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February 18, 2016
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Date:02ThursdayMarch 2017Colloquia
Nonlinear phononics: coherent control of the crystal lattice and of the collective properties of solids
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Andrea Cavaliery
Max Planck GesellschaftOrganizer Faculty of PhysicsContact Abstract Show full text abstract about In this talk, I will discuss how coherent electromagnetic ra...» In this talk, I will discuss how coherent electromagnetic radiation at infrared and TeraHerz frequencies can be used to coherently rearrange atoms within the crystal lattice of a solid. The motion of atoms is large, and energy flows between different modes of the crystal. Such nonlinear phononics allows for the control of metal insulator transitions, magnetic phenomena, superconductivity and ferroelectricity.
I will also discuss how femtosecond x-ray beams from free electron lasers are integral to these studies, and are used to image structures during these non-equilibrium processes.
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Date:02ThursdayMarch 2017Lecture
Neuronal ensembles: emergent motifs of cortical function?
More information Time 11:30 - 11:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Rafael Yuste
Dept of Biological Sciences, Columbia University, NYOrganizer Department of Brain SciencesContact -
Date:02ThursdayMarch 2017Lecture
Cortical spike multiplexing using gamma frequency latencies
More information Time 12:45 - 12:45Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Dana H. Ballard
Dept of Computer Sciences, University of Texas at AustinOrganizer Department of Brain SciencesContact -
Date:02ThursdayMarch 2017Lecture
AMO Special Seminar
More information Time 14:00 - 15:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Dr. Tracy Northup
Universtität InnsbruckOrganizer Department of Physics of Complex SystemsContact -
Date:05SundayMarch 2017Lecture
Science and Clinical Orthopedics
More information Time 08:30 - 12:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Benjamin Alman, Keynote speaker
Duke UniversityOrganizer Department of Molecular GeneticsContact -
Date:05SundayMarch 2017Lecture
Sandbox- a Playground for Genomic Research and Science Innovation
More information Time 09:00 - 10:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Hadas Keren-Shaul
Life Science Core FacilitiesOrganizer Department of Life Sciences Core FacilitiesContact -
Date:05SundayMarch 2017Lecture
Chemical Physics Department Guest Seminar
More information Time 11:00 - 11:00Title TEERs for DEERs - advanced spectroscopy of correlated spins in molecules using a single spin sensorLocation Gerhard M.J. Schmidt Lecture HallLecturer Dr. Amit Finkler
University of StuttgartOrganizer Department of Chemical and Biological PhysicsContact Abstract Show full text abstract about Defects in the solid state are potentially suitable candidat...» Defects in the solid state are potentially suitable candidates for nanoscale sensing and imaging. Among these, the nitrogen-vacancy (NV) center in diamond has gained wide publicity due to its long coherence time, stability and wide temperature and frequency ranges of operation. With recent reports on the sensing of electron and nuclear spins from single proteins, we attempt to go one step further to the realm of correlated spins. I will present measurements of electron spins in spin-labeled molecules both at room temperature and at low temperature. I will show that it is possible to detect the dipolar coupling between two spin labels in a doubly-labeled peptide using a scheme we call "triple electron-electron resonance". This is a necessary step towards sensing of spins in correlated-electrons
systems. Together with quantum-assisted schemes and improvements in signal readout, I will offer methods with which we can tackle challenges in chemical physics, laying out a potential platform for a spin network.
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Date:05SundayMarch 2017Lecture
Seeing methanogens through computer simulations
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Qusheng Jin
Department of Earth Sciences University of OregonOrganizer Department of Earth and Planetary SciencesContact -
Date:05SundayMarch 2017Lecture
Personalized medicine for type 2 diabetes: Are we there?
More information Time 15:00 - 16:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Hilla Knobler
Institute of Diabetes, Endocrinology & Metabolism, Kaplan Medical Centre, Hebrew University School of MedicineContact -
Date:05SundayMarch 2017Lecture
Molecular Neuroscience Forum Seminar
More information Time 15:00 - 16:00Title Neurotrophic factor signaling in cerebellar developmentLocation Wolfson Building for Biological ResearchLecturer Carlos Ibanez
Weston Visiting Professor, Weizmann Institute of Science Department of Neuroscience Karolinska Institute Stockholm, SwedenOrganizer Department of Biomolecular SciencesHomepage Contact -
Date:06MondayMarch 2017Colloquia
"Surface studies and matter wave optics experiments with neutral helium beams"
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Bodil Holst
University of BergenOrganizer Faculty of ChemistryContact -
Date:06MondayMarch 2017Lecture
Metabolic regulation of normal and leukaemia stem cells: the role of reactive oxygen species, mitochondria transfer and nitric oxide
More information Time 14:00 - 15:00Title Cancer Research ClubLocation Max and Lillian Candiotty BuildingLecturer Prof. Tsvee Lapidot
Dept. of Immunology, Weizmann InstituteOrganizer Department of Immunology and Regenerative BiologyContact Abstract Show full text abstract about Bone marrow (BM) retained blood forming stem cells are prote...» Bone marrow (BM) retained blood forming stem cells are protected from DNA damaging agents including chemotherapy to prevent lethal infections and hematology failure. Stem cell chemotherapy resistance, requires dynamic interactions with BM stromal and endothelial cells and involves metabolic regulation of ROS, mitochondria transfer, and inhibition of NO. Leukemic stem cells initiate and maintain the disease and are the major target for clinical chemotherapy treatment. These malignant stem cells also reside in the BM and their chemotherapy resistance can lead to lethal leukemia relapse. Metabolic regulation of normal and leukemic stem cells in the bone marrow will be discussed. -
Date:06MondayMarch 2017Cultural Events
Dira Lehaskir - Children's theater
More information Time 17:30 - 17:30Location Michael Sela AuditoriumContact -
Date:07TuesdayMarch 2017Lecture
How did the first protein form(s) evolve?
More information Time 10:00 - 10:30Location Wolfson Building for Biological ResearchLecturer Dr. Maria Luisa Romero Romero
Member - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Short functional peptides are likely to have served as cruci...» Short functional peptides are likely to have served as crucial intermediates between a primordial RNA world and the extant protein world. Our working hypothesis is that relics of these ancestral peptides still exist in the form of key motifs in active sites of present-day proteins. One such motif, probably the most obvious one, is the P-loop (Walker A motif) that typically binds the transferred phosphate moiety of ATP. Overall, our results show that P-loop NTPases could have emerged from a relatively short P-loop containing peptide and that self-assembly played a key role in endowing biochemical function despite limited size and complexity. -
Date:07TuesdayMarch 2017Lecture
Designed by Nature: Reduced Protein Stability Prevents Promiscuous Protein Binding The Case of TEM1-β-Lactamase
More information Time 10:30 - 11:00Location Wolfson Building for Biological ResearchLecturer Ruth Khait
Member - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Protein-protein interactions play important roles in most ce...» Protein-protein interactions play important roles in most cellular processes. Proteins interact through chemical and structural complementarity of their mutual binding sites. Amino acids found in physical proximity form non-covalent interactions that stabilize the complex. Here we studied the evolution of PPI interfaces applying directed in vitro evolution on a random TEM library expressed on yeast surface. Our study focused on two specific questions: 1) How plastic is a well-defined PPI interface? For that purpose the TEM library was softly selected against its high affinity binder BLIP and analyzed by deep sequencing. 2) Is it possible to evolve new PPIs? Here the monomeric TEM library was selected against TEM-WT and other proteins to create new binders. Our results show that PPI interfaces are plastic and easily formed, hence evolution must actively act to prevent promiscuous protein binding. One mechanism which seems to be applied by nature for that purpose is keeping wild type proteins below their potential stability in a way that they are easily destabilized upon mutation. -
Date:07TuesdayMarch 2017Lecture
Mechanisms of calcium accumulation and mineralization in coccolithophores
More information Time 11:15 - 11:15Location Ullmann Building of Life SciencesLecturer Prof. Assaf Gal
Dept. of Plant and Environmental Sciences, The Weizmann Institute of ScienceOrganizer Department of Plant and Environmental SciencesContact -
Date:07TuesdayMarch 2017Lecture
MCB - Students seminar
More information Time 12:15 - 12:15Title TBALocation Wolfson Building for Biological ResearchOrganizer Department of Molecular Cell BiologyContact -
Date:07TuesdayMarch 2017Lecture
MIF as a therapeutic candidate for amyotrophic lateral sclerosis
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Adrian Israelson
Dept of Physiology and Cell Biology Ben-Gurion University of the Negev, Be'er-ShevaOrganizer Department of Brain SciencesContact -
Date:07TuesdayMarch 2017Lecture
“scientific paper writing - a survival guide”
More information Time 15:00 - 16:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Bodil Holst
University of BergenOrganizer Faculty of ChemistryContact Abstract Show full text abstract about author of the book “scientific paper writing - a survival gu...» author of the book “scientific paper writing - a survival guide” -
Date:08WednesdayMarch 2017Lecture
G-INCPM-Special Seminar - Prof. Yaron Shav-Tal, Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University - "Quantifying mRNA transcription on single alleles in single cells"
More information Time 11:00 - 12:15Location Nancy and Stephen Grand Israel National Center for Personalized MedicineLecturer Prof. Yaron Shav-Tal
Faculty of Life Sciences & Nano-medicine Research Center, Institute of Nanotechnology and Advanced Materials, Bar-Ilan UniversityOrganizer Faculty of BiochemistryContact Abstract Show full text abstract about I will describe approaches used to follow and quantify trans...» I will describe approaches used to follow and quantify transcription kinetics from single genes in fixed and living cells, using single-molecule RNA FISH and live-cell imaging. These studies have allowed us to examine transcription at high resolution during the cell cycle and to reveal new levels of regulation. We have also generated a method to tag endogenous genes on the mRNA and protein levels, and this has allowed us to use RNA FISH to differentiate between the transcriptional activity of various alleles of the same gene in single cells, to characterize a cellular response to stress, and to screen for compounds that interfere with the stress response.