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April 27, 2017

  • Date:29SundayJanuary 2023

    Insolation Forcing and Eastern Mediterranean aridity: Evidence from the Dead Sea and implications for climate projections

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    Time
    11:00 - 11:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerYochanan Kushnir
    Lamont-Dohert Earth Observatory Columbia University
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about The Mediterranean region stands out among other subtropical ...»
    The Mediterranean region stands out among other subtropical regions in its projected drying response to
    the global rise in atmospheric greenhouse gas concentrations. This drying trend has already emerged out
    of the normal, random climate variability in the sensitive Eastern Mediterranean (EM) region. To better
    understand the dynamical mechanisms responsible for this regional sensitivity, we turn to past protracted
    EM drying states during warm geological epochs. A unique view of the historical and pre-historical
    hydroclimate of the EM-Levant has been gleaned from the continued study of the sedimentary and
    geochemical record left by the lakes that filled the tectonic basin of the Dead Sea. We revisit the Late
    Quaternary sediment record retrieved during the 2010-2011 Dead Sea Deep Drilling Project (DSDDP). The
    sediments clearly indicate that the Levant was drier during past warm interglacials than during the adjacent
    glacials but nonetheless experienced large variations in the intensity of the regional aridity. During each
    interglacial, extended thick deposits of salts accumulated at the Lake bottom, during millennia of
    significant regional aridity and severely reduced Mediterranean rains. These dry states were interrupted
    by extended wet intervals, fed by rains that were supplied by a blend of tropical and Mediterranean
    moisture. To understand the underlying causes of the EM-Levant interglacial hydroclimate variations, we
    put the Dead Sea record in the context of the Northern Hemisphere orbital insolation variations and their
    impact on the global climate system. We show that the changes in EM hydroclimate portrayed by the
    DSDDP record during the interglacials, are entirely consistent with the response of the North Atlantic
    Ocean and the overlying atmosphere and surrounding land areas to the changes in the latitudinal insolation
    gradient, as determined by climate models and evident by surface temperature proxies. This perspective
    provides new information regarding the dynamical processes responsible for the ongoing, greenhouse
    gas forced, EM drying.
    Lecture
  • Date:30MondayJanuary 202302ThursdayFebruary 2023

    The 79th Katzir Conference Noncoding RNAs in Development and Cell Differentiation

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    Time
    08:00 - 08:00
    Location
    The David Lopatie Conference Centre
    Chairperson
    Igor Ulitsky
    Homepage
    Conference
  • Date:30MondayJanuary 2023

    Microsecond Structural Dynamics of Protein, DNA and RNA Revealed by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy (2D FLCS)

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Tahei Tahara
    Molecular Spectroscopy Laboratory, RIKEN, Japan
    Organizer
    Faculty of Chemistry
    Homepage
    Contact
    AbstractShow full text abstract about Single-molecule spectroscopy, combined with fluorescence res...»
    Single-molecule spectroscopy, combined with fluorescence resonance energy transfer, has been intensively utilized for studying the structural dynamics of protein, DNA, and RNA. However, observation of the dynamics on the microsecond timescale is challenging due to the low efficiency of collecting photons from a single molecule. To realize quantitative investigations of structural dynamics with a sub-microsecond time resolution, we developed new single-molecule spectroscopy, i.e., two-dimensional fluorescence lifetime correlation spectroscopy (2D FLCS). In this 2D FLCS, we use a high-repetition short pulse laser for photoexcitation and analyze the correlation of the fluorescence lifetime from the donor of a FRET pair. The obtained information is represented in the form of a 2D fluorescence lifetime correlation map using the inverse Laplace transform. 2D FLCS can visualize the structural dynamics of complex molecules in the equilibrium condition with a sub-microsecond resolution at the single-molecule level.
    In this presentation, I will talk about the principle of 2D FLCS and its application to the study of the structural dynamics of protein, DNA, and RNA, in particular, the most recent study on the folding/unfolding dynamics of an RNA riboswitch. Based on the observed microsecond folding dynamics, we proposed the molecular-level mechanism for transcription control by the riboswitch.
    Colloquia
  • Date:31TuesdayJanuary 2023

    Combining mass spectrometry and nanodiscs to investigate membrane protein-lipid interactions

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Michael Marty
    Department of Chemistry and Biochemistry at The University of Arizona
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Dr. Michael Marty is an Associate Professor in the Departmen...»
    Dr. Michael Marty is an Associate Professor in the Department of Chemistry and Biochemistry at The University of Arizona. His research applies nanodiscs with mass spectrometry to study interactions of membrane proteins with and within lipid bilayers. This “choose your own adventure” talk will cover lipidomic analysis of the monolayer of lipids surrounding membrane proteins, lipid-dependent oligomerization of amyloid proteins and viral ion channels, and/or detailed biophysical characterization of lipid binding to specific sites on membrane proteins with native mass spectrometry.
    Lecture
  • Date:31TuesdayJanuary 2023

    Chemical and Biological Physics Guest Seminar

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    Time
    11:00 - 11:00
    Title
    Structure and ultrafast dynamics at the water interface revealed by phase-sensitive nonlinear spectroscopy
    Location
    Perlman Chemical Sciences Building
    LecturerProf Tahei Tahara
    Molecular Spectroscopy Laboratory, Riken, Japan
    Organizer
    Department of Chemical and Biological Physics
    Contact
    Lecture
  • Date:31TuesdayJanuary 2023

    A meta'omics perspective on the functional potential and regulation of metabolic activity in the global ocean microbiome

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    Time
    11:30 - 12:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Shinichi Sunagawa
    ETH Zurich
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:31TuesdayJanuary 2023

    My adventures in the rat interactive foraging facility (RIFF)

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    Time
    12:30 - 13:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Eli Nelken
    ELSC-The Hebrew University of Jerusalem
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about We developed an arena (called colloquially the RIFF) for joi...»
    We developed an arena (called colloquially the RIFF) for jointly studying behavior and neural activity in freely-behaving rats. The RIFF operates as a state machine, allowing us to implement a large number of different behaviors as Markov Decision Processes and therefore to analyze much of the data within the theoretical framework of reinforcement learning. In the studies I will show here, we recorded neural activity from auditory cortex while rats performed auditory-guided behavior. We observed an intricate interplay between behavior and neural activity that was much richer than we expected.
    Lecture
  • Date:31TuesdayJanuary 2023

    Chemical Evolution: From Origins of Life to Biotechnology

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    Time
    14:00 - 15:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerDr. Moran Frenkel-Pinter
    Institute of Chemistry The Hebrew University of Jerusalem
    Organizer
    Department of Chemical and Structural Biology
    Contact
    Lecture
  • Date:01WednesdayFebruary 2023

    The development and molecular mechanisms of crystal-forming cells

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    Time
    10:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerDr. Dvir Gur
    Departments of Molecular Genetics
    Organizer
    Department of Brain Sciences
    Contact
    Lecture
  • Date:01WednesdayFebruary 2023

    M.Sc thesis defense: “Fermi-polaron description of excitonic scattering processes in layered systems from first principles”

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    Time
    11:00 - 12:00
    Location
    Perlman Chemical Sciences Building
    LecturerGuy Voscoboynik
    M.Sc student of Dr. Sivan Refaely Abramson
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    AbstractShow full text abstract about Layered materials exhibit unique charge and energy transfer ...»
    Layered materials exhibit unique charge and energy transfer characteristics, making them promising candidates for emerging photophysical and photochemical applications, and particularly in energy conversion and quantum information science. In two-dimensional systems, spatial confinement in a certain dimension causes reduced dielectric screening and enhanced Coulomb interaction compared to bulk materials. Upon light excitation, the relaxation processes of the charge and energy carriers, as well as their rearrangement in the lateral plane, allow for unique and structure-specific interaction dynamics of the electrons and holes in these systems and of their bound states - neutral and charged excitons. In particular, these dimensionality effects induce strong exciton-electron and exciton-hole interactions in doped or gated systems, where optical excitations coexist alongside electronic excitations. These interactions dominate the exciton decay and diffusion and introduce bound three-particle states in such systems. A many-particle theoretical picture of the formation and propagation of these states is crucial for proper tracking and understanding of the interaction pathways, crystal momentum effects, the involved particle-particle coupling and their relation to the underlying structure, dimensionality, and symmetry.

    Lecture
  • Date:01WednesdayFebruary 2023

    Resilience of photosynthetic organisms in changing environments: from Cyanobacteria to Plants

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    Time
    15:30 - 16:30
    Location
    Via Zoom: https://weizmann.zoom.us/j/95255951733?pwd=ckNINThodTFWL0s3Rm1KSHgvVnU5QT09
    LecturerDr. Giovanna Capovilla
    MIT
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:02ThursdayFebruary 2023

    Personalized medicine based on deep human phenotyping

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    Time
    09:00 - 09:00
    Location
    Max and Lillian Candiotty Building
    LecturerDr. Adina Weinberger
    Biomedical Research Unit
    Organizer
    Department of Life Sciences Core Facilities
    Contact
    Lecture
  • Date:02ThursdayFebruary 2023

    Physics Colloquium

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    Time
    11:15 - 12:30
    Title
    Quantum materials by design
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerProf. Cory Dean
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about The electronic properties of a material are dictated by both...»
    The electronic properties of a material are dictated by both the composition and arrangement of its atomic lattice. Combining elemental atoms selected from the periodic table in principle provides for infinite variety of materials to be realized. However, thermodynamic constraints limit which atoms may bond into which symmetry classes; materials may or may not be air sensitive; synthesis conditions may be impractical; impurities and defects may substantially obscure intrinsic electronic properties; and the resulting electron behaviour may not be predictive owing to phenomena such as strong electron interactions, spontaneous magnetic ordering, fermi-surface reconstruction or other effects not captured by single-particle band-structure calculations. In this talk, I will explore new approaches to synthesizing quantum materials by augmenting the atomic lattice structure in 2D materials with a superimposed superlattice potential. Artificially engineering lattice potentials provide opportunities to synthesize materials beyond the periodic table, with the ultimate promise to be able to realize and manipulate arbitrary electronic states, by design. Opportunities and challenges, in this exciting new field will be reviewed, and the prospects for quantum simulation in a solid-state platform will be discussed.

    Colloquia
  • Date:02ThursdayFebruary 2023

    Active vision and vision for action

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    Time
    12:30 - 13:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Daniel Kerschensteiner
    Washington University School of Medicine St. Louis
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about  Vision is an active sense in which an animal's gaze an...»
     Vision is an active sense in which an animal's gaze and pupil shape the content of the retinal image. In the first part of my talk, I will discuss how the viewing strategies of mice align with the neural architecture of their visual system to accomplish an essential visual task: predation. In the second part of my talk, I will compare the hunting behavior of mice to that of a specialized predator, similar in size but distant in evolution, and present our initial insights into the organization of visual information in this animal. Finally, I will present ongoing work indicating that the pupillary reflex arc implements a more complex stimulus-response function than previously thought. I will discuss the underlying neural mechanisms and potential purpose and show conservation from mice to humans. 

    Lecture
  • Date:02ThursdayFebruary 2023

    Faculty Seminar

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    Time
    12:45 - 14:00
    Title
    Computational Imaging for Scientific Discovery: From Cloud Physics to Black Holes Dynamics
    Location
    Jacob Ziskind Building
    LecturerAviad Levis
    Caltech
    Organizer
    Department of Computer Science and Applied Mathematics
    Contact
    Lecture
  • Date:02ThursdayFebruary 2023

    Silver mines, the rise of money and the advent of democracy

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    Time
    14:00 - 14:00
    Location
    Sussman Family Building for Environmental Sciences
    Contact
    Lecture
  • Date:02ThursdayFebruary 2023

    Epigenetic Liquid Biopsy

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    Time
    14:00 - 15:00
    LecturerProf. Yuval Dor
    Department of Developmental Biology and Cancer Research The Institute for Medical Research Israel-Canada The Hebrew University-Hadassah Medical School
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:02ThursdayFebruary 2023

    Silver mines, the rise of money and the advent of democracy

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    Time
    14:00 - 14:00
    Title
    EPS Department and Kimmel Center for Archaeological Science
    Location
    Sussman Family Building for Environmental Sciences
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about Over the last 2½ millenia, the world economy depended on pre...»
    Over the last 2½ millenia, the world economy depended on prevailing currencies: the Athenian owl (530-
    168 BCE), the Roman denarius (211 BCE-250 AD), the Spanish piece-of-eight (16th to 18th C), and today
    the US dollar. These reference monies were accepted everywhere and all, at least in the beginning, were
    made of silver. What is so special about this metal? Silver is useless and rare, but still abundant enough to
    match the wealth of nations and of their long-distance trade.
    Silver ores are associated with rare and recent tectonic environments, the Mediterranean world, notably
    the periphery of the Aegean Sea and Southern Iberia, and the American cordillera, Peru and Mexico. In
    contrast, they were markedly scarce in South and East Asia.
    After the virtual destruction of soils by the Anatolian farmers at the end of the Bronze Age, the Near and
    Middle East societies depended almost exclusively on the agriculture of Egypt and Mesopotamia. The
    Late Bronze Age collapse (ca. 1200 BCE) corresponded to the migration of Greek people and resulted in
    the annihilation of all the empires outside of the flood plains. Silver by weight was nevertheless used to
    save populations from famine and trade wheat, barley and copper.
    Military innovations, hoplites and their phalanx, were, with silver mines, the main resources of the Greeks.
    Mercenaries received their wages in silver, notably through the tributes exacted in silver by the
    Achaemenid (Persion) kings. By minting silver, the returning Greek mercenaries emerged as strong middle
    classes . They soon claimed their share of the power, toppled the tyrants, and installed democracy in
    many poleis from Greece and Southern Italy. Modern economics teaches us that egalitarian distribution of
    wealth is unfortunately unstable and this case is well illustrated by Syracuse.
    At the beginning of the common era, the Roman Empire found itself the owner of centuries of silver
    extracted from Greece and from Iberia. This bullion was used to buy luxury products, frankincense from
    Arabia, spices and cotton from India, ivory and precious wood from Africa. Leakage of silver towards the
    Indian Ocean was so strong that coins were quickly debased by copper and by 250 AD most of the silver
    had been lost. The progressive replacement of silver by a bimetallic system, gold for the rich and bronze
    for the working class, progressively fractured the society and ushered the brutal Middle Age regimes.
    Silver famine had finally destroyed the democratic ideal of the Greeks. This is food for thought as
    disappearing mining resources may severely affect our current vision of societies.
    Lecture
  • Date:05SundayFebruary 2023

    Forecasting surface weather and storm tracks at one-month leads: role of the stratosphere and the Madden Julian Oscillation

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    Time
    11:00 - 11:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerChaim Garfinkel
    The Hebrew University of Jerusalem
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about The traditional approach to weather forecasting on one- to t...»
    The traditional approach to weather forecasting on one- to two-week timescales utilizes weather forecasting models, but on timescales longer than two weeks, the value of deterministic (or ensemble-based probabilistic) forecasts weakens. This is due to the presence of chaotic variability in the atmosphere. Yet certain modes of variability in the climate system have timescales longer than this two-week threshold, and the key to longer-scale prediction is to take advantage of these modes when they open up windows of opportunity. By understanding the impacts of these modes of variability on surface weather, the potential for improved forecasts on a monthly timescale can be demonstrated and eventually realized. 
    Two such classes of modes of variability are stratospheric variability (both in the tropical and polar stratosphere) and tropical tropospheric variability (e.g. the Madden-Julian Oscillation and El Nino). For example, both polar stratospheric sudden warmings and the Madden-Julian Oscillation have been shown to influence European and Mediterranean weather, but it is unclear (1) what mechanism(s) underlie these connections, (2) how far in advance the impacts can be predicted, (3) what governs the magnitude of the surface impact, and (4) how well models capture these connections. This talk will review progress made towards addressing these issues over the past several years in my group.
    Lecture
  • Date:05SundayFebruary 2023

    Touch and Go: The multifaceted roles of singlet oxygen in plant stress signaling

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerDr. Eugene Koh
    Temasek Life Sciences Laboratories
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture

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