Department of Physics of Complex Systems

Head Prof. Elisha Moses

Picture of Prof. Elisha Moses
Head

Prof. Elisha Moses

Office +972-8-934-3139

Overview

The Department of Physics of Complex Systems pursues two main directions, Atomic, Molecular and Optical (AMO) physics and the physics of Soft and Biological Matter. Contemporary topics in AMO physics range from atto-second pulses and intense lasers, through precision spectroscopy of ultracold atoms, molecules or ions, to quantum information and quantum optics. Soft and biological physics are characterized by wide ranging complexity that can often be simplified by considering fundamental physical concepts and principles. The Department consists of slightly under 20 groups, of which about two thirds are experimentalists and one third are theoreticians.

Atomic, Molecular and Optical Physics

The AMO groups in the Department of Physics of Complex Systems study a wide variety of topics in nonlinear and quantum optics, atomic and molecular physics. Of interest are the properties of atoms and ions at ultra-cold temperatures where full control of individual atoms and photons is possible and quantum phenomena are manifested. These unique properties can be applied for quantum sensing, simulations and computing and study of new physics. Both theoretical and experimental aspects of Quantum Computation comprise an important and very significant goal of the research.

A particularly rich field of study is that of the interaction of ultrashort optical pulses with atoms, molecules, electrons and solids, which enables the measurement of ultrafast dynamics, allows the acceleration of electrons and protons, and generates new radiation sources for bio-medical applications. In addition, investigations of the geometrical quantum nature of light are conducted, along with its use for simulating general relativity in the lab.

Soft Matter and Biological Physics

The theoretical issues in soft matter cover non-equilibrium processes and aspects of emergent properties, of frustration and of material structure, all of which can be approached using the tools of statistical mechanics coupled with a deep mathematical description of organization in matter. Structures in liquid and organic crystals, as well as in viscoelastic material yield insight on the underlying physical processes and mechanisms. In biological systems, mechanisms that determine the size of cells can be obtained using physics modeling and theoretical concepts. In considering the statistical physics of turbulence, special emphasis is made on broken and emerging symmetries, with important implications for conformal invariance in inverse turbulent cascades and recently for the kinetic and hydrodynamic theory of emerging viscous electronics.

The experimental labs treat such diverse systems as ants, single molecules, neuronal cultures, one dimensional organisms, and even human groups. A unifying theme lies in relating the properties of the constituent parts to those of the emerging whole. Biological computation is treated in social contexts such as ant colonies and in devices comprised of living neurons. Emergent properties such as synchronization of activity, decision making and resource sharing are among the novel phenomena that have been discovered in these systems. Turbulence in viscoelastic media is studied in microfluidic environments.

Department of Particle Physics and Astrophysics

Head Prof. Ran Budnik

Picture of Prof. Ran Budnik
Head

Prof. Ran Budnik

Office +972-8-934-4462

Overview

The Department of Particle Physics and Astrophysics is engaged in both experimental and theoretical research, in various directions. These include elementary particle physics, field theory, string theory, theoretical astrophysics, observational astrophysics, particle astrophysics, relativistic heavy ion physics, molecular physics, nuclear physics, plasma physics, and radiation detection physics.

Department of Molecular Genetics

Head Prof. Yitzhak Pilpel

Picture of Prof. Yitzhak Pilpel
Head

Prof. Yitzhak Pilpel

Office +972-8-934-6058

Overview

The molecular basis of genetics and related biological processes are under investigation in our Department. The investigators approach these processes from the most reduced and reconstructed systems up to more systemic and computational analysis. Different organisms are employed including virus, yeast, Drosophila, mouse and human. These animal models and cell culture systems are used to study the mechanisms of;
a. Basic processes in gene expression, such as transcription, translation and protein degradation.
b. Cellular responses to various stimuli, such as cytokines, growth factors and exposure to DNA-damage.
c. Regulation of cell growth, senescence, differentiation and death.
d. Development; Mechanistic view of zygote to embryo transition and development of various organs, such as brain, muscles, bones and pancreas.
e. Genetic and acquired diseases such as cancer and virus infection. Embryonic stem cell biology, early development and advance human disease modeling.
f. Study of pluripotent stem cell biology and epigenetic reprogramming.
g. Computational and system biology. The function/evolution of genes and their diversification.

Department of Materials and Interfaces

Head Prof. Leeor Kronik

Picture of Prof. Leeor Kronik
Head

Prof. Leeor Kronik

Office +972-8-934-4993

Overview

Activities in the Department span a wide range of topics from soft, composite and hard materials to energy research, nanoscience, and biological materials. A unifying theme is the study of material functionality and its relation to fundamental properties at multiple scales. These properties may be mechanical, structural, chemical, electronic, magnetic, optical, and more. Some examples are:

How do shapes and sizes of nm-sized particles affect their properties?

How can we tune the properties of solar cells by manipulating their material interfaces?

How does friction in knee and hip joints depend on polyelectrolytes that lubricate them?

How can we design self-assembling (bio)chemical systems?

 

THE RESEARCH IS BASED ON AN INTERDISCIPLINARY APPROACH, and indeed the scientists bring complementary experience in chemistry and physics, including both theory and experiment.

Department of Molecular Cell Biology

Head Prof. Eldad Tzahor

Picture of Prof. Eldad Tzahor
Head

Prof. Eldad Tzahor

Office +972-8-934-3715

Overview

The molecular mechanisms underlying cell structures, dynamics and fate, and their involvement in embryonic development and cancer are among the primary topics of interest of the Department. These include studies on the mode of action of growth factors and the nature of signals triggered by them in target cells following binding to specific surface receptors. Growth regulation is also approached through the study of suppressor genes encoding such proteins as p53, which inhibit proliferation and drive cells towards differentiation or apoptosis. These studies, focusing on the mechanisms stimulate cell proliferation, differentiation, or death, can elucidate the basis for cancerous transformation in a large variety of systems. Overproduction or hyperactivation of growth-promoting systems was shown to have an oncogenic (cancer-causing) effect, and a similar process may be induced when growth-suppressor or apoptosis-inducing genes fail to function. The levels at which cell structure, activity and fate are studied in this department and the focus of these studies are many and diverse, including the characterization of soluble growth factors and their receptors, the nature of complex signal transduction pathways, the action of specific regulators of cytokine action, rearrangement of genes associated with oncogenic processes, and the properties of tumor suppressor and apoptosis promoting genes. Since such processes involve networks of interacting factors, we are also interested in mathematical modeling and computerized analysis of biological gene circuits.

In addition, there is broad interest in the molecular mechanisms of cell adhesion and their involvement in the regulation of cell fate. These studies include characterization of the basic rules underlying adhesive interactions, the binding of surface-associated adhesion molecules with the cytoskeleton, and the nature of growth- and differentiation-promoting signals triggered by adhesive interactions. Of special interest are proteins such as β-catenin, which play a crucial role in reinforcing cell-cell adhesions as well as triggering gene expression.

Department of Mathematics

Head Prof. Omri Sarig

Picture of Prof. Omri Sarig
Head

Prof. Omri Sarig

Office +972-8-934-4305

Overview

The principal research interests of the department lie in the broadly understood areas of analysis, probability, algebra, and geometry.

Topics covered in Analysis include operator and matrix theory, spectral theory, linear and nonlinear ordinary and partial differential equations, functional and harmonic analysis, ergodic theory and dynamical systems, control theory in its various manifestations, optimization, game theory, approximation and complexity of functions, numerical analysis, singularity theory and robotics.

Research in Probability theory covers random walks and graphs, motion in random media, percolation, random matrices, Gaussian fields and other probabilistic models in mathematical physics.

Areas of Geometric research include the structure of finite and infinite dimensional spaces, analytic, real algebraic and semi-algebraic geometry, typology of foliations and complex vector fields.

The Algebraic direction includes some aspects of algebraic geometry, geometric group theory, Lie Theory, representation theory, quantum groups, number theory, automorphic forms, ring theory, statistics of Young diagrams, algebraic combinatorics and enveloping algebras, invariants and crystals.

For the research done at our sister department, the Department of Scomputer Science and Applied Mathematics, see here.

Department of Immunology

Head Prof. Steffen Jung

Picture of Prof. Steffen Jung
Head

Prof. Steffen Jung

Office +972-8-934-2787

Overview

The immune system was originally recognized for its role in defense of the organism against pathogens, including bacteria and viruses. However, we have come to realize that the system not only reacts to exogenous pathogen attacks, but also to internal challenges posed by tissue remodeling, aging, metabolic unbalance and cancer.  Moreover, immune cells are also critically involved in normal developmental processes and the maintenance of adult homeostasis in light of innocuous and beneficial environmental challenges such as the microbiome. 

Research in the Department of Immunology addresses the challenge to understand contributions of immune cells to physiology and pathophysiology, with the aim to deepen our knowledge and develop new strategies for therapeutic intervention. Accordingly, our research spans a wide range from studying basic mechanisms of development, inter-cellular communication, cell trafficking and effector functions of immune cells to the definition of their specific roles in aging, autoimmune disorders, allergies and cancer. 

Department members investigate cellular and molecular mechanisms underlying immune disorders, such as aging, immunodeficiencies, innate immunopathologies, autoimmunity, as well as infectious diseases. Using pre-clinical mouse models and patient samples, we develop novel therapeutic strategies including check-point blockade, immunotherapies and improved vaccination protocols. We develop and employ state-of-the-art approaches ranging from intra-vital imaging and conditional gene manipulation, to advanced bulk and single cell genomics and proteomics to uncover physiological and pathological roles of the immune system.

For more details on our exciting research projects and specific groups in the Immunology Department, please see our web page https://www.weizmann.ac.il/immunology/

Department of Earth and Planetary Sciences

Head Prof. Yinon Rudich

Picture of Prof. Yinon Rudich
Head

Prof. Yinon Rudich

Office +972-8-934-4237

Overview

The research in this department is dedicated to understanding the complex inter-relationships among the major Earth Systems and on the human impact on the Earth's environment and climate. In addition,  research is conducted on planetary atmospheres and planetary geomorphologies.

The Department's research activities have several general areas of activities. One focuses on water and includes hydrology, geochemistry, land-plant-atmosphere interactions, and oceanography. A second activity is in the use of stable isotopes for reconstructions of paleoclimatic and of biosphere-atmosphere dynamics, and a third is in the area of atmospheric chemistry and dynamics, and cloud physics. The fourth area of research is in planetary sciences.   Our research requires knowledge of the interdependent components that together constitute the "environment", as well as a commitment to protect this environment by improving the manner in which air, water, land, and energy are utilized by humans. The Department is distinguished by the interactions among scientists from different backgrounds and expertise, which is critical for achieving a comprehensive understanding of the global environment and planetary sciences.

The department promotes international collaborations based on short- and long-term visits for research and training by scientists who complement existing expertise in the Department. The interdisciplinary nature of the Department is well reflected in the academic training of the research students. Their backgrounds vary from physics, chemistry, and mathematics through geology to biology. We encourage the participation of students who are interested in not only investigating in depth a specific subject but who are also interested in a broader and integrative approach to science.

Department of Condensed Matter Physics

Head Prof. Eli Zeldov

Picture of Prof. Eli Zeldov
Head

Prof. Eli Zeldov

Office +972-8-934-2892

Overview

The scientific activity of the department is mainly concentrated around the experimental and theoretical research in quantum solid state physics. It includes experimental research of mesoscopic physics, quantum Hall physics, topological states of matter, high temperature superconductors, two and one dimensional superconductors, metal-insulator transition, carbon nanotubes, semiconductor nanowires, and study of material growth. The theoretical efforts concentrate on similar subjects with added work on disordered materials, cold atoms, and quantum optics.
The Braun Center for sub micron research is an integral part of the department. It is a modern and well equipped center, with growth (three MBE's) and characterization systems, which allows to conduct experiments on sub micron semiconductor structures under high magnetic fields, conventional and high temperature superconductors, and nanowires made of carbon nanotubes and semiconductor nanowires.

Department of Computer Science and Applied Mathematics

Head Prof. Ronen Basri

Picture of Prof. Ronen Basri
Head

Prof. Ronen Basri

Office +972-8-934-2809

Overview

The principal interests of the department lie in the areas of computer science and applied mathematics. Research areas include (but are not limited to) algorithms, their design and analysis; biological applications, bioinformatics, system biology, biological modeling; computational complexity, probabilistic proof systems, hardness of approximation, circuit complexity, combinatorial games; computer vision, image processing; cryptography; differential equations; distributed and parallel computing; dynamical systems; fluid dynamics; logic of programs, specification methodologies; machine learning and mathematical statistics; numerical analysis; randomness and its relation to computation; robotics and motion control; visual perception and brain modeling.

The departmental computer facilities include multiple PCs, multiple unix servers, two Linux clusters with multiple nodes, and large data storage systems. In addition, the vision laboratories, robotics laboratories and computational biology laboratories have a combination of experimental equipment and large-scale computing clusters.

Pages