Pages

April 01, 2015

  • Date:29WednesdayApril 2015

    Deviation from identity of macroscopic properties of enantiomers –via water chiral preference. (Is water chiral?)

    More information
    Time
    14:00
    Location
    Perlman Chemical Sciences Building
    Room 404
    Lecturer
    Dr. Yosef Scolnik
    IYAR (Israel Institute for Advanced Research). Weizmann Institute
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    DetailsShow full text description of Abstract Mirror-image asymmetric molecules, i.e. enantiomer...»
    Abstract
    Mirror-image asymmetric molecules, i.e. enantiomers, are classically considered as chemically identical. Parity violation by the nuclear weak force induces a tiny energy difference between chiral isomers. Upon combination with a massive amplification process, expansion of this difference to a detectable macroscopic level may be achieved. In our studies we have prove this in several systems: Stearoylserine "quasi peptide" formation
    Solubility and cluster formation of Alanine
    Peptide Transitions to alpha –helix, shortly described hereafter and others
    We compared structural and dynamic features of synthetic D- and L-polyglutamic acid and polylysine molecules each of 24 identical residues. The helix and random coil configurations and their transition were determined in this study by circular dichroism (CD) and isothermal titration calorimetry (ITC) in water and deuterium oxide. Distinct differences in structure and transition energies between the enantiomer polypeptides were detected by both CD and ITC when dissolved in water. Intriguingly, these differences were by and large abolished in deuterium oxide. Our findings suggest that deviation from physical invariance between the D- and L-polyamino acids is induced in part by different hydration in water which is eliminated in deuterium oxide. We suggest that ortho-H2O, which constitutes 75% of bulk H2O, has a preferential affinity to L-enantiomers.In other words, these studies, prove that indeed water has chiral preferences, Accordingly, Heavy Water has no chiral preference. Differential hydration of enantiomers may have played a role in the selection of L-amino acids by early forms of life.

    Lecture
  • Date:29WednesdayApril 2015

    Investigations of Implosions on the National Ignition Facility and discussion on the fusion yield from NIF

    More information
    Time
    15:15
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    H. A. Scott, B. A. Hammel
    Lawrence Livermore National Laboratory, Livermore, CA USA
    Organizer
    Department of Particle Physics and Astrophysics
    Plasma Seminar
    Contact
    DetailsShow full text description of 15:00 – Light refreshments ...»
    15:00 – Light refreshments
    AbstractShow full text abstract about Hydrodynamic instabilities are a primary impediment to the s...»
    Hydrodynamic instabilities are a primary impediment to the success of inertial confinement fusion (ICF), as they can severely degrade capsule performance [1]. Even with perfectly smooth capsules, the fill tube and capsule support provide perturbations that seed instabilities. Consequently,
    understanding the evolution of perturbations and their effects on capsule performance is critical to the success of an ICF program. We discuss here the use of spectroscopic methods to diagnose the growth of hydrodynamic instabilities in imploding capsules. To understand capsule evolution and guide experimental design and interpretation, we use high-resolution HYDRA [2] simulations, postprocessed with Cretin [3], to simulate the spectra produced by capsules with specified initial perturbations. The
    spectral simulations cover a wide range of conditions, from the multi-keV hot spot to the cold dense pusher.

    For capsules with mid-Z dopants, the resulting X-ray spectrum can be analyzed to obtain information about the plasma conditions. An analysis of the dopant K-shell line emission has been used to estimate the mass of ablator material mixed into the hot spot [4]. Other spectral features can be used to provide information about the shell and further constrain the mixed mass. Other recent work has focused on using spectroscopy to quantitatively characterize the growth of perturbations. Capsules containing a small amount of argon in the gas produce sufficient emission before peak compression to provide radiographic information. The analysis of simulated spectra from capsules with machined perturbations demonstrates the possibility of extracting quantitative measures of perturbation growth.
    References
    [1] B.A. Hammel, et al, High Energy Density Physics, 6 (2010) 171.
    [2] M. Marinak, et al, Phys. Plasmas 8 (2001) 2275.
    [3] H.A. Scott, J Quant Spectrosc Radiat Transfer 71 (2001) 681.
    [4] S.P. Regan et al. Phys. Rev, Lett. 111, 045001 (2013).
    Lecture
  • Date:30ThursdayApril 2015

    Nanobots: vesicle-templates assembly and applications of functional nanocapsules

    More information
    Time
    11:00 - 12:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof Eugene Pinkhassik
    Organizer
    Department of Molecular Chemistry and Materials Science
    Special Seminar
    Contact
    Lecture
  • Date:30ThursdayApril 2015

    'Cellular Origin and Functional Specialization of Tissue-resident Macrophages

    More information
    Time
    11:00 - 12:00
    Location
    Wolfson Building for Biological Research
    Auditorium
    Lecturer
    Dr. Martin Guilliams
    Organizer
    Department of Systems Immunology
    Contact
    Lecture
  • Date:30ThursdayApril 2015

    Spotting the elusive Majorana under the microscope

    More information
    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Lecturer
    Ali Yazdani
    Princeton
    Organizer
    Faculty of Physics
    Contact
    DetailsShow full text description of 11:00 – coffee, tea, and more...»
    11:00 – coffee, tea, and more
    AbstractShow full text abstract about Topological superconductors are a distinct form of matter th...»
    Topological superconductors are a distinct form of matter that is predicted to host boundary Majorana fermions. These quasi-particles are the emergent condensed matter analogs of the putative elementary spin-1/2 particles originally proposed by Ettore Majorana with the intriguing property of being their own anti-particles. The search for Majorana quasi-particles in condensed matter systems is motivated in part by their potential use as topological qubits to perform fault-tolerant computation aided by their non-Abelian characteristics. Recently, we have proposed a new platform for the realization of Majorana fermions in condensed matter, based on chains of magnetic atoms on the surface of a superconductor. This platform lends itself to measurements with the scanning tunneling microscope (STM) that can be used to directly visualize the Majorana edge modes with both high energy and spatial resolution. Using rather unique STM instrumentation, we have succeeded in creating this platform and have observed the predicted signatures of localized Majorana edge modes. I will describe our Majorana platform, the experiments to date, and the outlook for further experiments on Majorana fermions in condensed matter systems.
    Colloquia
  • Date:30ThursdayApril 2015

    Demystifying publication process at Nature Neuroscience

    More information
    Time
    12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Min Cho, PhD, Senior Editor
    Nature Neuroscience, Nature Publishing Group
    Organizer
    Department of Brain Sciences
    Contact
    DetailsShow full text description of Speaker Biography: Min Cho, Ph.D. is a senior editor of Nat...»
    Speaker Biography:
    Min Cho, Ph.D. is a senior editor of Nature Neuroscience where he manages the selection of original research manuscripts for publication. He received his doctorate degree in molecular biology and neuroscience from Princeton University where he investigated the molecular mechanisms underlying mammalian learning and memory processes. Using genetic engineering techniques in mice, he continued this work at Boston University before joining Nature Neuroscience in late 2007. Prior to his formal training, he coordinated a clinical and academic research program at the Cardiovascular Research Institute at the University of California, San Francisco on projects concerning genetic and molecular basis of cardiovascular diseases and lipid/cholesterol disorders. Prior to his non-neuroscience stint at UCSF, he received an undergraduate training in neuroscience from New York University, Center for Neural Science and received Bachelor of Science degree in 1997.
    AbstractShow full text abstract about Scientific publishing is a natural part of the research ende...»
    Scientific publishing is a natural part of the research endeavor as it marks the end of one project and the start of another. Even so, the actual publication process spanning from manuscript submission, initial editorial evaluation, peer-review and the journal’s decision to publish a given manuscript may appear mysterious from the author’s perspective. In high profile, high impact journals where the published manuscripts are given exposure to the widest audience possible, the manuscript selection process can be especially arduous and competitive at times. This presentation will discuss the general issues and framework of publishing in high profile scientific journals, and will explain the editorial process and manuscript selection in Nature Neuroscience. Also included in the discussion are suggestions for efficient writing of scientific manuscripts and rebuttal letters, potential utility of presubmission inquiry, and transference of manuscripts and reviews from one journal to another in Nature Publishing Group’s portfolio and beyond.
    Lecture
  • Date:30ThursdayApril 2015

    From near and far- cancer-associated fibroblasts mediate inflammation during breast cancer progression and metastasis

    More information
    Time
    14:00 - 15:00
    Title
    Guest Seminar
    Location
    Wolfson Building for Biological Research
    Auditorium
    Lecturer
    Dr. Neta Erez
    Department of Pathology Sackler School of Medicine Tel Aviv University
    Organizer
    Department of Systems Immunology
    Contact
    Lecture
  • Date:30ThursdayApril 2015

    Prof. Sima Lev - Life Science Lecture

    More information
    Time
    15:00 - 16:00
    Title
    Epithelial-Mesenchymal Transition (EMT), combination therapy and drug resistance in Triple Negative Breast Cancer (TNBC)
    Location
    Dolfi and Lola Ebner Auditorium
    Lecturer
    Prof. Sima Lev
    Department of Molecular Cell Biology
    Organizer
    Life Sciences
    Contact
    Lecture

Pages