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June 01, 2014
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Date:20SundayJuly 2014Lecture
"How drugs bind and modulate their receptors: revealing the structural basis of GPCR signaling through simulation"
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Ron Dror
Stanford UniversityOrganizer Department of Chemical and Structural BiologyContact -
Date:24ThursdayJuly 2014Lecture
Quenched invariance principle for simple random walk on clusters in correlated percolation models.
More information Time 11:05 - 11:05Location Jacob Ziskind BuildingLecturer Eviatar Procaccia
Organizer Faculty of Mathematics and Computer ScienceContact -
Date:27SundayJuly 201429TuesdayJuly 2014Conference
Medical Research at the Cutting Edge
More information Time All dayLocation IrelandChairperson Rachel ValdmanHomepage Contact -
Date:29TuesdayJuly 2014Lecture
MCB Seminar - Rand Arafeh
More information Time 12:15 - 13:15Title Identification and Characterization of Rasa2 as a Tumor Suppressor Gene in MelanomaLocation Wolfson Building for Biological ResearchLecturer Rand Arafeh
Organizer Department of Molecular Cell BiologyContact -
Date:29TuesdayJuly 2014Lecture
MCB Seminar - Michal Levo
More information Time 12:15 - 13:15Title To bind or not to bind? Characterizing DNA binding by regulatory proteins, both in-vitro and within a single cellLocation Wolfson Building for Biological ResearchLecturer Michal Levo Organizer Department of Molecular Cell BiologyContact -
Date:03SundayAugust 2014Lecture
Lateral and Normal Adhesion Forces at the Interface between a Liquid Drop and a Substrate
More information Time 11:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Rafael Tadmor
Lamar University, TX, USAOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:04MondayAugust 2014Lecture
Insights into how resistance caqn arise to Hsp90 Inhibitor Drugs
More information Time 14:00 - 14:00Location Max and Lillian Candiotty BuildingLecturer Prof. Peter Piper
Univ. of Sheffield, U.K.Organizer Department of Immunology and Regenerative BiologyContact -
Date:05TuesdayAugust 2014Lecture
Jacobi identity and intersection of triangle altitudes in non-Euclidean geometry
More information Time 16:00 - 16:00Location Jacob Ziskind BuildingLecturer Victor Prasolov
Independent University of MoscowOrganizer Faculty of Mathematics and Computer ScienceContact -
Date:06WednesdayAugust 2014Lecture
Linking dynamics of neural activity to movement and decisions
More information Time 12:30 - 12:30Location Nella and Leon Benoziyo Building for Brain ResearchLecturer Dr. Mati Joshua
Dept of Neurobiology Duke University, Durham, NC, USAOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Neurons continuously modulate their activity in time and mag...» Neurons continuously modulate their activity in time and magnitude; it is unclear how the dynamics of activity is related to brain computations and to behavior. In the first part of my talk I will show how we link between the dynamics of activity and the computation in the cerebellum-brainstem circuitry that generates eye movement. We found that dynamics of responses of neurons support a hierarchical organization of a neural integrator. In the second part of my talk I will show how we use the smooth pursuit eye movement to continuously readout the decision process. I will present a new framework for studying the neural mechanisms for decisions. -
Date:12TuesdayAugust 2014Lecture
Unraveling principles of cap-independent translation in human genes and viruses using thousands of designed regulatory sequences
More information Time 12:15 - 12:15Location Wolfson Building for Biological ResearchLecturer Shira Weingarten-Gabbay. Organizer Department of Molecular Cell BiologyContact -
Date:12TuesdayAugust 2014Lecture
Mitochondria as a Pharmacological Target For Eliminating Senescent Cells
More information Time 12:15 - 12:15Location Wolfson Building for Biological ResearchLecturer Dominick Burton Organizer Department of Molecular Cell BiologyContact -
Date:13WednesdayAugust 2014Lecture
Spiking patterns and cortical neuron detectability
More information Time 11:00 - 11:00Location Nella and Leon Benoziyo Building for Brain ResearchLecturer Guy Doron, PhD
Postdoc Prof. Matthew Larkum Lab Humboldt University of BerlinOrganizer Department of Brain SciencesContact Abstract Show full text abstract about In recent years, substantial advances have been made towards...» In recent years, substantial advances have been made towards directly linking single-cell activity and sensation. While it was shown that the activity of single cortical neurons can evoke measurable sensory effects, the relation between the regularity, frequency and number of action potentials (APs) to the evoked sensations is unknown and it is still unclear, how these effects depend on cell type and the precise discharge pattern. In a previous study we used nanostimulation, a technique that allows in vivo manipulation of spike activity and identification of individual neurons (Houweling et al., 2010), to provide evidence that individual neurons in the rat barrel cortex can have an impact on behavioral responses in a detection task. In this talk I will discuss the effects of spike train irregularity, frequency and number on the detectability of single-neuron stimulation in rat somatosensory cortex. Our data imply that the behaving animal is sensitive to single neurons' spikes and even to their temporal patterning. -
Date:13WednesdayAugust 2014Lecture
The Nancy & Stephen Grand Israel National Center for Personalized Medicine - guest lecture - The molecular motor of the Sarcomere / The Fauna, A New View on Theory of Muscle Dynamics, Clinical Implications and Clinical Applications
More information Time 14:15 - 15:45Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Amir Landesberg
Faculty of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, IsraelOrganizer Department of Biomolecular SciencesContact -
Date:15FridayAugust 2014Cultural Events
Friday Culture: Following the Little Prince- Dr. Haim Shapira
More information Time 11:00 - 11:00Location Dolfi and Lola Ebner AuditoriumContact -
Date:20WednesdayAugust 2014Lecture
Multiscale simulations of colloidal nanostructures: self-assembly, ligand activity and molecular delivery
More information Time 11:00 - 12:00Title Joint Seminar: Organic Chemistry & Chemical PhysicsLocation Perlman Chemical Sciences BuildingLecturer Prof. Petr Kral
University of Illinois ChicagoOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:27WednesdayAugust 2014Lecture
"Waiting for Joseph"- water management
More information Time 11:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Micha Tomkiewicz
Department of Physics, Brooklyn College of CUNYOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:28ThursdayAugust 2014Lecture
Two-sided radial SLE and length-biased chordal SLE
More information Time 11:00 - 11:00Location Jacob Ziskind BuildingLecturer Laurie Field
University of ChicagoOrganizer Faculty of Mathematics and Computer ScienceContact -
Date:31SundayAugust 2014Lecture
Using Polymer Surface Confinement To Engineer Substrates for for Adult Stem Cell Differentiation
More information Time 11:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Miriam Rafailovich
Department of Materials Science- co-Director Program in Chemical and Molecular Engineering SUNY at Stony BrookOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:02TuesdaySeptember 2014Lecture
"Ménage-à-trois: Single-atom Catalysis, Mass Spectrometry, and Computational Chemistry"
More information Time 11:00 - 12:00Title Joint Seminar:Organic Chemistry & Materials and InterfacesLocation Gerhard M.J. Schmidt Lecture HallLecturer Prof. Dr. Helmut Schwarz
Technische Universität BerlinOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:04ThursdaySeptember 2014Lecture
Cellulose: a fascinating material with a promising future
More information Time 13:00 - 13:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Theo van de Ven
Sir William Mcdonald Chair in Chemistry, McGill University, Montreal, CanadaOrganizer Weizmann School of ScienceContact Abstract Show full text abstract about Research in cellulose is exploding exponentially, as researc...» Research in cellulose is exploding exponentially, as researchers look for renewable resources to replace chemicals and materials derived from fossil fuels. Cellulose is the most abundant biopolymer on earth and can be modified to make a large number of useful products, several of which will be discussed. Cellulose can be made into superabsorbent papers and gels, by introducing the appropriate amount of charge groups, usually carboxyl groups. Carboxylated fibers swell and can take up water more than hundred times their weight. They can be modified into an aqueous dope, from which one can spin textile fibers. The morphology of swollen fibers depends on the way the charges are introduced and reveals the underlying structure of the cell wall. By increasing the charge above 3 meq/g, the fibers break apart in nanocellulose and dissolved carboxylated cellulose (DCC). The nancellulose consist of cellulose nanofibers (CNF) and cellulose nanocrystals (CNC). The larger the charge, the larger the fraction of CNC. This CNC is different from conventional CNC, made by acid hydrolysis of cellulose fibers: it has DCC chains protruding from each end, which entangle when making films, resulting in transparent films much stronger than made from conventional CNC. They also have different cytotoxic properties: the higher the charge, the more they affect the metabolism of certain cells. The DCC end chains of CNC can by removed by hydrolysis, resulting in CNC with negatively charged ends. These particles can be crosslinked to make much longer chains, resembling CNF. Carboxyl groups in cellulose can be readily transformed in other functional groups, e.g. by a bioconjugation reaction. CNC films can be made superhydrophobic and paper can be made functional, making it hydrophobic, fluorescent or introducing sensors that can detect pathogens.
