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May 07, 2014

  • Date:13WednesdayAugust 2014

    The Nancy & Stephen Grand Israel National Center for Personalized Medicine - guest lecture - The molecular motor of the Sarcomere / The Fauna, A New View on Theory of Muscle Dynamics, Clinical Implications and Clinical Applications

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    Time
    14:15 - 15:45
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerProf. Amir Landesberg
    Faculty of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel
    Organizer
    Department of Biomolecular Sciences
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    Lecture
  • Date:15FridayAugust 2014

    Friday Culture: Following the Little Prince- Dr. Haim Shapira

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    Time
    11:00 - 11:00
    Location
    Dolfi and Lola Ebner Auditorium
    Contact
    Cultural Events
  • Date:20WednesdayAugust 2014

    Multiscale simulations of colloidal nanostructures: self-assembly, ligand activity and molecular delivery

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    Time
    11:00 - 12:00
    Title
    Joint Seminar: Organic Chemistry & Chemical Physics
    Location
    Perlman Chemical Sciences Building
    LecturerProf. Petr Kral
    University of Illinois Chicago
    Organizer
    Department of Molecular Chemistry and Materials Science
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    Lecture
  • Date:27WednesdayAugust 2014

    "Waiting for Joseph"- water management

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    Time
    11:00 - 11:00
    Location
    Perlman Chemical Sciences Building
    LecturerProf. Micha Tomkiewicz
    Department of Physics, Brooklyn College of CUNY
    Organizer
    Department of Molecular Chemistry and Materials Science
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    Lecture
  • Date:28ThursdayAugust 2014

    Two-sided radial SLE and length-biased chordal SLE

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    Time
    11:00 - 11:00
    Location
    Jacob Ziskind Building
    LecturerLaurie Field
    University of Chicago
    Organizer
    Faculty of Mathematics and Computer Science
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    Lecture
  • Date:31SundayAugust 2014

    Using Polymer Surface Confinement To Engineer Substrates for for Adult Stem Cell Differentiation

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    Time
    11:00 - 11:00
    Location
    Perlman Chemical Sciences Building
    LecturerProf. Miriam Rafailovich
    Department of Materials Science- co-Director Program in Chemical and Molecular Engineering SUNY at Stony Brook
    Organizer
    Department of Molecular Chemistry and Materials Science
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    Lecture
  • Date:02TuesdaySeptember 2014

    "Ménage-à-trois: Single-atom Catalysis, Mass Spectrometry, and Computational Chemistry"

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    Time
    11:00 - 12:00
    Title
    Joint Seminar:Organic Chemistry & Materials and Interfaces
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Dr. Helmut Schwarz
    Technische Universität Berlin
    Organizer
    Department of Molecular Chemistry and Materials Science
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    Lecture
  • Date:04ThursdaySeptember 2014

    Cellulose: a fascinating material with a promising future

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    Time
    13:00 - 13:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Theo van de Ven
    Sir William Mcdonald Chair in Chemistry, McGill University, Montreal, Canada
    Organizer
    Weizmann School of Science
    Contact
    AbstractShow full text abstract about Research in cellulose is exploding exponentially, as researc...»
    Research in cellulose is exploding exponentially, as researchers look for renewable resources to replace chemicals and materials derived from fossil fuels. Cellulose is the most abundant biopolymer on earth and can be modified to make a large number of useful products, several of which will be discussed. Cellulose can be made into superabsorbent papers and gels, by introducing the appropriate amount of charge groups, usually carboxyl groups. Carboxylated fibers swell and can take up water more than hundred times their weight. They can be modified into an aqueous dope, from which one can spin textile fibers. The morphology of swollen fibers depends on the way the charges are introduced and reveals the underlying structure of the cell wall. By increasing the charge above 3 meq/g, the fibers break apart in nanocellulose and dissolved carboxylated cellulose (DCC). The nancellulose consist of cellulose nanofibers (CNF) and cellulose nanocrystals (CNC). The larger the charge, the larger the fraction of CNC. This CNC is different from conventional CNC, made by acid hydrolysis of cellulose fibers: it has DCC chains protruding from each end, which entangle when making films, resulting in transparent films much stronger than made from conventional CNC. They also have different cytotoxic properties: the higher the charge, the more they affect the metabolism of certain cells. The DCC end chains of CNC can by removed by hydrolysis, resulting in CNC with negatively charged ends. These particles can be crosslinked to make much longer chains, resembling CNF. Carboxyl groups in cellulose can be readily transformed in other functional groups, e.g. by a bioconjugation reaction. CNC films can be made superhydrophobic and paper can be made functional, making it hydrophobic, fluorescent or introducing sensors that can detect pathogens.
    Lecture
  • Date:04ThursdaySeptember 2014

    Cholinergic interneurons and state correlates in dorsomedial and dorsolateral striatum

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    Time
    14:00 - 14:00
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerProf. Geoffrey Schoenbaum, MD,PhD
    Branch Chief, National Institute on Drug Abuse, NIH
    Organizer
    Department of Brain Sciences
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    Lecture
  • Date:07SundaySeptember 2014

    Relapse to drug use: behavioral and neuronal mechanisms

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    Time
    12:30 - 12:30
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerProf. Yavin Shaham
    Branch Chief, Behavioral Neuroscience Branch, Intramural Research Program, NIDA-NIH
    Organizer
    Department of Brain Sciences
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    Lecture
  • Date:08MondaySeptember 2014

    Balanced Allocations: A Simple(r) Proof for the Heavily Loaded Case

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    Time
    14:30 - 14:30
    Location
    Jacob Ziskind Building
    LecturerUdi Wieder
    Microsoft Research Silicon Valley
    Organizer
    Faculty of Mathematics and Computer Science
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    Lecture
  • Date:11ThursdaySeptember 2014

    Magnetic Resonance Seminar

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    Time
    09:30 - 09:30
    Title
    Magic Angle Spinning NMR Spectroscopy of Protein Assemblies
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Tatyana Polenova
    University of Delaware
    Organizer
    Department of Chemical and Biological Physics
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    Lecture
  • Date:12FridaySeptember 2014

    Friday Culture:Thoughts at night- Dr Haim Shapira

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    Time
    11:00 - 11:00
    Location
    Dolfi and Lola Ebner Auditorium
    Contact
    Cultural Events
  • Date:12FridaySeptember 2014

    About Miracles and Wonders

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    Time
    13:00 - 13:00
    Title
    Children's Theater
    Location
    Michael Sela Auditorium
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    Cultural Events
  • Date:13SaturdaySeptember 2014

    Eli And Mariano

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    Time
    21:00 - 21:00
    Title
    Standup
    Location
    Michael Sela Auditorium
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    Cultural Events
  • Date:15MondaySeptember 2014

    The Lover

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    Time
    20:30 - 20:30
    Title
    Habima Theatre
    Location
    Michael Sela Auditorium
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    Cultural Events
  • Date:16TuesdaySeptember 2014

    Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development

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    Time
    14:00 - 14:00
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerDr. Vladimir Teif
    German Cancer Research Center (DKFZ)
    Organizer
    Department of Physics of Complex Systems
    Contact
    AbstractShow full text abstract about During differentiation of embryonic stem cells, chromatin re...»
    During differentiation of embryonic stem cells, chromatin reorganizes to establish cell type specific expression programs. Here, we have dissected the linkages between DNA methylation (5mC), hydroxymethylation (5hmC), nucleosome repositioning and binding of the transcription factor CTCF during this process. By integrating MNase-seq and ChIP-seq experiments in mouse embryonic stem cells (ESC) and their differentiated counterparts with biophysical modeling, we found that the interplay between these factors depends on their genomic context. The mostly unmethylated CpG islands have reduced nucleosome occupancy and are enriched in cell type-independent binding sites for CTCF. The few remaining methylated CpG dinucleotides are preferentially associated with nucleosomes. In contrast, outside of CpG islands most CpGs are methylated and the average methylation density oscillates so that it is highest in the linker region between nucleosomes. Outside CpG islands binding of TET1, an enzyme that converts 5mC to 5hmC, is associated with labile, MNase-sensitive nucleosomes. Such nucleosomes are poised for eviction in ESCs and become stably bound in differentiated cells where the TET1 and 5hmC levels go down. This process regulates a class of CTCF binding sites outside CpG islands that are occupied by CTCF in ESCs but loose the protein during differentiation. We rationalize this cell type dependent targeting of CTCF with a quantitative biophysical model of competitive binding with the histone octamer in dependence of the TET1, 5hmC and 5mC state.

    Journal reference: http://genome.cshlp.org/content/early/2014/05/08/gr.164418.113

    DKFZ press release: http://www.dkfz.de/en/presse/pressemitteilungen/2014/dkfz-pm-14-37-The-Long-and-Winding-Road-to-Gene-Regulation.php

    Lecture
  • Date:16TuesdaySeptember 2014

    Isolated hypersurface singularities and associated forms

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    Time
    16:00 - 16:00
    Location
    Jacob Ziskind Building
    LecturerAlex Isaev
    Australian National University
    Organizer
    Faculty of Mathematics and Computer Science
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    Lecture
  • Date:16TuesdaySeptember 2014

    Machnisei Rachamim

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    Time
    21:00 - 21:00
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:17WednesdaySeptember 2014

    CRS your toolbox to sucssses - Mini Symposium of The Department of Chemical Resarch Support

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    Time
    09:00 - 13:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Organizer
    Department of Chemical Research Support
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    Contact
    Lecture

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