In many 3D matrices, cells remodel and reorient local extracellular microenvironment, which in turn alters the active mechanics and in many cases, the cell phenotype. Most models for matrices to date do not account for such positive feedback. Such models, validated by experiments, can provide a quantitative framework to study how injury related factors (in pathological conditions such as fibrosis and cancer metastasis) alter extracellular matrix (ECM) mechanics. They can also be used to analyze tissue morphology in complex 3D environments such as during morphogenesis and organogenesis, and guide such processes in engineered 3D tissues. In this talk, I will present discrete network simulations to study how cells remodel matrices and how this remodeling can lead to force transmission over large distances in cells. I will also discuss an active tissue model to quantitatively study the influence of mechanical constraints and matrix stiffness on contractility and stability of micropatterned tissues.
    הרצאה
  • Date:25שלישידצמבר 2018

    Algebraic Geometry and Representation Theory Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Symmetries of the hydrogen atom and algebraic families
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Eyal subag
    מארגן
    הפקולטה למתמטיקה ומדעי המחשב
    Faculty of Mathematical Sciences Seminar
    צרו קשר
    הרצאה
  • Date:25שלישידצמבר 2018

    Algebraic Geometry and Representation Theory Seminar

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    שעה
    11:15 - 12:15
    כותרת
    Symmetries of the hydrogen atom and algebraic families
    מיקום
    בניין יעקב זיסקינד
    Room 155
    מרצה
    Eyal Subag
    .
    מארגן
    הפקולטה למתמטיקה ומדעי המחשב
    Faculty of Mathematical Sciences Seminar
    צרו קשר
    פרטים נוספיםShow full text description of The hydrogen atom system is one of the most thoroughly studi...»
    The hydrogen atom system is one of the most thoroughly studied examples of a quantum mechanical system. It can be fully solved, and the main reason why is its (hidden) symmetry. In this talk I shall explain how the symmetries of the Schrödinger equation for the hydrogen atom, both visible and hidden, give rise to an example in the recently developed theory of algebraic families of Harish-Chandra modules. I will show how the algebraic structure of these symmetries completely determines the spectrum of the Schrödinger operator and sheds new light on the quantum nature of the system. No prior knowledge on quantum mechanics will be assumed.
    הרצאה
  • Date:25שלישידצמבר 2018

    Scientific Council meeting

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    שעה
    14:00 - 17:00
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    Kimmel Auditorium
    צרו קשר
    אירועים אקדמיים
  • Date:25שלישידצמבר 2018

    Seminar in Geometry and Topology

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    שעה
    16:00 - 18:00
    כותרת
    Describing Blaschke products by their critical points
    מיקום
    בניין יעקב זיסקינד
    Room 1
    מרצה
    Oleg Ivrii
    Caltech
    מארגן
    הפקולטה למתמטיקה ומדעי המחשב
    Faculty of Mathematical Sciences Seminar
    צרו קשר
    פרטים נוספיםShow full text description of In this talk, I will discuss a question which originates in ...»
    In this talk, I will discuss a question which originates in complex analysis but is really a problem in non-linear elliptic PDE. A finite Blaschke product is a proper holomorphic self-map of the unit disk, just like a polynomial is a proper holomorphic self-map of the complex plane. A celebrated theorem of Heins says that up to post-composition with a M\"obius transformation, a finite Blaschke product is uniquely determined by the set of its critical points. Konstantin Dyakonov suggested that it may interesting to extend this result to infinite degree. However, one must be a little careful since infinite Blaschke products may have identical critical sets. I will show that an infinite Blaschke product is uniquely determined by its "critical structure" and describe all possible critical structures which can occur. By Liouville's correspondence, this question is equivalent to studying nearly-maximal solutions of the Gauss curvature equation $Delta u = e^{2u}$. This problem can then be solved using PDE techniques, using the method of sub- and super-solutions.
    הרצאה
  • Date:26רביעידצמבר 2018

    Developmental Club Series 2018-2019

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    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצה
    Prof. Eldad Tzahor
    מארגן
    המחלקה לגנטיקה מולקולרית
    Developmental Club
    צרו קשר
    הרצאה
  • Date:26רביעידצמבר 2018

    Developmental Club Series 2018-19

    More information
    שעה
    10:00
    כותרת
    Heart Repair and Regeneration
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצה
    Eldad Tzahor
    מארגן
    המחלקה לגנטיקה מולקולרית
    Developmental Club
    צרו קשר
    הרצאה

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