Pages
April 01, 2015
-
Date:29WednesdayApril 2015Lecture
Deviation from identity of macroscopic properties of enantiomers –via water chiral preference. (Is water chiral?)
More information Time 14:00Location Perlman Chemical Sciences Building
Room 404Lecturer Dr. Yosef Scolnik
IYAR (Israel Institute for Advanced Research). Weizmann InstituteOrganizer Department of Molecular Chemistry and Materials ScienceContact Details Show full text description of Abstract Mirror-image asymmetric molecules, i.e. enantiomer...» Abstract
Mirror-image asymmetric molecules, i.e. enantiomers, are classically considered as chemically identical. Parity violation by the nuclear weak force induces a tiny energy difference between chiral isomers. Upon combination with a massive amplification process, expansion of this difference to a detectable macroscopic level may be achieved. In our studies we have prove this in several systems: Stearoylserine "quasi peptide" formation
Solubility and cluster formation of Alanine
Peptide Transitions to alpha –helix, shortly described hereafter and others
We compared structural and dynamic features of synthetic D- and L-polyglutamic acid and polylysine molecules each of 24 identical residues. The helix and random coil configurations and their transition were determined in this study by circular dichroism (CD) and isothermal titration calorimetry (ITC) in water and deuterium oxide. Distinct differences in structure and transition energies between the enantiomer polypeptides were detected by both CD and ITC when dissolved in water. Intriguingly, these differences were by and large abolished in deuterium oxide. Our findings suggest that deviation from physical invariance between the D- and L-polyamino acids is induced in part by different hydration in water which is eliminated in deuterium oxide. We suggest that ortho-H2O, which constitutes 75% of bulk H2O, has a preferential affinity to L-enantiomers.In other words, these studies, prove that indeed water has chiral preferences, Accordingly, Heavy Water has no chiral preference. Differential hydration of enantiomers may have played a role in the selection of L-amino acids by early forms of life.
-
Date:29WednesdayApril 2015Lecture
Investigations of Implosions on the National Ignition Facility and discussion on the fusion yield from NIF
More information Time 15:15Location Edna and K.B. Weissman Building of Physical Sciences
Drory AuditoriumLecturer H. A. Scott, B. A. Hammel
Lawrence Livermore National Laboratory, Livermore, CA USAOrganizer Department of Particle Physics and Astrophysics
Plasma SeminarContact Details Show full text description of 15:00 – Light refreshments ...» 15:00 – Light refreshmentsAbstract Show full text abstract about Hydrodynamic instabilities are a primary impediment to the s...» Hydrodynamic instabilities are a primary impediment to the success of inertial confinement fusion (ICF), as they can severely degrade capsule performance [1]. Even with perfectly smooth capsules, the fill tube and capsule support provide perturbations that seed instabilities. Consequently,
understanding the evolution of perturbations and their effects on capsule performance is critical to the success of an ICF program. We discuss here the use of spectroscopic methods to diagnose the growth of hydrodynamic instabilities in imploding capsules. To understand capsule evolution and guide experimental design and interpretation, we use high-resolution HYDRA [2] simulations, postprocessed with Cretin [3], to simulate the spectra produced by capsules with specified initial perturbations. The
spectral simulations cover a wide range of conditions, from the multi-keV hot spot to the cold dense pusher.
For capsules with mid-Z dopants, the resulting X-ray spectrum can be analyzed to obtain information about the plasma conditions. An analysis of the dopant K-shell line emission has been used to estimate the mass of ablator material mixed into the hot spot [4]. Other spectral features can be used to provide information about the shell and further constrain the mixed mass. Other recent work has focused on using spectroscopy to quantitatively characterize the growth of perturbations. Capsules containing a small amount of argon in the gas produce sufficient emission before peak compression to provide radiographic information. The analysis of simulated spectra from capsules with machined perturbations demonstrates the possibility of extracting quantitative measures of perturbation growth.
References
[1] B.A. Hammel, et al, High Energy Density Physics, 6 (2010) 171.
[2] M. Marinak, et al, Phys. Plasmas 8 (2001) 2275.
[3] H.A. Scott, J Quant Spectrosc Radiat Transfer 71 (2001) 681.
[4] S.P. Regan et al. Phys. Rev, Lett. 111, 045001 (2013).
-
Date:30ThursdayApril 2015Lecture
Nanobots: vesicle-templates assembly and applications of functional nanocapsules
More information Time 11:00 - 12:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof Eugene PinkhassikOrganizer Department of Molecular Chemistry and Materials Science
Special SeminarContact -
Date:30ThursdayApril 2015Lecture
'Cellular Origin and Functional Specialization of Tissue-resident Macrophages
More information Time 11:00 - 12:00Location Wolfson Building for Biological Research
AuditoriumLecturer Dr. Martin GuilliamsOrganizer Department of Systems ImmunologyContact -
Date:30ThursdayApril 2015Colloquia
Spotting the elusive Majorana under the microscope
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical Sciences
AuditoriumLecturer Ali Yazdani
PrincetonOrganizer Faculty of PhysicsContact Details Show full text description of 11:00 – coffee, tea, and more...» 11:00 – coffee, tea, and moreAbstract Show full text abstract about Topological superconductors are a distinct form of matter th...» Topological superconductors are a distinct form of matter that is predicted to host boundary Majorana fermions. These quasi-particles are the emergent condensed matter analogs of the putative elementary spin-1/2 particles originally proposed by Ettore Majorana with the intriguing property of being their own anti-particles. The search for Majorana quasi-particles in condensed matter systems is motivated in part by their potential use as topological qubits to perform fault-tolerant computation aided by their non-Abelian characteristics. Recently, we have proposed a new platform for the realization of Majorana fermions in condensed matter, based on chains of magnetic atoms on the surface of a superconductor. This platform lends itself to measurements with the scanning tunneling microscope (STM) that can be used to directly visualize the Majorana edge modes with both high energy and spatial resolution. Using rather unique STM instrumentation, we have succeeded in creating this platform and have observed the predicted signatures of localized Majorana edge modes. I will describe our Majorana platform, the experiments to date, and the outlook for further experiments on Majorana fermions in condensed matter systems. -
Date:30ThursdayApril 2015Lecture
Demystifying publication process at Nature Neuroscience
More information Time 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Min Cho, PhD, Senior Editor
Nature Neuroscience, Nature Publishing GroupOrganizer Department of Brain SciencesContact Details Show full text description of Speaker Biography: Min Cho, Ph.D. is a senior editor of Nat...» Speaker Biography:
Min Cho, Ph.D. is a senior editor of Nature Neuroscience where he manages the selection of original research manuscripts for publication. He received his doctorate degree in molecular biology and neuroscience from Princeton University where he investigated the molecular mechanisms underlying mammalian learning and memory processes. Using genetic engineering techniques in mice, he continued this work at Boston University before joining Nature Neuroscience in late 2007. Prior to his formal training, he coordinated a clinical and academic research program at the Cardiovascular Research Institute at the University of California, San Francisco on projects concerning genetic and molecular basis of cardiovascular diseases and lipid/cholesterol disorders. Prior to his non-neuroscience stint at UCSF, he received an undergraduate training in neuroscience from New York University, Center for Neural Science and received Bachelor of Science degree in 1997.
Abstract Show full text abstract about Scientific publishing is a natural part of the research ende...» Scientific publishing is a natural part of the research endeavor as it marks the end of one project and the start of another. Even so, the actual publication process spanning from manuscript submission, initial editorial evaluation, peer-review and the journal’s decision to publish a given manuscript may appear mysterious from the author’s perspective. In high profile, high impact journals where the published manuscripts are given exposure to the widest audience possible, the manuscript selection process can be especially arduous and competitive at times. This presentation will discuss the general issues and framework of publishing in high profile scientific journals, and will explain the editorial process and manuscript selection in Nature Neuroscience. Also included in the discussion are suggestions for efficient writing of scientific manuscripts and rebuttal letters, potential utility of presubmission inquiry, and transference of manuscripts and reviews from one journal to another in Nature Publishing Group’s portfolio and beyond. -
Date:30ThursdayApril 2015Lecture
From near and far- cancer-associated fibroblasts mediate inflammation during breast cancer progression and metastasis
More information Time 14:00 - 15:00Title Guest SeminarLocation Wolfson Building for Biological Research
AuditoriumLecturer Dr. Neta Erez
Department of Pathology Sackler School of Medicine Tel Aviv UniversityOrganizer Department of Systems ImmunologyContact -
Date:30ThursdayApril 2015Lecture
Prof. Sima Lev - Life Science Lecture
More information Time 15:00 - 16:00Title Epithelial-Mesenchymal Transition (EMT), combination therapy and drug resistance in Triple Negative Breast Cancer (TNBC)Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Sima Lev
Department of Molecular Cell BiologyOrganizer Life SciencesContact