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April 28, 2015
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Date:28TuesdayApril 2015Lecture
TBA
More information Time 10:30 - 10:30Location Neve ShalomLecturer BARTUMEU FIOL
UNIVERSITY OF BARCELONAOrganizer Department of Particle Physics and AstrophysicsContact -
Date:28TuesdayApril 2015Lecture
Challenges in carotenoid biosynthesis research: From metabolism to genetic regulation
More information Time 11:15 - 11:15Location Ullmann Building of Life SciencesLecturer Prof. Joseph Hirschberg
Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, JerusalemOrganizer Department of Plant and Environmental SciencesContact -
Date:28TuesdayApril 2015Lecture
NELSON BRAGA
More information Time 12:00 - 12:00Location Neve ShalomLecturer NELSON BRAGA
FEDERAL UNIVERSITY OF RIO DE JANERIO, BRAZILOrganizer Department of Particle Physics and AstrophysicsContact Abstract Show full text abstract about It is by now well known that the AdS/CFT duality provides an...» It is by now well known that the AdS/CFT duality provides an interesting way of calculating anomalous dimensions at high spin, for a gauge theory at strong coupling. A high spin operator, made of adjoint fields, is represented by (or dual to) a rotating open string in anti-de Sitter space. The anomalous dimension shows up, in the string side of the correspondence, simply as the difference between string energy and spin. On the other hand it is also know that it is possible to introduce matter degrees of freedom - fields in the fundamental representation of the gauge group - in the AdS/CFT duality by introducing probe (flavour) branes. This approach leads to a nice description of meson states. So, a natural question to be asked is : can one calculate the anomalous dimension for operators in the fundamental representation, like a quark anti-quark, using AdS/CFT? This question will be the main issue of this seminar. We will see that the presence of an energy scale makes it a non trivial task the identification of a quantity representing, in the string side, the dimension of the gauge theory operator. Serching for the solution to this problem, we found a new entry in the dictionary of AdS/CFT: the anomalous dimension at high spin is proportional to the string proper length. Also, we found strong indications that, in the case of a non conformal duality, the operator properties are obtained from measurements made by a local observer (not sensible to energy scales) in the anti-de Sitter space, while the description of the states comes from a coordinate time observer. (reference: JHEP 1408, 104 (2014) at ArXiv:1405.7388) -
Date:28TuesdayApril 2015Lecture
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Amit Zeisel
Division of Molecular Neurobiology, Dept of Medical Biochemistry and Biophysics Karolinska Institutet, Stockholm, SwedenOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The mammalian cerebral cortex supports cognitive functions s...» The mammalian cerebral cortex supports cognitive functions such as sensorimotor integration, memory, and social behaviors. Normal brain function relies on a diverse set of differentiated cell types, including neurons, glia, and vasculature. Here, we have used large-scale single-cell RNA sequencing (RNA-seq) to classify cells in the mouse somatosensory cortex and hippocampal CA1 region. We found 47 molecularly distinct subclasses, comprising all known major cell types in the cortex. We identified numerous marker genes, which allowed alignment with known cell types, morphology, and location. -
Date:28TuesdayApril 2015Lecture
New Insights into the Transport Mechanism of the Neurotransmitter:Sodium Symporter Family
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Dr. Lina Malinauskaite
University of OxfordOrganizer Department of Chemical and Structural BiologyContact -
Date:28TuesdayApril 2015Cultural Events
Music at noon - Beatles tribute concert
More information Time 16:30 - 17:30Location Michael Sela AuditoriumContact -
Date:29WednesdayApril 2015Lecture
Cell competition and Tumorigenesis
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Gines Morata
Centro de Biología Molecular, CSIC-UAM, Universidad Autónoma de Madrid, SpainContact -
Date:29WednesdayApril 2015Lecture
Turbulent Magnetic Field Amplification in Young Galaxies
More information Time 10:15 - 11:15Location Dannie N. Heineman LaboratoryLecturer Jennifer Schober Organizer Nella and Leon Benoziyo Center for AstrophysicsContact Abstract Show full text abstract about Magnetic fields play an important role in present-day galaxi...» Magnetic fields play an important role in present-day galaxies, for instance by influencing the star formation process. In models of young galaxies magnetic fields are usually not considered as they were assumed not to be dynamical important at high redshifts. In the presence of turbulence, however, the small-scale or turbulent dynamo can amplify weak magnetic seed fields by randomly stretching, twisting, and folding the field lines. The details of this process depend on the nature of turbulence, i.e. on the hydrodynamic and magnetic Reynolds numbers, and on the compressibility of the gas. In my talk I will introduce the basics of the turbulent dynamo and sketch our recent progress in describing it analytically and numerically. With a model of a typical young galaxy, where turbulence is driven by accretion and by supernova explosions, we determine the growth rate of the small-scale dynamo. We follow the exponential growth of the magnetic field on the viscous scale and also the subsequent transport of the magnetic energy to larger scales in the non-linear dynamo phase. Depending on the parameters of our model we find that equipartition of magnetic and kinetic energy, which corresponds to a field strength of roughly 10^(-5) G, is reached within 4 to 270 Myr. Thus, we expect that the turbulent dynamo can generate strong unordered fields already in very young galaxies which should be considered in future models of galaxy evolution. -
Date:29WednesdayApril 2015Colloquia
Special Chemistry Colloquium - "Bond, Chemical Bond"
More information Time 11:00 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Wilson Ho
Department of Physics and Astronomy, University of California/USAOrganizer Faculty of ChemistryContact -
Date:29WednesdayApril 2015Lecture
Deviation from identity of macroscopic properties of enantiomers –via water chiral preference. (Is water chiral?)
More information Time 14:00 - 14:00Location Perlman Chemical Sciences BuildingLecturer Dr. Yosef Scolnik
IYAR (Israel Institute for Advanced Research). Weizmann InstituteOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:29WednesdayApril 2015Lecture
Investigations of Implosions on the National Ignition Facility and discussion on the fusion yield from NIF
More information Time 15:15 - 15:15Location Edna and K.B. Weissman Building of Physical SciencesLecturer H. A. Scott, B. A. Hammel
Lawrence Livermore National Laboratory, Livermore, CA USAOrganizer Department of Particle Physics and AstrophysicsContact Abstract Show full text abstract about Hydrodynamic instabilities are a primary impediment to the s...» Hydrodynamic instabilities are a primary impediment to the success of inertial confinement fusion (ICF), as they can severely degrade capsule performance [1]. Even with perfectly smooth capsules, the fill tube and capsule support provide perturbations that seed instabilities. Consequently,
understanding the evolution of perturbations and their effects on capsule performance is critical to the success of an ICF program. We discuss here the use of spectroscopic methods to diagnose the growth of hydrodynamic instabilities in imploding capsules. To understand capsule evolution and guide experimental design and interpretation, we use high-resolution HYDRA [2] simulations, postprocessed with Cretin [3], to simulate the spectra produced by capsules with specified initial perturbations. The
spectral simulations cover a wide range of conditions, from the multi-keV hot spot to the cold dense pusher.
For capsules with mid-Z dopants, the resulting X-ray spectrum can be analyzed to obtain information about the plasma conditions. An analysis of the dopant K-shell line emission has been used to estimate the mass of ablator material mixed into the hot spot [4]. Other spectral features can be used to provide information about the shell and further constrain the mixed mass. Other recent work has focused on using spectroscopy to quantitatively characterize the growth of perturbations. Capsules containing a small amount of argon in the gas produce sufficient emission before peak compression to provide radiographic information. The analysis of simulated spectra from capsules with machined perturbations demonstrates the possibility of extracting quantitative measures of perturbation growth.
References
[1] B.A. Hammel, et al, High Energy Density Physics, 6 (2010) 171.
[2] M. Marinak, et al, Phys. Plasmas 8 (2001) 2275.
[3] H.A. Scott, J Quant Spectrosc Radiat Transfer 71 (2001) 681.
[4] S.P. Regan et al. Phys. Rev, Lett. 111, 045001 (2013).
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Date:30ThursdayApril 2015Lecture
Nanobots: vesicle-templates assembly and applications of functional nanocapsules
More information Time 11:00 - 12:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof Eugene Pinkhassik Organizer Department of Molecular Chemistry and Materials ScienceContact -
Date:30ThursdayApril 2015Lecture
'Cellular Origin and Functional Specialization of Tissue-resident Macrophages
More information Time 11:00 - 12:00Location Wolfson Building for Biological ResearchLecturer Dr. Martin Guilliams Organizer Department of Systems ImmunologyContact -
Date:30ThursdayApril 2015Colloquia
Spotting the elusive Majorana under the microscope
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Ali Yazdani
PrincetonOrganizer Faculty of PhysicsContact Abstract Show full text abstract about Topological superconductors are a distinct form of matter th...» Topological superconductors are a distinct form of matter that is predicted to host boundary Majorana fermions. These quasi-particles are the emergent condensed matter analogs of the putative elementary spin-1/2 particles originally proposed by Ettore Majorana with the intriguing property of being their own anti-particles. The search for Majorana quasi-particles in condensed matter systems is motivated in part by their potential use as topological qubits to perform fault-tolerant computation aided by their non-Abelian characteristics. Recently, we have proposed a new platform for the realization of Majorana fermions in condensed matter, based on chains of magnetic atoms on the surface of a superconductor. This platform lends itself to measurements with the scanning tunneling microscope (STM) that can be used to directly visualize the Majorana edge modes with both high energy and spatial resolution. Using rather unique STM instrumentation, we have succeeded in creating this platform and have observed the predicted signatures of localized Majorana edge modes. I will describe our Majorana platform, the experiments to date, and the outlook for further experiments on Majorana fermions in condensed matter systems. -
Date:30ThursdayApril 2015Lecture
Demystifying publication process at Nature Neuroscience
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Min Cho, PhD, Senior Editor
Nature Neuroscience, Nature Publishing GroupOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Scientific publishing is a natural part of the research ende...» Scientific publishing is a natural part of the research endeavor as it marks the end of one project and the start of another. Even so, the actual publication process spanning from manuscript submission, initial editorial evaluation, peer-review and the journal’s decision to publish a given manuscript may appear mysterious from the author’s perspective. In high profile, high impact journals where the published manuscripts are given exposure to the widest audience possible, the manuscript selection process can be especially arduous and competitive at times. This presentation will discuss the general issues and framework of publishing in high profile scientific journals, and will explain the editorial process and manuscript selection in Nature Neuroscience. Also included in the discussion are suggestions for efficient writing of scientific manuscripts and rebuttal letters, potential utility of presubmission inquiry, and transference of manuscripts and reviews from one journal to another in Nature Publishing Group’s portfolio and beyond. -
Date:30ThursdayApril 2015Lecture
From near and far- cancer-associated fibroblasts mediate inflammation during breast cancer progression and metastasis
More information Time 14:00 - 15:00Title Guest SeminarLocation Wolfson Building for Biological ResearchLecturer Dr. Neta Erez
Department of Pathology Sackler School of Medicine Tel Aviv UniversityOrganizer Department of Systems ImmunologyContact -
Date:30ThursdayApril 2015Lecture
Prof. Sima Lev - Life Science Lecture
More information Time 15:00 - 16:00Title Epithelial-Mesenchymal Transition (EMT), combination therapy and drug resistance in Triple Negative Breast Cancer (TNBC)Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Sima Lev
Department of Molecular Cell BiologyContact -
Date:01FridayMay 2015Lecture
Novel coupled cluster approaches for weak and strong correlations
More information Time 10:00 - 10:00Location Perlman Chemical Sciences BuildingLecturer Prof. Gustavo Scuseria
Dept. of Chemistry, Rice UniversityOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:03SundayMay 201504MondayMay 2015Conference
Stress, PTSD and Psychiatric Disorders: From Basic Science to Theraputic Intervention
More information Time 08:00 - 19:00Location The David Lopatie Conference CentreHomepage -
Date:03SundayMay 2015Lecture
Molecular Mechanisms ofTranscription in the Third Domain – from molecules to systems
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Finn Werner
Structural and Molecular Biology, University College London, London, UKOrganizer Department of Molecular GeneticsContact Abstract Show full text abstract about Our laboratory is applying an interdisciplinary and multi sc...» Our laboratory is applying an interdisciplinary and multi scalar approach to characterise the molecular mechanisms of transcription and in particular of multisubunit RNA polymerases (RNAPs). We explore model systems from the third domain of life, the Archaea, not only because they are fascinating organisms in their own right but because their transcription apparatus is a model system for – and more biochemically tractable than - eukaryotic RNAPII. Today I will present progress in our understanding of (i) the architecture of transcription initiation complexes, (ii) conformational dynamics of RNAP during the transcription cycle, and (iii) the whole genome-distribution of the basal transcription apparatus and transcription start site mapping. This analysis reveals the underlying molecular nature of the spontaneous DNA melting in archaea, which requires ATP hydrolysis in the RNAPII system. Our data furthermore show that the dynamic recruitment and release of basal factors that guide RNAP through the transcription cycle is modulated by the coupling of transcription and translation, of RNAPs and ribosomes.
