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Prof. Michal Schwartz
Brain-immune axis in Health and Diseases; from gene to behaviorCollaboration with: Prof. Ido AmitImmunotherapy to defeat Alzheimer’s diseaseMicrobiome and Alzheimer’s diseaseCollaboration with: Prof. Eran ElinavDiabetes as a risk factor in Alzheimer’s diseaseCollaboration with: Prof. Naomi Habib, Hebrew University; Prof. Anna Greka, Broad Institute, Boston, USA.The Spleen –Brain axis in Alzheimer’s diseaseFamilial Alzheimer’s diseaseCollaboration with: Prof. Judit Aaron, Rambam hospital; Prof. Falik, Hagalil Hospital.ALS profiling at the transcriptomic levelCollaboration with: Prof. Ido AmitImmuno-Proteasome in Alzheimer’s diseaseCollaboration with: Dr. Yifat Marbl
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Prof. Oren Schuldiner
Mechanisms of neuronal circuit remodelingThe role of cell-cell interaction in regulating developmental axon pruningThe role of intracellular signaling in regulating developmental axon pruningThe role of trafficking in regulating developmental axon pruningCoordination of remodeling of different neurons within a circuitA metabolic analysis of neuronal remodelingMechanisms of circuit assemblyCollaboration with: Wiring neuronal circuits in the Drosophila mushroom bodyMechanisms regulating axon growth potentialCytoskeleton during developmental axon regrowthComparison of the transcriptional programs underlying initial axon outgrowth, developmental regrowth and regeneration following injury.
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Prof. Maya Schuldiner
Uncovering tethers, functions and regulators of membrane contact sites in yeastMitochondria-ER contact sitesPeroxisome-Lipid Droplet contact sitesNucleus-Mitochondria contact sitesThe proteome of contact sitesTargeting and translocation to OrganellesUncovering a role for the Ssh1, the alternative, translocon in yeastDeciphering targeting of proteins to mitochondriaTargeting of membrane proteins to peroxisomesTargeting of low-hydrophobicity SS proteins to the ERTargeting of proteins to the surface of the ERUncovering new peroxisomal proteins and their functionsCollaboration with: Dr. Einat ZalckvarMetabolite transport across the peroxisome membranePeroxisome contact sitesPeroxisome quality controlPeroxisome targetingNew peroxisomal enzymes and their functionsPexophagyPeroxisomes in metabolismNovel methodologies for systematic exploration of yeast organelle protein functionsCreation of versatile yeast librariesHigh throughput electron microscopy techniquesTranslocation sensors
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Dr. Rita Schmidt
Developing new tools for human MRI, especially at ultra-high field 7T MRI scanner, aiming to better understand the human brain functionDeveloping new methods to improve the spatial and temporal resolution in functional brain MRIDeveloping new contrast methods for functional MRI to study brain functionAdvancing dedicated MR pulse sequences to achieve fast and ultrafast high quality MR imaging and spectroscopic imagingBoosting the accessible MR signal in localized functional brain trials
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Prof. Avigdor Scherz
Quantification of atoms, groups and molecules electronegati using metal substituted bacteriochlorophylls and application to chemical reactivity.Resolving the forces which drive membrane protein assembly.The mechenism behind generation of reactive oxygen species (ROS) by illuminating novel bacteriochlorophyll derivatives and their application in photodynamic therapy (PDT) of tumors.
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