• Picture of Prof. Idit Shachar

    Prof. Idit Shachar

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    Analyze the pathway regulateing the survival cascades in Chronic lymphocytic leukemia
    Collaboration with:  Dr Michal Haran, Kaplan Medical center
    Follow the mechanisms controlling homing of immune cells in health and disease.
    Determine the mechanisms regulating peripheral B cell maturation and survival in health and disease.

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  • Picture of Prof. Philipp Selenko

    Prof. Philipp Selenko

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    Neuronal alpha-synuclein aggregation in Parkinson's disease
    Collaboration with:  Daniella Goldfarb, Hagen Hofmann, Ori Avinoam, Atan Gross, Ami Navon
    Structural Biology, Cell Biology, Neurobiology, Biophysics
    NMR, EPR, smFRET, cryoEM, CLEM, optical microscopy, correlative imaging methods, advanced mammalian cell models.
    Cellular regulation of CPEB4 liquid-liquid phase separation
    Collaboration with:  Daniella Goldfarb, Hagen Hofmann, Koby Levi
    Structural Biology, Cell Biology, Neurobiology, Biophysics
    NMR, EPR, smFRET, cryoEM, CLEM, optical microscopy, correlative imaging methods, advanced mammalian cell models.

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  • Picture of Prof. Rony Seger

    Prof. Rony Seger

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    The nuclear translocation of signaling protein as a drug target for cancer and inflammation
    The nuclear translocation of ERK
    The nuclear translocation of JNK and p38
    Develop peptide inhibitors of the nuclear translocation of ERK/JNK/p38 for the cure of cancer and inflammation
    Development of small molecular weight inhibitors of the nuclear translocation of ERK for the cure of cancer
    The subcellular localisation of AKT
    The mechanisms and roles of MEK nuclear translocation
    ERK1c in the regulation of Golgi fragmentation
    The mechanisms of golgi translocation of ERK1c
    Substrates of ERK1c in the Golgi
    Mechanism of ERK1c-regulated Golgi architecture

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  • Picture of Prof. Menahem Segal

    Prof. Menahem Segal

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    Intracellular calcium and structural/functional plasticity in cultured neurons.
    Collaboration with:  Dr. Eduard Korkotian
    Human Embryonic Stem Cells of Fragile X patients
    Collaboration with:  Prof. Dalit Ben Yosef (TAU)
    Network activity in cultured neurons
    Collaboration with:  Professor Elisha Moses (Physics)

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  • Picture of Prof. Adam Schwimmer

    Prof. Adam Schwimmer

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    String theory.
    Conformal field theory.
    Dynamics of gauge theory.
  • Picture of Dr. Osip Schwartz

    Dr. Osip Schwartz

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    Laser-enhanced electron microscopy
    Spatial and temporal shaping of electron wavefunction
    Transmission electron microscopy with laser-based electron optics
    Probing physical vacuum with strong laser fields
    Tabletop photon-photon scattering experiments
    Development of megawatt-class cavities with tightly focused mode

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  • Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

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    Brain-immune axis in Health and Diseases; from gene to behavior
    Collaboration with:  Prof. Ido Amit
    Immunotherapy to defeat Alzheimer’s disease
    Microbiome and Alzheimer’s disease
    Collaboration with:  Prof. Eran Elinav
    Diabetes as a risk factor in Alzheimer’s disease
    Collaboration with:  Prof. Naomi Habib, Hebrew University; Prof. Anna Greka, Broad Institute, Boston, USA.
    The Spleen –Brain axis in Alzheimer’s disease
    Familial Alzheimer’s disease
    Collaboration with:  Prof. Judit Aaron, Rambam hospital; Prof. Falik, Hagalil Hospital.
    ALS profiling at the transcriptomic level
    Collaboration with:  Prof. Ido Amit
    Immuno-Proteasome in Alzheimer’s disease
    Collaboration with:  Dr. Yifat Marbl

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  • Picture of Prof. Oren Schuldiner

    Prof. Oren Schuldiner

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    A genetic dissection of developmental axon regeneration
    Molecular mechanisms of neuronal remodeling during development: Developmental axon pruning in Drosophila
    The role of cell-cell interaction in regulating developmental axon pruning
    The role of intracellular signaling in regulating developmental axon pruning
    The role of trafficking in regulating developmental axon pruning
    Glia and their effect on neuronal growth and remodeling

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  • Picture of Prof. Maya Schuldiner

    Prof. Maya Schuldiner

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    Uncovering tethers, functions and regulators of membrane contact sites in yeast
    Mitochondria-ER contact sites
    Peroxisome-Lipid Droplet contact sites
    Nucleus-Mitochondria contact sites
    The proteome of contact sites
    Targeting and translocation to Organelles
    Uncovering a role for the Ssh1, the alternative, translocon in yeast
    Deciphering targeting of proteins to mitochondria
    Targeting of membrane proteins to peroxisomes
    Targeting of low-hydrophobicity SS proteins to the ER
    Targeting of proteins to the surface of the ER
    Uncovering new peroxisomal proteins and their functions
    Collaboration with:  Dr. Einat Zalckvar
    Metabolite transport across the peroxisome membrane
    Peroxisome contact sites
    Peroxisome quality control
    Peroxisome targeting
    New peroxisomal enzymes and their functions
    Pexophagy
    Peroxisomes in metabolism
    Novel methodologies for systematic exploration of yeast organelle protein functions
    Creation of versatile yeast libraries
    High throughput electron microscopy techniques
    Translocation sensors

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